scholarly journals The use of vyazolistnogo labaznik (Filipendula ulmaria (L.) Maxim) to increase the antioxidant activity of hepatoprotective collection of plant origin

2020 ◽  
Vol 61 (3) ◽  
pp. 112-119
Author(s):  
Anatoly A. Lapin ◽  
◽  
Valery N. Zelenkov ◽  
Keyword(s):  
Antioxidant Activity ◽  
Linear Equation ◽  
Linear Dependence ◽  
Water Extract ◽  
Plant Origin ◽  
Water Extracts ◽  
Filipendula Ulmaria ◽  
Total Antioxidant ◽  
High Antioxidant Activity ◽  
Confidence Value

Currently available on the pharmaceutical market drugs do not fully have high antioxidant activity, so the search for new means to prevent and eliminate liver damage is relevant. The purpose of this study was to evaluate the use of vyazolistnogo labaznik to increase the antioxidant activity of hepatoprotective collections of plant origin. Water extracts of hepatoprotective collection (GPS) have significant antioxidant activity, which is reflected by its linear dependence on the amount of GPS taken for extraction with a confidence value of approximation R2 of 0.989. Total antioxidant activity (TAA) the collection infusion increased from 0.690 to 4.883 g of rutin (Ru) per 1 dm3 when brewing from 5 g to 40 g of collection per 1 liter of boiling water, while the linear dependence twice reaches the plateau when the amount of collection taken for extraction is 10-12 g and 18-21 g, the TAA of GPS infusions was 1.35±0.004 and 2.26±0.11 g of Ru per 1 dm3. To increase the TAA of the water extract of GPS, an aqueous extract of dried flowers of elmberry (Filipendula ulmaria (L.) Maxim) was used, obtained in a similar way. The TAA of water extracts of GPS as the labasnik extract was added increased to its content of 30 % wt., and the effects of synergy (TAAexcess) – decreased to 0 (labasnik content of 35 % wt.), passing into antagonism according to the linear equation with a confidence value of approximation R2 0.981. Comparative tests of water extracts of laburnum flowers and GPS in closed containers for storing biological samples at a temperature of +5 °C in the refrigerator showed that the TAA of water extraction of laburnum flowers in g Ru by 1 dm3 from the number of days of its aging decreases according to the linear equation with the approximation confidence value R2 0.927, and GPS increases – R2 0.965.

scholarly journals Biochemical study of hepatoprotective collection of plant origin

2019 ◽  
Vol 59 (7) ◽  
pp. 134-141
Author(s):  
Anatoly A. Lapin ◽  
◽  
Irek G. Garifullin ◽  
Valery N. Zelenkov ◽  
◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Liver Diseases ◽  
Biochemical Study ◽  
Water Extract ◽  
Total Antioxidant Activity ◽  
Plant Origin ◽  
Treatment And Prevention ◽  
Total Antioxidant ◽  
The Individual ◽  
Metabolic Regulators

The article presents the results of biochemical studies of the total antioxidant activity of the hepatoprotective collection of plant origin and its individual components, which show that it consists of birch leaves (Betulae folia), tansy flowers (Tanaceti flores), phytohepatol No. 2 (choleretic collection No. 2) and individual its components have pronounced antioxidant activity. More antioxidant activity founded in tansy and true hepatoprotective collection. Comparative tests of the flowers of meadowsweet, with the highest antioxidant activity, showed the promise of their use in the collections of medicinal plants as effective natural metabolic regulators. The total antioxidant activity of the water extract collection at 13.56% rel. exceeded the calculated value obtained by summing the activities of the individual components of the collection, which indicates the presence of synergism in their action, which may be of value for use in the treatment and prevention of liver diseases. When all components of the drug collection are finished, the indicator increases by 11-24 % rel., which indicates the thermal stability of the antioxidant substances that make up their composition. In the oxidation of aqueous extracts of the components of hepatoprotective collection with hydrogen peroxide, the most stable were antioxidants of birch leaves. It was found that collection only at a ratio of 7.7 g per liter of water shows synergism (15 % rel.), and the rest of all the samples we tested are antagonistic. The detected increase in the antioxidant activity of the new collection compared with the effects of its individual components allows us to consider it as a promising dosage form for use in the treatment and prevention of liver diseases.

