scholarly journals Primary Epithelioid Sarcoma Manifesting as a Fungating Scalp Mass - Imaging Features and Treatment Options. A Case Report and Literature Review

2021 ◽  
Vol 15 (11) ◽  
pp. 1-9
Author(s):  
Yonghao Zhang ◽  
Tarun Mohan Mirpuri ◽  
Chi Long Ho
Keyword(s):  
Case Report ◽  
Adjuvant Radiotherapy ◽  
Multimodality Imaging ◽  
Treatment Options ◽  
Epithelioid Sarcoma ◽  
Distant Metastases ◽  
Imaging Features ◽  
Rare Malignancy ◽  
Scalp Mass

Primary epithelioid sarcoma is an extremely rare malignancy of the scalp. To date, less than a dozen such cases have been reported in the literature. The diagnosis often is a challenge to both radiologists and clinicians. This is largely attributed to the lack of literature on the imaging features of scalp epithelioid sarcoma. In this report, we highlight the role of multimodality imaging in the diagnosis of primary scalp epithelioid sarcoma and review the epidemiology, imaging, treatment options, and prognosis of these malignant scalp tumors. Displaying a multilobulated morphology, heterogeneous enhancement, and restricted diffusion on MRI, these tumors typically show central degeneration with hemorrhage, necrosis, and calcification. Wide surgical resection and adjuvant radiotherapy are the mainstays of treatment for localized scalp tumors. Nevertheless, the prognosis of patients with distant metastases at diagnosis is extremely poor compared to those with local or regional diseases.

Metastatic Thymic Carcinoid: A Case Report

2005 ◽  
Vol 71 (7) ◽  
pp. 578-580 ◽  
Author(s):  
Charles C. Talton ◽  
Judith O. Hopkins ◽  
Bruce D. Walley ◽  
Edward H. Kincaid
Keyword(s):  
Case Report ◽  
Kinase Inhibitor ◽  
Cushing Syndrome ◽  
Distant Metastases ◽  
Surgical Excision ◽  
Malignant Potential ◽  
Thymic Carcinoid ◽  
Complete Surgical Excision ◽  
Neuroendocrine Carcinomas

Thymic neuroendocrine carcinomas (carcinoid) are rare tumors. They have malignant potential, the capacity for distant metastasis, and often present with associated endocrinopathies. This report describes a patient who was diagnosed with thymic carcinoid and Cushing syndrome at age 19 that, despite complete surgical excision of his tumor, developed local recurrence with distant metastases to his brain, lungs, and bone. We discuss the evolution of this patient's illness as well as the therapies used in his care. Due to the nature of these tumors to recur both locally and distant, the importance of aggressive surgical management is emphasized. We also discuss the role of adjuvant therapy, which in our case consisted of chemotherapy, radiotherapy, and several new therapies including an antiangiogenesis agent and a tyrosine kinase inhibitor.

scholarly journals The radiation therapy options of intracranial hemangiopericytoma: An overview and update on a rare vascular mesenchymal tumor

2018 ◽  
Author(s):  
Maria Paola Ciliberti ◽  
Rosa D'Agostino ◽  
Laura Gabrieli ◽  
Anna Nikolaou ◽  
Angela Sardaro
Keyword(s):  
Surgical Resection ◽  
Adjuvant Radiotherapy ◽  
Therapeutic Option ◽  
Treatment Options ◽  
Distant Metastases ◽  
Complete Resection ◽  
Complete Surgical Resection ◽  
Hypervascular Tumor ◽  
The Central Nervous System ◽  
Radiotherapy Treatment

Hemangiopericytoma (HPC) is an extremely rare hypervascular tumor of mesenchymal lineage. It tends to recur and to develop distant metastases even many years after primary surgical resection. The management of recurrent and metastatic disease is not always so well defined. A complete surgical resection does not eliminate the high risk of local recurrences that occur in the central nervous system, often in the same surgical bed. However, treatment with adjuvant radiotherapy even in cases of complete resection remains controversial. Because of its rarity, there is no standard for treatment. We focused on radiotherapy treatment options, analyzing the literature and making a base on conduct further studies to establish the standard radiation dose to be used for locoregional control of such a complex and extremely rare disease and to help specialists to take the most appropriate therapeutic option.

