scholarly journals PEQULIARITIES OF MORPHOGENESYS AND TOPOGRAPHY OF INFRAHYOID TRIANGLES IN HUMAN PREFETUSES AND FETUSES

2021 ◽  
Vol 74 (1) ◽  
pp. 102-106
Author(s):  
Olexandr V. Tsyhykalo ◽  
Iryna S. Popova ◽  
Olga Ya. Skrynchuk ◽  
Tetiana D. Dutka-Svarychevska ◽  
Larysa Ya. Fedoniuk
Keyword(s):  
Three Dimensional ◽  
Human Fetuses ◽  
Critical Periods ◽  
Intrauterine Development ◽  
Area Index ◽  
Anatomical Structures ◽  
Common Precursor ◽  
Human Ontogenesis ◽  
Developmental Features ◽  
Omohyoid Muscle

The aim: To investigate morphology and developmental features of anatomical structures in the infrahyoid triangles of human neck during prefetal and fetal periods of human ontogenesis. Materials and methods: We have studied 30 specimens of human prefetuses from 7th till 12th week (16,0-82,0 mm of parieto-coccygeal length (PCL)) and 30 human fetuses aged from 4th till 10th month (84,0-360,0 mm PCL) of intrauterine development by the means of macro-, microscopy, morphometry, three-dimensional remodeling and statistical analyses. Results: We can observe anterior triangle in human fetuses after the time when common precursor muscular mass splits into two: the anterior and posterior portions which will give rise to the sternocleidomastoid and trapezoid muscles accordingly. The area index of the central triangle in human fetuses 4th – 10th month of intrauterine development shows the increasing tendency with the highest rates at 8th–10th months period – 1100-1200 mm2. The angulated course of omohyoid muscle is visible at late prefetal and early fetal periods (3-4th month; 80,0-130,0 PCL) as well as the presence of intermediate tendon. Peaks of the area of sternocleidomastoid region area evaluation was observed in 190,0-210,0 mm PCL and 260,0-270,0 mm PCL human fetuses; 6th and 7,5th months accordingly. Conclusions: The critical periods for the AT and SCM regions should be considered 6th and 8th months of the IUD. Prefetal period shows the presence of AT and border structure for the IH neck – precursor of HB. Fetal period of IUD (4th – 10th months of IUD) should be considered as such that represents an adult-alike morphology of IH neck: presence of IH triangles with fully developed vascular, muscular and fascial content.

scholarly journals Peculiarities of morphogenesis of orbit and organ of vision structures in human fetuses

2021 ◽  
Vol 25 (1(97)) ◽  
pp. 95-102
Author(s):  
A. Tsyhykalo ◽  
N. Kozariichuk ◽  
K. Yakovets ◽  
H. Kulynych
Keyword(s):  
Growth Rates ◽  
Three Dimensional ◽  
Lateral Wall ◽  
Human Fetuses ◽  
Critical Periods ◽  
Facial Skeleton ◽  
Intrauterine Development ◽  
Fetal Period ◽  
Age Related ◽  
Human Ontogenesis

The aim of this work is to elucidate the features of morphogenesis, syntopic and morphometric changes in the structures of the orbit, neurovascular and muscular structures of the organ of vision in the fetal period of human ontogenesis.Material and methods. By means of complex of methods of morphological research (anthropometry, morphometry, microscopy, preparation, three-dimensional computer reconstruction and statistical analysis), 30 specimens of human fetuses of both sexes aged from 4 to 10 months of intrauterine development (IUD) (160.0-460.0 mm parietal-coccygeal length (PCL)) were studied. Computer tomography was used to study 17 human fetuses aged from 4 to 9 months of IUD (180.0-440.0 mm PCL).Results. At the end of the 5th month of IUD, an orbital index is 75%, which is noted in the transformation of the shape of orbit from flattened to rounded due to an increase in its vertical size relative to the horizontal one. We associate this transformation of the orbit with syntopic influence of adjacent regions: the growth of the lateral wall of the nasal cavity, development of the paranasal sinuses, and facial skeleton. At the end of the 5th week of intrauterine development, external eyeball muscles are finally differentiated from the common muscle rudiment. The analysis of changes in morphometric parameters of muscles of the eyeball made it possible to derive mathematical functions, that describe normal dynamics of growth of their length, as well as to reveal critical periods of their development in terms of the rate of changes in their thickness and width.Conclusions1. The development of the organ of vision in the fetal period of human ontogenesis is a complex process due to the coordinated interaction between morphological and morphometric changes in the orbit, eyeball and its muscles, nerves and vessels.2. Critical periods of development of the orbit and its structures is the 6th month of intrauterine development, during which there is an uneven growth rate of the size of the muscles of the eyeball, as well as the size of the orbit.3. At the 6th month of intrauterine development, uneven growth rates of the horizontal size of the orbit relative to the vertical one are observed, as a result of which its shape begins to return to the mesoconchal type characteristic of such prefetuses. Such age-related transformations of shape and size of the orbit are due to the growth of the eyeball, skull and face, which generally determines the shape of the orbit.4. Starting from the 8th month of fetal period of development, structure and topography of the structures of the orbit acquire signs of a definitive condition, the shape of the orbit is finally established, and uniform growth rates of all structures of the organ of vision are observed, except for the growth of the circumference of the orbit at the end of prenatal period of human ontogenesis.

