scholarly journals Clinical and Socio-Demographic Pattern of Beta Thalassaemia in Bangladesh

2020 ◽  
Vol 4 (1) ◽  
pp. 3-7
Author(s):  
Adnan Hasan Masud ◽  
Md. Kamrul Hasan ◽  
Saradindu Kanti Sinha ◽  
Kazi Mohammad Kamrul Islam ◽  
Md. Jalilur Rahman
Keyword(s):  
Tertiary Care ◽  
Cross Sectional ◽  
Female Ratio ◽  
Beta Thalassaemia ◽  
The Mean ◽  
Almost All ◽  
Hb Concentration ◽  
Medical University ◽  
Tertiary Care Hospitals ◽  
Male To Female

Beta thalassaemia is one of the most prevalent haemolytic disorders worldwide which poses serious economic burden to the society. Study on clinical and demographic pattern of this disorder will help the concern authorities to figure out the problem. This cross-sectional descriptive study was carried out to determine the socio-demographic and clinical characteristics as well as to find out the existence of other co-morbidities among the ?-thalassaemic patients (n-101). The study was carried out at the Department of Haematology, Bangabandhu Sheikh Mujib Medical University (BSMMU) from June 2010 to January 2011. Data were collected from 3 tertiary care hospitals of Dhaka city. Almost all the patients were young, age ranged from 10 to 32 years with the mean age of 16. Male to female ratio was almost equal (52.5:47.5) and 80% of the respondents were Muslims. Forty-five (45%) percent of patients were illiterate and 37% respondents had primary education only. Almost 90% were unmarried and majority had a family of 6-8 members. Forty-seven percent (47%) of patients had monthly income 5000-7000 BDT and 56% of the respondents were unemployed. The major clinical features were pallor (72.3%), palpitation (60%), and breathlessness (52.5%). The haemoglobin (Hb) concentration ranged from 7gm/dl to 12gm/dl and 57% patients had an Hb concentration of 8 gm/dl. Sixty percent of the respondents had jaundice with majority had enlarged spleen (86%) and some had enlarged liver too (23%). Ninety percent (90%) respondents had co-morbidities among which arrhythmia is more prevalent (54%).

scholarly journals Accidental childhood poisoning in Paediatrics department of a tertiary care facility: A retrospective review

2020 ◽  
Vol 47 (3) ◽  
Author(s):  
D.C. Obu ◽  
M.C. Orji ◽  
U.V. Muoneke ◽  
U.V. Asiegbu ◽  
G.O. Ezegbe
Keyword(s):  
Tertiary Care ◽  
Care Facility ◽  
Accidental Poisoning ◽  
Female Ratio ◽  
The Public ◽  
Tertiary Care Facility ◽  
Childhood Poisoning ◽  
The Mean ◽  
The Relationship ◽  
Male To Female

Background: Accidental childhood poisoning is a recognized preventable cause of morbidity and mortality among children worldwide. This studywas aimed at determining the prevalence, pattern, and outcome of childhood poisoning among children in Abakaliki, Ebonyi State. Material and Methods: Medical records of all cases of accidental childhood poisoning admitted into Children’s emergency room (CHER) of the health facility of study between January 2014 and December 2018 were retrospectively identified and relevant data extracted and analyzed usingSPSS version 22. Results: Out of the 7,700 children that presented to CHER over a 5- year period, 42 were cases of poisoning, giving prevalence rate of 0.5%. Of the 42 cases, only 20 case notes were retrieved. The male to female ratio was 2.3:1 while the ages ranged between 6months and 14 years with the mean age of 3.06±2.88. Kerosene poisoning had the highest proportion of 50.0% (10/20) with the overall mortality rate of 5.0% (1/20).The relationship between age, place of residence and outcome in poisoned children was statistically significant (p = 0.038, 0.045 respectively). Conclusion: Accidental childhood poisoning is common in Abakaliki. Kerosene still remained the major agent while male toddlers were most  vulnerable. There is need to intensify enlightenment campaigns and education of the public about the hazard of improper storage of kerosene and other implicated substances at home. Keywords: Accidental poisoning, Childhood, Kerosene

scholarly journals Clinical Spectrum and Neuroimaging Changes in Neurodegenerative Disorder-Experiences in Tertiary Care Hospital of Bangladesh

