scholarly journals Prevalence of celiac disease in irritable bowel syndrome patients: A single centre experience from a large teaching hospital of Lahore, Pakistan

2021 ◽  
Vol 14 (4) ◽  
pp. 176-179
Author(s):  
Mohammad Ahmed Saifullah ◽  
Amer Ahmad Khan ◽  
Sarmad Zahoor ◽  
Sidra Saif ◽  
Javed Sajjad Hashmi ◽  
...  

Background: Many studies have been conducted worldwide to evaluate the proportion of patients with Celiac disease (CD) in persons presenting with Irritable Bowel Syndrome (IBS), showing a positive association between the two diseases. However, reports from Pakistan remain scanty. This study aims to find out the prevalence of CD in patients presenting with IBS and to establish the correlation of both diseases. Patients and methods: It was a descriptive cross-sectional study conducted at Combined Military Hospital, Lahore (CMHL) from January 2018 till March 2019. Consecutive, nonprobability sampling was used to include 210 patients of both genders with the age range of 15-65 years fulfilling ROME IV criteria and were not previously diagnosed as CD or CKD or CLD. Demographic data was noted. Serum Anti tTG levels and Duodenal Biopsy from the second part was assessed to diagnose CD. CD was labeled if the disease was present on both serological and Histopathological reports. Data were analyzed by using SPSS version 20. Descriptive statistics were calculated and a Chi-square test was used to compare the outcome variables with P-value < 0.05 as significant. Results: Of 210 enrolled patients, 113 (53, 8%) were male and 97 (46.2%) were female. The mean age of the patients was 28.40 ± 5.06 years. Eight patients (3.8%) were positive for Anti tTg and on histopathological findings suggestive of CD. Seven of 8 were less than 35 years old. Out of 8 positive patients, 6 (75%) were females. However, the p-value was found to be insignificant for age (0.549) and gender (0.096). On stratification with respect to duration of IBS, all 8 patients diagnosed with celiac disease were having symptoms of IBS for less than 12 months (100%) which was significant statistically (7.1% vs 0.0%; p=0.007). Conclusion: The frequency of CD was 3.8% among IBS patients. Considering this percentage of CD in IBS patients s, a high index of suspicion for CD in IBS patients is required,

2020 ◽  
Vol 70 (6) ◽  
pp. 1681-85
Author(s):  
Kanwal Jehanzeb ◽  
Zia Ul Haq ◽  
Saeed Zaman Khattak ◽  
Sajid Ali Shah ◽  
Munir Akmal Lodhi ◽  
...  

Objective: To assess the occurrence and intensity of Giardia and Ascaris infestations in children of both genders reporting with diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Paediatrics department, Combined Military Hospital, Gilgit, from Jul 2016 to Jul2018. Methodology: Patients of either gender with worm infestation were included in the study. Patients more than13 years old were excluded. The sampling technique used was non probability consecutive sampling. The stoolexamination (R/E) for the diagnosis of worm infestation was done. Stratification was done with regards to age,mother education, gender, type of water used and post stratification chi square test was applied. p-value was0.613 when calculated for the manifestation between both genders. p-value ≤0.05 was considered significant. Results: Total number of patients in our study was 100. Among them, males were 65 (65%) and females were 35(35%). Mean age of patients in our study was 4.20 ± 2.61 years (Mean ± SD). Abdominal pain being most common symptom in 43 (43%) of patients. Majority of the patients were from 2 to 10 years of age, 79 (79%). Helminthic infestation was the most common observed in 52 (52%) whereas Protozoal infestation was observed in 48 (48%) patients. The most common parasite isolated was Giardia 41 (41%) followed by Ascaris 36 (36%). p-value of 0.613 was found between both gender. Conclusion: In our study Helminthic infestation was more common. The most common parasite isolated wasGiardia followed by Ascaris.


Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4513
Author(s):  
Elodie Schneider ◽  
Jean-Marc Sabaté ◽  
Michel Bouchoucha ◽  
Serge Hercberg ◽  
Mathilde Touvier ◽  
...  