scholarly journals Anatomy of the Human Cervical Spine and Spinal Cord at 20–22 Weeks of Intrauterine Development

2021 ◽  
Vol 10 (1) ◽  
pp. 15-20
Author(s):  
A. Yu. Isengulova ◽  
V. A. Galiakbarova ◽  
T. S. Seredinova ◽  
D. N. Lyashchenko ◽  
E. N. Galeeva
Keyword(s):  
Spinal Cord ◽  
Cervical Spine ◽  
Spinal Column ◽  
Fetal Surgery ◽  
Human Anatomy ◽  
Detailed Knowledge ◽  
Human Fetuses ◽  
Intrauterine Development ◽  
Adjacent Structures ◽  
Human Ontogenesis

Early and timely diagnosis of the spinal column and spinal cord pathologies, their intrauterine and postnatal correction require detailed knowledge of the anatomy and topography of the cervical spine in the fetus. The complex interactions of the cervical spine with the corresponding parts of the spinal cord and adjacent structures require detailed study during the embryonic period of ontogenesis.The aim of the study was to investigate the morphometric and topographic anatomical fetal features of the cervical spine and adjacent structures at 20–22 weeks of the intrauterine development.Material and methods. This study was performed on the sectional material from human fetuses, 20–22 weeks of development (20 human fetuses of both sexes), obtained from the fetal collection of the Department of Human Anatomy, Orenburg State Medical University. A standard set of morphological methods were applied in the study – macromicroscopic preparation, Pirogov method of cuts in three mutually perpendicular planes, production of serial histotopograms with Van Gieson staining, photography, morphometry.Results. It was found that during the studied periods of prenatal ontogenesis, the length of the cervical spine averaged 17.5±1.5 mm. The transverse size of the vertebral body in fetuses of 20–22 weeks of development throughout the cervical spine is of greater importance than the anteroposterior. The transverse and anteroposterior dimensions of the vertebral foramen gradually decrease in the craniocaudal direction. It was also demonstrated that it is necessary to remove the dura mater in order to obtain reliable dimensional characteristics of the spinal cord.Conclusion. Thus, the data obtained on the anatomy and topography of the spinal column and the spinal cord at the 20th – 22nd weeks of the human ontogenesis can serve as the morphological basis of fetal surgery.

scholarly journals Developmental features and predicting airway failure risk in critically ill children with mandibular hypoplasia using 3D computational tomographic analysis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Doo-Hwan Kim ◽  
Eunseo Gwon ◽  
Junheok Ock ◽  
Jong-Woo Choi ◽  
Jee Ho Lee ◽  
...  
Keyword(s):  
Risk Factors ◽  
Difficult Airway ◽  
Hyoid Bone ◽  
Three Dimensional ◽  
Upper Airway ◽  
Critically Ill Children ◽  
Healthy Controls ◽  
Mandibular Hypoplasia ◽  
Tongue Position ◽  
Developmental Features

AbstractIn children with mandibular hypoplasia, airway management is challenging. However, detailed cephalometric assessment data for this population are sparse. The aim of this study was to find risk factors for predicting difficult airways in children with mandibular hypoplasia, and compare upper airway anatomical differences using three-dimensional computed tomography (3D CT) between children with mandibular hypoplasia and demographically matched healthy controls. There were significant discrepancies in relative tongue position (P < 0.01) and anterior distance of the hyoid bone (P < 0.01) between patients with mandibular hypoplasia and healthy controls. All mandibular measures were significantly different between the two groups, except for the height of the ramus of the mandible. After adjusting for age and sex, the anterior distance of hyoid bone and inferior pogonial angle were significantly associated with a difficult airway (P = 0.01 and P = 0.02). Quantitative analysis of upper airway structures revealed significant discrepancies, including relative tongue position, hyoid distance, and mandible measures between patients with mandibular hypoplasia and healthy controls. The anterior distance of the hyoid bone and inferior pogonial angle may be risk factors for a difficult airway in patients with mandibular hypoplasia.

