scholarly journals THE ANALYSIS OF EFFICACY OF “CEFPOTEC” AND “CLABEL” PREPARATIONS IN TREATMENT OF SPECIFIC AND NONSPECIFIC PROSTATITIS

2019 ◽  
pp. 44-50
Author(s):  
Юрий Заседа
Keyword(s):  
Oral Administration ◽  
Chronic Prostatitis ◽  
Prostate Gland ◽  
Health Clinic ◽  
Mixed Infections ◽  
Infectious Agents ◽  
Bacteriological Examination ◽  
Prospective Design ◽  
Sonographic Examination ◽  
Pcr Diagnostics

Objective: to establish the eff ectiveness of Сefpotek (cefpodoxime) and Сlabel (clarithromycin) drugs in the treatment of chronic prostate infl ammation in the stage of pronounced exacerbation caused by nonspecifi c infectious agents and infections of the mycoplasma and chlamydia groups.Materials and methods. The study was conducted in a prospective design on parallel groups. The study contingent consisted of 60 patients of the “Men’s Health Clinic”, suff ering from chronic prostatitis in state of pronounced exacerbation. The following research methods were used: sonographic examination of the prostate gland, bacteriological examination of the ejaculate, analysis of ejaculate and PCR diagnostics of specifi c infections.The results of the study. A diff erentiated course of etiotropic therapy was carried out. In case of non-specifi c prostatitis: oral administration of the drug “Cefpotek” (cefpodoxim) 1 tablet (200 mg) 2 times a day for a course of 14 days with the possibility of extending the course to 28 days. With specifi c prostatitis: oral administration of the drug “Clabel” (clarithromycin) 1 tablet (500 mg) 2 times a day for a course of 14 days.Conclusions. In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by nonspecifi c infectious agents using oral administration of the drug “Сefpotek”, the full eff ectiveness was achieved in range from 83.3% to 96.6% of observations.In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by infectious agents of the mycoplasma and chlamydia groups using oral administration of the drug “Clabel”, the full eff ectiveness was achieved in the range from 80.0% to 86.6% of observations (regardless of features of combinations of specifi c mixed infections).

scholarly journals EXPERIENCE OF NIFURATEL USAGE IN COMPLEX TREATMENT OF CHRONIC SPECIFIC BACTERIAL FIBROUSE AND CALCULOUS PROSTATITIS ASSOCIATED WITH TRICHOMONIASIS AND CANDIDOSIS

2018 ◽  
pp. 33-37
Author(s):  
Юрий Заседа
Keyword(s):  
Oral Administration ◽  
Mixed Infection ◽  
Trichomonas Vaginalis ◽  
Infectious Agents ◽  
Complex Treatment ◽  
Total Dosage ◽  
Candida Spp ◽  
Sonographic Examination ◽  
Pcr Method ◽  
Therapeutic Model

The aim of the study was to analyze the effi cacy of the drug “Macmiror” (active substance – nifuratel) in the treatment of chronic specifi c bacterial fi brous and calculous prostatitis associated with trichomoniasis and candidiasis.Materials and methods. The study was conducted on 50 patients of the “Clinic “Men’s Health”, suff ering from chronic specifi c bacterial fi brous and calculous prostatitis (mixed infection: trichomonadial-bacterial-candidiasis associates of various structure). As methods of research, in addition to the standard complex, the following were chosen: IN POUCH TV-test; PCR method; sonographic examination ofthe prostate and spermogram.Results of the study. Patients who completed the study were treated with chronic specifi c bacterial fi brous and calculous prostatitis (N41.1) for 14 days, according to the following therapeutic model: oral administration of nifuratel as part of the “Macmiror” preparation at a total dosage of 1200 mg per day (6 tablets of 200 mg) divided into 3 doses and physiotherapy.Conclusions. A general (in relation to diff erent types and combinations of infectious agents) of the therapeutic model has been established at a level of 71% to 100%. Treatment had absolute (clinical and laboratory) effi cacy against isolated Candida spp.; absolute clinical effi cacy and 71-85% laboratory effi cacy against isolated Trichomonas vaginalis; 92% clinical and 76-84% laboratory effi cacy against the combination of these infectious agents; 92% clinical and 80% laboratory effi cacy against the combination of these infectious agents and non-specifi c bacterial fl ora, as the etiological factors of chronic specifi c bacterial prostatitis.

scholarly journals EXPERIENCE OF USE OF OFOR AND GYNEKIT IN THE TREATMENT OF PROSTATITIS ASSOCIATED WITH SPECIFIC AND MIXED MICROBIAL FLORA

2017 ◽  
pp. 39-43
Author(s):  
Юрий Заседа ◽  
Фарид Шыхалиев ◽  
Руслан Соломенный
Keyword(s):  
Prospective Study ◽  
Trichomonas Vaginalis ◽  
Prostate Gland ◽  
Microbial Flora ◽  
Health Clinic ◽  
Sonographic Examination ◽  
Clinical Recovery ◽  
Combined Application ◽  
Pcr Method ◽  
Therapeutic Model

