Chronodisruption and Loss of Female Reproductive Potential Due to Shift Work

Author(s):  
Chandana Haldar ◽  
Jayita Pal Chowdhury

Entrainment of 24 hrs light/dark cycle is nowadays getting altered in corporate sector and even at home due to over exposure to artificial light at night (ALAN) and is commonly denoted as chronodisruption. Chronodisruption interferes with the daily physiology that is regulated by SCN/pineal-melatonin/Hypothalamo-Pituitary axis. In females, reduction in sleep due to shift work desynchronizes HPG-HPA axis induces a stress like condition, accompanied by increased free radical generation in ovary leading to polycystic ovaries, depletion of ovarian reserve, luteal phase defects, endometriosis, implantation failure, etc. Evidence suggest that there is remedial rescue by management of circulatory melatonin due to its chronobiotic/antioxidant/anti-inflamatory/antiapoptotic potentials and its role in ovarian folliculogenesis and steroidogenesis. Advancement in melatonin research suggests that it could be beneficial for commercial use, that is, (1) as an endogenous synchronizer, (2) to improve the quality of oocyte, and (3) for promoting success in the frequency of IVF.

Author(s):  
Osama Mahfooz ◽  
Mujtaba Memon ◽  
Asim Iftikhar

<span>A PLC is a digital computer used to automate electromechanical processes. This research is<span> based on automation of a water tank by using Siemens PLC. Automatic control of water tanks<span> can work continuously and can provide accurate quantity of water in less time. In such process<span> there is no need of labor so there is no human error. Without human error, the quality of product<span> is better and the cost of production would definitely decrease with no error in quantity required.<span> Water level sensing can be implemented in industrial plants, commercial use and even at home<br /><br class="Apple-interchange-newline" /></span></span></span></span></span></span>


1985 ◽  
Vol 10 (3) ◽  
pp. 315-326 ◽  
Author(s):  
K.L.K. Rao ◽  
Ramesh G. Tagat

The paper argues for a new role for rural marketing, namely, that of delivering a better standard of living and quality of life for the rural people. It discusses the role of conflict, corporation, and competition in the modernization of rural society brought by rural marketing. It conceptualizes rural marketing as an interactive activity in which the major participants are the government, voluntary agencies, the corporate sector, and the rural clientele, each with its distinctive activities, mode of operating, and stake.


Vestnik ◽  
2021 ◽  
pp. 1-4
Author(s):  
А.Б. Мукашева ◽  
М.Ш. Шарипова ◽  
Д.Н. Маханбеткулова ◽  
А.Б. Смажан

Актуальность. Беременность и аборты, которые отрицательно сказываются на репродуктивном здоровье и качестве жизни подростков, могут стать серьезной проблемой для репродуктивного потенциала следующего поколения. По мнению многих отечественных исследователей, аборт и ранняя беременность неблагоприятны для девочек-подростков, так как могут не только привести к потенциальным осложнениям для здоровья, но и вызвать серьезные психологические проблемы. Цель исследования. Определить частоту распространенности показателей подростковой беременности и абортов за 2016-2020 гг. по г. Алматы Результаты и обсуждение. По данным Республиканского центра электронного здравоохранения в Алматы, была проведена оценка распространенности беременности и абортов среди подростков за последние пять лет (2016-2020 гг.). Выводы. Анализ показателей беременности и абортов среди девочек-подростков 15-17 лет в Алматы за период 2016-2020 годов показал, что они имеют умеренную тенденцию к снижению. Хотя показатель беременностей в 2020 году составляет 5,8, он выше, чем в развитых странах, таких как Япония и Южная Корея. Pregnancy and abortion, which negatively affect the reproductive health and quality of life of adolescents, can be a serious problem for the reproductive potential of the next generation. According to many domestic researchers, abortion and early pregnancy are unfavorable for adolescent girls, as they can not only lead to potential health complications, but also cause serious psychological problems. Purpose of the study. To determine the frequency of prevalence rates of teenage pregnancy and abortion for 2016-2020. in Almaty Results and discussion. According to the Republican Center for eHealth in Almaty, an assessment was made of the prevalence of pregnancy and abortion among adolescents over the past five years (2016-2020). Findings. Analysis of pregnancy and abortion rates among adolescent girls aged 15-17 years in Almaty for the period 2016-2020 showed that they have a moderate downward trend. Although the pregnancy rate in 2020 is 5.8, it is higher than in developed countries such as Japan and South Korea.


