DEVELOPMENT OF AN AUTOMATED SYSTEM FOR DIAGNOSING EYE DISEASES BASED ON PRODUCTION RULES

Author(s):  
Анастасия Сергеевна Бизюкина ◽  
Юлия Сергеевна Данилова

В статье рассматриваются вопросы диагностики заболеваний органов зрения и его придаточного аппарата. Медико-социальное значение болезней органов зрения и его придаточного аппарата в современных условиях велико и определяется, прежде всего, их крайне высокой частотой среди различных контингентов населения. Так как зрение является для человека важнейшим из всех органов чувств, без которого невозможна полноценная жизнь, необходимо вовремя выявлять различные патологии и применять незамедлительные меры лечения. Одним из средств повышения эффективности диагностики заболеваний глаз является автоматизация обработки диагностических данных с использованием современных технологий, а именно компьютерной системы поддержки принятия решений. Данная статья посвящена разработке автоматизированной системы диагностики заболеваний глаза на основе продукционных правил. Следует отметить, что процесс медицинского офтальмологического исследования занимает значительное время на различного рода лабораторные анализы, инструментальную диагностику, опрос больного или физического исследования. Автоматизированная компьютерная система диагностики глазных заболеваний предназначена для автоматического установления по характерным признакам таких диагнозов как острый конъюнктивит, острый ирит, острый приступ глаукомы и катаракта. Разработанная программа, реализованная в системе визуального объектно-ориентированного программирования С++, представляется пользователям как консультант для автоматизации работы, что позволит повысить эффективность процесса диагностики заболеваний органов зрения и его придаточного аппарата The article deals with the diagnosis of diseases of the organs of vision and its accessory apparatus. The medical and social significance of diseases of the organs of vision and its accessory apparatus in modern conditions is great and is determined, first of all, by their extremely high frequency among various contingents of the population. Since vision is the most important of all sense organs for a person, without which a full life is impossible, it is necessary to identify various pathologies in time and apply immediate treatment measures. One of the means to increase the effectiveness of the diagnosis of eye diseases is the automation of diagnostic data processing using modern technologies, namely a computer decision support system. This article is devoted to the development of an automated system for diagnosing eye diseases based on production rules. It should be noted that the process of medical ophthalmological examination takes considerable time for various kinds of laboratory tests, instrumental diagnostics, patient interview or physical examination. The automated computer system for the diagnosis of eye diseases is designed to automatically establish the characteristic signs of such diagnoses as acute conjunctivitis, acute iritis, acute attack of glaucoma and cataract. The developed program, implemented in the C++ visual object-oriented programming system, is presented to users as a consultant for automating work, which will increase the efficiency of the process of diagnosing diseases of the visual organs and its accessory apparatus

2020 ◽  
pp. 1357633X1989388
Author(s):  
Anne-Sophie Boureau ◽  
Helene Masse ◽  
Guillaume Chapelet ◽  
Laure de Decker ◽  
Pascal Chevalet ◽  
...  

Introduction Population-based studies show a significant increase in the prevalence of visual impairment in older patients. However, older patients and patients with lower Mini-Mental State Examination (MMSE) scores have few ophthalmological assessments. The main objective of our study was to evaluate the feasibility of tele-ophthalmological screening for ophthalmological diseases in older patients referred for cognitive assessment. Methods This monocentric prospective study included patients referred to a memory clinic for cognitive assessment. All patients underwent a geriatric assessment comprising a cognitive assessment associated with tele-ophthalmological screening undertaken by an orthoptist, including undilated retinal photography. The retinal photographs were subsequently sent to an ophthalmologist. We identified patients who were not eligible for ophthalmological assessment, for patients that had to come back due to poor-quality retinal photographs and finally for detected eye diseases. The association between the geriatric variable and newly detected eye diseases was analysed in univariable and multivariable analyses. Results The mean age of the 298 patients included was 83.5 years  ± 5.65; 29.5% were male. The mean MMSE score was 20.8 ± 5.2; 66.3% of patients had a diagnosis of dementia. Eighteen patients (6.0%) were not eligible for ophthalmological examination and 13 patients (4.6%) were asked to come back owing to poor-quality retinal photographs. Forty-one patients (13.7%) had a newly detected eye disease. In multivariable analysis, patients with a lower MMSE had significantly more newly identified eye diseases. Discussion The tele-ophthalmological screening method identified unknown ophthalmological diseases requiring specialised management in this older population with cognitive complaints.


