Suborbital Spaceflight

Author(s):  
Gerold F. L. Fuchs

One of the major historical milestones of spaceflight, suborbital flights played a vital role in the development of technologies and procedures for the operation of spacecraft. Today suborbital flights still play an important part in scientific and commercial fields, and in this chapter, the basic terms and values will be defined and also explained in the historical context. Small launching system for scientific applications called sounding rockets have a significant importance due to an unbeatable flexibility and cost effectiveness and the new and emerging field of commercial human flights to the edge of space is growing as an economically sound business model for private participants. Either of them will be detailed in the appropriate sub-chapters, followed by an outlook on the future possibilities of suborbital flights.

Author(s):  
Christopher Brooke

This is the first full-scale look at the essential place of Stoicism in the foundations of modern political thought. Spanning the period from Justus Lipsius's Politics in 1589 to Jean-Jacques Rousseau's Emile in 1762, and concentrating on arguments originating from England, France, and the Netherlands, the book considers how political writers of the period engaged with the ideas of the Roman and Greek Stoics that they found in works by Cicero, Seneca, Epictetus, and Marcus Aurelius. The book examines key texts in their historical context, paying special attention to the history of classical scholarship and the historiography of philosophy. The book delves into the persisting tension between Stoicism and the tradition of Augustinian anti-Stoic criticism, which held Stoicism to be a philosophy for the proud who denied their fallen condition. Concentrating on arguments in moral psychology surrounding the foundations of human sociability and self-love, the book details how the engagement with Roman Stoicism shaped early modern political philosophy and offers significant new interpretations of Lipsius and Rousseau together with fresh perspectives on the political thought of Hugo Grotius and Thomas Hobbes. The book shows how the legacy of the Stoics played a vital role in European intellectual life in the early modern era.


2019 ◽  
Vol 66 ◽  
pp. 327-334
Author(s):  
Inga V. Zheltikova ◽  
Elena I. Khokhlova

The article considers the dependence of the images of future on the socio-cultural context of their formation. Comparison of the images of the future found in A.I. Solzhenitsyn’s works of various years reveals his generally pessimistic attitude to the future in the situation of social stability and moderate optimism in times of society destabilization. At the same time, the author's images of the future both in the seventies and the nineties of the last century demonstrate the mismatch of social expectations and reality that was generally typical for the images of the future. According to the authors of the present article, Solzhenitsyn’s ideas that the revival of spirituality could serve as the basis for the development of economy, that the influence of the Church on the process of socio-economic development would grow, and that the political situation strongly depends on the personal qualities of the leader, are unjustified. Nevertheless, such ideas are still present in many images of the future of Russia, including contemporary ones.


Author(s):  
Matthias Albani

The monotheistic confession in Isa 40–48 is best understood against the historical context of Israel’s political and religious crisis situation in the final years of Neo-Babylonian rule. According to Deutero-Isaiah, Yhwh is unique and incomparable because he alone truly predicts the “future” (Isa 41:22–29)—currently the triumph of Cyrus—which will lead to Israel’s liberation from Babylonian captivity (Isa 45). This prediction is directed against the Babylonian deities’ claim to possess the power of destiny and the future, predominantly against Bel-Marduk, to whom both Nabonidus and his opponents appeal in their various political assertions regarding Cyrus. According to the Babylonian conviction, Bel-Marduk has the universal divine power, who, on the one hand, directs the course of the stars and thus determines the astral omens and, on the other hand, directs the course of history (cf. Cyrus Cylinder). As an antithesis, however, Deutero-Isaiah proclaims Yhwh as the sovereign divine creator and leader of the courses of the stars in heaven as well as the course of history on earth (Isa 45:12–13). Moreover, the conflict between Nabonidus and the Marduk priesthood over the question of the highest divine power (Sîn versus Marduk) may have had a kind of “catalytic” function in Deutero-Isaiah’s formulation of the monotheistic confession.


Healthcare ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 834
Author(s):  
Magbool Alelyani ◽  
Sultan Alamri ◽  
Mohammed S. Alqahtani ◽  
Alamin Musa ◽  
Hajar Almater ◽  
...  