scholarly journals PECULIARITIES OF FORMATION OF THE HARD PALATE FOLDS DURING THE SECOND AND THIRD TRIMESTER OF THE INTRAUTERINE DEVELOPMENT

2018 ◽  
Vol 17 (3) ◽  
pp. 64-68
Author(s):  
A. I. Prodanchuk
Keyword(s):  
Hard Palate ◽  
Basal Membrane ◽  
Third Trimester ◽  
Intrauterine Development ◽  
Fibrous Stroma ◽  
Human Ontogenesis ◽  
The Face ◽  
Mesenchyme Cells ◽  
Restorative Surgery ◽  
Comprehensive Study

A comprehensive study of anatomical-functional peculiarities of the cranial bones promotes implementation of new methods of performing radical and reconstructive-restorative surgery on the face and cranium. Objective: to determine peculiarities of formation of the hard palate folds structure in the fetal and early neonatal periods of human ontogenesis. Materials and methods. The study was conducted on 53 specimens of dead fetuses from 4 to 10 months of development and on 9 specimens of dead neonates by means of macro- and micro-section, preparing histological and topographic-anatomical sections, and morphometry. Formation of the hard palate folds during the second and third trimesters of the intrauterine development was found to consist of the following stages:  epithelial thickening, penetration into the adjacent mesenchyme originating the rudiment of the fold; smoothing of the basal membrane and epithelial outgrowth over the surface with formation of the primary fold; condensation of mesenchyme cells under the fold apex; formation of fibrous stroma inside of the fold which is a peculiar core; epithelial smoothing to even thickness similar to that one embracing the areas between folds with formation of the final fold. At the end of the third trimester of the intrauterine development posterior transverse palatine folds become less marked, some of them disappear, and the anterior ones become more marked, closer and pressed one to another.

scholarly journals Lobectomy for lung cancer with a displaced left B1 + 2 and an anomalous pulmonary vein: a case report

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Shinichi Sakamoto ◽  
Hiromitsu Takizawa ◽  
Naoya Kawakita ◽  
Akira Tangoku
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Pulmonary Vein ◽  
Three Dimensional ◽  
Lower Lobe ◽  
Rare Condition ◽  
3D Ct ◽  
Anatomical Structures ◽  
Case Presentation ◽  
Anomalous Pulmonary Vein

Abstract Background A displaced left B1 + 2 accompanied by an anomalous pulmonary vein is a rare condition involving complex structures. There is a risk of unexpected injuries to bronchi and blood vessels when patients with such anomalies undergo surgery for lung cancer. Case presentation A 59-year-old male with suspected lung cancer in the left lower lobe was scheduled to undergo surgery. Chest computed tomography revealed a displaced B1 + 2 and hyperlobulation between S1 + 2 and S3, while the interlobar fissure between S1 + 2 and S6 was completely fused. Three-dimensional computed tomography (3D-CT) revealed an anomalous V1 + 2 joining the left inferior pulmonary vein and a branch of the V1 + 2 running between S1 + 2 and S6. We performed left lower lobectomy via video-assisted thoracic surgery, while taking care with the abovementioned anatomical structures. The strategy employed in this operation was to preserve V1 + 2 and confirm the locations of B1 + 2 and B6 when dividing the fissure. Conclusion The aim of the surgical procedure performed in this case was to divide the fissure between S1 + 2 and the inferior lobe to reduce the risk of an unexpected bronchial injury. 3D-CT helps surgeons to understand the stereoscopic positional relationships among anatomical structures.

scholarly journals FETAL ANATOMY OF PARATHYROID GLANDS

2020 ◽  
Vol 73 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Lesia Ya. Lopushniak ◽  
Тatiana V. Khmara ◽  
Оleh М. Boichuk ◽  
Mariana A. Ryznychuk ◽  
Leonid V. Shvyhar ◽  
...  
Keyword(s):  
Jugular Vein ◽  
Age Groups ◽  
Parathyroid Glands ◽  
Brachiocephalic Vein ◽  
Human Fetuses ◽  
Crown Rump Length ◽  
Fetal Period ◽  
External Structure ◽  
Human Ontogenesis ◽  
The Right

