The Global Cost of Endodontic Therapies

Author(s):  
Goldberg M

The yearly global economic impact of dental diseases is about $442 billion. The direct costs due to dental diseases are $298 billion annually, corresponding to 4.6% of global health expenditure. Each year an amount of $400 billion is spent, including millions of dental procedures and pointing to imperative needs for tooth therapies.

2021 ◽  
Vol 49 (1) ◽  
Author(s):  
Yusuff Adebayo Adebisi ◽  
Aishat Alaran ◽  
Abubakar Badmos ◽  
Adeola Oluwaseyi Bamisaiye ◽  
Nzeribe Emmanuella ◽  
...  

Abstract Background The goal of Universal Health Coverage (UHC) is to ensure that everyone is able to obtain the health services they need without suffering financial hardship. UHC remains a mirage if government health expenditure is not improved. Health priority refers to general government health expenditure as a percentage of general government expenditure. It indicates the priority of the government to spend on healthcare from its domestic public resources. Our study aimed to assess health priorities in the Economic Community of West African States (ECOWAS) using the health priority index from the WHO’s Global Health Expenditure Database. Method We extracted and analysed data on health priority in the WHO’s Global Health Expenditure Database across the 15 members of the ECOWAS (Benin, Burkina Faso, Cabo Verde, Cote d'Ivoire, The Gambia, Ghana, Guinea, Guinea-Bissau, Liberia, Mali, Niger, Nigeria, Senegal, Sierra Leone, and Togo) from 2010 to 2018 to assess how these countries prioritize health. The data are presented using descriptive statistics. Results Our findings revealed that no West African country beats the cutoff of a minimum of 15% health priority index. Ghana (8.43%), Carbo Verde (8.29%), and Burkina Faso (7.60%) were the top three countries with the highest average health priority index, while Guinea (3.05%), Liberia (3.46%), and Guinea-Bissau (3.56%) had the lowest average health priority in the West African region within the period of our analysis (2010 to 2018). Conclusion Our study reiterates the need for West African governments and other relevant stakeholders to prioritize health in their political agenda towards achieving UHC.


2021 ◽  
Author(s):  
Federico Rojo ◽  
Esther Conde ◽  
Héctor Torres ◽  
Luis Cabezón-Gutiérrez ◽  
Dolores Bautista ◽  
...  

Abstract Background: Detection of the ROS1 rearrangement is mandatory in patients with advanced or metastatic non-small cell lung cancer (NSCLC) to allow targeted therapy with specific inhibitors. However, in Spanish clinical practice ROS1 determination is not yet fully widespread. The aim of this study is to determine the clinical and economic impact of sequentially testing ROS1 in addition to EGFR and ALK in Spain.Methods: A joint model (decision-tree and Markov model) was developed to determine the cost-effectiveness of testing ROS1 strategy versus a no-ROS1 testing strategy in Spain. Distribution of ROS1 techniques, rates of testing, positivity, and invalidity of biomarkers included in the analysis (EGFR, ALK, ROS1 and PD-L1) were based on expert opinion and Lungpath real-world database. Treatment allocation depending on the molecular testing results was defined by expert opinion. For each treatment, a 3-states Markov model was developed, where progression free survival (PFS) and overall survival (OS) curves were parameterized using exponential extrapolations to model transition of patients among health states. Only medical direct costs were included (€ 2021). A lifetime horizon was considered and a discount rate of 3% was applied for both costs and effects. Both deterministic and probabilistic sensitivity analyses were performed to address uncertainty.Results: A target population of 8,755 patients with advanced NSCLC (non-squamous or never smokers squamous) entered the model. Over a lifetime horizon, the ROS1 testing scenario produced additional 157.5 life years and 121.3 quality-adjusted life years (QALYs) compared with no-ROS1 testing scenario. Total direct costs were increased up to € 2,244,737 for ROS1 testing scenario. The incremental cost-utility ratio (ICUR) was 18,514 €/QALY. Robustness of the base-case results were confirmed by the sensitivity analysis.Conclusions: Our study shows that ROS1 testing in addition to EGFR and ALK is a cost-effective strategy compared to no-ROS1 testing, and it generates more than 120 QALYs in Spain over a lifetime horizon. Despite the low prevalence of ROS1 rearrangements in NSCLC patients, the clinical and economic consequences of ROS1 testing should encourage centers to test all advanced or metastatic NSCLC (non-squamous and never-smoker squamous) patients.


2012 ◽  
Vol 15 (7) ◽  
pp. A497
Author(s):  
P. Panopoulou ◽  
F. Garcia-Contreras ◽  
J.A. Paladio-Hernandez ◽  
J.L. Huerta ◽  
E. Gonzalez Pier

2017 ◽  
Vol 20 (9) ◽  
pp. A543-A544
Author(s):  
A Skroumpelos ◽  
P Naoum ◽  
K Athanasakis ◽  
E Argyropoulos ◽  
A Koutsogianni ◽  
...  