scholarly journals Aktivitas Antioksidan dan Total Polisakarida Ekstrak Rumput Laut Merah, Hijau dan Coklat dari Pantai Jangkar Situbondo

2019 ◽  
Vol 16 (2) ◽  
pp. 64
Author(s):  
Didin Erma Indahyani ◽  
Depi Praharani ◽  
Izzata Barid ◽  
Ari Tri Wanodyo Handayani
Keyword(s):  
Antioxidant Activity ◽  
Brown Seaweed ◽  
Water Extract ◽  
Ethanol Extract ◽  
Extraction Methods ◽  
Red Seaweed ◽  
Water Extracts ◽  
High Antioxidant Activity ◽  
Polysaccharide Composition ◽  
Ethanol Extracts

The antioxidant activity and polysaccharide composition of seaweed is influenced by species (red, green and brown seaweed), geographical conditions, extraction methods, solvents, temperature and the length of time of extraction. The purpose of this study was to known the total polysaccharide and antioxidant activity in red, green and brown seaweed extracts from Jangkar Situbondo beach. Method. The study was conducted on red, green and brown seaweed extracted with ethanol and water to determine total polysaccharides. Antioxidant analysis uses the method 2,2-diphenyl1-picrylhydrazyl (DPPH) radical. Total polysaccharide and antioxidant activity were observed statistically using two-way ANOVA. The results of this study show that the polysaccharide content in seaweed water extract was significantly higher than ethanol extract, especially in brown seaweed. Seaweed water extracts showed higher antioxidant activity than ethanol extracts. The antioxidant activity of brown seaweed was significantly higher than that of green and red seaweed. Conclusion. Seaweeds have high antioxidant activity in water extracts. Brown seaweed water extract contains high polysaccharides than green and red seaweed. Antioxidant activity in brown seaweed is also higher than in green and red seaweed.

scholarly journals Antioxidant properties of hot water extracts from carpophore and spores of mushroom Ganoderma lucidum

2011 ◽  
pp. 279-288 ◽  
Author(s):  
Anita Klaus ◽  
Maja Kozarski ◽  
Miomir Niksic
Keyword(s):  
Antioxidant Activity ◽  
Ganoderma Lucidum ◽  
Antioxidant Properties ◽  
Water Extract ◽  
Reducing Power ◽  
Hot Water ◽  
Ferrous Ions ◽  
Medicinal Mushrooms ◽  
Water Extracts ◽  
Hot Water Extract

Ganoderma lucidum (Leyss.:Fr.) Karst is one of the medicinal mushrooms, which possesses enviable antioxidant properties. Objective of this investigation was to evaluate antioxidant activity, reducing power, scavenging abilities on 1.1-diphenyl-2-picrylhydrazyl (DPPH) radicals and chelating effects on ferrous ions of hot water extracts obtained from carpophore and spores of this mushroom. Hot water extract from carpophore (Gl-I) showed high antioxidant activity of 85.7 ? 0.7%, at 10 mg/ml, while antioxidant activity of hot water extract from spores (Gl-Is) was 9.2 ? 0.3% at 10 mg/ml. Reducing power of Gl-I reached a plateau of 3.4 ? 0.1 at 20 mg/ml, and 0.3 ? 0.0 at 20 mg/ml for Gl-Is. At 10 mg/ml, scavenging ability on DPPH radicals of Gl-I increased to 96.8 ? 2.5%, whereas Gl-Is scavenged DPPH radicals by 69.6 ? 2.5% at 10 mg/ml. Gl-I chelated 81.6 ? 3.6 % of ferrous ions at 20 mg/ml, while the chelating effect of Gl-Is was 73.8 ? 1.7%. The antioxidative activities of hot water extracts from carpophore and spores of the mushroom G. lucidum were concentration dependent and increased with an increase in the concentration.

scholarly journals Variation in antioxidant activity at two ripening stages of wild mango, Spondias pinnata (L.f.) Kurz., an underutilized fruit