Diagnosis of Metastatic Breast Cancer—A Case Report Using Molecular Cancer Classification

2011 ◽  
Vol 07 (02) ◽  
pp. 116
Author(s):  
Yogesh Gandhi ◽  
Sunil Gandhi ◽  
◽  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Effective Treatment ◽  
Cancer Diagnosis ◽  
Treatment Options ◽  
Metastatic Breast ◽  
Complete Response ◽  
Molecular Profiling ◽  
History Of

An accurate cancer diagnosis is critical as it can direct the use of site-directed, and potentially more effective, treatment options for specific types of cancer. A differential or uncertain diagnosis could prevent cancer patients from receiving optimal treatment, thus affecting their overall prognosis. Advances in molecular technology have led to the development of molecular cancer classifiers that can direct or confirm the diagnosis of metastatic cancers which would otherwise be considered uncertain or unknown. This case report describes the role of molecular diagnostics in the evaluation of a patient with a large pancreatic mass and a history of breast cancer. Results from a 92-gene molecular profiling assay (CancerTYPE ID®) predicted that this new mass was breast cancer. This diagnosis allowed for effective treatment and complete response in this patient.

scholarly journals Malignant Fibrous Histiocytoma of the Kidney Treated with Nephrectomy and Adjuvant Radiotherapy: A Case Report

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Rita Marchese ◽  
Pantaleo Bufo ◽  
Giuseppe Carrieri ◽  
Giuseppe Bove
Keyword(s):  
Case Report ◽  
High Risk ◽  
Adjuvant Chemotherapy ◽  
Local Recurrence ◽  
Malignant Fibrous Histiocytoma ◽  
Adjuvant Radiotherapy ◽  
Poor Prognosis ◽  
Fibrous Histiocytoma ◽  
Distant Metastases ◽  
Survival Outcome

Malignant fibrous histiocytoma (MFH) usually presents in the extremities or retroperitoneum. Cases involving the kidney are rare and portend a poor prognosis. Although radical nephrectomy is the most beneficial curative choice for this neoplasm, patients are often treated with adjuvant chemotherapy due to high risk of local recurrence and distant metastases. We describe a case of a 68-year-old woman affected by MFH, treated with both nephrectomy and radiotherapy without systemic therapy showing an unexpected twenty-four-month postsurgery survival outcome.

scholarly journals A case report of a primary cardiac lymphoma causing superior vena cava obstruction: the value of multimodality imaging in the clinical workup

2020 ◽  
Author(s):  
Alessia Azzu ◽  
Alexios S Antonopoulos ◽  
Batool Almogheer ◽  
Raad H Mohiaddin
Keyword(s):  
Case Report ◽  
Cardiac Magnetic Resonance ◽  
Magnetic Resonance ◽  
Multimodality Imaging ◽  
Superior Vena ◽  
Vena Cava ◽  
Treatment Decisions ◽  
Imaging Features ◽  
Cardiac Lymphoma ◽  
Primary Cardiac Lymphoma

Abstract Background This is a case report of a primary cardiac lymphoma with an unusual clinical presentation. We hereby illustrate the characteristic features of cardiac lymphomas by multimodality imaging and particularly cardiac magnetic resonance (CMR) that can help reach a timely diagnosis non-invasively and guide treatment decisions. Case summary A 58-year-old woman, without significant past medical history, presented with a 3-week history of shortness of breath associated with facial and neck swelling. Transthoracic echocardiogram confirmed the presence of a cardiac mass in the right atrium. Cardiac magnetic resonance helped to characterize the mass, assess its haemodynamic significance and relation to cardiac structures, and reach a non-invasive diagnosis that was crucial for guiding treatment decisions and interventions. Discussion Cardiac masses have distinct imaging features that can help differentiate malignant from benign cardiac tumours. More specifically, primary cardiac lymphomas can be relatively easy diagnosed by CMR in most cases thanks to their characteristic imaging appearance.

scholarly journals Multimodality Imaging Features of Cardiac Fungal Infection: A Case Report

2019 ◽  
Vol 3 (4) ◽  
pp. 125
Author(s):  
Norain Talib ◽  
Yusri Mohammed ◽  
Sharipah Intan S. SY. Abas ◽  
Kama Azira Awang Ramli
Keyword(s):  
Case Report ◽  
Fungal Infection ◽  
Multimodality Imaging ◽  
Imaging Features

An extremely rare epithelioid sarcoma arising from the infratemporal fossa: a case report and literature review

2021 ◽  
Vol 16 ◽  
Author(s):  
Weiming Ran ◽  
Wei Tang ◽  
Junyan Duan ◽  
Jiao Qing ◽  
Zhaohua Zhai
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Head And Neck ◽  
Imaging Techniques ◽  
Infratemporal Fossa ◽  
Epithelioid Sarcoma ◽  
The Body ◽  
Imaging Features ◽  
Anatomic Structure ◽  
Medical College

