scholarly journals EVALUATION OF UPPER GASTROINTESTINAL LESIONS IN ANEMIA WITH AND WITHOUT GASTROINTESTINAL SYMPTOMS:-PROSPECTIVE STUDY.

2020 ◽  
pp. 1-3
Author(s):  
Shantaram Dattatray Gulve ◽  
Mandar Doiphode ◽  
Kalpesh Patil

Background: Anemia is a global public health problem affecting both developing and developed countries at all ages. Iron deficiency is common cause of anemia. It is either poor intake or chronic gastrointestinal bleeding. Goal of this study is to identify the prevalence of upper GI lesions, identified by OGDscopy in patients in anemia with or without gastrointestinal symptoms. Methods: In this prospective study we analysed data of 100 patients who underwent OGDscopy procedure in tertiary care centre. On OGDscopy study 33% had normal GIT and 67% had GI lesions majority were erosive gastritis, erosive oesophagitis gastric and duodehal ulcers, other lesions like congestive gastropathy reflux oesophagitis and malignant lesions like carcinora of stomach and carcinora of oesophagus. Conclusion: OGDscopy procedure is essential in evaluating lesions of upper gastrointestinal tract in anemia for diagnostic and therapeutic purpose.

2019 ◽  
Vol 6 (9) ◽  
pp. A459-462
Author(s):  
Mridula Kamath ◽  
◽  
Suchithra A Shetty ◽  
Shreesha Khandige ◽  
◽  
...  

Author(s):  
Angchuman Chetia ◽  
Rupali Baruah

Background: Oral cancer is a disease of antiquity. This chronic disease is a public health problem both in developing as well as developed countries and is among the top three cancers in India. In Assam, some aspects of traditional lifestyle and dietary habits are likely to contribute to the increasing cancer trend.Methods: The hospital-based case control study was undertaken in AMCH, Dibrugarh. Study subjects included were clinically and histopathologically confirmed new cases of oral cancer attending the hospital during the period of June 2018 to May 2019 and equal number of age and sex matched controls. The total sample size including both cases and controls was 116. A predesigned pretested schedule was used for collecting data.Results: Tobacco chewing was the strongest risk factor associated with oral cancer with odds ratio of chewers 6.13 (95% CI, 2.26-16.60). Statistically significant association was seen with duration, age at start, frequency of chewing and retaining tobacco quid overnight. The risk of developing oral cancer was 3.60 times higher (95% CI of (1.45-8.93)) among smokers compared to non-smokers.Conclusions: The incidence of oral cancer is on the rise. Due to the well-established role of lifestyle factors in the development of oral cancer, they should be considered an important cause of avoidable morbidity and mortality in India, and their prevention should be an important target of public health initiatives.


Author(s):  
Dr. Renu Gupta ◽  
Dr. Rashmi Kumari ◽  
Dr. Shaily Agarwal ◽  
Dr. Kiran Pandey ◽  
Dr. Neena Gupta ◽  
...  

Among the viral infections affecting the liver in pregnancy, Hepatitis C though uncommon now is recognized to be a serious global public health problem affecting 170 million people worldwide I .e. 3% of the population [1]. The prevalence of anti-HCV antibody in pregnant women in developed countries ranges from 0.14 to 4.4%, whereas the seroprevalence in Indian pregnant female population is 1.03% [2,3,4].Following the decreasing transmission of HCV by blood -transfusion, intravenous drug use has now become the primary route of new HCV infections in adults while mother to child transmission (MTCT) is the major route of new infections in young children in the developed as well as in developing countries.[5]Approximately 7–8% of hepatitis C virus-positive women transmit this virus to their offspring [6]mainly because they are ignorant about this infection and unaware of their status. The natural course of hepatitis C is a progression from acute hepatitis to chronic hepatitis, which occurs in 55%-85 % of patients.


JMS SKIMS ◽  
2020 ◽  
Vol 23 (1) ◽  
pp. 48-49
Author(s):  
Javaid Ahmad Bhat ◽  
Shariq Rashid Masoodi

Apropos to the article by Dr Bali, titled “Mupirocin resistance in clinical isolates of methicillin-sensitive and resistant Staphylococcus aureus in a tertiary care centre of North India” (1), the authors have raised important issue of emerging antimicrobial resistance (AMR). Antimicrobial resistance is an increasingly serious threat to global public health that requires action across all government sectors and society. As per WHO, AMR lurks the effective prevention and management of an ever-increasing spectrum of infections caused by bacteria, parasites, fungi and viruses. Novel resistance mechanisms are emerging and spreading globally, threatening the man’s ability to treat common infectious diseases.


2020 ◽  
Vol 11 (5) ◽  
pp. 54-60
Author(s):  
Apurba Mandal ◽  
Shibram Chattopadhyay ◽  
Sushanta Mondal ◽  
Arunava Biswas

Background: Adnexal mass is a common presentation in today’s gynecological practice. The incidence of ovarian cancer is increasing day by day and diagnosis is often difficult to be made pre operatively with inadequate surgical exploration is a regular occurrence. Aims and Objectives: To assess and validate the importance of RMI-3 score as pre-operative diagnostic tool of differentiating benign from malignant adnexal mass for starting first line therapy of ovarian cancer and to find out the incidences of ovarian malignancy among study population. Material and Methods: The study was conducted in the Department of Gynecology and Obstetrics on (n=115) patients attending GOPD and indoor with adnexal mass fulfilling the inclusion and exclusion criteria using purposive sampling technique. All the selected cases underwent ultrasonography and serum CA- 125 level estimation necessary for calculating RMI score. A score of >200 was taken as suggestive of malignancy and confirmatory diagnosis was performed by histopathological examination obtained from staging laparotomy of adnexal mass. The individual scores were then correlated with final outcomes with statistical analyses. Results: The study revealed benign ovarian tumors are more under 50 years (78.46%) and patients with normal BMI are diagnosed with maximum of malignancy (n = 28). History of tubal ligation carried less risk of malignancy (p<0.0001). Histologically malignant tumors found mostly in 71.4% postmenopausal group whereas 94.1% benign pathology were present in perimenopausal group and there is no association found between parity and histopathology (p=0.058). Bilateral (p=0.013), multilocular (p=0.000) tumors with solid areas (p<0.0001) and thick papillary projections (p<0.0001) had statistically significant association with malignant lesions. RMI score (>200) had more efficacy than serum CA-125 level (>46) in differentiating malignant lesions from benign one in terms of specificity (96% vs 83.87%) and positive predictive value (95% vs 79.17%). Conclusions: RMI-3 score is a simple, reliable and effective tool in differentiating benign from malignant adnexal masses thereby help in quick referral and management of cases with increase chances of survival of the patients.


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