2020 ◽  
Vol 7 (4) ◽  
Author(s):  
Bince Mani ◽  
Sinjumol Thomas
Keyword(s):  
Nitric Oxide ◽  
Hydrogen Peroxide ◽  
Antioxidant Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Total Antioxidant Activity ◽  
Plant Origin ◽  
Nitric Oxide Radical ◽  
Total Antioxidant

Antioxidant compounds play a significant role in preventing and scavenging free-radicals by reducing oxidative stress and providing protection to humans against degenerative diseases and infections. Obviously, antioxidant molecules of plant origin are pivotal to combat the oxidative harm in cells. Present work intended to evaluate the antioxidant capacity of the fruits of Spondias pinnata. Methanol extracts of the fruits at two stages of maturity were prepared and investigated by various antioxidants analyses such as total antioxidant activity, reducing power and radical scavenging assays (DPPH, nitric oxide and hydrogen peroxide). Its total phenol, flavonoid and tannin contents were also determined. Spondias pinnata fruit extracts exhibited effective antioxidant activity and its IC50 values of the unripe fruits were 65, 66, 72.23, 83.25, 66.75 ?g/ml and ripe fruits were 124.24, 92.50, 97.66, 144.10, 72.25 ?g/ml, for total antioxidant activity, reducing power, DPPH radical scavenging, nitric oxide radical scavenging and hydrogen peroxide scavenging assays respectively. The extracts, especially unripe fruit extract had good amounts of total phenolic and flavonoid contents which might contribute the antioxidant activities considerably. It is evident from the study that the fruits of S. pinnata possessed potent antioxidant activity and it can be considered as a good dietary choice among the underutilized fruits as well as common fruits. Therefore, wild mango may be a good choice of antioxidants of plant origin for dietary and pharmaceutical uses.

scholarly journals Antioxidant potential of some Sudanese medicinal plants used in traditional medicine

2015 ◽  
Vol 3 (2) ◽  
pp. 192 ◽  
Author(s):  
Hatil EL-Kamali ◽  
Sana E. M. Hamed
Keyword(s):  
Antioxidant Activity ◽  
Medicinal Plants ◽  
Antioxidant Activities ◽  
Radical Scavenging ◽  
Punica Granatum ◽  
In Vitro Models ◽  
Water Extracts ◽  
Total Antioxidant ◽  
Sudanese Medicinal Plants

<p>In the present work methanolic and water extracts of 19 medicinal plants, commonly used in Sudanese folk medicines against gastrointestinal tract, infectious diseases were investigated for their antioxidant activity. Antioxidant assays were carried out by using different in vitro models such as DPPH (2, 2-diphenyl-1picrylhydrazyl) radical scavenging and Iron chelating activity. Methanolic and water extracts of <em>Punica granatum </em>showed the highest total antioxidant activity of 71±0.03 and 73±0.01 respectively. The antioxidant activities of water extracts were poor when compared to the methanol extract. The iron chelating power of methanol and aqueous extracts of <em>Commiphora myrrha</em> 58±0.01 and <em>Azadirachta indica</em> 57±0.20 respectively.</p>

scholarly journals Evaluation of Polyphenolics Content and Antioxidant Activity in Edible Wild Fruits

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Sharui Shan ◽  
Xuming Huang ◽  
Munir H. Shah ◽  
Arshad Mehmood Abbasi
Keyword(s):  
Antioxidant Activity ◽  
Water Extract ◽  
Local Communities ◽  
Acetone Extract ◽  
Medicinal Uses ◽  
Significant Potential ◽  
Wild Fruits ◽  
Total Antioxidant ◽  
Basic Source ◽  
Rubus Ellipticus

