HUBUNGAN KEPATUHAN PENGGUNAAN OBAT ANTIDIABETES DENGAN KEBERHASILAN TERAPI PADA PASIEN DIABETES MELITUS TIPE 2 RAWATJALAN DI POLIKLINIK PENYAKIT DALAM RSUD EMBUNG FATIMAH BATAM 2018

2020 ◽  
Vol 9 (1) ◽  
pp. 1-9
Author(s):  
Bratasena Silalahi ◽  
Nopri Esmeralda
Keyword(s):  
Internal Medicine ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Univariate Analysis ◽  
The Body ◽  
Antidiabetic Drugs ◽  
Chi Square ◽  
Chi Square Analysis

Diabetes mellitus (DM) is a disease, with the condition that glucose levels in the blood exceed normal limits. This is because the body cannot release or use insulin adequately. Insulin is a hormone released by the pancreas and is the main substance responsible for maintaining blood sugar levels in the body to remain in a balanced condition. Insulin functions as a tool that helps sugar move into cells so that it can produce energy or be stored as energy reserves. The purpose of this study was to determine the Correlation between the Compliance of the Use of Antidiabetic Drugs and the Success of Therapy in Type 2 Diabetes Mellitus Patients Outpatient in the Internal Medicine Polyclinic of Embung Fatimah Hospital in Batam 2018.Method: This type of research is an observational analytic cross-sectional study design. The number of samples is 40 people. Data collection techniques by giving questionnaires about compliance and medical record data of patients with type 2 diabetes mellitus. Univariate analysis is presented in the frequency distribution table and bivariate analysis using chi-square with the SPSS system.Results: The results of a study with a sample of 40 patients, showed more than half of patients (62.5%), had high adherence and more than half of patients (62.5%), successful treatment success. Chi-Square analysis results obtained p.value = 0.041 where p is smaller than the significance level (α) = 5% (0.05). Ho rejected, which means there is a significant relationship between compliance with the use of antidiabetic drugs with the success of therapy in patients with type 2 diabetes mellitus outpatient in the Internal Medicine Polyclinic at Embung Fatimah Hospital in Batam 2018.Conclusion: Based on this study it was concluded that there was a Compliance Relationship between the Use of Antidiabetic Drugs and the Success of Therapy in Type 2 Diabetes Mellitus Patients Outpatient in the Internal Medicine Polyclinic at Embung Fatimah Hospital in Batam 2018.

scholarly journals TYPE 2 DIABETES MELLITUS ON TRIGLYCERIDE LEVELS AND BLOOD PRESSURE

2019 ◽  
Vol 1 (1) ◽  
pp. 11-16
Author(s):  
Wirawan Anggorotomo ◽  
Tessa Sjahriani ◽  
Masroni Masroni
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Frequency Distribution ◽  
Metabolic Diseases ◽  
P Value ◽  
Chi Square ◽  
Chi Square Analysis

Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by an abnormality of insulin secretion, insulin work, or both. DM cases in Indonesia as many as 8,5 million cases in 2013. Prevalence based on diagnosis or symptoms according to the health departement of 2,1%.Purpose: To know the correlation of type 2 diabetes mellitus on triglyceride levels and blood pressureMethods: This study used secondary data derived from the medical record status of patients with diabetes mellitus. The method used is analytic observational with cross sectional approach. Sampling technique using purposive sampling. The population of this study is the diabetes mellitus type 2 in 2017 as many as 151. Sample of 109 respondents. Data analyzed by univariate and bivariate using Chi Square analysis.Results: The frequency of respondent characteristic on female gender as much 57,8%, based on age group >45 old counted 58,7%. Blood pressure frequency distribution found hypertension as much 63,3%. High frequency distribution of triglyceride levels is 67,9%. The Chi Square analysis result there is a significant correlation of type 2 diabetes mellitus on triglyceride levels and blood pressure with Odds Ratio 6,865 with p-value of 0,009.

scholarly journals Cost-effectiveness study of antidiabetic drugs in type 2 diabetes mellitus patients from Mumbai, India

2017 ◽  
Vol 4 (9) ◽  
pp. 3180 ◽  
Author(s):  
Dnyanesh Limaye ◽  
Krishna Todi ◽  
Jay Shroff ◽  
Ashutosh Ramaswamy ◽  
Priyanka Kulkarni ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cost Effectiveness ◽  
Cross Sectional Study ◽  
Antidiabetic Drugs ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
The Cost

