scholarly journals CLINICO-PATHOLOGICAL STUDY OF SINONASAL MASSES

2020 ◽  
pp. 33-35
Author(s):  
Alokendu Bose ◽  
Indranil Khatua ◽  
Nayana Sengupta ◽  
Debarshi Jana
Keyword(s):  
Clinical Presentation ◽  
Disease Process ◽  
Nasal Discharge ◽  
Anatomical Location ◽  
Histopathological Diagnosis ◽  
Main Hospital ◽  
Sex Risk ◽  
The Face ◽  
Eye Symptoms ◽  
The Brain

INTRODUCTION The nose is the most prominent part of the face with substantial aesthetic and functional significance. It is one of the few organs of body invested with an aura of emotional and cultural importance. Anatomical location of the nose and it passage have been regarded as the direct avenue to the brain, man’s source of intelligence and spirituality. AIMS AND OBJECTIVES To study the incidence, clinical presentation and pathological profile of various types of sinonasal masses at Tata Main Hospital, Jamshedpur, Jharkhand. To detect the variation of clinical presentation of sinonasal masses in relation to Age, Sex, Risk factors and Occupation, clinical presentation and the histopathological diagnosis of sinonasal masses. Compare the results of this study with the results of the previous workers. MATERIAL & METHODS: This Prospective, observational study was done in the department of Otorhinolaryngology, Tata Main Hospital, Jamshedpur, Jharkhand. 90 patients presenting with the features of nasal obstruction, nasal discharge, headache, anosmia / hyposmia, epistaxis, facial deformity, ear & eye symptoms will be evaluated by taking history and thorough ENT and head and neck examination(including nasal endoscopy) and subjecting them for the procedure. RESULT Out of 90 patients, 59(65.56%) were males and 31(34.44%) were females. In our study, among non neoplastic masses 34 were male and 26 were female. For non-neoplastic lesions the average age of presentation was 36.2 years. Mean age of presentation was 37.21 years. CONCLUSION Emergence of newer surgical, medical and radiological intervention have open up a new chapter with these type of patients. . Awareness regarding the disease process and health education should be provided to people regarding smoking, maintenance of hygienic condition and utilization of health facilities.

Face-selective Activation in a Congenital Prosopagnosic Subject

2003 ◽  
Vol 15 (3) ◽  
pp. 419-431 ◽  
Author(s):  
Uri Hasson ◽  
Galia Avidan ◽  
Leon Y. Deouell ◽  
Shlomo Bentin ◽  
Rafael Malach
Keyword(s):  
Brain Activity ◽  
Brain Lesion ◽  
Temporal Cortex ◽  
Occipital Cortex ◽  
Face Identification ◽  
Control Group ◽  
Anatomical Location ◽  
Congenital Prosopagnosia ◽  
The Face ◽  
The Brain

Congenital prosopagnosia is a severe impairment in face identification manifested from early childhood in the absence of any evident brain lesion. In this study, we used fMRI to compare the brain activity elicited by faces in a congenital prosopagnosic subject (YT) relative to a control group of 12 subjects in an attempt to shed more light on the nature of the brain mechanisms subserving face identification. The face-related activation pattern of YT in the ventral occipito-temporal cortex was similar to that observed in the control group on several parameters: anatomical location, activation profiles, and hemispheric laterality. In addition, using a modified vase – face illusion, we found that YT's brain activity in the face-related regions manifested global grouping processes. However, subtle differences in the degree of selectivity between objects and faces were observed in the lateral occipital cortex. These data suggest that face-related activation in the ventral occipito-temporal cortex, although necessary, might not be sufficient by itself for normal face identification.

scholarly journals Cysticercal Brain Abscess: A Distinct Entity Mimicking Pyogenic Brain Abscess.

2021 ◽  
Author(s):  
Radhika Mhatre ◽  
Subhas Konar ◽  
Nishanth S. ◽  
Anita Mahadevan ◽  
B. Indira Devi
Keyword(s):  
Brain Abscess ◽  
Clinical Presentation ◽  
Surgical Excision ◽  
Histopathological Diagnosis ◽  
Rare Entity ◽  
Radiological Findings ◽  
Distinct Entity ◽  
Solitary Lesion ◽  
Short Course ◽  
The Brain

Abstract Cysticercal brain abscess is a rare entity with the clinical presentation and radiological findings closely mimicking a pyogenic abscess. We report three cases of cysticercal abscess presenting as solitary lesion in the brain with radiological appearance like an abscess. All the patients underwent excision of the lesion with histopathological diagnosis of cysticercal brain abscess. The clinical outcome was satisfactory after surgical excision. Cysticercal abscess, though rare, should be considered as a differential diagnosis of a solitary rim-enhancing lesion, mainly if the patients belong to the endemic zone of neurocysticercosis. Surgical excision with or without a short course of the anti-parasitic agent is the treatment of choice.

