ASSOCIATED DISEASES IN ROTAVIRUS GASTROENTERITIS IN CHILDREN HOSPITALIZED IN CLINICAL INFECTIOUS DISEASES HOSPITAL OF CONSTANTA

2017 ◽  
Vol 20 (3) ◽  
pp. 130-134
Author(s):  
Simona Diaconu ◽  
◽  
Simona Claudia Cambrea ◽  
Lucian Cristian Petcu ◽  
Sorin Rugina ◽  
...  

Our study included 505 children hospitalized in the Clinical Hospital of Infectious Diseases Constanta in 2011-2012 with gastroenteritis with rotavirus. We analyzed the medical records of the patients and extracted demographic data, temperature, and frequency of vomiting and diarrheic stools. We divided the group of cases into 4 groups associated with: respiratory disease (RD) – 160 cases, digestive disease (DD) – 52 cases, eruptive disease (ED) – 11 cases, and a group without other associated diseases (simple) – 282 cases. We found significant differences between the four groups regarding the number of stools, the number of vomiting per day, the mean value of maximum temperature, the mean value of hospitalization.

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1119.1-1119
Author(s):  
L. Nacef ◽  
Y. Besbes ◽  
Y. Mabrouk ◽  
H. Ferjani ◽  
K. Maatallah ◽  
...  

Background:The lipid paradox is termed the decreased cholesterol level in rheumatoid arthritis (RA). Nevertheless, the apolipoprotein levels are usually higher than a healthy person and are predictors of cardiovascular events.Objectives:We aimed to describe lipid abnormalities in RA patients and to look for predictor factors of these changes.Methods:The prospective study was carried out on patients with RA who met the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria. These patients were followed in the rheumatology department of the Kassab Institute.We collected the socio-demographic data, biological and immunological parameters.The lipid assessment included: a measurement of total cholesterol (TC), HDL, LDL, and triglycerides (TG). Lipoproteins APOA1 and APOB were measured. All data were collected after patient consent.Results:Of the 47 patients recruited, 78.7% were female. The mean age was 52.5 ±11.06 [32-76]. The average RA progressed from 86.25 ±63 months [5-288] and was erosive in 81.6% of cases. The rheumatoid factor (RF) was positive in 57.8% of patients, and citrullinated antipeptide antibodies (ACPA) were present in 62.2%. Eight patients had a previous CV history.Mean TC was 4.42 ±1.3 [1.2-7.58], mean HDL was 1.38 ±0.73 [0.18-4.10], mean LDL was 2.55 ±1.16 [0.24-5.54]. The mean TG value was 1.28 ±0.6 [0.24-5.54]. TC elevation was found in 9.1% of cases, HDL in 21.3% of cases, LDL in 5.5% of cases, and TG in 16.4% of cases. Mean APOB/APOA1 ratio was 0.67 ±0.18 [0,46-1,11]. LDL elevation was associated to a high DAS28 (p=0.06, r=0.512). APOA1 was associated to a low DAS28 (p=0.04, r=-0.642).The mean value of APO A1 was 1.36 ±0.21 [0.84-1.81], that of APOB was 0.90 ±0.22 [0.58-1.40]. APOA1 values were lower in patients with high-level LDL (p=0.767). The APOB value was associated with lipid disturbance without significant correlation (p=0.291).Conclusion:Lipid test abnormalities can be found in RA patients outside of any known CV risk factors. APOA1 seems to have a protective effect. Screening and treatment of these abnormalities can prevent CV risk.References:[1]Miguel Bernardes and al. Coronary artery calcium score in female rheumatoid arthritis patients: Associations with apolipoproteins and disease biomarkers. Int J Rheum Dis. 2019;00:1–16.[2]Anna So dergren and al. Biomarkers associated with cardiovascular disease in patients with early rheumatoid arthritis. PLOS ONE. August 5, 2019.Disclosure of Interests:None declared


2008 ◽  
Vol 23 (6) ◽  
pp. 510-515 ◽  
Author(s):  
Hassan Ali Mohebbi ◽  
Shaban Mehrvarz ◽  
Masoud Saghafinia ◽  
Yadollah Rezaei ◽  
Seyed Mohsen Towliat Kashani ◽  
...  

