Your Personal, Virtual Librarian

Author(s):  
Alexander Krumpholz ◽  
David Hawking ◽  
Tom Gedeon

Searching scientific literature is a common and critical activity for research scientists, students, and professionals such as medical clinicians. These search tasks can be time consuming and repetitive, but literature search and management tools are already making the job much easier. This chapter analyses the literature retrieval process, reviews some currently available tools and elaborates on potential future support for the knowledge worker by an intelligent automated assistant. A special focus of this chapter is the automatic retrieval of medical literature and the exploration of the answer space.

2009 ◽  
Vol 48 (04) ◽  
pp. 371-380 ◽  
Author(s):  
S. Antani ◽  
Rodney Long ◽  
T. M. Deserno

Summary Objectives: An increasing number of articles are published electronically in the scientific literature, but access is limited to alphanumerical search on title, author, or abstract, and may disregard numerous figures. In this paper, we estimate the benefits of using content-based image retrieval (CBIR) on article figures to augment traditional access to articles. Methods: We selected four high-impact journals from the Journal Citations Report (JCR) 2005. Figures were automatically extracted from the PDF article files, and manually classified on their content and number of sub-figure panels. We make a quantitative estimate by projecting from data from the Cross-Language Evaluation Forum (Image-CLEF) campaigns, and qualitatively validate it through experiments using the Image Retrieval in Medical Applications (IRMA) project. Results: Based on 2077 articles with 11,753 pages, 4493 figures, and 11,238 individual images, the predicted accuracy for article retrieval may reach 97.08%. Conclusions: Therefore, CBIR potentially has a high impact in medical literature search and retrieval.


Diagnosis ◽  
2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Diletta Onorato ◽  
Giovanni Carpenè ◽  
Giuseppe Lippi ◽  
Mairi Pucci

AbstractThe worldwide spread of coronavirus disease 2019 (COVID-19) has generated a global health crisis and more than a million deaths so far. Epidemiological and clinical characteristics of COVID-19 are increasingly reported, along with its potential relationship with overweight and/or obesity. Therefore, we aim here to review the current scientific literature on the impact of overweight and/or obesity among hospitalized patients who have developed severe or critical forms of COVID-19. Following PRISMA guidelines, our literature search identified over 300 scientific articles using the keywords “obesity” and “COVID-19”, 22 of which were finally selected for reporting useful information on the association between overweight/obesity and disease severity. In particular, in 11 out of the 14 studies (79%) which evaluated the association between obesity and disease severity providing also a risk estimate (i.e., the odd ratio; OR), the OR value was constantly >2. Although the studies were found to be heterogeneous in terms of design, population, sample size and endpoints, in most cases a significant association was found between obesity and the risk of progressing to severe COVID-19 illness, intensive care unit admission and/or death. We can hence conclude that an increased body mass index shall be considered a negative prognostic factor in patients with COVID-19, and more aggressive prevention or treatment shall hence be reserved to overweight and/or obese patients.


Author(s):  
Rutika, B. Maske

The purpose of this review is to provide the latest information on Down syndrome. The author conducted a literature search of available sources describing the issue of down syndrome with special focus on syndrome and made a comparison and evaluation of relevant findings.The results of this review indicate that Down syndrome (DS) is one of the commonest disorders with huge medical and social cost. DS is associated with number of phenotypes including congenital heart defects, leukemia, Alzeihmer’s disease, Hirschsprung disease etc. DS individuals are affected by these phenotypes to a variable extent thus understanding the cause of this variation is a key challenge. In the present review article, we emphasize an overview of DS, DS-associated phenotypes diagnosis and management of the disease.


2011 ◽  
pp. 1537-1546
Author(s):  
Giovanni M. Sacco

End-user interactive access to complex information is one of the key functionalities of knowledge management systems. Traditionally, access paradigms have focused on retrieval of data on the basis of precise specifications: examples of this approach include queries on structured database systems, and information retrieval. However, most search tasks, and notably those typical of a knowledge worker, are exploratory and imprecise in essence: the user needs to explore the information base, find relationships among concepts, and thin alternatives out in a guided way.


2011 ◽  
Vol 77 (2) ◽  
pp. 135 ◽  
Author(s):  
Vivek Jain ◽  
DeepakK Raut

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Veeraraghavan Meyyur Aravamudan ◽  
Chaozer Er ◽  
Ikram Hussain ◽  
Nicholas wong wai Cheong ◽  
Chong Chern Hao ◽  
...  

Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.


2017 ◽  
Vol 8 (3) ◽  
pp. ar.2017.8.0210 ◽  
Author(s):  
Lauren W. Kaminsky ◽  
Theodore Kelbel ◽  
Fay Ansary ◽  
Timothy Craig

Background Hereditary angioedema (HAE) is a life-long disease that often manifests by puberty. Treatment of attacks is essential to improve quality of life and to decrease morbidity and mortality. During pregnancy, treatment is limited because multiple treatment options, including icatibant, are not approved for use during pregnancy. Objective We report the outcomes of three pregnancies during which icatibant was used by a patient with HAE with normal C1-inhibitor for treatment of attacks. We also reviewed the literature for reports of icatibant use during pregnancy for outcomes and adverse events. Methods We report on a patient who treated herself with icatibant during three separate pregnancies. Postpartum follow-up verified the health of the mother and children. We also performed a complete literature search of medical literature data bases on icatibant use during pregnancy. Results The patient in our report administered multiple doses of icatibant during three pregnancies. The child born from the first pregnancy and the child from the third pregnancy were born at term and without congenital anomalies. The child from the second pregnancy was 1-month preterm. All three children were developmentally normal. The literature search identified two case reports and one abstract of limited icatibant use without adverse events during pregnancy in patients with HAE. These pregnancies resulted in the births of healthy infants. Conclusion From a search of the literature, three cases of icatibant use during pregnancy resulted in healthy infants. In addition, we report that from icatibant use in three separate pregnancies, one infant was born prematurely, but there were no birth defects. From follow-up, the children continued meeting developmental milestones. This report adds to the acquisition of knowledge for drug adverse events during postmarketing surveillance for icatibant use during pregnancy.


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