scholarly journals CLINICAL FEATURES OF GASTROINTESTINAL ULCERATIVE BLEEDING IN ELDERLY PATIENTS COMPLICATED BY CARDIO-VASCULAR PATHOLOGY

2021 ◽  
Vol 74 (2) ◽  
pp. 202-206
Author(s):  
Mykola V. Trofimov ◽  
Valerii P. Kryshen ◽  
Valentyna Y. Kudryavtseva ◽  
Alla V. Chukhriienko ◽  
Pavlo V. Lyashchenko ◽  
...  
Keyword(s):  
Elderly Patients ◽  
Standard Therapy ◽  
Vascular System ◽  
Palliative Surgery ◽  
Vascular Pathology ◽  
Control Group ◽  
Surgical Interventions ◽  
Active Hemorrhage ◽  
Cardio Vascular ◽  
High Level

The aim: To determine clinical and endoscopical features of gastroduodenal hemorrhages in elderly patients with concomitant cardio-vascular pathology in a way by studying, main indicators of the immune system for drawing up further tactics. Material and methods: The study included 609 patients with ulcerative gastroduodenal bleeding, complicated by cardio-vascular system pathology in 2017-2019 years. The observed patients were distributed into the groups: I – patients, who received treatment according to the standard system of cardiovascular pathology treatment (n=541), II – “double” therapy (n=68). Control group consists of 20 relatively healthy patients were similar to the research group. Results: Blood lost of a big amount and massive blood lost were noticed in 113 (18.56%±1.58) and 121 (19.87%±1.62) patients respectively. Active bleeding (F I) was revealed in 38 patients (6.24%±0.98), a high risk of hemorrhage relapse was determined in 486 patients (79.80%±1.63). Signs of recent hemorrhage were absent in 85 patients (13.96%±1.40). A high level of pro-inflammatory cytokines IL-6, TNF-α and a low activity of the anti-inflammatory mediator IL-10 define the process activity, their long-term circulation in patients with ulcerative hemorrhages of the gastro-intestinal tract are associated with unfavorable prognosis. In 5 cases conditionally-radical surgical interventions were performed. Palliative surgery – 3 patients (р>0.05). Conclusions: The patients of second group (“double therapy”) with big and massive blood loss was 2.7 times higher than similar indices in patients of the first group (standard therapy). The patients who received “double therapy” had 3.3 times more active hemorrhage percentage than the patients who received standard therapy (р<0.05).

scholarly journals The Influence of Respiratory Component on Satisfaction with Physical Therapy after Cardiosurgical Interventions

2021 ◽  
Vol 6 (4) ◽  
pp. 142-148
Author(s):  
V. V. Vitomskyi ◽  
◽  
Keyword(s):  
Physical Therapy ◽  
Physical Therapist ◽  
Control Group ◽  
Surgical Interventions ◽  
Level Of Satisfaction ◽  
Number Of Cycles ◽  
High Level ◽  
Previous Group ◽  
Incentive Spirometry ◽  
Positive Expiratory Pressure

The purpose of the study was to investigate the effect of additional respiratory physical therapy on the level of satisfaction with physical therapy among patients after cardiac surgery. Materials and methods. The study involved 150 patients. The patients were randomly divided into three groups: control (respiratory physical therapy was limited to cough), group of incentive spirometry (in classes with a physical therapist patients performed additional 3 approaches of 10 breaths through the simulator; they received recommendations for hourly performance of a similar number of cycles of exercise), a group of patients who received additional respiratory physical therapy with positive expiratory pressure in the form of exhalation into a bottle of water through a tube (number of repetitions and recommendations are similar to those received by the previous group). All groups underwent the same protocol of mobilization and use of therapeutic physical exercises in the procedure of therapeutic gymnastics. Performing exercises with breathing simulators began on the first postoperative day. Results and discussion. A questionnaire (17 questions) was used to assess the satisfaction with physical therapy. The survey was conducted on the seventh postoperative day. The answers were distributed on a 5-point Likert scale from 1 point to 5 points. The key preoperative indicators and time indicators of surgical interventions of the examined groups did not differ significantly. Analysis of satisfaction with physical therapy revealed a high level in all items of the questionnaire. Statistical differences between the groups were found in only three items of the questionnaire, but they were not related to either the use of equipment or diligence in treatment or the content of physical therapy. The overall score of the questionnaire did not differ in groups according to the Kraskel-Wallis criterion, and Me indicators (25%; 75%) were in the control group – 81 (77; 85) points, in the group of stimulating spirometry – 81 (72; 85) points in the group with positive expiratory pressure – 79 (73; 84) points (χ2 = 4.560; p = 0.102). Conclusion. Additional respiratory physical therapy did not affect the overall satisfaction rate and results of most items of the questionnaire. The differences found in the three items did not indicate any effect of the use of respiratory physical therapy on the level of satisfaction, as higher scores in these items were in the control group. All items in the questionnaire received high scores

