scholarly journals Fibrin Glue Versus Autologous Serum for Conjunctival Autograft Fixation in Pterygium Surgery

2020 ◽  
Vol 36 (1) ◽  
Author(s):  
Abdul Rafe ◽  
Saquib Naeem ◽  
Tariq Munawar
Keyword(s):  
Fibrin Glue ◽  
Sampling Technique ◽  
Autologous Serum ◽  
Bulbar Conjunctiva ◽  
Dry Eyes ◽  
Conjunctival Autograft ◽  
Quasi Experimental ◽  
Group A ◽  
Pterygium Excision ◽  
Group B

Purpose:  To compare the outcomes of conjunctival autograft fixation using autologous serum vs fibrin glue to cover the bare sclera in pterygium excision surgery. Study Design:  Quasi experimental study. Place and Duration of Study:  The study was conducted in Ophthalmology Department of CMH Kharian from April 2018 to November 2018. Material and Methods:  Forty patients with primary pterygium were selected by convenient sampling technique. Patients with recurrent Pterygia and moderate to severe dry eyes, keratitis or secondary to trauma were excluded. The patients were divided into two groups, group A treated with fibrin glue and group B treated with autologous serum technique. All patients underwent pterygium excision under topical anaesthesia. The conjunctival autograft was removed from superior temporal bulbar conjunctiva to cover the scleral bed produced by pterygium excision. Post operatively the patients were followed-up for three months to assess the fixation or otherwise. Data was noted and analysed by using SPSS version 23. Results:  The graft was taken-up nicely in most of the cases. The patients were followed up for three months after surgery. The frequency of graft lost in Group A and Group B was noted as n = 8 (40%) and n = 1 (5%), respectively (p = 0.008). The only other complication was recurrence of pterygium which was n = 5 (25%) and n = 3 (15%), in Group A and Group B, respectively (p = 0.429). No case of infection was noted. Conclusion:  Fixation of conjunctival autograft with autologous serum is a safe and effective method and potential alternative of fibrin glue technique.

scholarly journals Outcome Of The Use Of Autologous Blood Serum, Fibrin Glue And Vicryl Suture In Conjunctival Autograft Transplant Following Pterygium Surgery.

2020 ◽  
Vol 7 (06) ◽  
pp. 4860-4864
Author(s):  
BRIJESH SINGH ◽  
MEENU BABBER ◽  
IFSA SAMI
Keyword(s):  
Fibrin Glue ◽  
Autologous Blood ◽  
Autologous Serum ◽  
P Value ◽  
Conjunctival Autograft ◽  
Suture Group ◽  
Group A ◽  
Group B ◽  
Conjunctival Autografting ◽  
Postoperative Discomfort

Background: Pterygium is a common ophthalmological problem in India. Excision of pterygium with conjunctival autograft is the main line of treatment. Many modifications of surgical techniques have been tried like conjunctival autografting with fibrin glue, sutures and autologous serum. All these modalities have their pros and cons. We compared these techniques for conjunctival autografting following pterygium surgery. Methods: A randomized interventional study was performed on 60 eyes with primary nasal pterygium. After pterygium excision, the bare sclera was covered with a conjunctival autograft, which was fixed using autologous blood serum(in Group A, n=20), fibrin glue(in Group B, n=20) and vicryl suture (8-0) (in Group C, n=20). The patients were examined on postoperative Day 1, 1 week, 1month, 3 month and 6 month. The main outcome measures were operative time ,autograft stability, postoperative discomfort, autograft thicknes, pterygium recurrence and granuloma formation. Results: The mean operative time was significantly shorter in group A(23.60 min) followed by Group B (25.20 min) and Group C(28.15 min)(p-value <0.0001).Postoperative discomfort measured on visual analogue scale was minimal in fibrin group (p-value=0.0008) and maximum in suture group. Graft displacement was found in 2(10%) patient in autologous blood group (p value=0.349) while Graft oedema, granuloma & recurrence was noted in suture group only(p value=0.362). Conclusions: The conjunctival autografting with fibrin glue proved to be better method than autologous serum and suture, as it had very less postoperative discomfort, no recurrence, minimal edema and less graft displacement.

scholarly journals Comparison between Autologous Blood and Fibrin Glue for Adhering Conjunctival Autografts after Pterygium Excision- A Randomised Clinical Trial

