scholarly journals Correlation between severity of diabetes mellitus, polyneuropathy and nasal mucociliary clearance

2020 ◽  
Vol 7 (12) ◽  
pp. 726-729
Author(s):  
Mirac Aysen Unsal ◽  
Suphi Bulgurcu
Keyword(s):  
Diabetes Mellitus ◽  
Mucociliary Clearance ◽  
Diabetic Polyneuropathy ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Group 2 ◽  
Nasal Mucociliary Clearance

Objective:  To examine the relationship between the severity of polyneuropathy and nasal mucociliary clearance times in patients with polyneuropathy and investigate how the presence and severity of electrophysiological polyneuropathy might affect mucociliary clearance in patients with diabetes mellitus. Material and Methods: This prospective cross-sectional study was carried out in the Neurol-ogy and Ear, Nose and Throat (ENT) clinics in a tertiary hospital.  The study included three groups of patients with 20 participants in each group (Group 1, patients with diabetic poly-neuropathy; Group 2, patients with non-diabetic polyneuropathy; and Group 3, diabetes melli-tus patients with a normal nerve conduction study) Nasal saccharin test was performed on all patients. Results: There was a statistically significant difference in the duration of nasal mucociliary clearance among the groups (p= 0.001). There was a positive, statistically significant (p = 0.007) correlation between the nasal mucociliary clearance duration and the severity of poly-neuropathy. The nasal mucociliary clearance duration increased with the severity of polyneuropathy. Conclusion: Patients with diabetes mellitus are a special group, and preventable problems should be taken into consideration when examining nasal pathologies. It should be kept in mind that nasal mucociliary clearance dysfunction can be both a cause and a result in management of diabetes mellitus patients, and thus it should be evaluated carefully.

scholarly journals Effect of metformin on blood lipids in patients with diabetes mellitus

2020 ◽  
Vol 13 (2) ◽  
pp. 23-27
Author(s):  
Tahniyah Haq ◽  
Sabah Haq
Keyword(s):  
Diabetes Mellitus ◽  
Blood Lipids ◽  
Plasma Lipid ◽  
Average Dose ◽  
Lipid Levels ◽  
Cross Sectional ◽  
Significant Difference ◽  
Patients With Diabetes ◽  
Group 2 ◽  
Group 1

Background and objectives: Metformin improves macrovascular complications in people with diabetes mellitus (DM). Although the exact mechanism is not known, metformin has beneficial effects on dyslipidaemia. The aim of the study was to find out if there was an effect of metformin on blood lipids in people with diabetes mellitus. Method: This was a cross-sectional study which included 80 patients with diabetes mellitus. They were divided into 2 groups – (a) Group 1: on metformin and (b) Group 2: without metformin medication. None of the patients were on any other anti-diabetic medication. All data were obtained from patients’ medical records. Individual blood lipids and lipid ratios were compared between two groups. Result: Group 1 included 42 patients with a mean HbA1c of 7.58 ± 0.24% taking an average dose of 820.83 ± 60.40 mg/day of metformin. Group 2 consisted of 38 patients with mean HbA1c of 7.58 ± 0.29%. There was no significant difference in individual plasma lipid levels, lipoprotein ratio or frequency of dyslipidaemia between patients taking and not taking metformin (p>0.05). Also, different doses of metformin had no significant effect on the plasma lipid levels. Conclusion: Metformin did not affect the lipid profile of patients with diabetes mellitus. Ibrahim Med. Coll. J. 2019; 13(2): 23-27

scholarly journals Frequency of depression in patients with Type 1 and Type 2 diabetes mellitus.