Artificial intelligence (AI) is a broad, umbrella term that encompasses the theory and development of computer systems able to perform tasks normally requiring human intelligence. The aim of this study is to assess the radiology community’s attitude in Saudi Arabia toward the applications of AI. Methods: Data for this study were collected using electronic questionnaires in 2019 and 2020. The study included a total of 714 participants. Data analysis was performed using SPSS Statistics (version 25). Results: The majority of the participants (61.2%) had read or heard about the role of AI in radiology. We also found that radiologists had statistically different responses and tended to read more about AI compared to all other specialists. In addition, 82% of the participants thought that AI must be included in the curriculum of medical and allied health colleges, and 86% of the participants agreed that AI would be essential in the future. Even though human–machine interaction was considered to be one of the most important skills in the future, 89% of the participants thought that it would never replace radiologists. Conclusion: Because AI plays a vital role in radiology, it is important to ensure that radiologists and radiographers have at least a minimum understanding of the technology. Our finding shows an acceptable level of knowledge regarding AI technology and that AI applications should be included in the curriculum of the medical and health sciences colleges.


2021 ◽  
Vol 7 (5) ◽  
pp. 921-932
Author(s):  
Zhang Jia ◽  
Xu Hui ◽  
Zeng Zhi ◽  
Yu Jingjing

Objectives: The ban on smoking creates a good smoke-free environment for the traditional farmer’s market. However,the suddenly spread COVID-19 has greatly impacted the business model of the traditional smoke-free farmer’s market.Methods: In order to realize the effective transformation of the current farmer’s market, this paper uses the business model canvas of Osterwalder and Pigneur to compare and analyze the traditional smoke-free farmer’s market and the smart farmer’s market. Results:The study found that the new business model promoted by “Smart Farmer” can effectively solve the difficulties and problems faced by the current farmer’s market. Conclusions:On the basis of this research, this paper puts forward the main direction of the future transformation of the farmer’s market business model, in order to provide a theoretical and practical basis for the intellectualized reconstruction of farmer’s market in China.


2021 ◽  
Vol 2021 (2b) ◽  
pp. 35-40
Author(s):  
I. Stambler ◽  

Celebrating the 30th anniversary of Ukraine's independence, it is important to remember the historical achievements of Ukrainian science, to honor the heroes of the science of the past and to draw inspiration from their achievements for the development of science of the future. In this regard, the history of medicine, as a special academic discipline, plays a vital role an important academic and civic role, as it helps to trace the medical scientific achievements of the past and draw conclusions about their strengths and priorities for future national and international growth and development. Analyzing the scientific strengths and priorities of science and medicine in Ukraine, it is safe to say that biomedical gerontology is one of the most important scientific and historical values and priorities of Ukraine on a global scale. There are good reasons to continue and develop this tradition, building on the strengths that exist, drawing inspiration from the past and looking to the future. Currently, the development of biomedical gerontology is becoming increasingly important for Ukraine, given the rapid aging of the country's population. The resulting economic and social problems are related to the aging population, which puts biomedical gerontology as a discipline that seeks solutions to achieve healthy and productive longevity, at the forefront of social significance, demanding further development and support of this field for the sake of internal national stability, and to preserve the country's international contribution. It is hoped that the outstanding history of biomedical gerontology in Ukraine, its honorable historical place in national development and international cooperation, will inspire further growing support and development of this field in Ukraine and abroad.


2018 ◽  
Vol 61 (2) ◽  
pp. 59-83 ◽  
Author(s):  
Massimo Garbuio ◽  
Nidthida Lin

The future of health care may change dramatically as entrepreneurs offer solutions that change how we prevent, diagnose, and cure health conditions, using artificial intelligence (AI). This article provides a timely and critical analysis of AI-driven health care startups and identifies emerging business model archetypes that entrepreneurs from around the world are using to bring AI solutions to the marketplace. It identifies areas of value creation for the application of AI in health care and proposes an approach to designing business models for AI health care startups.


2018 ◽  
Vol 19 (12) ◽  
pp. 3770 ◽  
Author(s):  
Xianbin Zhang ◽  
Ahmed Abdelrahman ◽  
Brigitte Vollmar ◽  
Dietmar Zechner

Yes-associated protein, a core regulator of the Hippo-YAP signaling pathway, plays a vital role in inhibiting apoptosis. Thus, several studies and reviews suggest that yes-associated protein is a good target for treating cancer. Unfortunately, more and more evidence demonstrates that this protein is also an essential contributor of p73-mediated apoptosis. This questions the concept that yes-associated protein is always a good target for developing novel anti-cancer drugs. Thus, the aim of this review was to evaluate the clinical relevance of yes-associated protein for cancer pathophysiology. This review also summarized the molecules, processes and drugs, which regulate Hippo-YAP signaling and discusses their effect on apoptosis. In addition, issues are defined, which should be addressed in the future in order to provide a solid basis for targeting the Hippo-YAP signaling pathway in clinical trials.


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