scholarly journals EXPERIENCE OF USE OF OFOR AND GYNEKIT IN THE TREATMENT OF PROSTATITIS ASSOCIATED WITH SPECIFIC AND MIXED MICROBIAL FLORA

2017 ◽  
pp. 39-43
Author(s):  
Юрий Заседа ◽  
Фарид Шыхалиев ◽  
Руслан Соломенный
Keyword(s):  
Prospective Study ◽  
Trichomonas Vaginalis ◽  
Prostate Gland ◽  
Microbial Flora ◽  
Health Clinic ◽  
Sonographic Examination ◽  
Clinical Recovery ◽  
Combined Application ◽  
Pcr Method ◽  
Therapeutic Model

Purpose of the study – establish the eff ectiveness of «Ofor» and «Gynekit» use in sequential combined application in the therapy of prostate gland infl ammatory diseases, which associated with a specifi c and mixed microbial flora.Materials and methods. A clinical prospective study was conducted, 30 patience of outpatient department of the «Men’s Health» clinic, suff ering from infl ammatory diseases of the prostate gland, took part in it. As methods of research, in addition to standard complex, the following were chosen: IN POUCH TV-test; Androfl or (PCR method); sonographic examination of the prostate and spermogram. Results of the study. The study found that in the general contingent clinical recovery was registered in 29 patients (96.7% of the total contingent), laboratory – in 27 cases (90% of the total contingent). The return of symptoms in 3 months was registered in 2 patients (6.7% of the total contingent).Conclusions. The level of eff ectiveness of “Ofor” and “Gynekit” use in combination with a set of auxiliary pharmaco and physiotherapy for patients, who suff ering from infl ammatory diseases of the prostate gland, associated with specifi c and mixed microbial fl ora, reaches 96.7%. Analysis of the etiological variability of the clinical eff ect indicates the presence of single cases of incomplete eff ect of this therapeutic model, with the etiology of the disease associated with Trichomonas vaginalis.

scholarly journals EXPERIENCE OF NIFURATEL USAGE IN COMPLEX TREATMENT OF CHRONIC SPECIFIC BACTERIAL FIBROUSE AND CALCULOUS PROSTATITIS ASSOCIATED WITH TRICHOMONIASIS AND CANDIDOSIS

2018 ◽  
pp. 33-37
Author(s):  
Юрий Заседа
Keyword(s):  
Oral Administration ◽  
Mixed Infection ◽  
Trichomonas Vaginalis ◽  
Infectious Agents ◽  
Complex Treatment ◽  
Total Dosage ◽  
Candida Spp ◽  
Sonographic Examination ◽  
Pcr Method ◽  
Therapeutic Model

The aim of the study was to analyze the effi cacy of the drug “Macmiror” (active substance – nifuratel) in the treatment of chronic specifi c bacterial fi brous and calculous prostatitis associated with trichomoniasis and candidiasis.Materials and methods. The study was conducted on 50 patients of the “Clinic “Men’s Health”, suff ering from chronic specifi c bacterial fi brous and calculous prostatitis (mixed infection: trichomonadial-bacterial-candidiasis associates of various structure). As methods of research, in addition to the standard complex, the following were chosen: IN POUCH TV-test; PCR method; sonographic examination ofthe prostate and spermogram.Results of the study. Patients who completed the study were treated with chronic specifi c bacterial fi brous and calculous prostatitis (N41.1) for 14 days, according to the following therapeutic model: oral administration of nifuratel as part of the “Macmiror” preparation at a total dosage of 1200 mg per day (6 tablets of 200 mg) divided into 3 doses and physiotherapy.Conclusions. A general (in relation to diff erent types and combinations of infectious agents) of the therapeutic model has been established at a level of 71% to 100%. Treatment had absolute (clinical and laboratory) effi cacy against isolated Candida spp.; absolute clinical effi cacy and 71-85% laboratory effi cacy against isolated Trichomonas vaginalis; 92% clinical and 76-84% laboratory effi cacy against the combination of these infectious agents; 92% clinical and 80% laboratory effi cacy against the combination of these infectious agents and non-specifi c bacterial fl ora, as the etiological factors of chronic specifi c bacterial prostatitis.

scholarly journals THE ANALYSIS OF EFFICACY OF “CEFPOTEC” AND “CLABEL” PREPARATIONS IN TREATMENT OF SPECIFIC AND NONSPECIFIC PROSTATITIS

2019 ◽  
pp. 44-50
Author(s):  
Юрий Заседа
Keyword(s):  
Oral Administration ◽  
Chronic Prostatitis ◽  
Prostate Gland ◽  
Health Clinic ◽  
Mixed Infections ◽  
Infectious Agents ◽  
Bacteriological Examination ◽  
Prospective Design ◽  
Sonographic Examination ◽  
Pcr Diagnostics

