scholarly journals STATE OF CUTANEOUS MICROCIRCULATION IN PATIENTS WITH OBESITY

2021 ◽  
Vol 74 (9) ◽  
pp. 2039-2043
Author(s):  
Iana O. Andreieva ◽  
Olha I. Riznyk ◽  
Sergii P. Myrnyi ◽  
Nikolai N. Surmylo
Keyword(s):  
Vascular Pathology ◽  
Control Group ◽  
Class Iii ◽  
Doppler Flowmetry ◽  
Cutaneous Microcirculation ◽  
Class Iii Obesity ◽  
Biological Tests ◽  
Normal Body Weight ◽  
And Gender ◽  
Cardio Vascular

The aim: To determine the influence of obesity on cutaneous microcirculation in patients with different stages of obesity and without cardio-vascular pathologies. Materials and methods: The 67 eligible patients with obesity were enrolled into the main group in this research. 20 healthy patients with normal body weight were included in the control group in this study. The mean age and gender were similar among the groups. Each patient underwent a clinical evaluation during the consultation, biological tests, electrocardiogram, Laser Doppler flowmetry. Results: There was a significant decrease in IM and σ in patients with class II obesity and class III obesity compared with control group. IV was decreased in all groups, but the significant differences were recorded only among patients with obesity and not among overweight patients. During wavelet analysis a significant decrease of the AmaxE was detected in all 4 groups (by 14,7%, 37,7%, 52,4%, 57,4% respectively, P < 0,05). The most significant changes were recorded in the heart spectrum (AmaxC). Conclusions: Overweight patients and patients with obesity without cardio-vascular pathology have initial manifestations of microcirculatory disorders, which deteriorate with an increase of BMI. Changes in microcirculation in patients with obesity characterized by the significant decrease of microvessels perfusion, decreasing endothelial and increasing heart specter modulations. Only high BMI was found to be associated with impaired microcirculation endothelial function (AmaxE B=0.446, 95% CI [0,15, 0,92]) according to the results of regression analysis.

scholarly journals Influence of intentional ankylosis of deciduous canines to reinforce the anchorage for maxillary protraction

2013 ◽  
Vol 18 (1) ◽  
pp. 94-102 ◽  
Author(s):  
Luís Fernando Castaldi Tocci ◽  
Omar Gabriel da Silva Filho ◽  
Acácio Fuziy ◽  
José Roberto Pereira Lauris
Keyword(s):  
Mixed Dentition ◽  
Control Group ◽  
Class Iii ◽  
Maxillary Expansion ◽  
Significant Treatment ◽  
Maxillary Protraction ◽  
Lateral Cephalograms ◽  
Treatment Changes ◽  
And Gender ◽  
Cephalometric Study

INTRODUCTION: This retrospective cephalometric study analyzed the influence of intentional ankylosis of deciduous canines in patients with Class III malocclusion and anterior crossbite, in the deciduous and early mixed dentition stages, treated by orthopedic maxillary expansion followed by maxillary protraction. METHODS: Lateral cephalograms of 40 patients were used, divided in 2 groups paired for age and gender. The Ankylosis Group was composed of 20 patients (10 boys and 10 girls) treated with induced ankylosis and presenting initial and final mean ages of 7 years 4 months and 8 years 3 months, respectively, with a mean period of maxillary protraction of 11 months. The Control Group comprised 20 patients (10 boys and 10 girls) treated without induced ankylosis, with initial and final mean ages of 7 years 8 months and 8 years 7 months, respectively, with a mean period of maxillary protraction of 11 months. Two-way analysis of variance and covariance analysis were applied to compare the initial and final cephalometric variables and the treatment changes between groups. RESULTS: According to the results, the variables evidencing the significant treatment changes between groups confirmed that the intentional ankylosis enhanced the sagittal response of the apical bases (Pg-NPerp) and increased the facial convexity angles (NAP and ANB). CONCLUSIONS: The protocol involving intentional ankylosis of deciduous canines enhanced the sagittal response of the apical bases.