AbstractBackground:In December 2003, the residents of Bam, Iran experienced an earthquake that measured 6.6 on the Richter scale and destroyed >90% of the city. After the assessment and initial treatment of injuries at national and international field hospitals, a considerable number of victims (approximately 12,000) were transferred to tertiary referral hospitals around the country. Objective: This report evaluated the injuries of 854 victims transferred to 12 referral hospitals in Tehran.Methods:The demographic data, injury patterns, injury severity score (ISS), diagnosis, treatment, and outcome data of 854 Bam earthquake victims were assessed.Results:There were 467 (54.7%) males and 387 (45.3%) females. The mean age of the patients was 29.0 years. Transportation by aircraft was the most common method used for evacuation, which was used to evacuate 555 patients (65%). Fifty-four percent of the victims required initial medical aid at field hospitals before transportation to Tehran. There were 1,322 patients with injuries, of which, fractures of the lower extremities were the most common (331; 25%). Limb fixation was the most commonly performed primary procedure in emergency wards (389 cases, 39.9%). The mean value ±SD for ISS was 6.7 ±5.2. Orthopedic operations were the most frequent surgical procedures performed (195/260 operations, 75%) and the overall mortality rate was 1.6% (n = 14).Conclusions:Along with the crucial importance of aid provided by national and international field hospitals in disasters, suitable triage of casualties and preparedness of tertiary referral centers in unaffected regions also play an important role in providing medical care to disaster victims. During these situations, the number of victims cannot be predicted accurately, and sufficient medical care, particularly for orthopedic problems, can be provided by referral centers.


2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Yong Koo Kang ◽  
Myung Jun Kim ◽  
Hong Kyun Kim ◽  
Bo Young Chun

Purpose. To study the correlation between ocular parameters and subjective pain that patients perceived during phacoemulsification.Methods. Medical records of 142 patients who underwent standard phacoemulsification under topical anesthesia between March and August 2016 were retrospectively reviewed. The pain during phacoemulsification and 1 h after surgery was assessed and compared using a visual analog scale. In addition, demographic data, preoperative biometric parameters, and intraoperative surgical parameters were recorded.Results. Mean age of patients was 67.49 ± 12.50 years. The mean pain score was 2.26 ± 0.85 during phacoemulsification and 0.40 ± 0.69 postoperatively. Intraoperative pain was significantly associated with higher preoperative intraocular pressure (β = 0.220,P=0.016), greater anterior chamber depth (β = 0.210,P=0.028), and greater axial length (β = 0.181,P=0.043).Conclusions. To reduce the subjective pain when patients have high preoperative intraocular pressure, large anterior chamber depth, or great axial length, supplementary procedures may be required.


e-CliniC ◽  
2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Herry Y. Tia ◽  
Lucky T. Kumaat ◽  
Diana Ch. Lalenoh