About the Brain, the Face, and Emotion

1984 ◽  
Vol 29 (7) ◽  
pp. 567-568
Author(s):  
Gilles Kirouac
Keyword(s):  
The Face ◽  
The Brain

scholarly journals Mechanisms of Neurodegeneration in Various Forms of Parkinsonism—Similarities and Differences

Cells ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 656
Author(s):  
Dariusz Koziorowski ◽  
Monika Figura ◽  
Łukasz M. Milanowski ◽  
Stanisław Szlufik ◽  
Piotr Alster ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Tau Protein ◽  
Protein Gene ◽  
Clinical Presentation ◽  
Neuronal Loss ◽  
Corticobasal Degeneration ◽  
Inflammatory Factors ◽  
Parkinsonian Disorders ◽  
Genetic Features ◽  
The Brain

Parkinson's disease (PD), dementia with Lewy body (DLB), progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and multiple system atrophy (MSA) belong to a group of neurodegenerative diseases called parkinsonian syndromes. They share several clinical, neuropathological and genetic features. Neurodegenerative diseases are characterized by the progressive dysfunction of specific populations of neurons, determining clinical presentation. Neuronal loss is associated with extra- and intracellular accumulation of misfolded proteins. The parkinsonian diseases affect distinct areas of the brain. PD and MSA belong to a group of synucleinopathies that are characterized by the presence of fibrillary aggregates of α-synuclein protein in the cytoplasm of selected populations of neurons and glial cells. PSP is a tauopathy associated with the pathological aggregation of the microtubule associated tau protein. Although PD is common in the world's aging population and has been extensively studied, the exact mechanisms of the neurodegeneration are still not fully understood. Growing evidence indicates that parkinsonian disorders to some extent share a genetic background, with two key components identified so far: the microtubule associated tau protein gene (MAPT) and the α-synuclein gene (SNCA). The main pathways of parkinsonian neurodegeneration described in the literature are the protein and mitochondrial pathways. The factors that lead to neurodegeneration are primarily environmental toxins, inflammatory factors, oxidative stress and traumatic brain injury.

scholarly journals Time to Be SHY? Some Comments on Sleep and Synaptic Homeostasis

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Giulio Tononi ◽  
Chiara Cirelli
Keyword(s):  
Synaptic Strength ◽  
Universal Function ◽  
Systematic Bias ◽  
Synaptic Homeostasis ◽  
The Face ◽  
Essential Function ◽  
Function Of Sleep ◽  
The Brain

Sleep must serve an essential, universal function, one that offsets the risk of being disconnected from the environment. The synaptic homeostasis hypothesis (SHY) is an attempt to identify this essential function. Its core claim is that sleep is needed to reestablish synaptic homeostasis, which is challenged by the remarkable plasticity of the brain. In other words, sleep is “the price we pay for plasticity.” In this issue, M. G. Frank reviewed several aspects of the hypothesis and raised several issues. The comments below provide a brief summary of the motivations underlying SHY and clarify that SHY is a hypothesis not about specific mechanisms, but about a universal, essential function of sleep. This function is the preservation of synaptic homeostasis in the face of a systematic bias toward a net increase in synaptic strength—a challenge that is posed by learning during adult wake, and by massive synaptogenesis during development.

scholarly journals Aprosopia/holoprosencephaly in a stillborn puppy: when the face predicts the brain