(1) Background: Specific foods, and more particularly, fermentable oligo-, di-, and mono-saccharides and polyols (FODMAPs) are often considered as triggers of digestive symptoms in Irritable Bowel Syndrome (IBS). Our aim was to study FODMAP consumption in controls and IBS participants in a large French population-based cohort; (2) Methods: Participants from the NutriNet-Santé cohort study completed the Rome IV and IBS-SSS questionnaire in a cross sectional study. Among them, 27,949 eligible participants had previously completed three 24-h recalls as well as anthropometrics, socio-demographical and lifestyle data. Total FODMAP intake (in g/day) was computed using a specific composition table. The association between FODMAPs and IBS was estimated through multivariable logistic regression models; (3) Results: Included participants were mainly women (75.4%) and the mean age was 43.4 ± 14.1 years. FODMAPs accounted for a mean daily intake of 19.4 ± 9.5 g/day. Overall 1295 participants (4.6%) were identified with an IBS. After adjusting for confounding factors, IBS participants had lower intakes in FODMAPs than non-IBS ones (aOR: 0.88, 95% CI: 0.82–0.95, p-value: 0.001). IBS severity was associated with more frequent low FODMAP intakes (<9 g/day); (4) Conclusions: Participants tended to consume 19 g of FODMAPs per day, but slightly less for IBS participants than for controls. In IBS participants, higher severity was associated with lower intakes.


Author(s):  
Steven Nanda ◽  
Veli Sungono

Background: Irritable bowel syndrome is a functional disorder with recurrent abdominal discomfort associated with abnormalities in gut motility. One of the risk factors for IBS is anxiety and depression. This study aims to find out the relationship between medical student’s psychosocial conditions, measured by depression and anxiety with incidence of IBS. Gastrointestinal-specific anxiety (GSA), a subset of general anxiety, is measured and its relationship with incidence of IBS is also evaluated.Method: This research is a cross sectional study. Sample consists of 168 medical students from UPH batch 2016-2018 that fits into inclusion and exclusion criteria. Data is collected with demographics questionnaire, Rome IV IBS Criteria, Depression, Anxiety and Stress Scale 21, and Visceral Sensitivity Index. Categorical data between depression and anxiety and IBS is analyzed with Chi Square. GSA is a numerical data and its relationship with IBS is analyzed with t-test. Because GSA All statistical data is analyzed using SPSS version 22.0.Results: Results showed that from 168 samples that are acquired for this research, 65 (38,7%) are IBS and 103 (61,3%) are non-IBS. Significant associations are found between depression (p=0,03), anxiety (p=0,039), gastrointestinal-specific anxiety (p0,001), and obesity (p=0,026) with incidence of IBS.Conclusion: There is a significant association between depression and anxiety with incidence of IBS.


2020 ◽  
Author(s):  
Adam Miraj Gembe

Abstract Background: Global prevalence of irritable bowel syndrome is high among medical students and health care professionals with significant morbidity. Similarly, the prevalence of celiac disease in irritable bowel syndrome is higher than the general population. These conditions impair quality of life and contribute to social-economic burden. In Tanzania, little is known about irritable bowel syndrome and celiac disease among medical students and health care professionals. Methods: A cross sectional study was conducted to MUHAS and Mloganzila Academic Medical Center (MAMC) staff and students who fulfilled the online shared Rome IV criteria of irritable bowel syndrome from August to November 2018. A structured questionnaire was used to collect socio-demographic data, anthropometric measurements and clinical manifestations. Blood samples for full blood picture, liver enzymes and Erythrocyte Sedimentation Rate were taken. Celiac disease was tested using anti-tissue transglutaminase antibody test. Qualitative and quantitative data were summarized using frequency distribution tables. Chi-square and fishers exact test were used to study comparison between groups. Logistic regression was used to study associations. Data was analyzed using SPSS version 20.0 and a P value of ≤0.05 was considered significant.Results: Out of 1,321 participants, 192 (14.5%) had irritable bowel syndrome in which 77 (40.1%) were males and 115 (59.9%) were females. Among the 192 participants with irritable bowel syndrome, 3 (1.6%) were positive for celiac disease, 2 (66.7%) were females and 1 (33.3%) was a male. Of the 3 patients with CD, 2 had elevated ALAT and 1 had anaemia. Age (AOR 2.53, 95% C.I 1.57-4.09), sex (AOR 1.67, 95% C.I 1.16-2.41), marital status (AOR 4.95 C.I 2.07-11.82), alcohol intake (AOR 2.47, 95% C.I 1.16-5.23), year of study (AOR 8.49, 95% C.I 5.71-12.64) and sleep duration (AOR 2.24, 95% C.I 1.23-4.06) were found to be independently associated with IBS. Conclusion: Prevalence of IBS and its associated factors in our study population was similar to findings from studies done elsewhere. Also, our study revealed a low prevalence of celiac disease among IBS participants.