Abstract: The occurence of increased or decreased levels of hemoglobin of post-caesarean patients depends on the intake of nutrients during pregnancy, bleeding, and anemia. In case of massive and life-threatening bleeding during the caesarean section, blood transfusion has to be administered to revive the patient in critical condition. This study was aimed to obtain the patients’ levels of hemoglobin in either pre- and post-operative caesarean section without blood transfusion. This was a retrospective descriptive study using data of medical records at the Installation of Medical Record Department of Prof. Dr. R. D. Kandou Hospital Manado from September 2015 to August 2016. There were 32 patients in this study. The result showed that the mean values of pre-operative Hb was 12.4 g/dL and of post-operative Hb was 11.5 g/dL with a difference of 0.9 g/dL. Decreased levels of hemoglobin occured in 28 patients. It is discerned that the mean value of pre-operative Hb was 12.4 g/dL while of post-operative Hb was 11.3 g/dL with a difference of 1.1 g/dL. Furthermore, increased levels of hemoglobin occured in 4 patients, showing that the mean value of pre-operative Hb was 12.1 g/dLwhereas of post-operative Hb was 12.5 g/dL with a difference of 0.4 g/dL. Based on the characteristics of pregnant women, 23 cases (71.9%), were in the age group of 20-35 years; 18 cases (56.3%) of hemorrhage of 500-1000 ml; and 25 cases (78.1%) of 6-10 days length of hospitalization. Conclusion: In this study, there was increased as well as decreased hemoglobin levels in caesarean patients who were not administered blood transfusion during surgery.Keywords: hemoglobin, caesarean section, blood transfusion Abstrak: Terjadinya peningkatan maupun penurunan kadar hemoglobin pada operasi seksio sesarea tergantung pada asupan zat-zat nutrisi saat kehamilan, perdarahan, dan anemia. Jika terjadi perdarahan hebat selama operasi seksio sesarea berlangsung yang mengakibatkan penurunan kadar hemoglobin mendekati batasan untuk dilakukan transfusi darah, maka transfusi darah diberikan untuk menolong pasien pada kondisi kritis. Penelitian ini bertujuan untuk mengetahui gambaran kadar hemoglobin pasien pra dan pasca operasi seksio sesarea yang tidak mendapat transfusi darah. Jenis penelitian ialah deskriptif retrospektif menggunakan data rekam medik pasien seksio sesarea di Instalasi Rekam Medik RSUP Prof. Dr. R. D. Kandou Manado periode September 2015 sampai Agustus 2016. Hasil penelitian memperlihatkan 32 pasien yang memenuhi kriteria inklusi. Nilai mean kadar Hb pra 12,4 g/dL dan kadar Hb pasca 11,5 g/dL dengan selisih 0,9 g/dL. Penurunan kadar hemoglobin terdapat pada 28 pasien dengan nilai mean kadar Hb pra 12,4 g/dL dan kadar Hb pasca 11,3 g/dL (selisih 1,1 g/dL). Peningkatan kadar hemoglobin terdapat pada 4 pasien dengan nilai mean kadar Hb pra 12,1 g/dL dan kadar Hb pasca 12,5 g/dL (selisih 0,4 g/dL). Karakteristik ibu hamil didapatkan terbanyak kelompok usia 20-35 tahun berjumlah 23 kasus (71,9%), perdarahan 500-1000 cc berjumlah 18 kasus (56,3%), dan lama rawat inap 6-10 hari berjumlah 25 kasus (78,1%). Simpulan: Pada pasien operasi seksio sesarea yang tidak mendapat transfusi darah dapat terjadi penurunan maupun peningkatan kadar hemoglobin. Kata kunci: hemoglobin, seksio sesarea, transfusi darah


2019 ◽  
Author(s):  
Andrea Torneri ◽  
Amin Azmon ◽  
Christel Faes ◽  
Eben Kenah ◽  
Gianpaolo Scalia Tomba ◽  
...  

AbstractOne of the key characteristics of the transmission dynamics of infectious diseases is the generation time which refers to the time interval between the infection of a secondary case and the infection of its infector. The generation time distribution together with the reproduction number determines the rate at which an infection spreads in a population. When defining the generation time distribution at a calendar time t two definitions are plausible according whether we regard t as the infection time of the infector or the infection time of the infectee. The resulting measurements are respectively called forward generation time and backward generation time. It has been observed that the mean forward generation time contracts around the peak of an epidemic. This contraction effect has previously been attributed to either competition among potential infectors or depletion of susceptibles in the population. The first explanation requires many infectives for contraction to occur whereas the latter explanation suggests that contraction occurs even when there are few infectives. With a simulation study we show that both competition and depletion cause the mean forward generation time to contract. Our results also reveal that the distribution of the infectious period and the reproduction number have a strong effect on the size and timing of the contraction, as well as on the mean value of the generation time in both forward and backward scheme.Author summaryInfectious diseases remain one of the greatest threats to human health and commerce, and the analysis of epidemic data is one of the most important applications of statistics in public health. Thus, having reliable estimates of fundamental infectious diseases parameters is critical for public health decision-makers in order to take appropriate actions for the global prevention and management of outbreaks and other health emergencies. A key example is given by the prediction models of the reproduction numbers: these rely on the generation time distribution that is usually estimated from contact tracing data collected at a precise calendar time. The forward scheme is used in such a prediction model and the knowledge of its evolution over time is crucial to correctly estimate the parameters of interest. It is therefore important to characterize the causes that lead to the contraction of the mean forward generation time during the course of an outbreak.In this paper, we firstly identify the impact of the epidemiological quantities as reproduction number, infectious period and population size on the mean forward and backward generation time. Moreover, we analyze the phenomena of competition among infectives and depletion of susceptible individuals highlighting their effects on the contraction of the mean forward generation time. The upshot of this investigation is that the variance of the infectious period distribution and the reproduction number have a strong impact on the generation times affecting both the mean value and the evolution over time. Furthermore, competition and depletion can both cause contraction even for small values of the reproduction number suggesting that, in epidemic models where the generation time is considered time-inhomogeneous, estimators accounting for both depletion and competing risks are to be preferred in the inference of the generation interval distributions.