scholarly journals A comparison of two different techniques for early correction of Class III malocclusion

2011 ◽  
Vol 82 (1) ◽  
pp. 96-101 ◽  
Author(s):  
J. Seehra ◽  
P. S. Fleming ◽  
N. Mandall ◽  
A. T. DiBiase
Keyword(s):  
Linear Regression Analysis ◽  
Face Mask ◽  
Maxillary Incisor ◽  
Control Group ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Mandibular Incisor ◽  
Lateral Cephalograms ◽  
And Gender ◽  
Retrospective Comparative Study

Abstract Objective: To compare the effectiveness of Reverse Twin-Block therapy (RTB) and protraction face mask treatment (PFM) with respect to an untreated control in the correction of developing Class III malocclusion. Materials and Methods: A retrospective comparative study of subjects treated cases with either PFM (n  =  9) or RTB (n  =  13) and untreated matched controls (n  =  10) was performed. Both the PFM and control group samples were derived from a previously conducted clinical trial, and the RTB group was formed of consecutively treated cases. The main outcome variables assessed were skeletal and dental changes. Lateral cephalograms were taken at the start and end of treatment or during the observation period. Analysis of variance was used to compare changes in cephalometric variables arising during the study period in the lateral group. Linear regression analysis and an unpaired t-test were used to determine the impacts of treatment duration and gender, respectively. Results: Significantly greater skeletal changes arose with PFM therapy than with RTB therapy or in the control group (SNA, SNB, and ANB; P &lt; .001). The dentoalveolar effects of RTB therapy exceeded those of PFM treatment, with significantly more maxillary incisor proclination (P &lt; .001) and mandibular incisor retroclination (P &lt; .006) arising with treatment. Conclusions: Both appliances are capable of correction of Class III dental relationships; however, the relative skeletal and dental contributions differ. Skeletal effects, chiefly anterior maxillary translation, predominated with PFM therapy. The RTB appliance induced Class III correction, primarily as a result of dentoalveolar effects.

scholarly journals CLINICAL FEATURES OF GASTROINTESTINAL ULCERATIVE BLEEDING IN ELDERLY PATIENTS COMPLICATED BY CARDIO-VASCULAR PATHOLOGY

2021 ◽  
Vol 74 (2) ◽  
pp. 202-206
Author(s):  
Mykola V. Trofimov ◽  
Valerii P. Kryshen ◽  
Valentyna Y. Kudryavtseva ◽  
Alla V. Chukhriienko ◽  
Pavlo V. Lyashchenko ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Standard Therapy ◽  
Vascular System ◽  
Palliative Surgery ◽  
Vascular Pathology ◽  
Control Group ◽  
Surgical Interventions ◽  
Active Hemorrhage ◽  
Cardio Vascular ◽  
High Level

The aim: To determine clinical and endoscopical features of gastroduodenal hemorrhages in elderly patients with concomitant cardio-vascular pathology in a way by studying, main indicators of the immune system for drawing up further tactics. Material and methods: The study included 609 patients with ulcerative gastroduodenal bleeding, complicated by cardio-vascular system pathology in 2017-2019 years. The observed patients were distributed into the groups: I – patients, who received treatment according to the standard system of cardiovascular pathology treatment (n=541), II – “double” therapy (n=68). Control group consists of 20 relatively healthy patients were similar to the research group. Results: Blood lost of a big amount and massive blood lost were noticed in 113 (18.56%±1.58) and 121 (19.87%±1.62) patients respectively. Active bleeding (F I) was revealed in 38 patients (6.24%±0.98), a high risk of hemorrhage relapse was determined in 486 patients (79.80%±1.63). Signs of recent hemorrhage were absent in 85 patients (13.96%±1.40). A high level of pro-inflammatory cytokines IL-6, TNF-α and a low activity of the anti-inflammatory mediator IL-10 define the process activity, their long-term circulation in patients with ulcerative hemorrhages of the gastro-intestinal tract are associated with unfavorable prognosis. In 5 cases conditionally-radical surgical interventions were performed. Palliative surgery – 3 patients (р>0.05). Conclusions: The patients of second group (“double therapy”) with big and massive blood loss was 2.7 times higher than similar indices in patients of the first group (standard therapy). The patients who received “double therapy” had 3.3 times more active hemorrhage percentage than the patients who received standard therapy (р<0.05).

