ACUTE POISONING WITH DRUGS MAINLY AffECTING THE CARDIOVASCULAR SYSTEM

Author(s):  
M. V. Belova ◽  
K. K. Ilyashenko

Based on examined reports 2010-2014 of the department of acute poisonings treatment at the N.V.Sklifosovsky Research Institute of Emergency Medicine and 1197 medical records of in-patients, a general characterization of poisoning by drugs affecting preferably the cardio vascular system is presented. Preparations and their combinations that are the most frequent causes of poisoning are detected; the age and gender structure of patients, poisonings causes and lethality are considered

2020 ◽  
Vol 159 ◽  
pp. 01001
Author(s):  
Sultan Tuleukhanov ◽  
Zhanna Abdrassulova ◽  
Nurdana Salybekova ◽  
Gulzhaina Alpamyssova ◽  
Arina Kenshilik

This study provides examination of cardiovascular system of children who live in Ust-Kamenogorsk, mainly in its environmentally polluted areas as industrial zones and Ulbinsk region. The work focused on studying the age and gender characteristics of the cardio vascular system in children living in environmentally unfavorable conditions of Ust-Kamenogorsk. The study highlighted the role of contamination into the development of many diseases that affect cardiovascular system of children in various age categories. The features of cardiorespiratory system were evaluated by methods of pneumotachometry, variational pulsometry, electrocardiography, Holter daily monitoring of electrocardiography. There was detected a gradual increase in sympathetic regulation of heart rate in boys and humoral regulation in girls aged 9-12 years. It was shown that the resistance of children’s organism to the harmful environmental effects depend on their constitutional features. The increased level of stress also affects the well-being of children, as caused by the unfavourable conditions. The method of daily ECG monitoring revealed an increase in the frequency of elevation ST segment, to a lesser extent its depression, so the incidence of bradycardia is more often than tachycardia.


Author(s):  
K. K. Ilyashenko ◽  
A. Yu. Simonova ◽  
M. V. Belova

Based on the analysis of reports of the Department for treatment of acute poisonings at the N.V. Sklifosovskiy Research Institute of Emergency Medicine from 2009 to 2014 and medical records of in-patients hospitalized during that period, the structure of acute poisoning in elderly and senile patients was investigated. The share of patients of the senior age groups averages 12.5% of all patients. The most frequent reason for poisoning is a suicide attempt-71.9%. Psychopharmacological (46.5%) and cardiotropic (13.6%,) medications take the key place in poisonings as well as combined poisonings. The lethality analysis revealed its growth with increase in age of victims. One of the main causes of lethal outcomes is pneumonia.


2020 ◽  
Vol 56 (1) ◽  
pp. 15
Author(s):  
Husin Thamrin ◽  
Khafidhotul Ilmiah ◽  
Ni Wajan Tirthaningsih

Colorectal cancer has became burden in the world.The latest study shows that colorectal cancer is the third most common cancer in men and second most common cancer in women globally. There are difference characteristic of epidemiology in every countries. Moreover, there is no study that represents epidemiology of colorectal cancer in Indonesia yet, especially in East Java. The aim of this study was to describe colorectal tumor profile by age and gender in Gastroentero-Hepatology Center, Dr Soetomo Hospital. This study has received a certificate of Ethical Clearance No.273/Panke.KKE/IV/2015, a descriptive retrospective study. We collected data using medical records, and patients who have been colonoscopy examination and suspected colorectal tumor were included. There were 201 patients, divided to 100 males and 101 females. The peak of incidence was on 51-60 years old group, but on the 31-40 years old incidence of colorectal tumor was increased. The youngest patient was 17 years old. And tumors are more likely develop in distal area, especially in rectum. This study shows a different characteristic profile of colorectal tumor, where tumor is developed at young people and there is no significant difference between male and female for the incidence.


2015 ◽  
Vol 4 (1) ◽  
pp. 102-110
Author(s):  
Пахомов ◽  
A. Pakhomov ◽  
Прасолова ◽  
A. Prasolova ◽  
Козлова ◽  
...  