Author(s):  
Georges Ziade ◽  
Dayane Daou ◽  
Desiree Karam

AbstractThis study aimed to evaluate satisfaction in terms of facial appearance, quality of life, and adverse effects in patients undergoing the facial thread lifting procedure using the absorbable facial threads anchored on the superficial and deep temporal fascias. The charts of patients for whom facial anchored thread lifting was performed using absorbable threads between February 2017 and September 2019 were reviewed. Demographic data including age and gender as well as data from the Face-Q scales were collected. Descriptive analysis was made for the adverse effects 1 week after the procedure. The mean value of adverse effects scales was compared 1 and 2 weeks after the procedure and also the mean values of facial appearance and quality-of-life scales were compared at baseline, 6 months, and 12 months after the procedure. All recruited subjects were females with a mean age of 43.42 years. There was a statistically significant decrease in the rate of adverse effects following the procedure between the first and second week. The mean difference in patients' perceived age 6 and 12 months after the procedure was statistically significant when compared with baseline. The psychological distress significantly decreased and the psychological function improved 6 and 12 months after the procedure. The overall satisfaction with facial appearance increased significantly after 6 months with a mean of 20.08. This was maintained at 12 months. The satisfaction in skin appearance, cheeks, nasolabial folds, marionettes, lower face, and jawline appearances improved significantly 6 months after the procedure. This was also maintained at 12 months. Face lifting using the polycaprolactone threads anchored on the temporalis fascia showed a significant improvement in the quality of life and facial appearance. The adverse effects are tolerable starting 2 weeks after the procedure.


Author(s):  
Juan Zhou ◽  
Yingzheng Tan ◽  
Llingli Hu ◽  
Dan Li ◽  
Xiaojin He ◽  
...  

Abstract In view of the influence of ABO blood group antigens on infectious diseases, we explore the effect of ABO blood types on SARS-COV-2 infection. In this report, demographic data of 80 COVID-19 patients and 26 SARS-COV-2 asymptomatic carriers were collected based on electronic medical records. The results indicated that the distribution of ABO blood group in the confirmed patients was significantly different from asymptomatic carriers; importantly, antigen A carrier have significantly higher risk of developing into severe or critically cases than other types. These data present further evidence for the association of the blood groups to susceptibility to SARS-COV-2 infection.


2019 ◽  
Vol 6 (6) ◽  
pp. 2504
Author(s):  
Poornima Shankar ◽  
Nithya E. ◽  
Kavya C.

Background: Dengue is a mosquito borne disease of significant morbidity and mortality. Dengue viral infection has been shown to be associated with electrolyte abnormalities and renal dysfunction. It is necessary to have a thorough understanding about electrolyte disturbances in Dengue, so as to predict, diagnose and treat them accordingly. The aim and objective of this study is to study electrolyte disturbances in dengue fever and its correlation with severity of dengue fever.Methods: This study was performed in a tertiary care centre in Bangalore , India. The study was a prosspective observational study. 200 Patients diagnosed with Dengue were enrolled for the study. Patients demographic data, clinical history, electrolyte values were recorded and analysed.Results: In our study majority of patients belonged to 5-12 years age group ie 47%. Fever was found to be the most common presentation in 196 patients (98%) followed by myalgia in 142 patients (71%), headache in 102 patients (51%), skin rash in 43 patients (21.5%). The mean value of serum sodium observed was 133.69 mEq/L and of serum potassium was 3.58 mEq/L and there was positive and significant correlation between difference in serum sodium and potassium levels with severity of dengue fever.Conclusions: Dyselectrolytemia is more common in dengue fever. Serum electrolytes testing early is very important in dengue patients during management so that if abnormalities are found, they can be appropriately managed as some of these abnormalities may lead to increased severity as well as mortality.