2021 ◽  
Vol 14 (4) ◽  
pp. 22-30
Author(s):  
N. A. Bakunina ◽  
L. N. Kolesnikova ◽  
G. V. Poryadin ◽  
J. M. Salmasi ◽  
L. M. Balashova

Purpose. To study the involvement of vascular and vegetative factors in the pathogenesis of glaucoma attack. Material and methods. 12 patients (24 eyes) aged 49 to 82 — 5 men and 7 women, including 3 patients with acute glaucoma and 9 patients with subacute glaucoma were subjected to an ophthalmological examination that included visometry, tonometry, automated static perimetry, OCT and OCT angiography. They were also tested for heart rate variability (HRV) using a Polar heart rate monitor, and for plasminogen content and products of fibrin/fibrinogen degradation in the tear. For comparison, the contralateral eyes of these patients were examined. Results. In the eyes with an acute glaucoma attack, the vascular network was noticeably weakened, especially in the area of the deep peripapillary vascular plexus at the lamina cribrosa level, and focal capillary loss was observed. The peripapillary density of the deep vascular plexus in the eyes with an acute attack was 33.0 ± 5.6 % (М ± m), which was significantly (p < 0.01) lower as compared to 50.0 ± 4.7 % in the unaffected eyes. This indicator correlated with the thickness of the ganglion cell complex (GCC) (p < 0.01). In unaffected eyes, no correlations were found between these glaucoma-related parameters. A significant amount of fibrin/fibrinogen degradation products was found in the tear of glaucoma patients, which may point to a violation of blood circulation in the optic nerve vessels. It has been established that glaucoma attack occurs with increased activity of sympathetic regulation of blood flow. Conclusion. When monitoring this contingent of patients, it is essential to determine the sympathetic-parasympathetic status of the patient. Taking into account the vascular component of the condition, it is expedient to introduce the necessary additions into its treatment plans


PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0258636
Author(s):  
Ireneusz Balicki ◽  
Małgorzata Goleman ◽  
Agnieszka Balicka

This study aimed to describe and determine the prevalence of ocular abnormalities in Polish Hunting Dogs. The study was conducted with 193 Polish Hunting Dogs: 101 female and 92 male animals, aged between 3 months and 12 years. Ophthalmic examinations were performed using slit lamp biomicroscopy, ophthalmoscopy, and tonometry based on the ophthalmological protocol for the examination of hereditary eye diseases. Spectral-domain optical coherence tomography (SD-OCT) was performed for dogs with sudden acquired retinal degeneration syndrome (SARDS) and progressive retinal atrophy (PRA), while electroretinography was also performed in dogs with SARDS. Five dogs (2.6%) were diagnosed with cataract, iris coloboma in 3 dogs (1.6%), ocular dermoid in 1 dog (0.5%), and retinal dysplasia, distichiasis and entropion in 1 dog (1%). Three dogs (1.6%) were diagnosed with PRA and SARDS occurred in 1 dog. Retinal lesions was observed in 16 dogs (8.3%). The clinical signs of retinopathy observed in Polish Hunting Dogs included discoloration of the tapetal fundus, patchy increased reflectivity in the region of discoloration, focus of hyperpigmentation and an area of tapetal hyper-reflectivity with a pigmented center. SD-OCT performed in the 3 dogs with PRA revealed alteration in the retinal layers, which was most advanced in the non-tapetal fundus. Although SD-OCT revealed retinal layers with normal architecture only in some parts of the dorsal, nasal and temporal regions in dogs with SARDS, areas of disorganized external limiting membrane, myeloid zone, ellipsoid zone, outer photoreceptor segment and interdigitation zone were also observed. Polish Hunting Dogs should undergo periodic ophthalmological examination for the evaluation of other hereditary eye diseases. The prevalence of retinal lesions in Polish Hunting Dogs requires further research.