2020 ◽  
Vol 27 (06) ◽  
pp. 1291-1296
Author(s):  
Zainab Nawaz ◽  
Adil Afridi ◽  
Shakeel Asif ◽  
Asad Tamizzudin Nizami ◽  
Fareed Aslam Minhaas
Keyword(s):  
Diabetes Mellitus ◽  
Severe Depression ◽  
Management Plan ◽  
Cross Sectional Study ◽  
Categorical Variables ◽  
P Value ◽  
Mild Depression ◽  
Cross Sectional ◽  
Significant Difference ◽  
Patients With Diabetes

Objectives: To determine the frequency of depression in patients with diabetes mellitus and comparison of the frequency of depression in patients with diabetes mellitus (type1 & 2). Study Design: Descriptive Cross-Sectional Study. Setting: Diabetic Clinic of Benazir Bhutto Hospital, Rawalpindi. Period: From 6th June - 5th December 2016. Material & Methods: A total of 200 patients with diabetes mellitus were inducted in the study through Diabetic Out Patient Department at Benazir Bhutto Hospital, Rawalpindi. Patients screening was done by using ICD10-criteria &Beck Depressive inventory (depression diagnosis and severity assessment). Designed proforma was used for demographic details and variables. The data was analyzed using SPSS version 16.0. Depression frequency and severity was calculated. Chi Square test was applied depression and categorical variables associations. Results: Frequency of depression in the study sample came out to be 57% (114 out of 200 patients). Results concluded that 26 patients have mild depression (13%), 38 (19%) moderate depression, and 24 (12%) with severe depression. There is no significant difference in frequencies of depression in terms of type of Diabetes mellitus i.e. T1DM vs T2DM (39% vs 61%, P value > 0.05). Monthly income and BMI were factors leading to mental distress. Conclusion: Many of the patients with diabetes have co-morbid depression. Screening and appropriate treatment of depression should be part of the management plan of all patients having diabetes.

scholarly journals The correlation between uremic pruritus and blood lead levels in prevalent hemodialysis patients and its relation to the severity of pruritus using visual analog score

2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Sahar Mahmoud Shawky ◽  
Reeham Abdel Aziz Abdel Hamid ◽  
Lina Essam Khedr
Keyword(s):  
Blood Lead ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Visual Analog Score ◽  
Blood Lead Levels ◽  
Cross Sectional ◽  
Uremic Pruritus ◽  
Significant Difference ◽  
Lead Levels ◽  
Group 2

Abstract Background Pruritus is a common and often distressing symptom in patients with chronic kidney disease. Though the pathogenesis of uremic pruritus remains poorly understood, systemic inflammation has presented itself as one of the possible explanations. High blood lead levels (BLLs) have been noted to be associated with inflammation and poor nutritional status in hemodialysis patients. Our aim is to study the relation between blood lead levels and uremic pruritus. This is a cross-sectional study that enrolled 50 patients; all were on regular hemodialysis 3 times per week for at least 6 months. Patients were divided into 2 groups, group 1 (n =10) with no pruritus and group 2 (n=40) with varying degrees of pruritus. Group 2 was further divided according to intensity of pruritus by visual analog score (VAS) into mild (n=10), moderate (n=20), and severe pruritus (n=10). Results There was a significant difference in serum lead levels and ferritin levels between groups 1 and 2 (p value < 0.01 and < 0.05, respectively). There was a statistically significant difference in serum lead levels in the groups with varying intensity of pruritus, having higher serum lead levels in patients who exhibited severe pruritus (p value < 0.005) Moreover, a statistically significant relation between elevated blood lead levels and the duration of dialysis was observed in this study. Conclusion Uremic pruritus is a multi-factorial phenomenon, and our study showed that blood lead levels in hemodialysis patients might be associated with increased intensity of pruritus.