Background: Diabetes is fast gaining the status of a potential epidemic in India, with >62 million individuals currently diagnosed with the disease. India currently faces an uncertain future in relation to the potential burden that diabetes may impose on the country. An estimated US$ 2.2 billion would be needed to sufficiently treat all cases of type 2 diabetes mellitus (T2DM) in India. Many interventions can reduce the burden of this disease. However, health care resources are limited; thus, interventions for diabetes treatment should be prioritized. The present study assesses the cost-effectiveness of antidiabetic drugs in patients with T2DM from Mumbai, India.Methods: A prospective cross-sectional study was performed to assess the cost-effectiveness of antidiabetic drugs in patients with T2DM. Face-to-face interviews were conducted by using a validated questionnaire in a total of 152 (76 males, 76 females) patients with T2DM from F-North Ward, Mumbai, India. Cost-effectiveness was determined on the basis of cost of antidiabetic drug/s, efficacy, adverse drug reactions, safety of administration, frequency of administration, and bioavailability. Results: For treatment of T2DM in non-obese participants, Glimepiride+Pioglitazone costed least (`3.7) per unit of effectiveness followed by Glimepiride (`6.6), Gliclazide (`8.1), Repaglinide (`24.5), and Vildagliptin (`45.2). For treatment of T2DM in obese participants, Metformin cost least (` 6.7) per unit of effectiveness followed by Glimepiride + Metformin (`5.9) and Repaglinide (`24.5). Conclusions: In case of non-obese participants, cost effectiveness and prescribed treatments did not show a match, while for obese participants prescribed treatments were in line with cost effectiveness. 

scholarly journals STUDY OF HBA1C, LIPID PROFILE AND CYCLOPHILIN-A IN DIABETES MELLITUS

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
Rakesh Kumar Jha ◽  
Badade ZG ◽  
Sandeep Rai ◽  
Badade VZ
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Glycosylated Hemoglobin ◽  
General Medicine ◽  
Cyclophilin A ◽  
The Body ◽  
Glucose Levels

Introduction: Diabetes is a chronic disease that occurs when not enough insulin is produced by the pancreas or the body does not use the insulin produced. Because of increased blood glucose levels in the body, serious heart, kidneys, blood vessels, nerves and eyes damage are caused. Report says about 400 million people suffer from diabetes. Therefore present study is aimed to assess levels of HbA1c, Lipid profile and Cyclophilin A in diabetic patient. Material and Methods: The present study includes total 126 subjects comprising of 66 type 2 Diabetes Mellitus patients and 60 healthy individual. Blood samples are collected from the all subjects were processed for HbA1c, Lipid Profile and Cyclophilin A estimation, from OPD and General Medicine Wards. HbA1c is estimated by HPLC, lipid Profile by AU480 and the Cyclophilin A by ELISA method using commercially available Qayee-bio ELISA kit. Conclusion: Present study showed significantly increased levels of HbA1c, Lipid Profile and Cyclophilin A in T2DM patients. The elevated lipid profile may be due to the complication of Diabetic mellitus. CyA is increased as an inflammation marker. Keywords: T2DM: Type 2 diabetes mellitus, HbA1c: Glycosylated Hemoglobin, CyA: Cyclophilin-A

scholarly journals Correlation Analysis Study between Hearing Loss Occurence and Duration of Type 2 Diabetes Mellitus in Sultan Agung Islamic Hospital Semarang

Sains Medika ◽  
2015 ◽  
Vol 6 (1) ◽  
pp. 12
Author(s):  
Citta Arunika Risyudhanti ◽  
Agung Sulistyanto ◽  
Suparmi Suparmi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Hearing Impairment ◽  
Medical Records ◽  
Pure Tone ◽  
Pure Tone Audiometry ◽  
Chi Square ◽  
Cross Sectional