scholarly journals STATE OF CUTANEOUS MICROCIRCULATION IN PATIENTS WITH OBESITY

2021 ◽  
Vol 74 (9) ◽  
pp. 2039-2043
Author(s):  
Iana O. Andreieva ◽  
Olha I. Riznyk ◽  
Sergii P. Myrnyi ◽  
Nikolai N. Surmylo
Keyword(s):  
Vascular Pathology ◽  
Control Group ◽  
Class Iii ◽  
Doppler Flowmetry ◽  
Cutaneous Microcirculation ◽  
Class Iii Obesity ◽  
Biological Tests ◽  
Normal Body Weight ◽  
And Gender ◽  
Cardio Vascular

The aim: To determine the influence of obesity on cutaneous microcirculation in patients with different stages of obesity and without cardio-vascular pathologies. Materials and methods: The 67 eligible patients with obesity were enrolled into the main group in this research. 20 healthy patients with normal body weight were included in the control group in this study. The mean age and gender were similar among the groups. Each patient underwent a clinical evaluation during the consultation, biological tests, electrocardiogram, Laser Doppler flowmetry. Results: There was a significant decrease in IM and σ in patients with class II obesity and class III obesity compared with control group. IV was decreased in all groups, but the significant differences were recorded only among patients with obesity and not among overweight patients. During wavelet analysis a significant decrease of the AmaxE was detected in all 4 groups (by 14,7%, 37,7%, 52,4%, 57,4% respectively, P < 0,05). The most significant changes were recorded in the heart spectrum (AmaxC). Conclusions: Overweight patients and patients with obesity without cardio-vascular pathology have initial manifestations of microcirculatory disorders, which deteriorate with an increase of BMI. Changes in microcirculation in patients with obesity characterized by the significant decrease of microvessels perfusion, decreasing endothelial and increasing heart specter modulations. Only high BMI was found to be associated with impaired microcirculation endothelial function (AmaxE B=0.446, 95% CI [0,15, 0,92]) according to the results of regression analysis.

scholarly journals IMPROVING THE TRAINING PROCESS OF 16–17-YEAR-OLD BIATHLETES BY MEANS OF HYPOXIC-HYPERCAPNIC EXPOSURES AND CONTROL OF CHANGES IN THE PREMORBID CONDITION OF THE CARDIOVASCULAR SYSTEM IN THE BASIC STAGE OF SPORTS PREPARATION

2020 ◽  
Vol 20 (2) ◽  
pp. 14-21
Author(s):  
D Maleev ◽  
E Vinogradov ◽  
A Isaev ◽  
V Khodkevich
Keyword(s):  
Cardiovascular System ◽  
Vascular System ◽  
Diagnostic System ◽  
Training System ◽  
Functional Abilities ◽  
Basic Stage ◽  
General Training ◽  
Cardio Vascular ◽  
High Level ◽  
And Control