Using the methods of statistical analysis and methods of multidimensional phase spaces (analysis and calculation of the volume of quasi-attractors matrices mezhattraktornyh distances) studied the behavior of the state vector of the body girls (for example, the behavior of the parameters of the cardiovascular system) with transshirotnyh movements. The differences in the assessment of the dynamic behavior of the parameters of the cardio-vascular system, namely the decrease in quasi-attractors indicates good revitalizing effect two-week stay in a boarding house young children oilman. Analysis matrices mezhattraktonyh distances showed that the motion of chaotic and stochastic centers at latitude movements somewhat different girls: mezhattraktornye distance when driving chaotic center upon arrival to rest down, after a two-week vacation, it becomes even more, to return to the city of Surgut is similar to the results for the arrival at rest, indicating the lack of formation of the girls adaptive mechanisms, as well as a significant tension of regulatory processes and the degree of mismatch of functional systems at transshirotnyh movements.


Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Brent Williams ◽  
Peter Berger

Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia observed in clinical practice and is associated with an elevated risk of stroke and mortality. Evaluating community-level temporal trends in AF incidence and prevalence serve to describe the evolving public health and clinical burden of AF, however recent studies describing AF trends in community-based settings have been inconsistent, with no recent data evaluating trends among individuals under 65 years of age. Accordingly, this study sought to describe community-level trends in AF incidence and prevalence from 2004 to 2013 using the electronic medical records (EMR) of a single, large health care system. Methods: This study includes 329,634 patients receiving primary care and other health care services through the Geisinger Health System (Geisinger) over at least a two-year period. Geisinger consists of over 40 outpatient and seven inpatient facilities spread throughout central and northeastern Pennsylvania. Geisinger’s extensive EMR data repository contains information on demographics, vital signs, social history, diagnoses, medical history, problem lists, medications, procedures, laboratory results, and billing information from all Geisinger encounters since 2001. Incident and prevalent AF were identified by ICD-9 codes observed within any EMR domain. For incident AF, cases had no AF ICD-9 code in the EMR for at least two years prior to the diagnosis. Incidence and prevalence rates were age- and sex-adjusted to the 2010 US census and reported per 1000 person-years (persons). Stratified rates are reported across age groups (<45, 45-54, ¼, >85) and sex. Results: Age- and sex-adjusted AF incidence rates remained relatively stable from 2004 to 2008, but increased sharply thereafter. Incidence rates were 5.0, 5.2, and 8.4 cases per 1000 person-years in 2004, 2008, and 2013, respectively. The overall annual increase was 5.5% per year (95% CI: 4.8, 6.3%). Incidence rates increased significantly in all age and gender groups, with the largest relative increase observed among patients <45 years of age (annual increase in males: 10.8%, females: 11.6%). Prevalence rates increased consistently throughout the entire 10-year period from 23.5 to 39.2 AF cases per 1000 persons from 2004 to 2013 (6.0% annual increase; 95% CI: 5.7, 6.4%). Conclusions: AF incidence and prevalence have been increasing in the community over the last 10 years. Increases were observed in all age and gender groups, with notable increases in the very young. Prevailing trends may be attributable to increased application of AF diagnostics in an aging population and/or an increased clinical recognition of AF due to the recent availability of novel oral anticoagulants for stroke prevention. A mature EMR system functioning within a large health care system can be a powerful tool for performing epidemiologic studies and disease surveillance.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Milla Summanen ◽  
Liisa Ukkola-Vuoti ◽  
Samu Kurki ◽  
Samuli Tuominen ◽  
Rami Madanat