2021 ◽  
Author(s):  
Mona Sune ◽  
Pradeep Sune
Keyword(s):  
Clinical Trial ◽  
Fibrin Glue ◽  
Autologous Blood ◽  
Randomised Clinical Trial ◽  
Mild Degree ◽  
Group A ◽  
Pterygium Surgery ◽  
Pterygium Excision ◽  
Group B

Introduction: Fibrin glue is a biological tissue adhesive and acts on the principle of final stages of the coagulation cascade. The cost of commercially available products is very high and not affordable for the patients of low socio-economic strata. As an alternative, pterygium surgery was done using patient’s own blood to adhere the conjunctival autograft to scleral bed by the process of coagulation of fibrin from the oozing blood from the blood vessels under the flap. Aim: To compare autologous blood and fibrin glue for adhering conjunctival autografts after pterygium excision. Materials and Methods: It was a randomised clinical trial. Total 97 subjects with primary pterygium who visited the Ophthalmology Department were randomised into two groups. In group A (n=31), patients had undergone pterygium excision wherein conjunctival autograft was attached by fibrin glue. In group B (n=66) the graft was attached by autologous blood present on the scleral bed. Mean operative time for the procedures were compared. Follow- up was done for 12 months and all subjects were examined for postoperative pain, foreign body sensation, inflammation, graft stability and recurrence. Results: The mean age of patients in group A was 48.32±14.3 years (21-65 years), and in group B was 54.48±15.67 (23-74 years). Mean operating time in group A was 23.21±9.4 minutes and 13.7±4.3 minutes in group B, (p-value=0.001). Postoperative pain of mild degree was present in all the 31 (100%) subjects of group A. In group B, pain was absent in 32 (48.5%) and mild degree in 34 (51.5%) subjects. No recurrence was found in both the groups. Mean follow-up period was 11.4 months. Conclusion: This study concludes that autologous blood is a useful alternative method for graft attachment in pterygium surgery without the untoward complications related to fibrin glue.

scholarly journals Comparing Adjuvant Beta Radiation, Mitomycin C, and Conjunctival Autograft in Primary Pterygium Treatment, a Three-year Follow-up Study

2021 ◽  
Vol 14 (1) ◽  
pp. 82-87
Author(s):  
Khalil M. Al-Salem ◽  
Ahmad T.S. Saif ◽  
Passant S. Saif
Keyword(s):  
Postoperative Complications ◽  
Mitomycin C ◽  
Recurrence Rate ◽  
University Hospital ◽  
Beta Radiation ◽  
Conjunctival Autograft ◽  
Group A ◽  
Pterygium Excision ◽  
Group B ◽  
Primary Pterygium

Purpose: To compare the recurrence rate of primary pterygium surgery after the adjuvant use of Beta radiation, Mitomycin C, and conjunctival autograft. Methods: 180 eyes of 180 patients were included in the study. All cases had primary pterygium excision following the use of adjuvant therapy of Beta radiation or Mitomycin C (0.02% for 5 minutes) or conjunctival autograft. The study was conducted at Fayoum University Hospital, Fayoum, Egypt, and Misr University Hospital. The patients were randomly divided into three groups, with each group comprising 60 patients. Group (A) included patients treated with Beta radiation following Pterygium excision, group (B) patients had primary pterygium excision with the application of 0.02% Mitomycin C for 5 minutes, and group (C) patients had conjunctival autograft to cover the bare area after pterygium excision. Patients were followed up for three years postoperatively. Results: group A had the highest recurrence rate (33.3%) followed by group B (13.3%), and finally group C presented a recurrence rate of 6.7%. Group B showed the highest rate of intra-ocular postoperative complications, while no intra-ocular complications were recorded in group C. Common complications in groups A and B were scleral melting, keratitis, and Dellen formation. Conclusion: Using conjunctival autograft after primary pterygium excision gives the best results regarding the rate of recurrence and postoperative complications. Meanwhile, B-radiation or Mitomycin C did not prove to be as good.

scholarly journals Effects of Aerobics Versus Core Stability Exercises for the Management of Primary Dysmenorrhea

2021 ◽  
Vol 15 (8) ◽  
pp. 2442-2444
Author(s):  
Nighat Nasrullah Khan ◽  
Saima Riaz ◽  
Rehan Ramzan Khan ◽  
Hira Mannan ◽  
Sobia Ghafoor ◽  
...  
Keyword(s):  
Rating Scale ◽  
Sampling Technique ◽  
Core Stability ◽  
Primary Dysmenorrhea ◽  
Menstrual Cycles ◽  
Quasi Experimental ◽  
Group A ◽  
Numeric Pain Rating Scale ◽  
Group B ◽  
Pain Rating Scale