2021 ◽  
pp. 76-82
Author(s):  
S. O. Samusenko ◽  
I. V. Filatova

The urgency of improving the effectiveness of dacryocystitis treatment is determined by: their stable proportion among eye diseases, a high percentage of post−traumatic, iatrogenic and chronic forms, ability to be a source of dangerous complications and social significance. Existing anatomical and physiological relations and values of rhinogenic factors determine the involvement of otolaryngologists in dacryocystitis treatment. In order to determine the characteristics of the contingent of patients with dacryocystitis, structure of rhinogenic factors, methods of examination, surgical treatment and principles of postoperative management of patients, a study was conducted with 107 patients with chronic disease. The clinical effectiveness in diagnosis and planning of surgical intervention of the combination of endonasal optical rhinoscopy, probing and contrast of the nasolacrimal pathway with triombrast with subsequent radiological and (or) CT examination was determined. It is shown that the correction of endonasal structures should be performed simultaneously with dacryocystorhinostomy. The efficiency of the classical West−Bokstein surgery has been determined, the necessity of an individual approach to its planning has been shown. The main tasks of each stage of the surgery, which significantly affect its outcome, are established. When performed correctly, the effectiveness of "plastic" and "simple" rhinostomy, management of patients with and without stenting is almost the same. It has been proven that the use of radio wave and shaver techniques can greatly simplify the stages of the surgery and improve healing. Based on the obtained results, a conclusion was made about the expediency of involving an otolaryngologist in the consultation of patients with chronic dacryocystitis in each case. The criterion for choosing treatment tactics in favor of endonasal endoscopic dacryocystorhinostomy is the presence of rhinogenic factors of dacryocystitis. Key words: dacryocystitis, endonasal endoscopic dacryocystorhinostomy, rhinogenic factors, stenting, surgical treatment, epiphora, lacrimation.


Author(s):  
Rahime Yilmaz ◽  
Anil Sezgin ◽  
Sefer Kurnaz ◽  
Yunus Ziya Arslan

A program is composed of commands, which runs within a computer or an electronic circuit. Programming is a mathematical methodology to write a program and to encode the algorithm into a notation. It can be classified into two groups such as system and application programming. System programming is a branch of the general programming that is composed of low level instructions which are used to operate and handle computer hardware. Application programming is considered as the improved version of the computer programs which can perform specific tasks. One of the application programming types is the object-oriented programming (OOP) which is about how information is represented in human mind. OOP is useful to provide easy modeling in design and developing real entities. This approach is aimed to model the entities and the relationships existing between them. OOP enables to define the required classes to create the objects and to apply modifications on them. The inherent properties of OOP are modularity, extensibility and reusability. This chapter provides a substantial survey of OOP.


1991 ◽  
Vol 10 (2) ◽  
pp. 111-120 ◽  
Author(s):  
JAKOB NIELSEN ◽  
IDA FREHR ◽  
HANS OLAV NYMAND

2019 ◽  
Vol 16 (2) ◽  
pp. 271-276
Author(s):  
A. A. Ryabtseva ◽  
E. E. Grishina ◽  
O. M. Andruhina ◽  
A. A. Kovrizhkina ◽  
S. G. Sergushev ◽  
...  

This report is devoted to the problem of absence universal databases of patients with different chronic eye diseases and continuity of these patients between medical organizations. On the basis of MONIKI there has was held a prospective, observational cohort study of patients since 2016, with diagnoses: uveal melanoma — the first group of patients, degenerative States of the optic nerve and retina (multiple sclerosis, glaucoma) — the second group, — and vascular retinal diseases (venous occlusion, diabetic retinopathy) — the third group. There were 114 patients — in the first, 68 — in the second, 92 — in the third. There were developed statistically significant parameters of patients examination, adaptation of registers to application and increase of their efficiency continues to be corrected. All patients underwent standard ophthalmological examination, in addition-gonioscopy, ultrasound (ultrasound) in a and b-scan mode, including ultrasound biomicroscopy (UBM), optical coherence tomography (OCT), fluorescence angiography (FAG), computed tomography (CT) and/or magnetic resonance imaging (MRI) of the orbit. According to the indications, patients were examined by related specialists. For each patient group, prior results were obtained. They were late detection, untimely treatment and referral patients to other medical organizations, which proves the need to systematize patients with various pathologies and the subsequent continuity of medical organizations as for the timely detection of the disease, as for adequate and timely treatment not only at the local, but also at the regional or Federal levels. The integration of patients register with various ophthalmic diseases has a priority course in the development of healthcare in the Moscow region. 


Author(s):  
Zoran Ž. Avramović ◽  
Radomir Z. Radojičić ◽  
Saša D. Mirković

The paper presents original object oriented programming system ARS for modelling and simulation queuing systems. Programming system was developed in programming language C++. It establishes connection with intrinsic, but also with other Windows programming packages, in a simple way, through object oriented environment. Basic characteristics and possibilities of programming system, as well as comparative analysis of simulators: mathematical model (analytical solution) - GPSS/H - ARS, on the example of closed queuing network in the paper is given. The significant application for computer performance evaluation is reported.


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