Objective: to establish the eff ectiveness of Сefpotek (cefpodoxime) and Сlabel (clarithromycin) drugs in the treatment of chronic prostate infl ammation in the stage of pronounced exacerbation caused by nonspecifi c infectious agents and infections of the mycoplasma and chlamydia groups.Materials and methods. The study was conducted in a prospective design on parallel groups. The study contingent consisted of 60 patients of the “Men’s Health Clinic”, suff ering from chronic prostatitis in state of pronounced exacerbation. The following research methods were used: sonographic examination of the prostate gland, bacteriological examination of the ejaculate, analysis of ejaculate and PCR diagnostics of specifi c infections.The results of the study. A diff erentiated course of etiotropic therapy was carried out. In case of non-specifi c prostatitis: oral administration of the drug “Cefpotek” (cefpodoxim) 1 tablet (200 mg) 2 times a day for a course of 14 days with the possibility of extending the course to 28 days. With specifi c prostatitis: oral administration of the drug “Clabel” (clarithromycin) 1 tablet (500 mg) 2 times a day for a course of 14 days.Conclusions. In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by nonspecifi c infectious agents using oral administration of the drug “Сefpotek”, the full eff ectiveness was achieved in range from 83.3% to 96.6% of observations.In the treatment of chronic infl ammation of the prostate gland in the stage of pronounced exacerbation caused by infectious agents of the mycoplasma and chlamydia groups using oral administration of the drug “Clabel”, the full eff ectiveness was achieved in the range from 80.0% to 86.6% of observations (regardless of features of combinations of specifi c mixed infections).

scholarly journals Treatment of genital invasions caused by Trichomonas vaginalis, Trichomonas tenax, Pentatrichomonas hominis, G. lamblia

2019 ◽  
pp. 5-10 ◽  
Author(s):  
Павел Федорич ◽  
Геннадий Мавров
Keyword(s):  
Trichomonas Vaginalis ◽  
Treatment Method ◽  
Genitourinary System ◽  
Clinical Recovery ◽  
Pcr Method ◽  
Pentatrichomonas Hominis

Objective. The study of the prevalence and clinical man­ifestations of T. tenax, P. hominis, along with T. vagina­lis and G. lamblia invasions among patients with STIs, and development of their treatment method with the use of secnidazole, ornidazole and ciprofloxacin. Materials and methods. With the help of the PCR method, 314 patients with inflammation of the genitourinary system have been studied. Results and discussion. The geni­tourinary system protozoan invasions have been detect­ed in 106 patients among 314 patients with STIs - that is, more than in a third (33.8 %), namely: T. tenax - in 26 (8.3 %), P. hominis - in 67 (21.3 %), G. lamblia - in 21 patients (6.7 %). The proposed treatment allows for the clinical recovery in 92.2 % and bacteriological sanita­tion - in 96.1 %. Conclusions: Protozoan invasions are rather common among patients with STIs. The proposed method of their treatment is sufficiently effective.

Pathologic findings in prostate gland at autopsy with topographic distribution of these diseases within the prostatic zones: Eleven-month prospective study in Oauthc, Ile-Ife, Nigeria

2020 ◽  
Vol 9 (16) ◽  
pp. 44
Author(s):  
IfeomaFlorence Ezejiofor ◽  
WilliamsOlufemi Odesanmi ◽  
OluwoleOlaniyi Odujoko ◽  
AkinwumiOluagbenga Komolaefe ◽  
TosinO Alade ◽  
...  
Keyword(s):  
Prospective Study ◽  
Prostate Gland ◽  
Pathologic Findings ◽  
Topographic Distribution

scholarly journals Trichomonas vaginalis infection is uncommon in the British general population: implications for clinical testing and public health screening

2016 ◽  
Vol 94 (3) ◽  
pp. 226-229 ◽  
Author(s):  
Nigel Field ◽  
Soazig Clifton ◽  
Sarah Alexander ◽  
Catherine A Ison ◽  
Rumena Khanom ◽  
...  
Keyword(s):  
General Population ◽  
Trichomonas Vaginalis ◽  
Population Data ◽  
Sample Survey ◽  
Health Clinic ◽  
Clinic Attendance ◽  
Molecular Tests ◽  
Public Health Screening ◽  
History Of ◽  
Mixed Ethnicity