Aim. The article deals with theoretical and experimental substantiation of the effectiveness of basic and ergogenic (hypoxic-hypercapnic exposures) aids in the preparation of 16–17-year-old biathletes. Materials and methods. The study involved two groups of 16–17-year-old biathletes. All athletes underwent an in-depth medical examination at the beginning of the experiment. Throughout the study, their functional status was assessed by the premorbid index of the cardio-vascular system obtained with the CardioSoft diagnostic system (USA). Results. Hypoxic-hypercapnic exposures in sports training along with the general training program aimed at deve­loping local-regional muscle endurance is a promising approach that can ensure a high level of functional abilities in athletes and improve their sports results. Conclusion. The results of the study contribute to the improvement of the training system for 16-17-year-old biathletes at the basic stage of sports preparation. The study proves that the innovative method proposed is effective for controlling the premorbid state of the cardiovascular system in athletes.

Changes of State of Cardio-Vascular System in People with Different Levels of Meteosensitivity

2017 ◽  
Vol 2 (2) ◽  
pp. 66-70
Author(s):  
N. A. Vaschuk ◽  
◽  
M. U. Prudenko ◽  
N. S. Hloba ◽  
A. A. Kurbel
Keyword(s):  
Vascular System ◽  
Cardio Vascular ◽  
Different Levels ◽  
Changes Of State

ANTICYTOKINE ACTIVITY OF THE PROTOZOA BLASTOCYSTIS SPP

2020 ◽  
pp. 44-48
Author(s):  
Bugero N.V. ◽  
Ilyina N.A. ◽  
Aleksandrova S.M.
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Ulcer Disease ◽  
Cytokine Balance ◽  
High Prevalence ◽  
Blastocystis Spp ◽  
High Level ◽  
Eukaryotic Organisms ◽  
High Degree

In addition to the classical pathogens, which are well understood and well identified, new pathogens with the potential to spread epidemiologically are being identified. Some of these little-known organisms are the simplest Blastocystis spp. blastocystostosis. The clinical significance of Blastocystis spp. and its pathogenicity are still under discussion. This parasite belongs to a group of single-celled eukaryotic organisms living in the colon of the human intestine. Blastocystis spp. is known to be found both in people with reduced immune status and in individuals without any clinical manifestation. It has been established that a sufficiently high degree of invasiveness is observed in persons with gastrointestinal tract diseases, dermatosis, allergic reactions, in patients with carriers of the human immunodeficiency virus, etc. Possessing persistence factors, protozoa blastocysts contribute to the inactivation of host defensive mechanisms, providing a stable anthogonistic effect. In recent years, many works have been devoted to the characteristics of the persistent properties of Blastocystis spr., however, individual properties of blastocysts, in particular, anticytokine activity (ACA), have not yet been studied. In this regard, the work studied the anticytokine activity of microorganisms isolated from healthy subjects and patients with gastrointestinal tract diseases. A high prevalence of the studied characteristic in the subjects was shown. The expression of anticytokine activity in the obtained isolates of blastocysts was the highest in the group of persons with gastric ulcer disease, which decreased in the order of duodenal ulcer, chronic cholecystitis, chronic gastritis, etc. The data obtained in this work on the high level of ACA expression in blastocyst isolates obtained from individuals with gastrointestinal diseases as compared with the control group enables to conclude that their exometabolites may influence the local cytokine balance [1], which supports the inflammatory process.

OPERATIONS FOR ANEURISM OF THE ABDOMINAL AORTIC DEPARTMENT - RESECTION WITH THE FOLLOWING PROSTHETICS AND ENDOPROSTHETICS: A COMPARATIVE ANALYSIS OF COMPLICATIONS

2020 ◽  
pp. 43-49
Author(s):  
Андрей Анатольевич Иванов ◽  
Александр Иванович Жданов ◽  
Максим Сергеевич Шевелин ◽  
Александр Сергеевич Брежнев
Keyword(s):  
Comparative Analysis ◽  
Postoperative Complications ◽  
Statistical Significance ◽  
Aortic Aneurysms ◽  
Surgical Interventions ◽  
Vein Thrombosis ◽  
Scientific Hypothesis ◽  
Abdominal Aortic ◽  
Life Threatening ◽  
High Level