2020 ◽  
Vol 70 (6) ◽  
pp. 1717-22
Author(s):  
Mobeen Ikram ◽  
Saira Mahboob ◽  
Sadia Zaineb

Objective: To evaluate the factors for perioperative patient satisfaction in parturient undergoing lower section cesarean section, with a view assess anesthesia quality. Study design: cross sectional, analytical study Place and Duration of study: Department of Anesthesiology and Gynecology & Obstetrics, Combined Military Hospital, Okara Cantt for 04 months from January to April 2019. Material and method: A total of 400 parturient undergoing cesarean section were included in our study. The patients were given a questionnaire to fill on discharge. Our outcomes were frequency of patient satisfaction and various factors affecting it. SPSS version 20 was used to analyze data. Mean ± SD was described for quantitative variables and frequency (percentage) for qualitative variables. T-test and chi square used to analyze significance. p-value ≤0.05 taken as significant. Results: A total of 400 questionnaires were assessed in final analysis. The overall patient satisfaction was 382 (95.5%) with 4 (1%) showing dissatisfaction; whereas 14 (3.5%) didn’t answer this question. 395 (98.8%) underwent LSCS under spinal anesthesia. There wasno difference in patient satisfaction in regards to intra-operative concern alleviation, discomfort, previous number of LSCS, parturient age, choice of anesthesia; p value > 0.05. There was higher dissatisfaction in patients who experienced post-operative complaints, most notably pain; p=0.000. Patient satisfaction was higher in mothers who experienced joy on hearing their newborns cries; p=0.000 Conclusion: The overall patient satisfaction in our study was high and only few factors causing patient dissatisfaction which included postoperative complaints most notably pain.


2013 ◽  
Vol 15 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Ali Akbar Shayesteh ◽  
Eskandar Hajiani ◽  
Seyed Jalal Hashemi ◽  
Abdolrahim Masjedizadeh ◽  
Seyed Mahmod Latifi ◽  
...  

2014 ◽  
Vol 8 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Daniella Antunes Pousa Faria ◽  
Luciana Silva Revoredo ◽  
Maria José Vilar ◽  
Maia Eulália Maria Chaves

Background: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune, rheumatic inflammatory disease that can cause significant morbidity with evident psychological impacts and obvious harm to quality-of-life that require the patient to adapt treatment. Objective: Assessment of resilience and the self-reported treatment adhesion behaviors of patients with SLE, investigating which of these factors are associated to resilience. Method: Cross-sectional study of 40 women with SLE. A questionnaire with social demographic data, health history and the Wagnild Young Resilience Scale were used. Results: 62.5% followed the medical treatment properly but 55% found it difficult. 27.5% of the patients presented low resilience, 57.5% medium and 15% high resilience. Resilience was associated in the chi-square test (p-value < 0.05) with the variables work, understanding SLE, trying to find out about SLE, following the treatment correctly, difficulty in following the treatment and stopping some activity because of the disease. In the correlation analysis, resilience was associated with age (-0.3960), number of working hours (0.5533), specialized treatment duration (-0.8103) and disease duration from diagnosis (-0.8014). Conclusion: Patients with high resilience tended to follow treatment correctly, tried to understand the disease and adhered more to the treatment to avoid risks and promote protection factors. Therefore knowledge of resilience in patients with SLE is necessary. It is important that the state takes necessary actions to facilitate access to treatment, to educational programs and to medical support. Awareness and counselling sessions must be initiated to develop and promote individual capacities to learn how to tackle with the disease for which psychological support of family and doctors can play a significant role.


2020 ◽  
Vol 4 (2) ◽  
pp. 113-121
Author(s):  
Fadhilah Rosyid Pradana ◽  
Sri Widiyati ◽  
Arwani Arwani

Background: Tuberculosis (TB) in children needs special attention. Enforcement of the diagnosis of childhood TB which is an important component in controlling pulmonary TB itself. Nurses as health workers have a role as providers of nursing care, educators, communicators and extension agents needed in an effort to overcome diseases including pulmonary TB in children. The nurse is also one of the human resources or health workers trained and responsible for implementing pulmonary TB prevention programs. For this reason nurses are required to have competent knowledge.Purpose: To determine the relationship of characteristics with the level of knowledge of nurses about pulmonary TB in children in the Health Center’s area of Semarang City.Methods:.This study used a descriptive survey design with a cross sectional study design. The sampling technique uses purposive sampling. The number of respondents was 44 respondents. The instruments used were questionnaires about demographic data and the level of knowledge about pulmonary TB in children. The data was analised using chi square.Results:.The results of this study using the Chi-square test obtained p value (Age 0.677), (Gender 0.531), (Education Level 0.230), and (Working Period 0.424) which shows p-value 0.05.Conclusion: There is no correlation between the characteristics and level of knowledge of nurses about pulmonary TB in children in Health Center’s area of Semarang.


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