scholarly journals Mass-normalized internal mechanical work in walking is not impaired in adults with class III obesity

2020 ◽  
Vol 129 (1) ◽  
pp. 194-203
Author(s):  
Aitor Fernández Menéndez ◽  
Barbara Uva ◽  
Lucie Favre ◽  
Didier Hans ◽  
Fabio Borrani ◽  
...  
Keyword(s):  
Body Weight ◽  
Energy Cost ◽  
Center Of Mass ◽  
Mechanical Work ◽  
Similar Amount ◽  
Class Iii ◽  
Obese Adults ◽  
Lower Efficiency ◽  
Class Iii Obesity ◽  
Normal Body Weight

It has been suggested that internal mechanical work (i.e., the work required to move the limbs with respect to the center of mass, Wint) may be responsible for the higher net cost of walking in obese adults, but this variable has not yet been studied in individuals with obesity. The main finding of the present study is that individuals with class III obesity exhibit a similar amount of mass-normalized Wint to that of adults with a normal body weight, suggesting that body mass-relative Wint is not affected by obesity and is not responsible for the higher energy cost and the lower efficiency of walking in this population.

scholarly journals Bone-anchored maxillary protraction in unilateral cleft lip and palate: a cephalometric appraisal

2019 ◽  
Vol 41 (5) ◽  
pp. 537-543 ◽  
Author(s):  
Renato Faco ◽  
Marilia Yatabe ◽  
Lucia H S Cevidanes ◽  
Hilde Timmerman ◽  
Hugo J De Clerck ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Alveolar Bone ◽  
Occlusal Plane ◽  
Control Group ◽  
Class Iii ◽  
Maxillary Protraction ◽  
Alveolar Bone Grafting ◽  
T1 And T2 ◽  
And Gender

Abstract Objectives The aim of this study was to evaluate the cephalometric outcome of bone- anchored maxillary protraction (BAMP) in individuals with unilateral complete cleft lip and palate (UCLP). Material and methods The experimental group (EG) comprised 23 individuals (17 males and 6 females) with UCLP and a mean age of 11.7 years. At least 6 months after secondary alveolar bone grafting, Bollard miniplates were installed in the posterior region of the maxilla and in the anterior region of the mandible. Class III elastics were recommended to be worn for 24 hours/day for a mean time of 18 months. Cone beam computed tomography (CBCT) was obtained before (T1) and after treatment (T2). The control group (CG) consisted of 23 individuals with UCLP matched by initial age and gender with the EG and without any orthopaedic or surgical intervention performed between T1 and T2. The interval between T1 and T2 observations was 18 months for both groups. Twenty-one cephalometric variables were analysed. Intra- and intergroup comparisons were performed using paired and independent t-tests, respectively (P &lt; 0.05). Results BAMP caused a greater maxillary protrusion (SNA) and a greater decrease of Class III maxillomandibular discrepancy (ANB and Wits appraisal) compared with the CG. BAMP also caused a counterclockwise rotation of the occlusal plane (Occ Plane to FH) and an improvement in the molar relationship compared with controls. Conclusions BAMP therapy demonstrated a significant orthopaedic maxillary protraction and an improvement in the Class III skeletal pattern in UCLP.

scholarly journals Visceral Adiposity Is an Independent Determinant of Hypercoagulability as Measured by Thrombin Generation in Morbid Obesity

