scholarly journals TYPE 2 DIABETES MELLITUS ON TRIGLYCERIDE LEVELS AND BLOOD PRESSURE

2019 ◽  
Vol 1 (1) ◽  
pp. 11-16
Author(s):  
Wirawan Anggorotomo ◽  
Tessa Sjahriani ◽  
Masroni Masroni
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Frequency Distribution ◽  
Metabolic Diseases ◽  
P Value ◽  
Chi Square ◽  
Chi Square Analysis

Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by an abnormality of insulin secretion, insulin work, or both. DM cases in Indonesia as many as 8,5 million cases in 2013. Prevalence based on diagnosis or symptoms according to the health departement of 2,1%.Purpose: To know the correlation of type 2 diabetes mellitus on triglyceride levels and blood pressureMethods: This study used secondary data derived from the medical record status of patients with diabetes mellitus. The method used is analytic observational with cross sectional approach. Sampling technique using purposive sampling. The population of this study is the diabetes mellitus type 2 in 2017 as many as 151. Sample of 109 respondents. Data analyzed by univariate and bivariate using Chi Square analysis.Results: The frequency of respondent characteristic on female gender as much 57,8%, based on age group >45 old counted 58,7%. Blood pressure frequency distribution found hypertension as much 63,3%. High frequency distribution of triglyceride levels is 67,9%. The Chi Square analysis result there is a significant correlation of type 2 diabetes mellitus on triglyceride levels and blood pressure with Odds Ratio 6,865 with p-value of 0,009.

scholarly journals The Relationship Of The Level Of Family Knowledge And Efforts To Prevent Complications Of Diabetes Mellitus Tipe 2 In The Working Area Of Babakan Public Health Center District Of Cirebon

2021 ◽  
Vol 8 (1) ◽  
pp. 14-19
Author(s):  
Lukatul Khoiriyah ◽  
Ramli Effendi ◽  
Thia Oktiany
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Health Center ◽  
P Value ◽  
Chi Square ◽  
Work Area ◽  
Chi Square Test ◽  
The Relationship

The level of family knowledge is a very important factor in the actions of families of people with Diabetes Mellitus, behavior based on knowledge will be easier to carry out than those not based on knowledge. Diabetes Mellitus is a disease that requires proper and immediate treatment efforts because it can cause complications such as heart disease, kidney failure, and damage to the nervous system. One way to overcome the effects of Type 2 Diabetes Mellitus is by applying a diet. This study aims to determine the relationship between the level of family knowledge with efforts to prevent complications of type 2 diabetes mellitus in the work area of Babakan Puskesmas, Cirebon Regency. This research method uses descriptive correlational, this research uses cross section research. The population is all families with type 2 Diabetes Mellitus in the work area of Babakan Puskesmas in Cirebon Regency as many as 144 respondents and sampling using Purposive Sampling obtained 60 respondents. The instruments used were questionnaire sheets, and data analysis using chi-square test that is the significance value α = 0.1. The results of the above study indicate between the level of family knowledge and prevention of complications of type 2 diabetes mellitus in getting p-value = 0.04, because the p-value of 0.04 <0.1 then Ho is rejected and Ha is accepted which means there is a relationship between the level of family knowledge and prevention of complications of type 2 diabetes mellitus in the work area of Babakan Health Center, Cirebon Regency.

scholarly journals HUBUNGAN POLA MAKAN TERHADAP STATUS GIZI PASIEN RAWAT JALAN DIABETES MELITUS TIPE 2 DI WILAYAH KERJA RUMAH SAKIT GRANDMED LUBUK PAKAM

2021 ◽  
Vol 3 (2) ◽  
pp. 168-171
Author(s):  
Raini Panjaitan ◽  
Reno Irwanto ◽  
Andreais Boffil Cholilullah ◽  
Salmi Angraini
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Nutrient Status ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Cross Sectional Design