Sonographic Assessment of Renal Volume in Normotensive Pregnant Women and Women With Pregnancy-Induced Hypertension in Enugu Metropolis

2021 ◽  
pp. 875647932110210
Author(s):  
Idigo Felicitas Ugochinyere ◽  
Nwankwo Sylvia Chiamaka ◽  
Abonyi Everistus Obinna ◽  
Anakwue Angel-Mary Chukwunyelu ◽  
Agbo Julius Amechi
Keyword(s):  
Reference Range ◽  
Interobserver Variability ◽  
Correct Diagnosis ◽  
Negative Relationship ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Renal Volume ◽  
Cross Sectional ◽  
Significant Difference ◽  
Induced Hypertension

Objective: Renal volume (RV) assessment during obstetric sonography is rarely considered in our locality. Understanding the changes in RV in both normotensive pregnant (NP) and pregnancy-induced hypertensive (PIH) women is important in making correct diagnosis regarding pregnancy outcome. This study is aimed at determining the RV in NP and PIH women and correlating RV with fetal gestational age (FGA), body mass index (BMI), and parity in NP women. Materials and Methods: This cross-sectional study involved 450 patients recruited at a Tertiary Hospital. A pilot study was done to determine the interobserver variability in RV measurement. RV was calculated using the following formula: L × W × AP × 0.523. Parity, BMI, and blood pressure were documented, while FGA was calculated as an average of FGAs obtained from the measurements of fetal biometric parameters. Results: Mean RV of PIH women was significantly higher than that of NP women ( P < .05). RV shows a positive significant relationship with BMI and FGA, while it shows a negative relationship with parity in NP ( P < .05). Conclusion: Reference range values of RV were generated for clinical use in our locality, while there is statistically significant difference between RV in NP and PIH women.

Nasal mucociliary clearance in patients with diabetes mellitus

1989 ◽  
Vol 103 (9) ◽  
pp. 853-855 ◽  
Author(s):  
W. L. Yue
Keyword(s):  
Diabetes Mellitus ◽  
Mucociliary Clearance ◽  
Mean Value ◽  
Nasal Disease ◽  
Patients With Diabetes ◽  
History Of ◽  
Insulin Dependent ◽  
Mucociliary Function ◽  
The Mean ◽  
Nasal Mucociliary Clearance

AbstractFifty insulin-dependent diabetics and 50 non-diabetics without a history of nasal disease have been studied for nasal problems including mucociliary function complicated by diabetes mellitus. For the diabetics, the mean value of nasal mucociliary clearance was considerably decreased and this was more often associated with dry noses but increased pH-values, both of which were higher than those for non-diabetics (p<0.05). As suggested in earlier literature, more aggressive nasal moistening therapy must be recommended for those patients presenting with these conditions in the light of systemic diabetic abnormalities.

scholarly journals Association between obesity and depression in patients with diabetes mellitus type 2; a study protocol

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 7 ◽  
Author(s):  
Eduardo De la Cruz-Cano ◽  
Carlos Alfonso Tovilla-Zarate ◽  
Emilio Reyes-Ramos ◽  
Thelma Beatriz Gonzalez-Castro ◽  
Isela Juarez-Castro ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Diabetes Mellitus Type 2 ◽  
Cross Sectional Study ◽  
Diabetes Mellitus Type ◽  
Sectional Study ◽  
Cross Sectional ◽  
The World ◽  
Patients With Diabetes

Background: Diabetes mellitus and depression are highly prevalent conditions throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 diabetes mellitus that present other health problems (such as hypertension and obesity). The aim of this study protocol is to determine if obesity increases the risk for depression in patient with diabetes type 2.Methods: The analysis will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).The studies suitable for inclusion will be assessed by the Newcastle-Ottawa Scale (NOS) to determine their methodological quality. To identify the studies of interest, we will search on PubMed and EBSCO databases. We will use the following keyword combinations: "Diabetes Mellitus type 2 AND obesity AND depression", "depression AND Diabetes Mellitus type 2", "Diabetes Mellitus type 2 AND body mass index cross sectional study", "depression AND obesity cross-sectional study". Causes for exclusion will be publications that studied patients diagnosed with diabetes mellitus type 1; articles that focused on the treatment and complications of diabetes mellitus type 2; publications that have studied other clinical or psychiatric conditions (for instance, seizure disorder or history of schizophrenia, bipolar disorder, psychotic symptoms or dementia).Conclusion: The results of this study will form the basis for a better understanding of the association between obesity and depression in patients with diabetes mellitus type 2, and will allow development of prediction tools and better interventions. It is evident that several modifiable and non-modifiable risk factors play an important role in the pathogenesis of diabetes among population. Currently, evidence for the deleterious effects of diabetes mellitus type 2 are based on cross-sectional or other observational designs. Therefore, this study will have important implications for future research and public health guidance.