IntroductionVariable use of new molecular assays, asymptomatic infections and a lack of population data mean that the population burden of Trichomonas vaginalis is uncertain. We investigated the age-specific prevalence of T. vaginalis within the sexually active British general population to inform testing strategies.MethodsBritain's third National Survey of Sexual Attitudes and Lifestyle (Natsal-3) is a probability sample survey of 15 162 individuals aged 16–74 years, undertaken during 2010–2012. Urine from 4386 participants aged 16–44 years reporting ≥1 lifetime sexual partner was tested for T. vaginalis using in-house real-time PCR.ResultsUrinary T. vaginalis was detected in seven women and no men providing urine samples, giving a weighted prevalence estimate of 0.3% (95% CI 0.1% to 0.5%) in sexually experienced women aged 16–44 years. Of the seven women with T. vaginalis detected, four were of black or mixed ethnicity (prevalence 2.7% (0.9% to 7.7%) in this group) and five reported recent partners of black or mixed ethnicity. Six of the women reported symptoms, and five reported sexual health clinic attendance in the past 5 years (prevalence in those reporting clinic attendance: 1.0% (0.4% to 2.3%)). The prevalence of a self-reported history of T. vaginalis (past 5 years) was 0.1% (0.0% to 0.2%) in women and 0.0% (0.0% to 0.2%) in men aged 16–44 years.ConclusionsOur British population prevalence estimates indicate that T. vaginalis is a rare infection. These data support policies that restrict asymptomatic screening for T. vaginalis and suggest deployment of molecular tests should be focused within clinical settings and guided by symptoms and local demography.

Cervicitis: limited clinical utility for the detection of Mycoplasma genitalium in a cross-sectional study of women attending a New Zealand sexual health clinic

Sexual Health ◽  
2013 ◽  
Vol 10 (3) ◽  
pp. 263 ◽  
Author(s):  
Jeannie Oliphant ◽  
Sunita Azariah
Keyword(s):  
Sexual Health ◽  
Trichomonas Vaginalis ◽  
Clinical Utility ◽  
Clinical Symptoms ◽  
Mycoplasma Genitalium ◽  
Cross Sectional Study ◽  
Health Clinic ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sexually Transmissible Infections

Background Although multiple studies have confirmed Mycoplasma genitalium as a cause of nongonococcal urethritis in men, there is less evidence of its pathogenicity in women. Our aims were to determine the prevalence of M. genitalium in a sample of women attending a sexual health clinic and to assess whether there was any association between the detection of M. genitalium and a diagnosis of cervicitis in this population. Methods: A cross-sectional study recruited women who required screening for sexually transmissible infections. Endocervical swabs to detect the presence of M. genitalium were taken in addition to routine testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis. Data were collected on demographics, sexual behaviour, clinical symptoms and the presence of clinical or microscopic cervicitis. Results: The prevalence of M. genitalium was 8.4% (n = 22, 95% confidence interval (CI): 5.4–12.5%) in the study sample of 261 women. There was an association between the finding of cervical contact bleeding (odds ratio OR): 5.45; 95% CI: 1.93–15.42, P = 0.001) and microscopic cervicitis (OR: 2.64; 95% CI: 0.95–7.34, P = 0.06) and the presence of M. genitalium when compared with women with no diagnosed infection; however, the latter finding was not statistically significant. Conclusions: Although the prevalence of M. genitalium was high at 8.4%, the overall lack of any association between the findings of cervicitis and the detection of M. genitalium support the conclusion that cervicitis has poor clinical utility as an indicator for the presence of M. genitalium infection.

scholarly journals APPLICATION OF “PROXELAN” SUPPOSITORY IN TREATMENT OF SYMPTOMS OF LOWER URINARY WAYS ASSOCIATED WITH CHRONIC PROSTATITE AND BENIGN HYPERPLASIA OF THE PROSTATE GLAND

2018 ◽  
pp. 46-51
Author(s):  
Юрий Заседа
Keyword(s):  
Urinary Tract ◽  
Treatment Regimen ◽  
Lower Urinary Tract ◽  
Prostate Gland ◽  
Study Groups ◽  
Health Clinic ◽  
Treatment Groups ◽  
High Prevalence ◽  
Rectal Suppositories ◽  
Lower Urinary

Relevance. Symptoms of the lower urinary tract take a central role in outpatient urology, primarily due to the high prevalence in the general population.Objective: To analyze the eff ectiveness of suppositories “Proxelan” in the treatment of symptoms of the lower urinary tract associated with chronic prostatitis and benign prostatic hyperplasia of the mild degree.Design. The study was conducted in a prospective design on a contingent of 100 male patients who underwent outpatient treatment at the “Men’s Health Clinic” LLC. Patients were divided into 2 groups, depending on the presence in the treatment regimen of rectal suppositories “Proxelan”.Results of the study. The fi ndings on the diff erences in the intensity of symptom manifestations in the structure of lower urinary tract symptoms, according to the I-PSS scale, indicate that there is a signifi cant clinical eff ect on the symptoms in general for both treatment groups. Diff erences between the eff ect in the study groups range from moderate to minor.Conclusions. It has been established that the inclusion in the treatment regimen of rectal suppositories “Proxelan” allows to increase the clinical eff ect with respect to some indicators, namely: frequent urination and weakening of the urine stream. In addition, signifi cantly improve the quality of life of patients with symptoms of the lower urinary tract.

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