2000 ◽  
Vol 50 ◽  
pp. 191
Author(s):  
Boris Krahulec ◽  
Peter Minarik ◽  
Miroslav Gudaba ◽  
Lujza Štrbova ◽  
František Valašek ◽  
...  

2021 ◽  
Vol 6 (7) ◽  
pp. e005799
Author(s):  
Matthew T Schneider ◽  
Angela Y Chang ◽  
Abigail Chapin ◽  
Catherine S Chen ◽  
Sawyer W Crosby ◽  
...  

IntroductionNational Health Accounts are a significant source of health expenditure data, designed to be comprehensive and comparable across countries. However, there is currently no single repository of this data and even when compiled major gaps persist. This research aims to provide policymakers and researchers with a single repository of available national health expenditures by healthcare functions (ie, services) and providers of such services. Leveraging these data within statistical methods, a complete set of detailed health expenditures is estimated.MethodsA methodical compilation and synthesis of all available national health expenditure reports including disaggregation by healthcare functions and providers was conducted. Using these data, a Bayesian multivariate regression analysis was implemented to estimate national-level health expenditures by the cross-classification of functions and providers for 195 countries, from 2000 to 2017.ResultsThis research used 1662 country-years and 110 070 data points of health expenditures from existing National Health Accounts. The most detailed country-year had 52% of the categories of interest reported. Of all health functions, curative care and medical goods were estimated to make up 51.4% (uncertainty interval (UI) 33.2% to 59.4%) and 17.5% (UI 13.0% to 26.9%) of total global health expenditures in 2017, respectively. Three-quarters of the global health expenditures are allocated to three categories of providers: hospital providers (35.4%, UI 30.3% to 38.9%), providers of ambulatory care (25.5%, UI 21.1% to 28.8%) and retailers of medical goods (14.4%, UI 12.4% to 16.3%). As gross domestic product increases, countries spend more on long-term care and less on preventive care.ConclusionDisaggregated estimates of health expenditures are often unavailable and unable to provide policymakers and researchers a holistic understanding of how expenditures are used. This research aggregates reported data and provides a complete time-series of estimates, with uncertainty, of health expenditures by health functions and providers between 2000 and 2017 for 195 countries.


2014 ◽  
Vol 95 (1) ◽  
pp. 128-130
Author(s):  
V Yu Kruchinin

Aim. To study the influence of dental diseases and results of their treatment on patient’s psychological profile. Methods. 40 patients with hard teeth tissues and dentition defects at the esthetic zone aged from 30 to 57 years were included in the study. Control group consisted of 25 people not requiring dental treatment. A new method of determining patient’s psychological subtype, offered by A. Anuashvili and based on computer analysis of the patient’s photographs, allowing totally avoid the subjectivity of a diagnosis. Results. Analysis of emotional stress level in patients before the dental procedures showed that it was significantly higher in males compared to females (73.6±0.86 vs 57.9±0.93% respectively, р 0,01). It was also found that 60% of all patients had unstable aspects of psychological subtype regardless of gender. In the control group, only minor changes of psychoemotional state between two examinations were registered, allowing to conclude that psychoemotional state without strong stimuli is quite stable. The use of the video-computed psychoanalysis method can help a dentist to assess the patient’s psychoemotional status when patient is seeking for dental aid, and to communicate better considering the patient’s psychological subtype, as well as to control psychoemotional state during and after the treatment. Conclusion. Missing teeth not only impair chewing, but also deteriorate patient’s psychoemotional state, leading to worse quality of life.


Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2245
Author(s):  
Yiping Zhu ◽  
Wuyan Jiang ◽  
Reed Holyoak ◽  
Bo Liu ◽  
Jing Li

The objective of this study was to investigate the oral microbial composition of the donkey and whether basic dental treatment, such as dental floating, would make a difference to the oral microbial environment in donkeys with dental diseases using high-throughput bacterial 16S rRNA gene sequencing. Oral swab samples were collected from 14 donkeys with various dental abnormalities on day 0 (before treatment) and day 20 (twenty days after treatment). It is the first report focusing on the oral microbiome in donkeys with dental diseases and the impact of common dental procedures thereon. Identified in group Day 0 and group Day 20, respectively, were 60,439.6 and 58,579.1 operational taxonomic units (OTUs). Several taxa in Day 0 differed significantly from Day 20 at the phylum and genus levels, but no statistically significant difference was observed in richness and diversity of Day 0 and Day 20. The results also indicated that a larger-scale study focusing on healthy donkey oral microbiome, as well as the correlation of dental diseases and oral microbiomes at different time frames following more specific and consistent dental treatment, are warranted.


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