THE CONTENT OF ZINC AND CADMIUM IN BLOOD AND ORAL FLUID IN GENERALIZED PERIODONTITIS IN PEOPLE EXPOSED TO ADVERSE ENVIRONMENTAL FACTORS

2021 ◽  
Vol 74 (10) ◽  
pp. 2407-2411
Author(s):  
Zoryana B. Popovych ◽  
Mykola M. Rozhko ◽  
Iryna Z. Ostapyak ◽  
Oleksandra M. Ilnytska ◽  
Iryna Z. Chubiy ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Oral Fluid ◽  
Biological Fluids ◽  
Periodontal Diseases ◽  
Thermal Power ◽  
Heavy Metal Salts ◽  
Adverse Environmental Conditions ◽  
High Level ◽  
Somatic Diseases ◽  
Degree Of Severity

The aim: To study the content of trace elements (cadmium and zinc) in the blood and oral fluid in people with generalized periodontitis and work and live permanently in adverse environmental conditions. Materials and methods: In order to study the prevalence of periodontal diseases in adults living in areas with high level of soil contamination with heavy metal salts and working in the workplace with occupational hazards, there were studied 163 people who did not have somatic diseases, namely: 133 employees of Burshtyn Thermal Power Plant (TPP) and 30 persons who do not work at Burshtyn TPP. Results: The results of biochemical examination of blood and oral fluid in persons with generalized periodontitis of the I, II degree of severity and being exposed to adverse environmental factors, show changes in the trace element spectrum of blood and oral fluid, namely: a decrease in amount of zinc and an increase in amount of cadmium, which may indicate the disorder of microelement metabolism under conditions of chronic influence of small doses of salts of heavy metals. Conclusions: As a result of the performed study, a violation of micronutrient metabolism in biological fluids (blood and oral fluid) was found in persons exposed to adverse environmental factors.

Multiple chronic system diseases and periodontal pathology

2019 ◽  
Vol 24 (2) ◽  
pp. 127-131 ◽  
Author(s):  
L. M. Tsepov ◽  
A. I. Nikolaev ◽  
M. M. Nesterova ◽  
E. L. Tsepova ◽  
A. L. Tsepov
Keyword(s):  
Medical Records ◽  
Negative Impact ◽  
Periodontal Diseases ◽  
Internal Organs ◽  
Dental Patients ◽  
Dental Clinics ◽  
Tissue Protection ◽  
Gender And Age ◽  
Somatic Diseases ◽  
Degree Of Severity

Relevance: the prevalence and severity of chronic inflammatory periodontal diseases in multiple somatic diseases were assessed taking into account the gender and age of patients.Materials and methods: a retrospective analysis of 841 "medical records of dental patients" of adult patients of both sexes aged 31 to 83 years who applied to dental clinics in Smolensk was carried out. Documented data on periodontal pathology and internal organs and systems diseases in patients were taken into account.Results: it was established that the degree of severity of chronic inflammatory generalized periodontal disease in persons with somatic pathology is associated with the age of the patient, the duration and severity of the course of somatic diseases.Conclusions: the result of the negative impact of somatic pathology on the periodontal condition is a violation of metabolic processes and tissue protection factors of the periodontal complex, which predisposes to the development of its lesion or accelerates the implementation of the existing periodontal factors.

scholarly journals Evaluation of the bone tissue metabolism in patients with generalized periodontitis of various degrees exposed to work-related harmful factors by the oral fluid Klotho protein content

2021 ◽  
Vol 23 (2) ◽  
pp. 274-279
Author(s):  
I. V. Vozna ◽  
A. V. Samoilenko ◽  
S. V. Pavlov ◽  
O. O. Kokar
Keyword(s):  
Vitamin D ◽  
Bone Tissue ◽  
Protein Concentration ◽  
Oral Fluid ◽  
Comparison Group ◽  
Periodontal Diseases ◽  
Study Group ◽  
Work Related ◽  
Klotho Protein ◽  
Degree Of Severity