scholarly journals Prevalence of serological markers for hepatitis and potential associated factors in patients with diabetes mellitus

2018 ◽  
Vol 26 (0) ◽  
Author(s):  
Clarissa Cordeiro Alves Arrelias ◽  
Fernando Belissimo Rodrigues ◽  
Maria Teresa da Costa Gonçalves Torquato ◽  
Carla Regina de Souza Teixeira ◽  
Flávia Fernanda Luchetti Rodrigues ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Associated Factors ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Blood Collection ◽  
Serological Markers ◽  
Cross Sectional ◽  
Patients With Diabetes

ABSTRACT Objective: to estimate the prevalence of serological markers for hepatitis B and C in patients with diabetes mellitus and analyze potential associated factors. Method: a cross-sectional study with 255 patients with diabetes mellitus. Demographic, clinical, and risk behavior factors for hepatitis B and C were selected. The markers HBsAg, Anti-HBc IgG, Anti-HBc IgM, Anti-HBs, and Anti-HCV were investigated. A questionnaire and venous blood collection and inferential statistical analysis were used. Results: 16.8% of the patients had a total reactive Anti-HBc marker, 8.2% an isolated Anti-HBs, and 75% were non-reactive for all hepatitis B markers. No case of reactive HBsAg was found and 3.3% of the patients had a reactive anti-HCV marker. The prevalence of prior hepatitis B virus infection was directly associated with the time of diabetes mellitus and the prevalence of hepatitis C virus infection was not associated with the investigated variables. The prevalence of hepatitis B and C infection in patients with diabetes mellitus was higher when compared to the national, with values of 16.8% and 3.3%, respectively. Conclusion: the results suggest that patients with diabetes are a population of higher vulnerability to hepatitis B and C, leading to the adoption of preventive measures of their occurrence.

scholarly journals Study of Maternal and Fetal Outcome among Booked and Unbooked Patients at tertiary Hospital

2020 ◽  
Vol 5 (2) ◽  
pp. 1027-1030
Author(s):  
Shanti Sunuwar Subedi ◽  
Rakina Bhansakarya ◽  
Sajjan Kumar Sharma
Keyword(s):  
Sampling Technique ◽  
Secondary Level ◽  
Tertiary Hospital ◽  
Fetal Outcome ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Spontaneous Vaginal Delivery ◽  
Significant Difference ◽  
The Difference

Introduction: To evaluate the maternal and perinatal outcome in booked and unbooked cases. Objectives: To assess the maternal and fetal outcomes in unbooked and booked patients. Methodology: This was a cross-sectional comparative study conducted in the Department of Obstetrics and Gynecology from Augustti2019 to January 2020. Using a convenient sampling technique, 204 samples were taken and cross-sectional study was done. Results: There were total 204 cases in this study;102were booked and 102 were unbooked. In this study, 85(83%) of booked cases were educated up to secondary level as compared toti65 (64%) of unbooked cases. There was no significant difference in Apgar score in 1 and 5 minute between booked and unbooked cases. More babies in the unbooked group were transferred to NICU as compared to the booked group and the difference was significant (9.8%vs 1.9%). Greater proportion of booked cases had spontaneous vaginal delivery (81.3% vs 59.8%) and complications like preterm delivery, anemia, preeclampsia/ eclampsia, complicated labor and puerperal sepsis was also less in the booked group. Conclusions: The study showed that unbooked mothers and their newborns had higher chance of having complications.

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