Objective: To compare the effects of aerobics and core stability exercises for the management of primary dysmenorrhea. Methodology: The study design was quasi-experimental, conducted in Yahya gym, Lahore, from February 2019 to July 2019. The sampling technique employed was non-probability convenient sampling with a sample size of 42 females within 18-30 years who had primary dysmenorrhea. The subjects were assigned into two groups. Group A was treated with aerobic exercises, while Group B was treated with core stability exercises with eight weeks workout plan and the results of three menstrual cycles were recorded. Stretching maneuvers were added as a standard treatment to both groups. Data were collected after 12 weeks and recorded for three menstrual cycles. Numeric Pain Rating Scale (NPRS) was used to measure pain intensity. Data were analyzed using IBM SPSS v.25. Results: Mean age of group A vs. group B participants was 25.23 ±2.64 vs. 21.38±3.41 years respectively. Mean BMI score of group A participants was 21.38±2.14 while for group B participants mean BMI score was 21.65±1.99 Kg/m2. Conclusion: This study concludes that both aerobic exercises and core stability exercises are effective to reduce the intensity of pain in primary dysmenorrhea. However aerobic exercises showed relatively better results in term of mean difference of NPRS score across both groups. Keywords: Menstruation, Primary dysmenorrhea, Exercise, Pain.

scholarly journals SUPRACONDYLAR FRACTURES

2006 ◽  
Vol 13 (02) ◽  
pp. 244-252
Author(s):  
MUKHTAR AHMAD TARIQ ◽  
MUHAMMAD ShAFI ◽  
ASGHAR ALI
Keyword(s):  
Sampling Technique ◽  
Supracondylar Fractures ◽  
Superficial Wound ◽  
Quasi Experimental ◽  
Experimental Type ◽  
Group A ◽  
Carrying Angle ◽  
Pin Tract Infection ◽  
Group B ◽  
Condylar Fractures

Objective:- To determine the surgical approach most suited in our setup and evaluate the results based on the functional and cosmetic outcome especially in the range of motion,the subsequent defromity, if any, and the carrying angle. Setting Orthopaedic surgery, Nishtar Hospital, Multan. Duration Two years, Study design Quasi experimental type of study. Material & Methods Thirty patients. Sampling technique Non-probability technique. Results The age of the patients included in our study ranged from 4-10 years with a mean age of 5.93 years in group A and 6.66 years in group B. Out of 30 patients in group-A and 11 (73.3%) males and 4(26.6%) in group B had fracture on right side where as 12(80%) in group-A and 11(73.3%) in group-B got injured due to fall from height. One (6.66%) patients from group-A and B had superficial wound infection. Pin tract infection was found in 1(6.66%) in group A and 2(13.33%) patients in group-B. Conclusion: This technique was easy to perform and proved to be safe, although hospitalization time was minimum in both groups. So we recommend medial approach for open reduction and internal fixation of all displaced supra-condylar fractures of humerus in children with appropriate indications.

scholarly journals Comparison of conjunctival free autograft and Rotational flap technique in primary pterygium surgery: Visual changes and safety profiles

2021 ◽  
Vol 6 (3) ◽  
pp. 50-55
Author(s):  
Dr. Pawan Chaurasia ◽  
◽  
Dr. Vaishali Chaurasia ◽  
Keyword(s):  
Visual Acuity ◽  
Patient’S Satisfaction ◽  
Conjunctival Autograft ◽  
Flap Technique ◽  
Rotational Flap ◽  
Group A ◽  
Pterygium Surgery ◽  
Pterygium Excision ◽  
Group B ◽  
Visual Changes