The aim of the work is to study the Klotho protein concentration in the oral fluid of patients exposed to work-related harmful factors and to reveal correlations with the content of bone tissue and vitamin D metabolism markers. Materials and methods. The study group consisted of 126 patients with generalized periodontitis of initial (n = 8), I (n = 32), II (n = 68) and III (n = 18) degree of severity, chronic course, working in hazardous conditions of the “Dniprospetsstal” plant in Zaporizhzhia. The comparison group consisted of 32 periodontitis patients of initial (n = 5), I (n = 10), II (n = 11) and III (n = 6) degree of severity without exposure to work-related harmful factors. The control group included 20 otherwise healthy individuals aged 19–25 years without signs of periodontal diseases. The levels of vitamin D, VDBP, MMP-8 and osteocalcin were determined by enzyme-linked immunosorbent assays, the concentration of soluble Klotho was detected by the enzyme-linked ImmunoChem-2100 immunosorbent assay. Results. It was found, that in the study group of patients working in hazardous work-related conditions, the decrease in oral fluid Klotho protein concentration was greater, than in the comparison group of patients with periodontal diseases, but not exposed to work-related hazardous conditions. The indicator of Klotho protein is an early marker of the periodontal disease progression and varies inversely with the severity of periodontitis, starting in the early stages of the disease. The correlation coefficient between the level of Klotho protein and the degree of the disease severity in the comparison group patients was γ = -0.957, P < 0.05 and γ = -0.906, P < 0.05 – in the study group. In the patients with periodontal diseases, there was a decrease in the Klotho protein concentration with a parallel increase in the marker of bone tissue destruction - MMP-8, and a decrease in the marker of remodeling – osteocalcin, as compared to the controls. The decrease in Klotho protein concentration occurred with vitamin D deficiency and worsened with the vitamin D-binding protein reduction. Conclusions. The Klotho protein is the early, sensitive and specific diagnostic biomarker in dental diseases, and its measurement can be used as a predictor of inflammatory periodontal disease and its complications. The Klotho protein is one of the main regulators of bone metabolic processes.

Modern problems of regionalization of territories and human adaptation in regions with extreme natural and climatic conditions

2021 ◽  
Author(s):  
A.L. Maksimov
Keyword(s):  
Environmental Factors ◽  
Environmental Conditions ◽  
Allostatic Load ◽  
Climatic Conditions ◽  
Extreme Conditions ◽  
Human Adaptation ◽  
Nonspecific Resistance ◽  
Key Words Adaptation ◽  
High Level ◽  
Selection Of

The paper considers modern approaches to the zoning of territories and the selection of people for life in extreme environmental conditions, taking into account modern geopolitical challenges. It is shown that it is possible, based on the allostasis concept, to conduct not only the selection of persons with a high level of nonspecific resistance, but also to quantify the degree of extremity of environmental factors using the standard represpiration test. Key words: adaptation, extreme conditions, selection, hypoxia, cold, rerespiration, allostatic load.

Uttarakhand

Mapping Power ◽  
2018 ◽  
pp. 296-318
Author(s):  
Jonathan Balls
Keyword(s):  
Low Cost ◽  
Thermal Power ◽  
Uttar Pradesh ◽  
The State ◽  
Power Sector ◽  
Hydro Power ◽  
High Level ◽  
Financial Base ◽  
Breathing Room ◽  
High Share

Uttarakhand was created out of Uttar Pradesh and endowed with a substantial benefit: sole access to cheap hydro power. Low-cost power allowed the state to attract industry by cutting tariffs, providing a stable financial base, and enabling a well-functioning sector. With low tariffs, the power sector has not become an arena for populist policies despite frequent electoral shifts. However, this comfortable situation also limited the pressure to use the breathing room created by low cost power coupled with high share of industrial consumption to address long-standing loss levels in other parts of the state. As the limits of low-cost power are reached, the threat to Uttarakhand’s high-level equilibrium comes from having to turn to high-cost thermal power and stagnating industrial consumption.

scholarly journals Den aldrende LAR pasienten

2017 ◽  
Vol 34 (1) ◽  
pp. 72-79 ◽  
Author(s):  
Hege Tollefsen Nyhagen ◽  
Helge Waal
Keyword(s):  
Social Services ◽  
The Elderly ◽  
Ovid Medline ◽  
Open Questions ◽  
Qualitative Interview Study ◽  
Somatic Comorbidities ◽  
National Cohort ◽  
Retention In Treatment ◽  
High Level ◽  
Somatic Diseases