Diabetes mellitus is a chronic disease characterized by hyperlycemia. Risk factors for type 2 diabetes mellitus due to intake of carbohydrates, fats and protein. This study aims to see the relationship between diet in the nutrient status of type 2 diabetes mellitus in out patient in Grandmed Hospital Lubuk Pakam. This research method is an observational description with cross-sectional design. The sample is patients type 2 diabetes mellitus in out patient in Grandmed Hospital Lubuk Pakam. The sample is 30 people. The instruments are Food Recall 24 Hours and analyzed by nutrition app Nutri Survey. The data analysis used in this study was the Chi-Square test (95% CI) From the result of this research showed that 44,6% of patients with excess carbohydrate intake with a p value of 0.000 ≤ α (0,05). this research showed that 49,0% of patients with excess fat intake with a p value of 0.000 ≤ α (0,05). this research showed that 38,0% of patients with excess protein intake with a p value of 0.000 ≤ α (0,05). The conclusion are that there is significant relationship between diet in the nutrient status of type 2 diabetes mellitus in out patient in Grandmed Hospital Lubuk Pakam and type 2 diabetes mellitus in out patient nutrient status characteristics categorized as obesity.  

scholarly journals Effects of yoga in modifying blood pressure in patients of type 2 diabetes mellitus

2018 ◽  
Vol 6 (9) ◽  
pp. 3080
Author(s):  
Namita Shrivastava ◽  
Basant Kumar Maheswari ◽  
Debapriya Rath ◽  
Debashree Sarkar
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Diastolic Blood Pressure ◽  
Dietary Habits ◽  
P Value

Background: The incidence of diabetes mellitus is increasing with the increase in unhealthy dietary habits, physical inactivity and sedentary lifestyle. Hypertension complicated with diabetes further aggravates the problem. Yoga has been found to be helpful in delaying the progression and complications of the disease. The present study was undertaken with an aim to evaluate the effect of yoga in modifying blood pressure in patients of diabetes mellitus.Methods: Thirty patients of diabetes mellitus who were known case of hypertension were taken and their fasting and post-prandial blood glucose levels, systolic and diastolic blood pressure and waist circumference were analysed before and after ninety days of yoga in the department of physiology and biochemistry.Results: Systolic and diastolic blood pressure, waist circumference and fasting and post-prandial blood glucose level showed significant reduction (p value <0.05).Conclusions: This study emphasizes the importance of yoga in the control and management of type 2 diabetes mellitus and hypertension.

scholarly journals The influence of baseline diastolic blood pressure on the effects of intensive blood pressure lowering on cardiovascular outcomes and all-cause mortality in type 2 diabetes mellitus

2020 ◽  
Author(s):  
Olesya L. Ilkun ◽  
Tom Greene ◽  
Alfred K. Cheung ◽  
Paul K. Whelton ◽  
Guo Wei ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Diastolic Blood Pressure ◽  
Controlled Trial ◽  
Cardiovascular Outcomes ◽  
P Value

<b><i>Objective:</i></b> To examine whether low baseline diastolic blood pressure (DBP) modifies the effects of intensive systolic blood pressure (SBP) lowering on cardiovascular outcomes in type 2 diabetes mellitus (T2DM). <p><b><i>Research Design and Methods:</i></b> The Action to Control Cardiovascular Risk in Diabetes Blood Pressure trial (ACCORD BP),a 2X2 factorial randomized controlled trial, examined effects of SBP (<120 vs. <140 mmHg) and glycemic (HbA1C < 6% vs. 7.0–7.9% (<42 vs 53-63 mmol/mol)) control on cardiovascular events in T2DM (N=4731). We examined whether effects of SBP control on cardiovascular composite was modified by baseline DBP and glycemic control. </p> <p><b><i>Results: </i></b>Intensive SBP lowering decreased the risk of the cardiovascular composite (HR 0.76, 95% CI 0.59 to 0.98) in the standard glycemic arm but not in the intensive glycemic arm (HR=1.06, 95% CI 0.81 to 1.40). Spline regression models relating the effects of the intervention on the cardiovascular composite across the range of baseline DBP did not show evidence of effect modification by low baseline DBP for the cardiovascular composite in the standard or intensive glycemic arms. The relation between the effect of the intensive SBP intervention and baseline DBP was similar between glycemic arms for the cardiovascular composite (3-way interaction p-value = 0.83).</p> <p><b><i>Conclusions: </i></b>in persons with T2DM, intensive SBP lowering decreased the risk of cardiovascular composite endpoint irrespective of baseline DBP in the setting of standard glycemic control. Hence, low baseline DBP should not be an impediment to intensive SBP lowering in T2DM patients treated with guidelines recommended standard glycemic control. </p>