2021 ◽  
Vol 2 (6) ◽  
pp. 10-14
Author(s):  
Gopen Kumar Kundu ◽  
Rumana Islam ◽  
Noor E-Sabah ◽  
ABM Mukib
Keyword(s):  
Neurodegenerative Diseases ◽  
Tertiary Care Hospital ◽  
Neurodegenerative Disorder ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Care Hospital ◽  
Female Ratio ◽  
History Of ◽  
The Mean ◽  
Male To Female

Neurodegenerative diseases (NDD) are a heterogeneous group of disorders characterized by progressive loss of previously acquired skills that are of varied etiology, clinical manifestations, and natural course. There is a paucity of data on clinical profile of neurodegenerative diseases in our population. We conducted a retrospective study with 68 diagnosed cases of NDD at a tertiary care hospital in Bangladesh. Among them, more than one-third of children were in 1-5 years age group. The mean age was 10.2±3.1 year and male to female ratio was 2:1. Fifty percent of cases had a history of consanguineous parents. Leukodystrophy was most common (30.88%) among NDDs, followed by Wilson disease (26.47), SSPE (22.1%), and Degenerative Ataxia (20.59%). Motor skill regression was the most common presentation (97%), followed by speech regression in 91% and Gait disorder in 83% of children. Seizure was presenting features in 24% of children. Neuroimaging abnormalities were found in 80.88% NDD cases. Among them white matter hyper intensity in 29.41%, cerabeller atrophy in 13.25 %, and cerebral atropy in 11.76% of children. Eye changes were found in about two-thirds (69.12%) of cases of NDD. Among them, optic atrophy was found in 29.41%, and KF rings in 25.00% of cases.

scholarly journals Profile of Secondary Glaucoma in a Tertiary Eye Hospital of Eastern Nepal

2021 ◽  
Vol 13 (1) ◽  
pp. 98-103
Author(s):  
Jamuna Gurung ◽  
Rakshya Pant Sitoula ◽  
Anjani Kumar Singh
Keyword(s):  
Optic Atrophy ◽  
Cross Sectional Study ◽  
Secondary Glaucoma ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Poor Vision ◽  
Post Traumatic ◽  
The Mean ◽  
Male To Female

Background: To determine the clinical profile and causes of various types of secondary glaucoma. Materials and methods : This was a hospital-based cross-sectional study conducted in a tertiary eye hospital of eastern Nepal from 1st June to 30th November, 2017. Patients who met the criteria for secondary glaucoma underwent detailed ophthalmic examination. Results : Out of 7079 patients diagnosed with glaucoma or glaucoma suspects, 528 (7.4%) had secondary glaucoma. The mean age at presentation was 52 ± 17 years with male to female ratio of 1.5:1. The most common cause was lens induced 173 (32.8%) followed by neovascular 107 (20.3%), steroid induced 86 (16.3%), traumatic 76 (14.4%), post-vitrectomy 17 (3.2%), uveitic 11 (2.1%), pseudophakic 10 (1.9%), aphakic 8 (1.5%), post-keratoplasty 5 (0.9%) and miscellaneous included 35 (6.6%). Post-traumatic 31 (29.5%) was more prevalent below 41 years while lens induced glaucoma 86 (49%) above 60 years of age. At presentation, the average IOP was 40 ± 11 mmHg. 36 (6.8%) had no light perception in the presenting eye and a large number of participants 307 (58.1%) presented with visual acuity of <3/60 to perception of light. Glaucomatous optic atrophy was found in 22 (9.0%) cases.  Conclusion : The causes of secondary glaucoma are diverse, lens induced glaucoma being most common. Most patients present late with poor vision, high IOP and even glaucomatous optic atrophy. So, early identification and treatment of the causes is important so that we can prevent the burden of blindness due to secondary glaucoma.

scholarly journals Spectrum of Different Spinal Disorders Presenting to Neurosurgical Department of Public Sector Tertiary Care Hospitals of Peshawar

2019 ◽  
Vol 23 (4) ◽  
Author(s):  
ADNAN AHMED ◽  
MOHAMMAD ISHAQ ◽  
MUMTAZ ALI ◽  
MUSAWER KHAN ◽  
SOHAIL AHMAD ◽  
...  
Keyword(s):  
Public Sector ◽  
Tertiary Care ◽  
Neurosurgical Department ◽  
Female Ratio ◽  
Spinal Disorders ◽  
And Gender ◽  
Age Range ◽  
Tertiary Care Hospitals ◽  
Male To Female