2021 ◽  
Vol 9 (1) ◽  
pp. 7-10
Author(s):  
Clairton Marcolongo Pereira ◽  
Tayná B. Silva ◽  
Laiz Zaché Roque ◽  
Bárbara Barros ◽  
Luiz Alexandre Moscon ◽  
...  
Keyword(s):  
The Face ◽  
The Brain

scholarly journals Temporal gliosarcoma: case report and review of literature

2015 ◽  
Vol 22 (1) ◽  
pp. 112-116
Author(s):  
Amit Agrawal ◽  
Vissa Shanthi ◽  
Baddukonda Appala Ramakrishna ◽  
Kuppili Venkata Murali Mohan
Keyword(s):  
Case Report ◽  
Median Survival ◽  
Glial Cells ◽  
Primary Tumor ◽  
Clinical Presentation ◽  
Spindle Cell ◽  
Review Of Literature ◽  
Future Studies ◽  
Aggressive Tumor ◽  
The Brain

Abstract First characterized by Stroebe, the gliosarcomas are highly malignant and rare primary tumor of the brain composed of neoplastic glial cells in association with spindle cell sarcomatous elements (biphasic tissue patterns). In spite of being recognized as two different pathologies studies have not shown any significant differences between gliosarcoma and glioblastoma with regard to age, sex, size, clinical presentation, and median survival. In summary, gliosarcoma is an aggressive tumor with a propensity to recur and re-grow with poor outcome. Future studies are needed to understand the true pathology of these biphasic tumors.

Juvenile-onset Neuronal Ceroid-Lipofuscinosis in Rambouillet Sheep

1994 ◽  
Vol 31 (1) ◽  
pp. 48-54 ◽  
Author(s):  
J. F. Edwards ◽  
R. W. Storts ◽  
J. R. Joyce ◽  
J. M. Shelton ◽  
C. S. Menzies
Keyword(s):  
Nervous System ◽  
Neuronal Degeneration ◽  
Neuronal Ceroid Lipofuscinosis ◽  
Disease Process ◽  
Autosomal Recessive Inheritance ◽  
Human Beings ◽  
Juvenile Onset ◽  
Ceroid Lipofuscinosis ◽  
Disease States ◽  
The Brain

Two, 8-month-old Rambouillet half-sister ewes with signs of visual loss and decreased mentation were examined. Ewe No. 1 was necropsied at 10 months of age, and alter being held under observation for a further 6 months, ewe No. 2 was necropsied at 16 months of age. At that time, the ewe was blind and severely depressed. Both ewes had deposition of an autofluorescent lipopigment, identified as ceroid-lipofuscin, in neurons of the brain, spinal cord, eye, and dorsal root ganglia. The disease process was progressive and characterized by deposition of lipopigment with neuronal degeneration and severe fibrillary aslrogliosis. This progressive loss of neurons in the older ewe led to severe retinal degeneration. No pigment was observed in cells outside of the nervous system and eye. Controlled breeding studies have shown that this disease has an autosomal, recessive inheritance. The disease referred to here as juvenile-onset neuronal ceroid-lipofuscinosis of Rambouillet sheep is unlike the majority of the hereditary ceroid-lipofuscinoses that occur in human beings and animals in that only the nervous system is affected. Therefore, this disease could serve as an excellent model for the study of lipopigment deposition that affects the nervous system as a result of various disease states and during aging.

Preserving Integrity in the Face of Performance Threat

2012 ◽  
Vol 23 (12) ◽  
pp. 1455-1460 ◽  
Author(s):  
Lisa Legault ◽  
Timour Al-Khindi ◽  
Michael Inzlicht
Keyword(s):  
Error Detection ◽  
Error Monitoring ◽  
Error Related Negativity ◽  
Threatening Information ◽  
Electrophysiological Responses ◽  
The Face ◽  
And Performance ◽  
The Impact ◽  
The Brain

Self-affirmation produces large effects: Even a simple reminder of one’s core values reduces defensiveness against threatening information. But how, exactly, does self-affirmation work? We explored this question by examining the impact of self-affirmation on neurophysiological responses to threatening events. We hypothesized that because self-affirmation increases openness to threat and enhances approachability of unfavorable feedback, it should augment attention and emotional receptivity to performance errors. We further hypothesized that this augmentation could be assessed directly, at the level of the brain. We measured self-affirmed and nonaffirmed participants’ electrophysiological responses to making errors on a task. As we anticipated, self-affirmation elicited greater error responsiveness than did nonaffirmation, as indexed by the error-related negativity, a neural signal of error monitoring. Self-affirmed participants also performed better on the task than did nonaffirmed participants. We offer novel brain evidence that self-affirmation increases openness to threat and discuss the role of error detection in the link between self-affirmation and performance.

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