Purpose of the study – establish the eff ectiveness of «Ofor» and «Gynekit» use in sequential combined application in the therapy of prostate gland infl ammatory diseases, which associated with a specifi c and mixed microbial flora.Materials and methods. A clinical prospective study was conducted, 30 patience of outpatient department of the «Men’s Health» clinic, suff ering from infl ammatory diseases of the prostate gland, took part in it. As methods of research, in addition to standard complex, the following were chosen: IN POUCH TV-test; Androfl or (PCR method); sonographic examination of the prostate and spermogram. Results of the study. The study found that in the general contingent clinical recovery was registered in 29 patients (96.7% of the total contingent), laboratory – in 27 cases (90% of the total contingent). The return of symptoms in 3 months was registered in 2 patients (6.7% of the total contingent).Conclusions. The level of eff ectiveness of “Ofor” and “Gynekit” use in combination with a set of auxiliary pharmaco and physiotherapy for patients, who suff ering from infl ammatory diseases of the prostate gland, associated with specifi c and mixed microbial fl ora, reaches 96.7%. Analysis of the etiological variability of the clinical eff ect indicates the presence of single cases of incomplete eff ect of this therapeutic model, with the etiology of the disease associated with Trichomonas vaginalis.

POSSIBILITIES OF ANTIOXIDANT PROTECTION IN PATIENTS WITH SUPERIOR HYPERPLASIA OF THE PEDESTAL GLAND AND ACCOMPANYING CHRONIC POSTATITIS

2020 ◽  
pp. 8-11
Author(s):  
Павел Георгиевич Осипов ◽  
Андрей Александрович Береш ◽  
Юрий Сергеевич Ханин ◽  
Олеся Игоревна Некрылова
Keyword(s):  
Lipid Peroxidation ◽  
Chronic Prostatitis ◽  
Antioxidant Defense ◽  
Prostate Gland ◽  
Antioxidant Defense System ◽  
Complex Treatment ◽  
Traditional Treatment ◽  
Important Place ◽  
Antioxidant Defense Systems ◽  
Benign Hyperplasia

Несмотря на достигнутые успехи в диагностике и лечении, на сегодняшний день проблема хронического простатита у пациентов с доброкачественной гиперплазией простаты продолжает оставаться актуальной. Тем временем, выздоровление или же стойкая ремиссия хронического простатита наступает только у 30-35% больных, которые получают традиционное лечение. В патогенезе хронического простатита важное место занимают мембранопатологические процессы, которые обусловлены активацией перекисного окисления липидов и нарушением состояния антиоксидантной системы защиты. У больных с хроническим простатитом и доброкачественной гиперплазией простаты наблюдается существенное усиление процессов липопероксидации на фоне сниженной функциональной способности антиоксидантных систем защиты организма. Поэтому равновесие в оксидантно-антиоксидантной системе является важным звеном в поддержании гомеостаза и, в частности, при патологии предстательной железы, предопределяет включение в комплексное лечение средств антиоксидантного действия. Перспективным можно считать применение препаратов с высоким содержанием биофлавоноидов и антиоксидантных витаминов. Включение в комплексное лечение таких пациентов препарата Кверцетина приводит к сокращению сроков нормализации клинико-лабораторных проявлений заболевания благодаря восстановлению равновесия между перекисным окислением липидов и состоянием антиоксидантной системы защиты Despite the successes achieved in the diagnosis and treatment, to date, the problem of chronic progression in patients with benign hyperplasia of the growth continues to remain relevant. Meanwhile, recovery or persistent remission of chronic prostatitis occurs only in 30-35% of patients who receive traditional treatment. In the pathogenesis of chronic prostatitis, membrane-pathological processes take an important place, which are caused by the activation of lipid peroxidation and impaired state of the antioxidant defense system. In patients with chronic prostate and benign hyperplasia, a significant increase in lipoperoxidation processes is observed against the background of a reduced functional ability of antioxidant defense systems. Therefore, the equilibrium in the oxidant-antioxidant system is an important link in the maintenance of homeostasis and, in particular, with the pathology of the prostate gland, allows the inclusion of antioxidant drugs in the complex treatment. The use of drugs with a high content of bioflavonoids and antioxidant vitamins can be considered promising. The inclusion of such patients in the complex treatment of the drug Quercetin leads to a reduction in the normalization period of the clinical and laboratory manifestations of the disease due to the restoration of the equilibrium between the peroxidation of the lipid peroxidation system and the state of lipid peroxidation

scholarly journals P104 Management of Chronic Prostatitis in an Inner London Sexual Health Clinic

2016 ◽  
Vol 92 (Suppl 1) ◽  
pp. A55.2-A55
Author(s):  
Mohamed Abdulcadir ◽  
Rosemarie Turner ◽  
Temi Lampejo
Keyword(s):  
Sexual Health ◽  
Chronic Prostatitis ◽  
Health Clinic

The Status of Microvascular Reactivity in Infertile and Fertile Patients with Chronic Prostatitis