Objectives: To assess the spectrum of different spinal disorders presenting to the Neurosurgical department of public sector tertiary care hospitals of Peshawar.Materials and Methods: This was a retrospective study carried out in the Neurosurgery departments of two public sector tertiary care hospitals in district Peshawar from January 2012 to December 2018. Our inclusion criteria comprised of all those patients who were having spinal abnormalities irrespective of age and gender, admitted either via emergency or OPD. We excluded those patients who were dead on arrival or whose data was lacking including those who did not do their follow up and those who were not given consent for the study.Results: Out of total 5,579 patients, male to female ratio was 1:1.7. The age range was from 6 days to 78 years. Elective cases were 63.61% (n = 3,549) and emergency were 36.37% (n = 2,030). TSCI were 35.01% (n = 1,953) and NTSCI were 3,626 (n = 64.99%). Out of all patients, 91.03% (n = 5,079) were treated surgically. About 79% (n = 4,406) had a good outcome.Conclusion: We collected data and made a survey of the spectrum of different spinal abnormalities resulting from various etiologies focused over the last 6 years. We found a variety of cases presenting to our departments of neurosurgery. Non traumatic spinal injuries are more frequent as compared to traumatic ones.

scholarly journals Psychological Implications of The Late Phase of COVID-19 Pandemic among Medical Undergraduates, Attending Clinical Wards Rotations in Tertiary Care Hospitals of Rawalpindi, Pakistan: An Online Survey-Based Study

2020 ◽  
Vol 2 (5) ◽  
Author(s):  
Arham Ihtesham ◽  
Ather Iqbal ◽  
Muhammad Sarfraz Khan ◽  
Ali Murad Jamal ◽  
Shahzaib Maqbool ◽  
...  
Keyword(s):  
Health Care Professionals ◽  
Online Survey ◽  
Late Phase ◽  
Tertiary Care ◽  
Family Members ◽  
Predisposing Factors ◽  
Cross Sectional ◽  
Medical Undergraduates ◽  
The Mean ◽  
Tertiary Care Hospitals

  COVID-19 is proving to be a double-edged sword for health care professionals. It is not only causing physical malfunctioning but mental suffering among medical undergraduates. This study demonstrates the psychological impact and various predisposing factors causing mental distress. This is a descriptive cross-sectional study involving 157 medical undergraduates of Third, Fourth, and Final year MBBS being trained in tertiary care hospitals of Rawalpindi, Pakistan in September 2020, when the graph of COVID-19 was flattening. Data was collected through a self-designed questionnaire for demographic details and DASS-21. The mean and standard deviation was calculated for depression, anxiety, and stress levels. Frequencies and percentages were calculated for the severity of DASS-21 and predisposing factors. Data analysis was done through SPSS. V. 25. Out of 157 students, there were 80(51%) males and 77 (49%) females. The mean age was 22.52 (SD=1.60). The overall mean score of anxiety was 7.43 ± 4.53, depression was 7.75 ± 4.12, and stress was 8.15 ± 4.53. This study found that the most common reason for stress and anxiety among students attending wards was the fear that they might infect their family members 42 (26.8%), followed by the fear of getting infected themselves 39 (24.8%). This study doesn’t exhibit a significant mental burden of grave concern however, the anxiety level was high among the Third year and depression level was high among Final year students. Fear of infecting family members and contracting the virus themselves were common reasons for distress.  

scholarly journals Serum Lead Level and Polyneuropathy among Bangladeshi Patients

2015 ◽  
Vol 31 (2) ◽  
pp. 65-69
Author(s):  
Swapon Kumar Ghose ◽  
Kazi Gias Uddin Ahmed ◽  
Ahmed Hossian Chowdhury ◽  
ATM Hasibul Hasan ◽  
Kanol Saha ◽  
...  
Keyword(s):  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
Acute Type ◽  
Female Ratio ◽  
Acute Polyneuropathy ◽  
The Mean ◽  
The Difference ◽  
Medical University ◽  
Male To Female