TH Open ◽  
2017 ◽  
Vol 01 (02) ◽  
pp. e146-e154 ◽  
Author(s):  
P. Chitongo ◽  
L. Roberts ◽  
L. Yang ◽  
R. Patel ◽  
R. Lyall ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Thrombin Generation ◽  
Fat Distribution ◽  
Lag Time ◽  
Visceral Adiposity ◽  
Control Group ◽  
Class Iii ◽  
College Hospital ◽  
Class Iii Obesity ◽  
Independent Determinant

Introduction Increased visceral adipose tissue (VAT) has been shown to be associated with the development of insulin resistance, type 2 diabetes, stroke, and ischemic heart disease. It remains unknown whether fat distribution impacts on coagulation markers and/or the risk of venous thrombosis. This study evaluates markers of hypercoagulability in class III obesity (body mass index [BMI] >40 kg/m2) compared with nonobese controls. We further investigated whether hypercoagulability was influenced by VAT, metabolic syndrome, and metabolic markers, including adiponectin. Patients and Methods Ninety patients were recruited from the obesity clinic at King's College Hospital from November 2009 to December 2011. The inclusion criteria were class III obesity (BMI ≥40 kg/m2) and age 18 to 65 years. A control group (healthy ambulatory participants, with a BMI < 30 kg/m2) was recruited from volunteers responding to advertisement. Abdominal VAT and subcutaneous adipose tissue surface areas were determined by evaluation of a single-slice CT at spinal vertebra L4. Results Thrombin generation revealed a significantly increased peak and endogenous thrombin potential in patients compared with controls. Lag time and time to peak (ttP) were also significantly prolonged in patients. VAT was found to have the strongest association with thrombin generation parameters: lag time (β = 0.378; p < 0.001), peak thrombin (0.378; p = 0.04), and ttP (β = 0.373; p = 0.001). BMI was found to be a predictor for lag time only (β = 0.313; p = 0.003). SAT was not associated with any of the thrombin generation parameters (data not shown). VAT was found to be an independent determinant of peak thrombin, lag time, and ttP. The study suggests not only fat mass but also fat distribution, particularly visceral adiposity, mediates hypercoagulability in obesity.

The response of skin perfusion and of rheological and immunological variables to intravenous prostanoid administration in Raynaud’s phenomenon secondary to collagenosis

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Plasma Viscosity ◽  
Laser Doppler ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Long Term Effects ◽  
Doppler Flowmetry

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.

HUBUNGAN TUNGAU DEBU RUMAH, PAPARAN ASAP ROKOK DAN RIWAYAT PENYAKIT KELUARGA TERHADAP KEJADIAN ASMA BRONKIAL PADA ANAK USIA 5 – 10 TAHUN DI WILAYAH KERJA PUSKESMAS LEMPAKE KOTA SAMARINDA TAHUN 2016

2018 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
Sri Evi New Yearsi Pangadongan ◽  
Agustina Rahyu ◽  
Selvy Pasulu
Keyword(s):  
Cigarette Smoke ◽  
Bronchial Asthma ◽  
Sampling Technique ◽  
Total Sample ◽  
Control Group ◽  
Case Group ◽  
Chi Square ◽  
History Of ◽  
Weather Changes ◽  
And Gender

Bronchial Asthma generally starts from childhood which is condition where respiration channel experiences constriction because of hyperactivity with some specific stimulation which cause inflammation. Some risk factors are smoking exposure of cigarette smoke, weather changes, mite on house dirt, pet and history of family sickness. The purpose of this research is to know Relation of mite on house dirt, exposure of cigarette smoke  and history of family sickness with bronchial asthma incident to child 5 – 10  years old on working area of Puskesmas Lempake Samarinda City in 2016. Method which used was analytic survey with Case Control approaching. The total sample was 36 children which consisted of 18 case group and 18 control group with matching by using age and gender which submitted with Purposive Sampling technique. Data Analysis used Chi Square with wrong degree α = 0,005. The result showed that there was relation of mite of house dirt (p = 0,006), history of family sickness (p = 0,001) and no relation with exposure of cigarette smoke (p = 0,370) with bronchial asthma incident to child 5 – 10 years old on working area of Puskesmas Lempake Samarinda City in 2016.

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