2015 ◽  
Vol 22 (4) ◽  
pp. 68-73
Author(s):  
Полунин ◽  
A. Polunin ◽  
Садретдинов ◽  
R. Sadretdinov ◽  
Воронина ◽  
...  
Keyword(s):  
Sodium Nitroprusside ◽  
Chronic Prostatitis ◽  
Prostate Gland ◽  
Control Group ◽  
Doppler Flowmetry ◽  
Microvascular Response ◽  
The Status ◽  
Patient Groups ◽  
Tonic Stimulation ◽  
Infertile Patients

The study covered 280 patients with chronic prostatitis (CP) on the background of sexually transmitted infections. Patients with chronic prostatitis were divided into 2 patient groups: infertile males (140) and fertile males (140). The control group consisted of 50 somatically healthy males of a reproductive age. To assess the functional state of skin microvessels in the projection of the prostate gland, the authors used the method of laser Doppler flowmetry supplemented by iontophoretic probes with sodium nitroprusside and acetylcholine. It has been proved that the development of infertility in patients with chronic prostatitis is associated with a number of microvascular disorders. In the infertile male group with chronic prostatitis the authors observed a marked inflammatory hyperemia and a decrease in the microvascular response to a sympathetic and tonic stimulation. Not only was the direct microvascular vasodilation under the influence of sodium nitroprusside reduced, but the production of their own vasodilators under the influence of acetylcholine as well, indicating the development of endothelial dysfunction. The peculiarity of the microvascular endothelial reaction to iontophoresis of endothelium‐dependent vasodilator (acetylcholine) in the infertile patients with chronic prostatitis was the slowdown of the development of vasodilation with its quicker cessation, unlike the fertile patients who, on the contrary, developed vasodilation faster than the control group.

scholarly journals APPLICATION OF “PROXELAN” SUPPOSITORY IN TREATMENT OF SYMPTOMS OF LOWER URINARY WAYS ASSOCIATED WITH CHRONIC PROSTATITE AND BENIGN HYPERPLASIA OF THE PROSTATE GLAND

2018 ◽  
pp. 46-51
Author(s):  
Юрий Заседа
Keyword(s):  
Urinary Tract ◽  
Treatment Regimen ◽  
Lower Urinary Tract ◽  
Prostate Gland ◽  
Study Groups ◽  
Health Clinic ◽  
Treatment Groups ◽  
High Prevalence ◽  
Rectal Suppositories ◽  
Lower Urinary

Relevance. Symptoms of the lower urinary tract take a central role in outpatient urology, primarily due to the high prevalence in the general population.Objective: To analyze the eff ectiveness of suppositories “Proxelan” in the treatment of symptoms of the lower urinary tract associated with chronic prostatitis and benign prostatic hyperplasia of the mild degree.Design. The study was conducted in a prospective design on a contingent of 100 male patients who underwent outpatient treatment at the “Men’s Health Clinic” LLC. Patients were divided into 2 groups, depending on the presence in the treatment regimen of rectal suppositories “Proxelan”.Results of the study. The fi ndings on the diff erences in the intensity of symptom manifestations in the structure of lower urinary tract symptoms, according to the I-PSS scale, indicate that there is a signifi cant clinical eff ect on the symptoms in general for both treatment groups. Diff erences between the eff ect in the study groups range from moderate to minor.Conclusions. It has been established that the inclusion in the treatment regimen of rectal suppositories “Proxelan” allows to increase the clinical eff ect with respect to some indicators, namely: frequent urination and weakening of the urine stream. In addition, signifi cantly improve the quality of life of patients with symptoms of the lower urinary tract.

Shock-Wave Therapy in the Treatment of the Patients with Chronic Prostatitis and Erectile Dysfunction

10.12737/2904 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-10
Author(s):  
Неделько ◽  
D. Nedelko ◽  
Лазарев ◽  
I. Lazarev
Keyword(s):  
Shock Wave ◽  
Erectile Dysfunction ◽  
Chronic Prostatitis ◽  
Prostate Gland ◽  
Clinical Effects ◽  
Shock Wave Therapy ◽  
Antibacterial Effects ◽  
Pathogenetic Therapy ◽  
Methods Of Treatment ◽  
Stimulation Of

Despite numerous methods of treatment, the therapeutic efficiency of erectile dysfunction in the patients with chronic prostatitis is 45-56%, due to the fact that pharmacological preparations in a greater percentage of cases don´t penetrate into the prostate gland and cause side effects. Therefore, some researchers suggest the use of physiotherapy. Currently, highly effective method of treatment of erectile dysfunction in the patients with chronic prostatitis is a shock-wave therapy, the main clinical effects which are analgesic effect, activating microcirculation and neo-angiogenesis, stimulation of metabolic processes, reducing the severity of fibro-sclerotic changes, anti-inflammatory and antibacterial effects. The authors aim of the study is pathogenetically justify the use of the shock-wave therapy of erectile dysfunction in patients with chronic prostatitis with the positions of system-structural analysis. The study involved 40 patients with chronic prostatitis with erectile dysfunction. On the basis of these studies the authors have shown that the shock- wave therapy is the pathogenetic therapy of chronic prostatitis, as has a direct effect on the prostate gland and vasodilator effect, reduces edema, leukocyte infiltration.

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