Background: Heavy metals may produce various symptoms among the exposed, of which polyneuropathy is a matter of real concern. Our aim was to determine the pattern and association between polyneuropathy and blood lead level. Methods: This case control study was done in the department of Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka in collaboration with Bangladesh Atomic Energy Centre from July 2001 to June 2002. The lead concentration in the blood was detected by Xray fluorescence (XRF) technique. Nerve conduction study and CSF examination were done among the cases. Result: Data were collected from 92 respondents, of whom cases and controls were equal in number with a male to female ratio of 8.17:1. Mean age of the cases and controls were 30.87 +14.53 years and 30.91+ 12.03 years respectively. Among the cases, 55% had sub acute type of polyneuropathy, followed by acute and chronic type of polyneuropathy among 30% and 15% respondants respectively. The mean CSF protein level was 112.00 + 65.04 gm/L. The mean CSF protein was higher in acute polyneuropathy than in subacute and chronic cases (p<.001). The mean blood lead level among cases was 45.5587 with a standard deviation (SD) of +35.2625 and among control were 33.2065 with a SD of +5.6793. The difference was statistically significant (p= 0.021). Bangladesh Journal of Neuroscience 2015; Vol. 31 (2): 65-69

scholarly journals Sensitivity of electroencephalogram in the diagnosis of epilepsy among patients attending a neuropsychiatric hospital in Northern Nigeria

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Shehu Sale
Keyword(s):  
High Sensitivity ◽  
Epileptic Seizures ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Future Studies ◽  
Duration Of Illness ◽  
The Mean ◽  
Male To Female ◽  
Ethical Clearance

Electroencephalography (EEG) is an essential adjunct in management of epilepsy. While some studies reported that EEG has a high sensitivity in detecting epileptic seizures, others disagree. Therefore, it is important to know sensitivity of this important procedure in our setting. This was a cross-sectional study carried out from 2015 to 2018. Participants were patients attending the outpatient clinic of a psychiatric hospital to achieve care for epileptic seizures. Ethical clearance was obtained prior to the conduct of this study. In addition, informed consent was obtained from each patient or their caregivers. Data analysis was done using SPSS version 20. The study involved 177 participants aged 2-70 years (median = 17 years). The male to female ratio was 2:1. The mean duration of illness was 7.8±5.8 (range = 1-35 years). Sensitivity of EEG was 70.6%. There was no difference between either age, gender or duration of illness and probability of having an abnormal EEG. EEG is sensitive in the diagnosis of epilepsy in our setting. Future studies should focus on factors influencing sensitivity of EEG in diagnosis of epilepsy.

scholarly journals Spirometric evaluation in patients with allergic rhinitis- emphasising need of early diagnosis: a tertiary care experience from Central India

2018 ◽  
Vol 5 (6) ◽  
pp. 1460
Author(s):  
Nilesh S. Sonawane ◽  
Sanjay M. Gour ◽  
Radha P. Munje ◽  
Vandana P. B.
Keyword(s):  
Allergic Rhinitis ◽  
Tertiary Care ◽  
Central India ◽  
Clinical History ◽  
Cross Sectional ◽  
Female Ratio ◽  
Bronchodilator Therapy ◽  
Care Experience ◽  
Sputum Eosinophilia ◽  
The Mean

Background: Allergic rhinitis is predecessor of Bronchial asthma in most of the cases. Present study was aimed to understand the prevalence of the impaired spirometric changes in patients with allergic rhinitis and to find association with various demographic factors, sputum eosinophilia and eosinophil count in the blood with the impaired Spirometry of these patients.Methods: Authors conducted a cross sectional study among the patients of allergic rhinitis presented to us in our outpatient department from January 2016 to July 2017. The patient’s with allergic rhinitis either newly diagnosed or already on treatment were included in the study. Standard guidelines as given by ARIA were followed in defining a case of allergic rhinitis. The detailed clinical history was taken, and examination was performed of all the patients and documented. Spirometric evaluation was done using the standard guidelines by a desktop based Spirometry.Results: The mean age of the study subjects was 30.22±13.13 years with male: female ratio of 0.96. The mean duration of the allergic rhinitis in our study was 3.86±3.34years. The most common complaint was itching sensation of nose followed by paroxysmal sneezing and watering of eyes. About 22.15% of the study subjects have impaired Spirometry. Upon bronchodilator therapy 30% of the study subjects had significant reversibility in FEV1.Conclusions: About ¼ of present study subjects had impaired Spirometry and about 30% of them had reversibility after bronchodilator therapy. Authors also found that the higher age study subjects had significantly higher impaired Spirometry; persistent allergic rhinitis patients had higher impairment of Spirometry and the patients with higher the sputum eosinophilia had higher impairment in Spirometry.