Introduction: Epithelioid sarcoma (ES) is a rare histopathological type of soft tissue sarcoma. They are subcutaneous soft tissue masses that tend to arise in extremity sites (the classic type, formerly referred to as distal type) or proximal midline region of the body (the proximal type), such as the perineum, genital tract, and pelvis. The head and neck regions are rarely affected by ES, but the infratemporal fossa (ITF) is extremely rare. ES involving the ITF has not been reported before in literature. In this paper, the imaging features of ES were reviewed in detail, and the anatomical structure and epidemiology of ITF were briefly introduced. Sources: We performed a systematic search from 3 databases, CNKI(China National Knowledge Internet), FMRS(Foreign Medical Literature Retrieval Service, Shenzhen METSTR Technology CO., Led. China), and PubMed, to obtain literature from January 1970 to July 2020. Epithelioid sarcoma, head and neck regions, infratemporal fossa, diagnostic imaging, anatomy, MRI, and CT were used as keywords for advanced retrieval. A study had to be found eligible for inclusion to be closely related to ES and/or ITF. A total of 129 related pieces of literature were retrieved successfully, of which 37 were closely related to this study. The case report in this article is from the Affiliated Hospital of North Sichuan Medical College. The present study was approved by the institutional review board of the Affiliated Hospital of North Sichuan Medical College and a written informed consent for the publication of the case was obtained from the patient. Case Presentation: A 33-year-old man accidentally found a slowly growing, painless mass in the left cheek more than a month ago. On plain computed tomography (CT) scan of the outpatient department, an oval slightly low-density mass with well-defined and uniform boundary in the infratemporal fossa was revealed, and on the contrast-enhanced scan, it was homogeneous and moderately enhanced. Initially, the CT appearance favored benign lesions. However, the possibility of a malignant tumor can not be excluded completely. Finally, the patient was referred to the inpatient department a tumor arose from IF and underwent a selective operation. The tumor was completely removed. Histologic findings were compatible with epithelioid sarcoma. Post-operatively, the patient received 2 cycles of radiotherapy, and there was no evidence of recurrence after 6 months follow-up. Conclusion: The imaging manifestations of ES are various. The anatomic structure of ITF is complex and the pathological types are various. It should be very careful in the qualitative diagnosis of tumors from the ITF, and advanced imaging techniques will be useful in imaging diagnosis.

Abdominal desmoid-type fibromatosis – a case report and an overview of treatment options

Nowa Medycyna ◽  
2018 ◽  
Vol 25 (2) ◽  
Author(s):  
Justyna Koszarska-Mirek ◽  
Jakub Orleański
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Abdominal Wall ◽  
Treatment Options ◽  
Fibrous Tissue ◽  
Distant Metastases ◽  
Desmoid Tumour ◽  
Recurrence Rates ◽  
Abdominal Organs ◽  
Appropriate Treatment

Fibromatosis (desmoid, desmoid tumour) is a tumour belonging to the group of fibrous tissue proliferative diseases. Although the tumour cannot produce distant metastases, it shows local malignancy by invading adjacent tissues, as well as high recurrence rates after local resection. The incidence of fibromatosis is 2-4 cases per 1 million inhabitants per year. Three types of fibromatosis have been distinguished: extra-abdominal, abdominal wall and intra-abdominal type. Although the most common types are sporadic, coexistence with familial adenomatous polyposis (FAP), known as the Gardner’s syndrome, is observed. Available therapeutic options include surgical treatment, watchful waiting, hormone therapy, non-steroid anti-inflammatory drugs, chemotherapy and radiation therapy. This case report aims to draw attention to the difficulties in selecting an appropriate treatment option, limited surgical treatment, the psychological aspect of the disease, as well as the need to actively search for modern diagnostic and therapeutic solutions. We present a case of a 26-year-old patient who was ultimately diagnosed with a desmoid tumour invading the abdominal wall and internal abdominal organs. The patient presented to a county hospital due to suspected gastrointestinal obstruction. It was found from medical history that the patient had palpated a tumour of the abdominal wall 9 months before admission.

CAM Management of Peripheral Arterial Occlusive Disease (PAOD): A Case Report

2008 ◽  
Vol 13 (3) ◽  
pp. 198-203 ◽  
Author(s):  
Sanjeev Rastogi
Keyword(s):  
Case Report ◽  
Peripheral Arterial Occlusive Disease ◽  
Single Case ◽  
Treatment Options ◽  
Arterial Occlusive Disease ◽  
Occlusive Disease ◽  
Rapid Progression ◽  
Disease Cost ◽  
Peripheral Arterial

Peripheral Arterial occlusive Disease is one among many conditions where a dependable cure is still elusive. Despite of availability of various treatment options on medical and surgical grounds, these many options does not with stand to the complexity, generalization and rapid progression inherent to the disease. Cost of diagnosis and cost of therapy also acts as a constraint in its quick management. In these conditions, any CAM approach addressing to all these intricacies of PAOD is a welcoming thought. We tried to intervene with CAM therapy in a patient diagnosed as having PAOD. The clinical improvements observed in this single case are warranting for more serious studies to define the role of CAM in these conditions.

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