2020 ◽  
Vol 4 (1) ◽  
pp. 87-94
Author(s):  
Frita Dwi Luhuria ◽  
Defrin Defrin ◽  
Andi Friadi

The Risk Malignancy Index (RMI) is one of the simplest assessments that can assist in diagnosing and determining the prognosis of benign and malignant adnexa masses. Epithelial carcinoma is the most common type of about 90% of ovarian cancers.  As many as 35-40% of the epithelial type are serous and 6-10% are musinosum.This study aims to compare the picture of RMI value on the incidence of ovarian cancer serosum and musinosum type. This study was cross sectinal comparative study from medical records of ovarian cancer patients at obstetrics and gynecology section in DR M Djamil Hospital Padang from January 1st, 2017 until December 31st, 2017. The population was found one hundred and forty of patients with ovarian cancer and only one hundred and twenty nine of patients met the inclusion criteria and there were no exclusion criteria. Next RMI value is calculated based on RMI 1 formula, result is described in tabular form and data processing with SPSS program. Conclucion of this study is there were no differences in age distribution, ascites occurrence and age of menopause in serous and musinosum ovarian cancer. There is a difference in Ca, 125 levels in serous with musinosum ovarian cancer which also contribute to the high value of RMI. The mean value of patients‘s RMI in serous type ovarian cancer is higher than the mean value of RMI in patients with type Musinosum ovarian cancer. Keywords: index of risk malignancy, menopause, ultrasonography, anatomic pathology, serous ovarian carcinoma


2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Razieh Sangsari ◽  
Maryam Saeedi ◽  
Maliheh Kadivar ◽  
Sara Khalighi

Background: The prevalence of asthma is higher in icteric babies. It is thought that eosinophilia and asthma are complications of phototherapy rather than hyperbilirubinemia. Objectives: Since there is little data in this regard, we evaluated the relationship between phototherapy and the level of eosinophils in this study. Methods: In this cross-sectional prospective study, we assessed icteric neonates admitted to the neonatal and intensive care unit of Children’s Medical Center of Tehran during 2017 - 2018. Laboratory data including serum bilirubin and count of blood cell differentiation for eosinophils, before, during, and after phototherapy besides demographic data like age, gender, gestational age, and duration of phototherapy were collected. Results: Totally, 163 neonates (52.1% male and 47.9% female) with a mean age of 5.49 ± 4.01 days, enrolled in the study. The prevalence of term neonates was 81% and 19% were preterm. The mean of serum total bilirubin was 17.91 ± 3.37 mg/dL. Compared to the mean value of eosinophils before phototherapy, this value in the first (P = 0.001) and second (P < 0.001) days were significantly higher. In female neonates, there was a significant increase in eosinophils in the first (P = 0.001) and second (P < 0.001) day of the post-treatment period. However, in male subjects, this increase was significant only in the second day after phototherapy (P = 0.001). In neonates less than one week of age, this count was significantly increased on the first (P = 0.003) and second (P < 0.001) day after phototherapy. In cases with hemolytic hyperbilirubinemia, eosinophils count before phototherapy and the second day was significant (P = 0.006). The mean of eosinophils in first and second days after phototherapy was not correlated with the severity of hyperbilirubinemia but there is a significant negative correlation between the mean total bilirubin of patients with mean eosinophils before phototherapy. Conclusions: Our findings showed that there was a significant relationship between hyperbilirubinemia and its therapeutic phototherapy with an increasing level of peripheral eosinophils count in neonates.


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