Effect the Pharmaceutical Care and Health Education on Knowledge and Disease Control for Type 2 Diabetes Mellitus Patients: A sample of Iraqi Patients

2020 ◽  
pp. 40-54
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Health Education ◽  
Pharmaceutical Care ◽  
P Value ◽  
Diabetes Knowledge

Objective: To study the effect of Pharmaceutical Care (PC) program and health education delivered by pharmacist on Type 2 Diabetes Mellitus (T2DM) patient’s knowledge about diabetes, glycemic control, blood pressure and Body Mass Index (BMI). Patients and methods: A prospective interventional study including T2DM patients with poor glycemic control, i.e. glycated hemoglobin (HbA1c) more than 7%. Patients receiving PC and education about T2DM and cardiovascular disease by the researcher pharmacist. Patients were followed for 26 weeks. The study parameters included HbA1c, Fasting Blood Sugar (FBS), Systolic Blood pressure (SBP), Diastolic Blood Pressure (DBP), BMI and Diabetes Knowledge Questionnaire (DKQ-24). Results: Thirty-eight T2DM patients were included in the study. Thirty-two completed the program. A significant decrease in the HbA1c and FBS at the end line measurements (from 9.1% to 7.4%, P-value = 0.001) and (from 187.4 to 135.3, P-value = 0.001) respectively. A significant decrease occurred in both SBP and DBP (from 129.8 to 125.2, P-value = 0.009) and (from 82.0 to 77.9, P-value =0.001) respectively. Diabetes knowledge score also showed a significant increase at the end of study (from 52.6 to 63.7, P-value =0.001) Conclusion: Pharmaceutical care and health education with continuous follow up delivered by the pharmacist even for a relatively short period of time in collaboration with specialist physician, resulted in improved T2DM Knowledge plus better glycemic and blood pressure control.

scholarly journals Clinical And Biochemical Outcomes Of Sodium-Glucose Co-Transporter-2 (SGLT2) Inhibitors In Type 2 Diabetes Mellitus Patients

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. A467-A467
Author(s):  
Muhammad Saleem ◽  
Nanik Ram ◽  
Sajjad Ali Khan ◽  
Zafar Aleem Suchal ◽  
Muhammad Mustansir Mehdi Khan
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Standard Deviation ◽  
P Value ◽  
Oral Glucose ◽  
Glucose Lowering

Abstract Background: SGLT-2 inhibitors are a group of oral medications that work independently of insulin working as anti-diabetics by enhancing the excretion of glucose. The purpose of our study was to assess the improvement in terms of HbA1c, weight, blood pressure and BMI and the hepatics and renal effect in terms of SGPT and Creatinine in patients already on three oral glucose lowering agents when SGLT-2 inhibitor was added to their medications. Methods: This retrospective, real world, single center study included 99 patients (mean age [Standard Deviation]: 53.8 [9.63] years) with poorly control type 2 diabetes. Data was recorded at three times, before the addition of SGLT-2 inhibitor and then at 3 and 6 month follow up after the drug had been added in patient’s medications. Physical parameters namely weight, BMI and blood pressure were recorded in the clinic while HbA1c, SGPT and Creatinine were checked by laboratory. Results: Improvement was seen in all parameters at both 3 and 6 month follow up interval. The reduction in HbA1c was statistically significant (P-value &lt; 0.001) with (Mean Reduction [Standard Deviation)) 0.81[1.02] % at 3 months and 1.07[1.11] % at 6 months. Weight was also significantly reduced (P-value &lt; 0.001) with (MR [SD]) 1.83[2.32] kg at 3 and 4.02[6.04] kg at 6 months. Statistically significant reduction (P-value &lt; 0.001) in BMI was also seen with 0.69[0.95] kgm-2 at 3 months and 2.13[3.41] kgm-2 at 6 months of follow up. The systolic blood pressure showed significant reduction (P-value &lt; 0.05) of 5.9[15.76] mmHg at 3 months and 6.37[18.33] mmHg at 6 months. The creatinine and SGPT values of the patient showed minimal variation over the course of these 6 months of follow up. Conclusion: Our study showed that SGPT-2 can be reliably used in patients in which diabetes is not being controlled by other glucose lowering agents and is safe for use in patients in which hepatic and renal function needs to be preserved. Keywords: SGLT-2 inhibitors, Type 2 Diabetes Mellitus, Pakistan

