scholarly journals PREVALENCE AND RISK FACTORS OF DRY EYE AMONG PATIENTS OF A TERTIARY CARE CENTRE IN EASTERN INDIA

2021 ◽  
pp. 5-7
Author(s):  
Nilesh Mohan ◽  
Vandana Parasar ◽  
Ankita Singh ◽  
Rakhi Kusumesh

AIM: To determine the prevalence and risk factors of dry eye among patients of a tertiary care centre in eastern India. Symptoms of dry eye are encountered as one of the most frequent complains among the patients attending the outpatient department in ophthalmology commonly presenting as ocular discomfort, burning sensation and foreign body sensation.Prevalence of this entity is still not known in our study population due to lack of specificity of symptoms and diagnostic criteria. MATERIALS AND METHODS: A prospective, observational, cross-sectional study was conducted among patients attending ophthalmology OPD in a tertiary care teaching hospital of Bihar. 4116 (16.64%) patients with dry eye symptoms were examined after taking informed consent. RESULTS: 1620 (6.55%) patients were found to have dry eye based on McMonnies questionnaire, Schirmer's test and tear film breakup time.There were 1180 female and 440 male with dry eye.Male to female ratio was 2.7:1.Non-tribals were affected more commonly than tribals. Students, outdoor workers and office worker with professional constituted over fifty percent of dry eye cases. CONCLUSION: Prevalence of dry eye was more in females and elderly as compared to male and younger population respectively.Burning sensation and ocular discomfort was the most common presenting complains.

2021 ◽  
pp. 10-11
Author(s):  
Akhilesh Behra

BACKGROUND- Psoriasis is chronic common papulosquamous disorder. Its aetiology included various environmental and genetic factors. In genetics, HLA-Cw6 is most commonly associated with psoriasis. Childhood psoriasis is also common in worldwide population. However, very few studies done on epidemiological data and HLA-Cw6 analysis in childhood psoriasis patients. AIMS AND OBJECTIVE- Clinicoepidemiological study of childhood psoriasis patients and its association with HLA-Cw6 in a tertiary care centre of Eastern India MATERIALAND METHOD- We conducted a cross-sectional study in a tertiary care centre and recruited 20 patients of psoriasis with age group below 18 years after taking proper consent. Clinical history and blood was taken from them and HLA-Cw6 analysis was done by PCR method. Data compilation was done by Microsoft excel using SPSS software. RESULTS- A total of the 20 childhood psoriasis patients, 9 were males and 11 were females. Generalized plaque type psoriasis (N=19) is commonest followed by guttate psoriasis (N=1). None of the patients had arthalgia. Family history was present in only 3 patients. Higher numbers of childhood psoriasis patients (N=14) were positive for HLA-Cw6. Also Higher numbers of females (N=10) were positive for HLA-Cw6. ve patients had nail changes. CONCLUSION- We found HLA-Cw6 is strongly associated with childhood psoriasis and also HLA-Cw6 frequency is higher in female than male childhood psoriasis patients.


Author(s):  
Shrusti Parmar ◽  
Nalini Sharma ◽  
Vimla Dhakar

Background: One among the three chief obstetric causes of bleeding in first trimester, ectopic pregnancy is the first thing to rule out as a gestation is suspected. The present study observes and analyses sociodemographic distribution, risk factors, presentation, diagnosis and treatment modalities in a tertiary care centre.Methods: An observational cross-sectional study, conducted among patients who were diagnosed and managed in department of obstetrics and gynaecology of a tertiary care centre. Data analyzed and explained as frequency, percentage, mean and standard deviation.Results: Age group between 21 to 30 years (69.9%) and multigravida (68.5%) are high risk for ectopic pregnancy (EP). Menstrual history was regular in 86.3%. Risk factors identified were previous abortion (30%) and history of pelvic inflammatory disease (30%). In 80.9% pain in abdomen was presenting complaints followed by bleeding per vaginum (60%), amenorrhoea (60%) and nausea and vomiting (32.9%). Right salpingectomy was most common in 43.8%, followed by left salpingectomy in 28.8%, methotrexate in 15.1%, left salpingo-ophorectomy in 5.5%, right salpingo-opherectomy in 5.5% and removal of tubal abortion in 1.3% patients. Laparoscopy was chosen route in majority 64.4% patients.Conclusions: Ectopic pregnancy - a gynecological catastrophe as well as a major challenge to the reproductive performance of women worldwide, should be considered a relevant public health issue. By providing adequate materials, manpower, well-equipped health facilities as well as a prompt and efficient referral system, good access roads and efficient transportation, will ensure early presentation in hospitals and prompt management of cases.