Background: Opioid maintenance treatment (OMT) secures a low mortality in a vulnerable population and is often a lifelong treatment. One would therefore expect an increasing prevalence of OMT among the elderly. This article describes a study with three elements; a literature review, an investigation of occurrence and an exploration of elderly patients’ needs and experiences. Material and methods: PsycINFO, Ovid Medline and Embase were searched with reference words for opioid maintenance and age. Norway has a national cohort study of patients in OMT describing recruitment, retention in treatment, age and mortality. A prognosis of numbers in treatment older than 50 and 60 years were extrapolated based on probabilistic premises. Finally, a qualitative interview study of OMT patients in two municipalities near Oslo was performed. Five OMT patients aged between 58 and 64 years were interviewed with open questions on thoughts, needs and experiences. Findings: The review points to an increasing population with psychiatric and somatic comorbidities and diverse needs. Their opinions and experiences seem largely unexplored. The population estimates indicate that Norway by 2018 will have between 3084 and 3567 individuals older than 50 years and between 201 and 302 individuals older than 60 years in OMT. The qualitative study demonstrated that the elderly OMT patient typically attributes their being alive to OMT. It is a life with a high prevalence of ailments and diseases. Their somatic diseases are mostly adequately treated by their GP, but they feel left alone with a high level of mental problems and loneliness. They miss follow-up from the OMT and social services and are not met on existential thoughts and sorrow for their life. A wish to end OMT during their lifetime is noteworthy. This would necessitate a close collaboration with the OMT services and support from a social network. Conclusions: The study points to insufficient knowledge of and strategies to meet an increasing number of individuals with composite problems in OMT. The numbers will remain too small to warrant specially designed local projects, but large enough to necessitate awareness and competencies in the ordinary municipal health and social services.

scholarly journals A Therapeutic Educational Program in Oral Health for Persons with Schizophrenia: A Qualitative Feasibility Study

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Audrey Peteuil ◽  
Corinne Rat ◽  
Sahar Moussa-Badran ◽  
Maud Carpentier ◽  
Jean-François Pelletier ◽  
...  
Keyword(s):  
Oral Health ◽  
Educational Program ◽  
Periodontal Diseases ◽  
Level Of Evidence ◽  
Face To Face ◽  
Before And After ◽  
Health Quality ◽  
Persons With Schizophrenia ◽  
High Level ◽  
The Impact

Objective. The aim of this study was to test the feasibility of a therapeutic educational program in oral health (TEPOH) for persons with schizophrenia (PWS). Design. In a qualitative study, we explored the representation of oral health before and after a TEPOH. Clinical Setting: PWS are at greater risk of decayed and missing teeth and periodontal diseases. In a previous publication, we described the different steps in building a TEPOH by taking into account the experiences of PWS concerning oral health quality of life. This TEPOH aimed at promoting a global health approach. Participants: Voluntary PWS and their caregivers were recruited during face-to-face interviews at “Les Boisseaux” (a psychiatric outpatient centre) in Auxerre (France) and were included in the study between November and December 2016. Intervention: We explored the experiences of participants and their perceptions of oral health before and after the TEPOH with focus group meetings. Results. Four females and three males participated in the study, and the mean age was 29.4 ± 5. Before the TEPOH, the PWS produced 28 ideas about oral health perception and 37 after the TEPOH. After the TEPOH, elements relating to the determinants of oral health (smoking and poor diet) emerged. Conclusions. These results show an evolution in oral health representation, and after some adjustments to the TEPOH, the second step will be to test this program in a large sample to generate a high level of evidence of the impact of TEPOH in the long term.

Methodology in the Development Process of Large Gaseous Fuelled Engines

2003 ◽  
Author(s):  
Gerhard Kogler ◽  
Andreas Wimmer ◽  
Helmut Eichlseder ◽  
Eduard Schnessl ◽  
Hubert Winter
Keyword(s):  
Development Process ◽  
Thermal Power ◽  
Experimental Investigations ◽  
Block Type ◽  
Pyrolysis Gas ◽  
Simulation Tools ◽  
Power Stations ◽  
Thermal Power Stations ◽  
High Level ◽  
Fuel Consumption And Emissions

High demands are placed on large gaseous-fuelled engines regarding performance, fuel consumption and emissions. Because of the different applications of gaseous-fuelled engines (block-type thermal power stations, generation of electric power in a stand alone plant, etc.) and the use of different kinds of gases (natural gas, wood gas, pyrolysis gas, dump gas, etc.), the optimization process can be seen as a very complex task. Today engines have already reached a high level of development and further improvements can only be realized with very high expenditures. Experience has shown that a purely experimental approach is no longer sufficient and therefore the application of modern simulation tools is necessary. In this paper a combined development process is described consisting of simulation, experimental investigations on a single cylinder research engine and transfer on a full scale engine as an example for the optimization of a gas-purched prechamber concept.

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