Aims and objectives: To evaluate the postoperative symptomatic comfort, visual changes,complication and rate of recurrence in free conjunctival autograft and rotational flap technique inprimary pterygium surgery. Materials & Methods: This prospective study was conducted in 60 eyesof 60 patients, presented with primary progressive nasal pterygium larger than 1mm causingsymptomatic discomfort, astigmatism and cosmetic disfigurement. Patients were divided into twogroups randomly. In group A, patients with pterygium excision with free conjunctival autograft andgroup B, pterygium excision with rotation flap technique were included. Post-operative day 1symptomatic comfort (symptoms and signs), graft stability, corneal clarity and any complicationwere noted. Visual acuity (VA), auto-refracto keratometer measurements and detailedbiomicroscopic examinations, were performed preoperatively and postoperatively at 1month and 3months. Results: Most of the patients in our study were in the middle age group of 40-49 years(41.6%). Out of 60 patients, 35 were males (58.4%) and 25 were females (41.6%). Patients withoutdoor activities had a higher prevalence of pterygium (78.4%). The incidence of pterygium wasmore in the right eye (60%) than left eye (40%). Of the 60 patients, Grade I, II and III pterygiumwas 20%, 56.7% and 23.3% in group A and 16.7%, 63.3% and 20% in group B respectively. Themean symptomatic score was statistically significantly higher for group A for each factor (P<0.05).In the 3rd month, the overall patient’s satisfaction score was significantly higher in group B(P<0.05). Conclusion: Both surgical techniques were equally effective in terms of visual acuity,astigmatism and recurrence. The patient’s satisfaction score was significantly higher in the rotationflap technique group.

scholarly journals To Study the Safety of Multi-dose Topical Anaesthetic Eye Drops One Month after Opening

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Mehr-un-Nisa Irfan Qayyum Malik Muhammad Wasif Irshad
Keyword(s):  
Fungal Growth ◽  
Eye Drops ◽  
Topical Anaesthetic ◽  
Dry Eyes ◽  
Study Results ◽  
Department Of Ophthalmology ◽  
Quasi Experimental ◽  
Organism Growth ◽  
Group A ◽  
Group B

Purpose: To determine the risk of ocular infections due to topical multi-dose anaesthetic eye drops in patients one month after opening the bottle. Study Design: Quasi experimental study. Place and duration of study: Department of Ophthalmology DHQ Teaching Hospital, Gujranwala from 22nd May 2018 to 22nd June 2018. Materials and Methods: In this study topical anaesthetic eye drops containing proparacaine hydrochloride 0.5% as main ingredient and benzalkonium choride as preservative (Alcaine�) were tested daily to see if any bacterial/fungal growth occurs in the bottle containing eye drops or not. Same bottle was used in patients presenting in outdoor and indoor departments. Samples taken from the bottle contents were cultured on different media to see growth of fungi or bacteria. Patients who already had keratitis, conjunctivitis, corneal opacities, thin corneas and having dry eyes which were prone to get infected were excluded from this study. Results: There were 60 patients included in our study and they were divided in two groups. Group A included those who presented in the outdoor department and group B comprised of those admitted for various operative procedures. There were 30 patients in each group. All patients were adults (18-60 years). After 1 month of daily culturing on agar plates, no micro-organism growth was seen in both groups. Conclusion: Topical anaesthetic eye drops can be used safely for 1 month in different patients after opening the bottle without any risk of causing infectious keratitis, conjunctivitis or endophthalmitis. Keywords: Proparacaine, Culture medium, Endophthalmitis.

scholarly journals Complications and Recurrence after Pterygium Excision using Mitomycin C Eye Drops versus Sutureless and Glue Free Conjunctival Autograft: A Prospective Study

2020 ◽  
Author(s):  
Prachi Shukla ◽  
Suman Bhartiya
Keyword(s):  
Mitomycin C ◽  
Recurrence Rate ◽  
Eye Drops ◽  
Conjunctival Autograft ◽  
Group A ◽  
Pterygium Excision ◽  
The Difference ◽  
One Year ◽  
Group B