The aim: To study the forms of anatomical variability of the external structure of the upper and lower parathyroid glands in the fetal period of human ontogenesis. Materials and methods: The study involved 48 specimens of human fetuses with 81,0-375,0 mm of crown-rump length (CRL). The study was conducted by means of macromicroscopic preparation, morphometry and variation statistics method. Results: The age and individual anatomical variability, complex way of development and formation of synotopic embryotropographic correlations of the upper and lower parathyroid glands in the prenatal period of human ontogenesis create numerous prerequisites for the emergence of variants of their external structure and topography in the fetuses of both different and the same age groups. Conclusions: There is a significant anatomical variability of the upper and lower parathyroid glands in 4-10-month-old fetuses, which is manifested by varieties of their shape and topical location. Aplasia of the upper parathyroid glands, which was found in two human fetuses aged 7 months, was due to the fetures of their organogenesis and the formation of syntopy in the embryonic and prefetal periods of their development. Parathyroid glands are mainly supplied with blood by the branches of the inferior thyroid artery. The branches of the upper thyroid artery and the arteries of adjacent organs: larynx, trachea and esophagus are involved in the blood supply. The right and left inferior thyroid veins are tributaries of the corresponding brachiocephalic vein, paired (right and left) superior and middle thyroid veins are those for the internal jugular vein.

Three-dimensional computer-assisted dissection of pancreatic lymphatic anatomy on human fetuses: a step toward automatic image alignment

2018 ◽  
Vol 40 (5) ◽  
pp. 587-597 ◽  
Author(s):  
T. Bardol ◽  
G. Subsol ◽  
M.-J. Perez ◽  
D. Genevieve ◽  
A. Lamouroux ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Image Alignment ◽  
Computer Assisted ◽  
Human Fetuses

Anatomical Variability of Fascial-Muscle Formations of the Thorax in 4-6-Month Human Fetuses

2021 ◽  
Vol 6 (5) ◽  
pp. 134-140
Author(s):  
T. V. Khmara ◽  
◽  
I. I. Okrym ◽  
M. Yu. Leka ◽  
I. D. Kiiun ◽  
...  
Keyword(s):  
Pectoralis Major Muscle ◽  
Three Dimensional ◽  
Spinal Column ◽  
Vertical Direction ◽  
Posterior Wall ◽  
Pectoralis Major ◽  
Human Embryos ◽  
Human Fetuses ◽  
Surgical Interventions ◽  
Rib Cartilage

The development of rational accesses and methods of surgical interventions to the chest walls, muscles and vascular-nerve formations of the chest involves clarifying data on the topography of fascia, superficial and deep muscles of the chest at different stages of human ontogenesis. The purpose of the study. Identification of macromicroscopic structure and topography of fascia and chest muscles in 4-6-month human fetuses. Materials and methods. The study was performed using microscopy of a series of consecutive histological sections of 29 human embryos of 81.0-230.0 mm parietal-coccygeal length, production of three-dimensional reconstruction models and morphometry. Results and discussion. In some early fetuses, and in isolated cases in the same fetus, there is anatomical variability of the pectoralis major muscle, characterized by asymmetry of shape, size and topography of individual parts of the right and left pectoralis major muscles. The underdevelopment of the individual muscle bundles of the sternocostal part of the pectoralis major muscle, hypoplasia of the internal intervertebral muscles, aplasia of the external intercostal membrane, internal intercostal and subcostal muscles, transverse muscles of the chest is described. Conclusion. In human fetuses of 4-6 months old there is anatomical variability of the chest muscles, characterized by bilateral asymmetry, variability of shape, size and topography of both their individual parts and muscle as a whole. In early human fetuses, thoracic fascia is a rather thin structural plate, in the structure of which there is no layering. Intervertebral spaces at the level of rib cartilage are filled with internal intervertebral muscles, the fibers of which near the edges of the thorax have a vertical direction, and from the point of connection of the rib cartilage to the thorax – oblique. In the gap between the external and internal intervertebral muscles of fascia as such is not manifested, but only a small layer of loose fiber is determined, in which the vascular-nerve bundles pass. In the fetuses of 6 months, the endothorаcic fascia on the posterior wall of the chest is somewhat thickened, split into separate plates and forms fascial cases for vascular-nerve formations located near the spinal column

scholarly journals Performance of Cone Beam Computed Tomography Systems in Visualizing the Cortical Plate in 3D Image Reconstruction: An In Vitro Study