scholarly journals Prevalence of Microalbuminuria and Associated Factors Among Type 2 Diabetes Mellitus Patients in Jigjiga Town Public Hospitals, Somali Regional State, Ethiopia, 2020

2021 ◽  
Author(s):  
Abdilahi Ibrahim Muse ◽  
Mohamed Omar Osman ◽  
Girma Tadesse Wedajo ◽  
Kalkidan Hassen Abate ◽  
Ahmed Mohammed Ibrahim ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Associated Factors ◽  
Density Lipoprotein ◽  
Public Hospitals ◽  
P Value ◽  
Adult Type

Abstract Background and AimUnder normal circumstances, a urine albumin excretion of 5-10 mg/L is considered to be normal. Micro-albuminuria is, however, defined as a level of albumin in the urine that is between 20 mcg/min, and 200 mcg/min (30-300mg/24h) with normal urine flow of 1 ml/min.The aim of this study is to assess the prevalence of micro-albuminuria and associated factors among adult type two diabetes mellitus clients in public hospitals of Jigjiga town, Somali region, Ethiopia, from April 1 to July15, 2020Methods: Institutional based cross-sectional study design was used from April 1 to July 15, 2020. A pre-tested structured questionnaire was used to collect a data from 204 Type 2 diabetes mellitus patients visiting at Karamara general and Jigjiga University referral hospitals for follow up. Descriptive statistics was computed. Logistic regression model was used to identify covariates using SPSS version 20. The direction and strength of statistical association was measured by odds ratio with 95 % CI and a P-value < 0.05 was considered as statistically significant.Results: The prevalence of micro-albuminuria was 48.0% with [95% CI (41.2, 54.9)] Duration of DM between 11-20 years [AOR=3.71; 95% CI (1.45, 9.49)] Family history of hypertension [AOR=2.24; 95% CI: (1.02, 4.70)] Systolic blood pressure [AOR=3.36; 95% CI:(1.39, 8.13)], Low density lipoprotein [AOR=5.60; 95%CI: (2.22,14.11)] High density lipoprotein [AOR=5.210;95%CI:(2.067,13.131)] and Glycated hemoglobin [AOR = 3.246; 95% CI (1.356, 7.78)] were significantly associated with micro-albuminuriaConclusion: There is a significant level of micro-albuminuria among type 2 diabetes mellitus patients. Effective secondary prevention program directed on blood glucose and lipid with steps to improve blood pressure are critical in undertaking in the setting and regular screening of micro-albuminuria is needed so that an early preventive and treatment measures against its burden are put in place.

scholarly journals Association analysis of SOCS3, JAK2 and STAT3 gene polymorphisms and genetic susceptibility to type 2 diabetes mellitus in Chinese population

2022 ◽  
Vol 14 (1) ◽  
Author(s):  
Yang Zhang ◽  
Chunwen Lin ◽  
Rong Chen ◽  
Ling Luo ◽  
Jialu Huang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Environmental Factors ◽  
Genetic Susceptibility ◽  
Frequency Distribution ◽  
Chinese Population ◽  
Chi Square ◽  
Chi Square Test