Introduction: Recurrence is the most common problem with pterygium excision. Various adjunctive methods have been described to decrease the recurrence rate of pterygium. Mitomycin C (MMC) and limbal Conjunctival Autograft (CAG) are most commonly used methods to reduce its recurrence. Aim: To compare the recurrence rate of pterygium and the complications with MMC eyedrops after bare sclera pterygium excision versus sutureless and glue free CAG. Materials and Methods: Total 104 eyes were divided into two groups (A and B) of 52 eyes each. Group A patients underwent bare sclera excision of pterygium followed by 0.01% MMC eye drops BD (twice a day) for five days and Group B patients had sutureless and glue free CAG using oozing blood as tissue adhesive after pterygium excision. The patients were followed-up postoperatively on day 1, day 3, day 7, one month, three months, six months and one year. All the patients were examined for recurrence and complications. Statistical analysis was done by using Statistical Package for the Social Sciences (SPSS) version 16 and student’s t-test was applied for comparison. Results: A total of 104 eyes of 92 patients were divided into two groups (A and B) of 52 each. The mean age of Group A was around 45 year and group B was around 43 years and the difference was statistically insignificant (p>0.05). Total three patients had recurrence in one year of follow-up in group A, out of which first case appeared before the end of 1st month, second before the completion of 3rd month and the third case at the last follow-up. In group B only one case presented with recurrence at 6th month follow-up. The difference between the recurrences in both the groups was statistically insignificant (p>0.05). Short term complications were observed in five patients in group A. One patient had corneal thinning; one had scleral thinning, two patients presented with avascular sclera and one patient with granuloma. In group B, 18 patients with graft retraction, eight with graft oedema, five with sub-conjunctival graft haemorrhage and one with granuloma were observed. All these complications resolved by the time. Long term complications were not observed in any patient of both the groups. Conclusion: This study concluded that the use of MMC eye drops (0.01%) BD or glue free and sutureless CAG after pterygium excision is safe and effective treatment modalities for pterygium.

scholarly journals A comparative study of conjunctival autograft with fibrin glue or glueless sutureless conjunctival autograft after pterygium surgery

2018 ◽  
Vol 6 (2) ◽  
pp. 557
Author(s):  
Kalpna Jain ◽  
J. M. Manoher
Keyword(s):  
Fibrin Glue ◽  
Cost Effective ◽  
P Value ◽  
Conjunctival Autograft ◽  
Group A ◽  
Pterygium Surgery ◽  
Randomized Control ◽  
Group B ◽  
Control Study ◽  
Conjunctival Autografting

Background: Conjunctival autografting after Pterygium excision can be done by fibrin glue or sutures but use of foreign material can cause discomfort and infection. Fibrin glue may cause hypersensitivity reaction and also have risk of viral transmission. To avoid these conjuctival autograft can be applied without suture or glue. Patient’s own blood act as a bioadhesive.Methods: We done a prospective randomized control study of 70 patients, 35 patients allocated in each group. Group A had conjunctival autograft with fibrin glue while group B had conjunctival autografting without glue or sutures.Results: In group A 31 and group B 26 patients had well placed conjunctival autograft while 4 in group A and 9 patients in group B had either displaced or dislodged graft. The results were statistically insignificant with P value of 0.219 and No complication was reported in any patient except recurrence. The 5 patients in group A and 6 in group B had recurrence which is not statistically significant.Conclusions: Graft stability is more with fibrin glue as compare to glueless and sutureless conjunctival autografting but using patients own blood as bioadhesive is safer and cost effective. The rate of recurrence is similar in both the groups.

COMPARISON OF EFFECTIVENESS OF MOBILIZATION AND SELF-EXERCISES IN ADHESIVE CAPSULITIS OF SHOULDER

2018 ◽  
Vol 7 (1) ◽  
pp. 35-41
Author(s):  
Muhammad Usman Khan ◽  
Ghazala Noor Nizami ◽  
Ali Farhad
Keyword(s):  
Pain Intensity ◽  
Adhesive Capsulitis ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
T Test ◽  
P Value ◽  
Group A ◽  
Group B

OBJECTIVE To compare the effectiveness of mobilization and self-exercises in the management of adhesive capsulitis of shoulder STUDY DESIGN Randomized Control Trial SAMPLE SELECTION 30 patients of adhesive capsulitis of shoulder from physiotherapy department of tertiary care hospitals of Karachi were selected through simple random sampling technique. PROCEDURE Treatment was continued for 5 days per week for the period of 3 weeks followed by assessment. Patients were randomly divided into two equal groups. Group A was treated with midrange mobilization while group B performed self-exercises. Both groups received TENS and hot pack prior to the exercises. Mean ± SD, frequencies and percentages were used for descriptive analysis. ROM via goniometry and pain intensity through VAS was analyzed by paired t-test within the groups and by independent t-test between the groups, using SPSS. P-value of less than 0.05 was considered significant. RESULTS 60% were females (n=18) and 40% were males (n=12) with mean age of 50.17±6.37 years. Significant improvement (p-value <0.05) in pain and shoulder ROM was observed among patients of Group A as compared to Group B. Pain intensity was decreased to 1.67 ± 0.62 in group A, whereas ROMs in these patients were also better than other group.

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