Introduction: Hearing impairment due to cochlear damage is one complication of Type 2 Diabetes Mellitus (DM2). Objective: This study aims to determine the relationship between duration of DM2 with hearing impairment.Method: The analytic observasional study with the cross sectional design using the medical record of DM2 outpatient in internal clinic of Islamic Sultan Agung Hospital Semarang and also pure tone audiometric examination’s record in Otorynolaryngology clinic of Islamic Sultan Agung Hospital Semarang.31 medical records of DM2 patients were meeting the inclusion and exclusion criteria. The data consist of 18 medical records of patients with less than6 years duration of DM2, and 13 medical records of patients with more than 6 years duration of DM2. The pure tone audiometry was used to classified the hearing impairment. The data analysis was conducted using SPSS 20.0. The correlation between the duration of DM2 and hearing impairment was analyzed using Chi Square test. The significance relation between the duration of DM type 2 and hearing impairment was analyzed using cooficient contigency, with significance of < 0.05. Result: hearing impairment’s distribution frequency on tested ears in Sultan agung Islamic Hospital Semarang were 27 ears having SNHL type (43,5%), 19 ears having CHL (30,6%) and 16 ears were normal (25,8%), p = 0,02 (p < 0,05). Conclusion: There is a weak correlation between the DM 2 duration and the incidence of hearing impairment in Sultan Agung Islamic Hospital Semarang.

scholarly journals The Relationship Of The Level Of Family Knowledge And Efforts To Prevent Complications Of Diabetes Mellitus Tipe 2 In The Working Area Of Babakan Public Health Center District Of Cirebon

2021 ◽  
Vol 8 (1) ◽  
pp. 14-19
Author(s):  
Lukatul Khoiriyah ◽  
Ramli Effendi ◽  
Thia Oktiany
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Health Center ◽  
P Value ◽  
Chi Square ◽  
Work Area ◽  
Chi Square Test ◽  
The Relationship

The level of family knowledge is a very important factor in the actions of families of people with Diabetes Mellitus, behavior based on knowledge will be easier to carry out than those not based on knowledge. Diabetes Mellitus is a disease that requires proper and immediate treatment efforts because it can cause complications such as heart disease, kidney failure, and damage to the nervous system. One way to overcome the effects of Type 2 Diabetes Mellitus is by applying a diet. This study aims to determine the relationship between the level of family knowledge with efforts to prevent complications of type 2 diabetes mellitus in the work area of Babakan Puskesmas, Cirebon Regency. This research method uses descriptive correlational, this research uses cross section research. The population is all families with type 2 Diabetes Mellitus in the work area of Babakan Puskesmas in Cirebon Regency as many as 144 respondents and sampling using Purposive Sampling obtained 60 respondents. The instruments used were questionnaire sheets, and data analysis using chi-square test that is the significance value α = 0.1. The results of the above study indicate between the level of family knowledge and prevention of complications of type 2 diabetes mellitus in getting p-value = 0.04, because the p-value of 0.04 <0.1 then Ho is rejected and Ha is accepted which means there is a relationship between the level of family knowledge and prevention of complications of type 2 diabetes mellitus in the work area of Babakan Health Center, Cirebon Regency.

scholarly journals Assessment of Carotid Atherosclerosis in Type 2 Diabetes Mellitus Patients with Microalbuminuria by High-Frequency Ultrasonography

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Yu-Hong Zhang ◽  
Yuan Gao ◽  
Xin Mao ◽  
Jing Shang ◽  
Ben-Li Su
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
High Frequency ◽  
Carotid Atherosclerosis ◽  
Univariate Analysis ◽  
Diabetic Patients ◽  
Multivariate Linear Regression Analysis ◽  
High Frequency Ultrasonography

The aim of this study is to evaluate carotid atherosclerosis in patients of type 2 diabetes mellitus with microalbuminuria (MA) by high-frequency ultrasonography. Two hundred and fifty patients of type 2 diabetes mellitus were divided into two groups according to urinary albumin excretion rate (UAER): normoalbuminuria group (130 cases) and microalbuminuria group (120 cases). The intimal-medial thickness (IMT) and the atherosclerotic plaques of carotid artery were observed in both groups by high-frequency ultrasound. Fasting blood glucose (FBG), hemoglobin A1c, and lipid profiles were measured. The values of IMT of microalbuminuria group were significantly higher than those of normoalbuminuria group (P<0.05). In univariate analysis, IMT was positively and significantly associated with age (r=0.265,P<0.05), waist circumference (r=0.263,P<0.05), body mass index (r=0.285,P<0.05), systolic blood pressure (r=0.276,P<0.05), UAER (r=0.359,P<0.05), HbA1c (r=0.462,P<0.05) and, duration of diabetes (r=0.370,P<0.05). In multivariate linear regression analysis, UAER and HbA1c were independent predictors of IMT (P<0.05for all). In the two groups, the rate of soft plaques was higher than that of dense plaques and calcified plaques. In conclusion, there is a significant association between microalbuminuria and IMT which is regarded as the early sign of carotid atherosclerosis in type 2 diabetic patients.

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