The Immunostimulatory Effects of Ethanolic Extract of Cassia alata on Immune System of Albino Rats Dosed with Staphylococcus aureus (NCIB 8588)

2007 ◽  
Vol 2 (2) ◽  
pp. 200-204 ◽  
Author(s):  
M.K. Oladunmoye
Keyword(s):  
Staphylococcus Aureus ◽  
Immune System ◽  
Ethanolic Extract ◽  
Albino Rats ◽  
Cassia Alata

scholarly journals Phytochemical and Antibacterial Screening of Euphorbia thymifolia Linn and Cassia alata Linn Species in the Province of Abra, Philippines: An Alternative Source of Antibiotics

2016 ◽  
Vol 26 (1) ◽  
Author(s):  
Nero M. Paderes ◽  
Divinia Borgona Eloisan
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Properties ◽  
Ethanolic Extract ◽  
Phytochemical Analysis ◽  
Alternative Source ◽  
Cassia Alata ◽  
Antibacterial Screening ◽  
Ethanolic Extracts

Plants have been aiding humanity around the world by serving as an abundant source of valuable drugs, antibiotics, nourishment, spices, seasonings, dyes, and other commercial and industrial products. The study investigated the antibacterial activity and phytochemical screening of Cassia alata Linn and Euphorbia thymifolia Linn ethanolic extracts against Staphylococcus aureus and Escherichia coli. The research was laid out using Complete Randomized Design (CRD) which was replicated three times. Varying concentrations of Cassia alata Linn and Euphorbia thymifolia Linn ethanolic extracts at 75%, 50% and 25% concentrations were utilized for the antimicrobial assay using the Kirby Bauer method. Phytochemical analysis revealed the presence of phenolics in both plants and some other bioactive components that have been found in vitro to have antibacterial properties. Statistical analysis using ANOVA and DMRT at .05 level of significance shows that among the two plants tested, Euphorbia thymifolia Linn ethanolic extract at 75% concentration exhibited a significant mean diameter of zone of inhibition against Staphylococcus aureus and Escherichia coli. Further laboratory analysis and testing should be conducted through the Bureau of Food and Drugs (BFAD) for further confirmatory results.

scholarly journals A Novel Antimicrobial Phenanthrene Alkaloid from Bryopyllum pinnatum

2011 ◽  
Vol 8 (3) ◽  
pp. 1456-1461 ◽  
Author(s):  
Donatus Ebere Okwu ◽  
Fred Uchenna Nnamdi
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Candida Albicans ◽  
Aspergillus Niger ◽  
Ethanolic Extract ◽  
Klebsiella Pneumonia ◽  
Antimicrobial Studies ◽  
Prevention And Treatment ◽  
Kalanchoe Pinnata ◽  
Isolated Compound

Phenenthrene alkaloid identified as 1-ethanamino 7 hex-1-yne-5I-one phenanthrene was isolated from the ethanolic extract of the leaves ofBryophyllum pinnatum(syn. B. calcinum kalanchoe pinnata) a versatile Nigeria medicinal plant. The structure was elucidated using NMR, IR, UV and MS spectral data. Antimicrobial studies showed that the isolated compound successfully inhibitedPsuedomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli, Candida albicansandAspergillus niger. This result authenticates the use ofbryophyllum pinantumin phytomedicine for disease prevention and treatment of infections.

scholarly journals Protective Effect of Ethanolic Extract ofTabernaemontana divaricata(L.) R. Br. against DEN and Fe NTA Induced Liver Necrosis in Wistar Albino Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Kannappan Poornima ◽  
Palanisamy Chella Perumal ◽  
Velliyur Kanniappan Gopalakrishnan
Keyword(s):  
Ethanolic Extract ◽  
Treated Group ◽  
Hepatic Necrosis ◽  
Hepatoprotective Activity ◽  
Albino Rats ◽  
Protective Effects ◽  
Liver Necrosis ◽  
Standard Drug ◽  
Tabernaemontana Divaricata ◽  
Wistar Albino Rats

This study is an attempt to evaluate the hepatoprotective activity ofTabernaemontana divaricataagainst DEN and Fe NTA induced liver necrosis in rats. Ethanolic extract of the whole plant ofTabernaemontana divaricataat doses of 200 and 400 mg/kg body weight and 5-fluorouracil (standard drug) was orally administered to male Wistar Albino rats once daily for 24 weeks, simultaneously treated with the carcinogen DEN and Fe NTA. In simultaneously treated animals, the plant extract significantly decreased the levels of uric acid, bilirubin, AST, ALT, and ALP in serum and increased the levels of liver marker enzymes in liver. Treatment with the extracts resulted in a significant increase in the levels of antioxidants accompanied by a marked reduction in the levels of malondialdehyde when compared to DEN and Fe NTA treated group. When compared with 200 mg/kg bw rats, 400 mg/kg bw rats and 5-fluorouracil treated rats showed better results in all the parameters. The histopathological studies confirmed the protective effects of extract against DEN and Fe NTA induced liver necrosis. Thus, it could be concluded that the use ofTabernaemontana divaricataextract in the treatment of carcinogen induced hepatic necrosis.

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