Plant diversity is a basic source of food and medicines for the local communities of the Himalayas. Current study was intended to assess polyphenolics content and antioxidant potential in edible wild fruits used as food and to treat various diseases by the inhabitants of Himalayan region of Pakistan. The fruits of 20 plant species were evaluated using standard protocols, whereas information on medicinal uses was gathered through semistructured interviews. Comparatively,Prunus domesticaandRubus ellipticusfruits exhibited highest levels of phenolics and flavonols contents (113.55 ± 0.61 mg GAE/100 g and 200.06 ± 1.57 mg RtE/100 g FW, respectively) in acetone extract. Nevertheless, flavonoids were maximum in the water extract ofRosa moschata(194.82 ± 3.46 mg RtE/100 g FW). Contrary,Duchesnea indicafruit depicted significant potential to scavenge DPPH and H2O2radicals at 94.66 ± 8.89% in acetone extract and 83.54± 9.37% in water extract, while acetone extract ofRubus ellipticushad maximum potential to reduce ferric ions (133.66 ± 15.00µM GAE/100 g FW). Additionally, total antioxidant capacity was highest in the acetone extract ofBerberis lyciumfruit (332.08 ± 21.90µM AAE/100 g FW). The relationships between polyphenolics and antioxidant activity revealed synergistic role of secondary metabolites in the prevention of diseases. Our study revealed that wild fruits consumed by the local communities of Himalayas are rich in health beneficial phytochemicals and hold significant potential to treat chronic diseases, particularly associated with free radicals.

scholarly journals Antioxidant activity of Trachystemon orientalis (L.) G. Don (Borage) grown and eaten as food in Ordu, Turkey

2015 ◽  
Vol 61 (4) ◽  
pp. 40-51 ◽  
Author(s):  
Melek Col Ayvaz
Keyword(s):  
Antioxidant Activity ◽  
Natural Products ◽  
Total Antioxidant Capacity ◽  
Water Extract ◽  
Ethanol Extract ◽  
Total Phenolic ◽  
Synthetic Antioxidants ◽  
Total Antioxidant ◽  
Phenolic And Flavonoid

SummaryIntroductıon: Instead of synthetic antioxidants, using of natural products with antioxidant activity is demanded.Objectıve: The aim of this study is to evaluate the antioxidant activity and total phenolic and flavonoid contents of theTrachystemon orientalis(borage) obtained from Ordu.Methods: The water and ethanol extracts of the borage plant were investigated by using severalin vitroantioxidant activity tests such as total antioxidant capacity, O2•−,•OH, DPPH and ABTS radicals scavenging activities, hydrogen peroxide scavenging activity, FRAP, Fe2+chelating and reducing power assays in order to make effective comparisons.Results: Water extract of theT. orientalishad the more phenolic (90 mg GA/g extract) and flavonoid (56.88 mg CT/g extract) contents than ethanol extract. Furthermore, both of the extracts showed strong antioxidant and radical scavenging activities determined by differentin vitromodels. The highest total antioxidant capacity as ascorbic acid equivalents of 244.50 mg/g extract was also calculated for water extract. Generally, a relationship between total phenolic content and antioxidant activity was established. It is also an important finding for an edible food source that the phenolic and flavonoid content and antioxidative activities for water extract was higher than the ethanol extract.Conclusıon:T. orientaliscould be used as a food ingredient instead of synthetic antioxidants and all results will contribute to the recent increase in investigations on using natural products in many areas such as food, pharmacy, alternative medicine and natural therapy.

scholarly journals The study of the antioxidant activity of the antiulcerous plant composition and its components

2019 ◽  
Vol 60 (10) ◽  
pp. 60-66
Author(s):  
Ekaterina V. Ferubko ◽  
◽  
Valery N. Zelenkov ◽  
Tamara D. Dergaeva ◽  
Anatoly A. Lapin ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Biochemical Study ◽  
Medical Science ◽  
Total Antioxidant Activity ◽  
Plant Origin ◽  
Polygonum Aviculare ◽  
Treatment And Prevention ◽  
Mountain Ash ◽  
Total Antioxidant ◽  
The Individual

At present, the expansion of research to find sources for obtaining new effective and safe medicines of plant origin, including those used in gastroenterological practice, is a pressing task of medical science, considering that the range of medicinal plant drugs used in practical health care is more than 40%. The article presents the results of biochemical study of total antioxidant activity of anti-ulcer collection of plant origin and its individual components. We show that it consists of the leaves of the planter large (Plantago major L.), grass of a sushchenitsa uliginose (Gnaphalium uliginosum L.), rhizomes and roots of the devisil high (Inula helenium L.), flowers of the chamomile pharmacy (Matricaria chamomilla L.), the roots of licorice naked (Glycyrrhiza glabra L.), grass of bird's mountain (Polygonum aviculare L.), leaves of the nettle (Urtica dioica L.), fruits of a mountain ash ordinary (Sorbus aucuparia L.) and its individual components have pronounced antioxidant activity. The greatest activity was found in the roots of licorice naked, grass of bird 's mountain and flowers of chamomile pharmacy. Total antioxidant activity of water extraction of collection recovery at 6.34% from exceeded the calculated value obtained by summing the activities of the individual components of the collection, which indicates the presence of synergy in their action, which may be of importance for use in the treatment and prevention of diseases in gastroenterological practice. The detected increase in the antioxidant activity of the new collection compared to the effects of its individual components allows it to be considered as a promising dosage form for the treatment and prevention of gastroenterological diseases.