Abstract Background Osteoarthritis (OA) is a leading cause of disability and pain especially among older adults, but it is also known to affect working age individuals, often leading to reduced productivity and increased healthcare usage. The aim of this study was to determine the burden of hip and knee OA in Finnish occupational healthcare. Methods This was a retrospective registry study utilizing the electronic medical records of the largest private and occupational healthcare provider in Finland. All consented patients with hip or knee OA were identified. A subcohort of occupational healthcare (OCH) patients was then compared to an age- and gender-matched control group without OA. Patient demographics including comorbidities were determined and healthcare contacts, medication prescriptions, and sick leaves were compared between the two groups. The study period was from January 1st, 2012 to April 30th, 2020. Results 51,068 patients with hip or knee OA were identified (all OA cohort) and 35,109 of these formed the occupational healthcare subcohort. Most of the OA patients were female and belonged to the age group 50–59 years. The point prevalence of hip/knee OA at the end of the study period was 5.6% for the occupational healthcare subcohort. OA patients had 2.2 times more healthcare contacts and 2.8 times more overall sick leave days compared to the age- and gender-matched control cohort. Etoricoxib was the most commonly prescribed medication at OA-related visits (21.8% of patients). Opioids were prescribed to 10.6% of patients at OA-related visits and the most prescribed opioid was a combination of codeine and paracetamol (4.8% of patients). 5054 OA patients (14.4%) had a contraindication for non-steroidal anti-inflammatory drugs (NSAIDs). Conclusions This retrospective registry study utilizing real-world data provides new evidence on the disease burden of hip or knee osteoarthritis from the electronic medical records of Finnish occupational healthcare customers. OA patients had more comorbidities, more healthcare contacts, more sick leave days, and more analgesic prescriptions compared to an age- and gender-matched control cohort without OA.


2019 ◽  
Vol 3 (1) ◽  
pp. 14-27
Author(s):  
Griselda Griselda ◽  
Kemas Ya'Kub Rahadiyanto ◽  
Rachmat Hidayat

Background Liver cirrhosis is a disease with high morbidity and mortality in Indonesia. The Child-Turcotte-Pugh classification is a noninvasive parameter to assess severity of liver cirrhosis. Meanwhile, the neutrophil/lymphocyte ratio can reflect person's immunity to liver cirrhosis. This study was conducted to determine the agreement between neutrophil/lymphocyte ratio and Child-Turcotte-Pugh classification in assessing severity of liver cirrhosis. Methods Analytical observational study with Cohen’s Kappa agreement test was conducted in 86 liver cirrhosis patients. Data was retrieved by observing the medical records. Neutrophil count, lymphocyte count, hepatic encephalopathy, ascites, albumin, bilirubin, and INR were all recorded. Documented variables were analyzed by the Cohen’s Kappa agreement test. Results In Cohen’s Kappa agreement test, there was moderate agreement between neutrophil/lymphocyte ratio and Child-Turcotte-Pugh classification in all samples (κ = 0.591 and p <0.001). Agreement between neutrophil/lymphocyte ratio and Child-Turcotte-Pugh classification based on age and gender was found to be κ = 0.777 at age ≤45 years, κ = 0.532 at age >45 years, κ = 0.682 in male, and κ = 0.445 in female (p <0.001). The highest agreement is the substantial agreement between neutrophil/lymphocyte ratio and Child-Turcotte-Pugh classification obtained at age ≤45 years (κ = 0.777 and p <0.001) and male (κ = 0.682 and p <0.001). Conclusion There is moderate agreement between neutrophil/lymphocyte ratio and Child-Turcotte-Pugh classification in assessing severity of liver cirrhosis. Substantial agreement obtained at age ≤45 years and male gender.   Keywords: Neutrophil/Lymphocyte Ratio, Child-Turcotte-Pugh, Liver Cirrhosis


2005 ◽  
Vol 27 (2) ◽  
pp. 131-134 ◽  
Author(s):  
Carolina de Mello-Santos ◽  
José Manuel Bertolote ◽  
Yuan-Pang Wang

OBJECTIVE: To describe the suicide rates in Brazil in recent decades, drawing comparisons with the worldwide epidemiological situation. METHODS: Descriptive analyses of Brazilian suicide data, relating to the 1980-2000 period and extracted from the DATASUS database. Brazilian suicide trends were examined by age and gender. RESULTS: The overall rate of suicide in Brazil increased 21% in 20 years. Men were found to be 2.3 to 4.0 times more likely to commit suicide than were women, and the highest suicide rates were found in the over-65 age group. The greatest increase in suicide rates (1900%) was seen in the 15-24 age range. CONCLUSION: Brazilian suicide rates, although low, are consistent with the global trend toward growth. Although the highest rates are still seen among the elderly, members of the younger population have been killing themselves with ever-increasing frequency.


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