2019 ◽  
Vol 8 (17) ◽  
pp. 1376-1380
Author(s):  
Ramesh Bhattacharyya ◽  
Shantanu Ghosh ◽  
Kartick Chandra Ghosh ◽  
Sarbajit Ghosh ◽  
Suman Das ◽  
...  

2012 ◽  
Vol 5 ◽  
pp. CMAMD.S9803 ◽  
Author(s):  
Al-Bishri Jamal ◽  
Al-Harthi Salma ◽  
Al-Sofiani Wafa ◽  
Almutairi Ghadah ◽  
AlOsaimi Roaa

Objective To determine the appropriateness (both indications and adequate dosage regimen via creatinine clearance estimation) of allopurinol by physicians of different specialties in a tertiary care centre. Patients and Methods In this cross sectional study computerized clinical records of 156 adult patients who were prescribed allopurinol from 12th November to 11th December, 2011 were retrieved from Al Hada Hospital Taif Saudi Arabia. Main outcome variables were approprsiate indications of allopurinol, prescribing physician's specialty, and dosage of allopurinol. The prescribed dosages were categorized into correct and incorrect dose adjustments based on creatinine clearance estimation. The SPSS version 16 was utilized for data analyses. Results The mean (±SD) age was 58.15 (±14.99) years. There were 105 (67.3%) males and 51 (32.7%) females with male to female ratio being 2:1. Allopurinol was frequently prescribed by nephrologists and family physicians in this study. Out of 156 patients, 46 (29.5%) patients received allopurinol with appropriate indications. Eighty-five (54.5%) patients were received allopurinol without dose adjustment based on their creatinine clearance estimation; among them, 21 (13.5%) received allopurinol with appropriate indications. Conclusion The inappropriate use of allopurinol (both the indication and prescribed dosage) is still a major problem in a large tertiary care centre. Furthermore, the specialty of physicians is also a contributory factor in this inappropriateness.


2021 ◽  
Vol 5 (6) ◽  
pp. 198-202
Author(s):  
Kavya M Alalageri ◽  
Shobha Shobha ◽  
Ranganath TS

Context: A high suicide rate is an index of social disorganization. In India, it is the second leading cause of death among 15-29 years age group. Young age, female sex, poor education, unemployment and socio economic deprivation are some of the potential risk factors. Aim: To assess the cause of present suicide intent and socio-demographic profile in patients with attempted suicide in a tertiary care centre. Settings and design: Study setting in tertiary care centre, Bengaluru and a Cross-sectional study design. Methods and material: A Cross Sectional Study was conducted among 476 suicide attempted patients by Convenient sampling from January 2016 to May 2017. Data was collected by using a pretested, semi-structured questionnaire. Statistical analysis: Descriptive statistics and inferential statistics if required. Results: Mean age of study participants was 30.65+0.75 years. Most of the suicide victims (82.97%) were from nuclear families.24.57%of study participants had family history of suicide.49.66% of them had a suicidal intent during the past 12 months and only 26.89% of them sought professional help. Conclusion: Suicides and attempted suicides are slowly but steadily assuming the levels of a public health problem caused by multiple factors. Hence there is a need to address the risk factors for suicide attempts and preventing them by taking proper measures at individual, family and societal level.


Author(s):  
Nitin Gupta ◽  
Sandeep Joshi ◽  
Udit Narang ◽  
Rosy Bala Gupta ◽  
Ruby Sharma ◽  
...  

Objective: Stroke is one of the leading causes of mortality and long-term disability in both developed and developing countries. Serum homocysteine level is one of the emerging modifiable risk factors for atherosclerosis which may result into a cerebrovascular accident. This study was designed to study the association of Serum Homocysteine level with the development of acute stroke at a rural tertiary care centre in North India.Methods: The present study was a prospective cross-sectional study conducted in the Department of Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala. The study population included 100 patients presenting with Stroke (either ischemic or hemorrhagic) in the indoor and outdoor facilities in the Department of Medicine. 50 age and sex-matched healthy individuals were taken as controls. Serum total Homocysteine level was measured in all the cases and controls.Results: Majority of the patients suffered from ischemic stroke (78%), while only 22% patients had hemorrhagic stroke. The mean Serum Homocysteine level in stroke patients (19.88±8.78 μmol/l) was significantly higher than in controls (10.48±4.39 μmol/l) (p<0.01). In a subgroup analysis, stroke patients with a positive history of smoking had significantly higher homocysteine level as compared to non-smokers (p<0.05).Conclusion: Increased level of Serum Homocysteine is significantly associated with risk of cerebrovascular accident, which is independent of the risk attributed to traditional risk factors. 


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