scholarly journals SYNERGISM TEST OF DATE (PHOENIX DACTYLIFERA L.) AND RAW TEMPE ON ANTIOXIDANT ACTIVITY

2021 ◽  
Vol 4 (IAHSC) ◽  
pp. 127-137
Author(s):  
Intan Kurnia Putri ◽  
Aynna Sufana Rani
Keyword(s):  
Antioxidant Activity ◽  
Synergistic Effect ◽  
Phoenix Dactylifera ◽  
Test Methods ◽  
Test Method ◽  
Antioxidant Compounds ◽  
Prospective Data ◽  
Phoenix Dactylifera L ◽  
Total Antioxidant ◽  
High Antioxidant Activity

Introduction: Dates and tempeh are foods that both contain antioxidant compounds. Antioxidant compounds such as flavonoids and isoflavones are known to be found in dates and tempeh. This study was conducted to see how much antioxidant activity contained in dates and tempeh and how the effect of dates and tempeh consumed simultaneously on the increase in total antioxidant activity. Method: This study uses a direct experimental design with prospective data collection. The selected samples were dates with the type of sukkari and tempeh wrapped in plastic. Data processing was carried out using a simple linear regression statistical method. Results: The DPPH test method with UV-Visible Spectrophotometry  instrument  showed the results  of  the % inhibition value of dates fruit of 39.99% and tempeh of 24.52%. Testing the synergistic effect using 7 treatments showed that the treatment with a ratio of 50:50 had a higher % inhibition value than the other treatments, which showed that consuming dates and tempeh in a ratio of 50:50 could provide a synergistic effect on antioxidant activity. Conclusion The results obtained indicate that both samples, both dates and tempeh have high antioxidant activity, consuming both simultaneously can increase antioxidant activity. So it can be concluded that there is an effect on the synergistic effect of antioxidant activity of dates and tempeh which are consumed simultaneously. It is recommended to conduct research on the antioxidant activity of dates and tempeh using other test methods, and further research on the formulation of the preparation or clinical trials using mice.

scholarly journals Novel Extract from Beetle Ulomoides dermestoides: A Study of Composition and Antioxidant Activity

Antioxidants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1055
Author(s):  
Nina A. Ushakova ◽  
Efim S. Brodsky ◽  
Olga V. Tikhonova ◽  
Alexander E. Dontsov ◽  
Maria V. Marsova ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Aqueous Extract ◽  
Dry Matter ◽  
Water Extract ◽  
Water Soluble ◽  
Biologically Active ◽  
Plasma Dynamic ◽  
Darkling Beetle ◽  
Dynamic Extraction ◽  
High Antioxidant Activity

A biologically active extract from the darkling beetle Ulomoides dermestoides was obtained using the electro-pulse plasma dynamic extraction method. The beetle water extract contained a complex of antioxidant substances such as antioxidant enzymes and nonprotein antioxidants, as well as a complex of heat shock antistress proteins. This determines the rather high antioxidant activity of the aqueous extract of the beetle, i.e., 1 mg of dry matter/mL of the extract has an equivalent antioxidant activity to 0.2 mM Trolox (a water-soluble analog of vitamin E). It was shown that the beetle extract can lead to a 25–30% increase in the average lifespan of nematode Caenorhabditiselegans, under normal conditions, and a 12–17% increase under conditions of oxidative stress (with paraquat), and significantly inhibits the fructosylation reaction of serum albumin. Therefore, the beetle aqueous extract shows promise as a biologically active complex exhibiting antioxidant activity.

Sign in / Sign up

Export Citation Format

Share Document