В статье представлены данные оригинального исследования по улучшению хирургического лечения аневризм брюшного отдела аорты. С этой целью произведен сравнительный анализ двух альтернативных друг другу операций: 1) резекции аневризмы с последующим протезированием аорты; 2) эндопротезирования аорты. Сформулировано научное предположение о том, что замена «классических» операций резекции аневризмы на «альтернативные» операции эндопротезирования приведет к принципиальному снижению уровня послеоперационных осложнений. В независимых группах пациентов с использованием сравниваемых хирургических вмешательств произведена точная качественная и количественная оценка послеоперационных осложнений: нетромботических - кардиальных, пульмональных, ренальных и тромботических - тромбозов глубоких вен и тромбозов браншей протеза. После реализации исследования было установлено, что замена «классических» операций на «альтернативные» достоверно приводит к принципиальному снижению уровня наиболее жизнеопасных осложнений - кардиальных (острых форм ишемической болезни сердца, нарушений сердечного ритма), пульмональных (пневмоний, тромбоэмболии легочной артерии, респираторного дистресс-синдрома взрослых) и ренальных (острой почечной недостаточности). Некоторое исключение составили менее жизнеопасные тромботические осложнения. Полученные результаты имеют высокий уровень статистической значимости, что позволяет рекомендовать их к рассмотрению к использованию в практике сосудистой хирургии The article presents data from an original study to improve the surgical treatment of abdominal aortic aneurysms. For this purpose, a comparative analysis of two alternate operations was performed: 1) aneurysm resection followed by aortic prosthetics; 2) aortic endoprosthetics. The scientific hypothesis is formulated that the replacement of the «classical» operations of resection of the aneurysm with «alternative» operations of endoprosthetics will lead to a fundamental decrease in the level of postoperative complications. In independent groups of patients using the compared surgical interventions, an accurate qualitative and quantitative assessment of postoperative complications was made: non-thrombotic - cardiac, pulmonary, renal and thrombotic - deep vein thrombosis and prosthetic jaw thrombosis. After the study was completed, it was found that the fundamental replacement of «classical» operations with «alternative» reliably leads to a fundamental decrease in the level of the most life-threatening complications - cardiac (acute forms of coronary heart disease, cardiac arrhythmias), pulmonary (pneumonia, pulmonary thromboembolism, respiratory distress syndrome of adults) and renal (acute renal failure). Some exceptions were less life-threatening thrombotic complications. The results obtained have a high level of statistical significance, which allows us to recommend them for consideration in the practice of vascular surgery

IDENTIFICATION AND ASSESSMENT OF RISK FACTORS ROLE IN MYOCARDIAL INFARCTION DEVELOPMENT

2019 ◽  
Vol 72 (5) ◽  
pp. 779-783
Author(s):  
Victor A. Ognev ◽  
Anna A. Podpriadova ◽  
Anna V. Lisova
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Cardiovascular Disease ◽  
Cardiovascular System ◽  
Control Group ◽  
Biological Factors ◽  
Prevention And Treatment ◽  
High Level ◽  
Social Importance ◽  
The Impact

Introduction:The high level of morbidity and mortality from cardiovascular disease is largely due toinsufficient influence on the main risk factors that contribute to the development of myocardial infarction.Therefore, a detailed study and assessment of risk factors is among the most important problems of medical and social importance. The aim: To study and evaluate the impact of biological, social and hygienic, social and economic, psychological, natural and climatic risk factors on the development of myocardial infarction. Materials and methods: A sociological survey was conducted in 500 people aged 34 to 85. They were divided into two groups. The main group consisted of 310 patients with myocardial infarction. The control group consisted of 190 practically healthy people, identical by age, gender and other parameters, without diseases of the cardiovascular system. Results: It was defined that 30 factors have a significant impact on the development of myocardial infarction.Data analysis revealed that the leading risk factors for myocardial infarction were biological and socio-hygienic. The main biological factors were: hypertension and hypercholesterolemia. The man socio-hygienic factor was smoking. Conclusions: Identification of risk factors provides new opportunities for the development of more effective approaches for the prevention and treatment of myocardial infarction.

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