Abstract Aim The association of polymorphisms in the three genes of SOCS3, JAK2 and STAT3 with genetic susceptibility to type 2 diabetes mellitus (T2DM) was explored, and its interaction with environmental factors such as hypertension and triglycerides was analyzed. Methods The Hardy–Weinberg balance test was used to analyze the random balance of genes in the population. The analysis of the association of SNPs with T2DM was performed using Pearson’s chi-square test. Haplotype frequency distribution, SNPs-SNPs interaction and environmental factors were analyzed by chi-square test and logistic regression. Results The genotype distribution of SNPs rs2280148 of the SOCS3 gene was statistically significant. The allele frequency distribution of SNPs (rs4969168/rs2280148) was statistically different. After covariate correction, the SOCS3 gene locus (rs4969168) showed an association with T2DM in additive model, while the rs2280148 locus showed an association with T2DM in all three models. The locus (rs10974914/rs10815157) allele and genotype frequency distribution of JAK2 were statistically significant. After covariate correction, two SNPs in the gene showed association with T2DM in both additive and recessive models. The distribution of genotype frequencies of SNPs rs1053005 locus in gene STAT3 was statistically significant between the two groups. In recessive genetic models, rs1053005 locus polymorphisms was associated with T2DM. Haplotype S3 (G G)/S 4 (G T) of the SOCS3 gene as well as haplotype J2 (A G)/J 3 (G C) of the JAK2 gene were closely associated with T2DM. There was an interaction between SNPs rs4969168 and SNPs rs2280148 in the SOCS3 gene. There was an interaction between the SOCS3, JAK2 and STAT3 genes and hypertension/triglycerides. Conclusion The SOCS3 and JAK2 genes may be associated with T2DM in the Chinese population, in which SNPs carrying the A allele (rs4969168)/G allele (rs2280148)/C allele (rs10815157) have a reduced risk of T2DM. Haplotype S3 (G G)/S 4 (G T) of the SOCS3 gene and haplotype J2 (A G)/J 3 (G C) of the JAK2 gene may be influencing factor for T2DM. The interaction between SNPs rs4969168 and SNPs rs2280148 increases the risk of T2DM. Hypertension and triglycerides may interact with SNPs of T2DM susceptibility genes.

scholarly journals Faktor-faktor yang berhubungan dengan kecemasan dan depresi pada pasien diabetes melitus tipe 2

2020 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Pipin Nurhayati
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Family Support ◽  
Functional Ability ◽  
P Value ◽  
Chi Square ◽  
Long Period ◽  
Type 2 Dm

Physical, psychological, and social changes are the changes that occur due to the various complications that accompany the disease DM type 2. Psychological changes that occur, such as stress, and depression. The purpose of this study is to determine the factors related to anxiety and depression in patients with type 2 diabetes mellitus. This type of research was descriptive with cross sectional design. Sampling technique used total sampling with 60 people. The instrument used DASS 42 and BDI questioner. Data were analyzed by chi square. Chi square test results obtained factors related to anxiety in patients with type 2 diabetes mellitus are age (p value = 0,000), long suffering from type 2 DM (p value = 0,000), education (p value = 0,040), comorbidities (p value = 0,000) and family support (p value = 0,000). While factors which were not related to anxiety in patients with type 2 diabetes mellitus were impaired functional ability (p value = 0,517). Factors that related to depression in patients with type 2 DM were age (p value=0.007), education (p value = 0,001), comorbidities (p value = 0,000) and family support (p value = 0,040). While factors unrelated to anxiety of patients with type 2 DM are long period of type 2 DM (p value = 0,797) and functional ability disorder (p value = 0,435). Conclusion of the factors related to anxiety of patient with type 2 DM are age, long period of type 2 DM, education, comorbidities and family support, while factors that unrelated to anxiety of patients with type 2 DM are functional ability disorder, factors that related to depression of patients with type 2 DM are age, education, comorbidities, and family support, while factors that unrelated to depression of patients with type 2 DM are long period of type 2 DM and functional ability disorder.

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