scholarly journals Comorbidity of COVID-19 related Fatalities in Tertiary Care Hospitals of Rawalpindi, Pakistan

2020 ◽  
Vol 24 (Supp-1) ◽  
pp. 32-36
Author(s):  
Rizwana Shahid ◽  
Muhammad Umar ◽  
Raja Bilal Zafar ◽  
Shazia Zeb ◽  
Saima Ambreen ◽  
...  
Keyword(s):  
Critical Illness ◽  
Hospital Stay ◽  
Tertiary Care ◽  
Length Of Hospital Stay ◽  
Hospital Data ◽  
Ventilator Support ◽  
Adverse Health Outcomes ◽  
The Mean ◽  
Medical University ◽  
Tertiary Care Hospitals

Objectives: To assess the COVID-19 associated fatalities with respect to demographics, comorbidity, critical illness, and length of hospital stay in tertiary care hospitals. Subjects & Methods: A retrospective hospital data-based research was done among 216 COVID-19 associated mortalities registered in 4 tertiary care hospitals Holy Family Hospital (HFH), Benazir Bhutto Hospital (BBH), District Head Quarters Hospital (DHQ) and Rawalpindi Institute of Urology & Transplantation (RIU & T) affiliated with Rawalpindi Medical University from 29th March-15th June 2020. The data was gathered by consecutive sampling pertinent to demographics, hospital stay, comorbidity, critical illness, and ventilator or oxygen support. The length of hospital stay among fatalities with and without comorbidity was compared by an independent sample z-test. Data were analyzed by using SPSS version 25.0. Results: Of the total 216 COVID-19 related mortalities, 150(69.4%) were males and 66(30.6%) were females. The mean age of fatalities was 55.66 ± 13.97 years. About 76.7% of dying males were 41-70 years old while 56.1% of females dying of COVID-19 were 41-60 years old. Most (60.8%) of study subjects had hypertension followed by diabetes (53.8%), Ischemic Heart Disease (17.5%), and respiratory disorders (12.3%). About 75% of the critically ill patients needed a ventilator for respiratory support. Length of hospital stay was determined to have a statistically insignificant association (P > 0.10) with the presence or absence of comorbidity among COVID-19 patients. Critical illness had a highly significant association (P < 0.000) with ventilator support among COVID-19 related mortalities. Conclusion: People 41-70 years should preferably adopt stringent precautions for protection against COVID-19. Comorbid states chiefly hypertension, diabetes, cardiac and respiratory diseases need special consideration amid COVID-19 pandemic to abstain from adverse health outcomes.

scholarly journals Frequency of paediatric facial trauma in a tertiary care dental hospital

2017 ◽  
Vol 5 (1) ◽  
pp. 310 ◽  
Author(s):  
Muhammad Athar Khan ◽  
Muhammad Ishfaq ◽  
Mobeen Akhtar ◽  
Sadiq Amin Ahmed Rana ◽  
Muhammad Kashif
Keyword(s):  
Tertiary Care ◽  
Facial Trauma ◽  
Facial Fracture ◽  
Facial Bones ◽  
Female Ratio ◽  
Dental Hospital ◽  
The Mean ◽  
Upper Third ◽  
Male To Female ◽  
Written Informed Consent

Background: The objective of the study was to determine the frequency of various patterns of pediatric facial trauma in the patients attending a tertiary care hospital.Methods: After written informed consent, 191 cases were taken using non- probability purposive sampling. Demographic profile (age, gender, address) was taken. Diagnoses of the distribution of facial fracture were made with help of history, clinical and radiological examination, plain radiographs, OPG (Orthopantomogram), Occipitomental, PA view of face and CT scan, according to the requirement. Pattern of facial trauma i.e. upper third of face (frontal bone, orbital bone), mid facial bones (Maxilla, Zygomatic, NOE noso-orbito-ethmodial complex), dentoalveolar and mandible was noted on the proforma attached. Data was entered and analysed using SPSS 20.0.Results: The mean age of the patients was 6.50±3.72 years. In this study, 112 (58.63%) were males and 79 (41.37%) were females. So, the male to female ratio were 1.41:1. The mandible was the most commonly fractured bone 58 (30.36%) followed by dentoalveolar, maxilla, zygomatic, NOE complex, orbital and frontal bones fractures.Conclusions: Mandible is the most prone to fracture in paediatric patients.

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