2018 ◽  
Vol 12 (1) ◽  
pp. 586-595 ◽  
Author(s):  
Abbas Shokri ◽  
Mohammad Reza Jamalpour ◽  
Amir Eskandarloo ◽  
Mostafa Godiny ◽  
Payam Amini ◽  
...  
Keyword(s):  
Image Reconstruction ◽  
3D Reconstruction ◽  
Cortical Bone ◽  
Three Dimensional ◽  
Cortical Plate ◽  
3D Image ◽  
Bone Thickness ◽  
Anatomical Structures ◽  
3D Image Reconstruction ◽  
Dental Procedures

Introduction: Cortical bone is an important anatomical structure and its thickness needs to be determined prior to many dental procedures to ensure treatment success. Imaging modalities are necessarily used in dentistry for treatment planning and dental procedures. Three-dimensional image reconstruction not only provides visual information but also enables accurate measurement of anatomical structures; thus, it is necessarily required for maxillofacial examination and in case of skeletal problems in this region. Aims: This study aimed to assess the ability of three Cone Beam Computed Tomography (CBCT) systems including Cranex 3D, NewTom 3G and 3D Promax for Three-Dimensional (3D) image reconstruction of the cortical plate with variable thicknesses. Methods: Depending on the cortical bone thickness, samples were evaluated in three groups of ≤ 0. 5 mm, 0.6 -1 mm and 1.1-1.5 mm cortical bone thickness. The CBCT scans were obtained from each sample using three systems, their respective FOVs, and 3D scans were reconstructed using their software programs. Two observers viewed the images twice with a two-week interval. The ability of each system in the 3D reconstruction of different thicknesses of cortical bone was determined based on its visualization on the scans. The data were analyzed using SPSS and Kappa test. Results: The three systems showed the greatest difference in the 3D reconstruction of cortical bone with < 0.5 mm thickness. Cranex 3D with 4×6 cm2 FOV had the highest and 3D Promax with 8×8 cm2 FOV had the lowest efficacy for 3D reconstruction of cortical bone. Cranex 3D with 4×6 cm2 and 6×8 cm2 FOVs and NewTom 3G with 5×5 cm2 and 8×5 cm2 FOVs showed significantly higher efficacy for 3D reconstruction of cortical bone with 0.6-1mm thickness while 3D Promax followed by NewTom 3G with 8×8 cm2 FOV had the lowest efficacy for this purpose. Conclusion: Most CBCT systems have high efficacy for 3D image reconstruction of cortical bone with thicknesses over 1 mm while they have poor efficacy for image reconstruction of cortical bone with less than 0.5 mm thickness. Thus, for accurate visualization of anatomical structures on CBCT scans, systems with smaller FOVs and consequently smaller voxel size are preferred.

scholarly journals A Concise Paradigm on Radical Hysterectomy: The Comprehensive Anatomy of Parametrium, Paracolpium and the Pelvic Autonomic Nerve System and Its Surgical Implication

Cancers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1839 ◽  
Author(s):  
Mustafa Zelal Muallem ◽  
Thomas Jöns ◽  
Nadja Seidel ◽  
Jalid Sehouli ◽  
Yasser Diab ◽  
...  
Keyword(s):  
Radical Hysterectomy ◽  
Three Dimensional ◽  
Figo Stage ◽  
Autonomic Nerve ◽  
Nerve Sparing ◽  
Anatomical Structures ◽  
Pelvic Autonomic Nerve ◽  
Direct Infiltration ◽  
Autonomic Nerve System ◽  
Nerve System

The current understanding of radical hysterectomy is more centered on the uterus and little is discussed regarding the resection of the vaginal cuff and the paracolpium as an essential part of this procedure. The anatomic dissections of two fresh and 17 formalin-fixed female pelvis cadavers were utilized to understand and decipher the anatomy of the pelvic autonomic nerve system (PANS) and its connections to the surrounding anatomical structures, especially the paracolpium. The study mandates the recognition of the three-dimensional (3D) anatomic template of the parametrium and paracolpium and provides herewith an enhanced scope during a nerve-sparing radical hysterectomy procedure by precise description of the paracolpium and its close anatomical relationships to the components of the PANS. This enables the medical fraternity to distinguish between direct infiltration of the paracolpium, where the nerve sparing technique is no longer possible, and the affected lymph node in the paracolpium, where nerve sparing is still an option. This study gives rise to a tailored surgical option that allows for abandoning the resection of the paracolpium by FIGO stage IB1, where less than 2 cm vaginal vault resection is demanded.

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