2003 ◽  
Vol 28 (6) ◽  
pp. 831-887 ◽  
Author(s):  
Benoît Mauvieux ◽  
Laurent Gouthière ◽  
Bruno Sesboüe ◽  
Damien Davenne

The aim of this study was to show the resistance and persistence of the circadian rhythm of temperature (T°) and the sleep quality of athletic subjects and sedentary subjects engaged in night work, and attempt to explain the mechanisms that influence these differences. The effects of night work on biological rhythms have been studied extensively in the past few years. The contradictory situations for the night workers irrefutably affect their biological systems. Individuals with high amplitudes in their circadian rhythms have been found to be more tolerant to shift work and this results in a greater stability of circadian rhythms. This seems beneficial in coping with frequent rhythm disturbances. The physical training program seems to improve several mechanisms of the human biological system: amplitudes of circadian rhythms were increased and the circadian rhythm period was more resistant to an environment extreme (night work, shift work, sleep deprivation, or jet lag). To test this hypothesis, athletes and sedentary subjects who were engaged in regular night work were selected in the PSA Peugeot Citroën Automobiles Group in French Normandy country. The circadian rhythm of the T° for both groups was studied with a specific methodology and with extensive spectral analysis, especially the spectral elliptic inverse method. Study models of the rhythm of the T° were determined and the characteristic parameters were exposed. A complementary actigraphic study showed the physical training program's effects on the sleep quality. The results revealed a large stability in the rhythm of circadian variation of T° for the athletes: the amplitude was still large but for the sedentary subjects the amplitude of the T° decreased and it was difficult to adjust a period on the rhythm of T°. The stability and persistent quality of the athletes' circadian rhythm was confirmed. We observed that the actigraphic sleep was greater for athletes than for sedentary subjects, and the acrophase time for the athletes was later than for the sedentary subjects during the night shift. Key words: circadian rhythm of temperature, actimetry, sleep quality, exercise, night work, methodology of rhythms analysis


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Menglin Li ◽  
Yunyun Liu ◽  
Haoran Wang ◽  
Shuzhen Zheng ◽  
Yinhe Deng ◽  
...  

Objective. To systematically evaluate the efficacy and safety of acupuncture for patients with recurrent implantation failure (RIF) undergoing in vitro fertilization-embryo transfer (IVF-ET) and hopefully provide reliable guidance for clinicians and patients. Methods. Through searching domestic and foreign medical journals, the literature of randomized controlled trials (RCTs) of acupuncture for RIF undergoing IVF-ET was collected. RevMan 5.3 software was used for meta-analysis and Cochrane’s risk of bias assessment tool was used to evaluate the quality of the included studies. Results. Seven documents meeting the criteria were finally included. The results showed that the intervention group contributes more in outcomes including clinical pregnancy rate (RR = 1.90, 95% CI (1.51, 2.40), P < 0.05 ), biochemical pregnancy rate (RR = 1.59, 95% CI (1.27, 1.99), P < 0.05 ), embryo implantation rate (RR = 1.89, 95% CI (1.47, 2.45), P < 0.05 ), and endometrial thickness (MD = 1.11, 95% CI (0.59, 1.63), P < 0.05 ) when compared with the control group, and the difference is statistically significant. In terms of the number of embryo transfers and the type of endometrium, the difference between the acupuncture group and the control group was not statistically significant. Conclusion. Acupuncture therapy on patients with RIF can improve the pregnancy outcome of patients. It is a relatively effective treatment with satisfactory safety and suitable for clinical application. However, as the quality of the included studies is not good enough, the conclusion of this meta-analysis should be treated with caution. More double-blind RCTs equipped with high quality and large samples are expected for the improvement of the level of evidence.


2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Mojtaba Elhami Athar ◽  
Mohammad-Kazem Atef-Vahid ◽  
Ahmad Ashouri

2020 ◽  
pp. 74-84
Author(s):  
Yaroslav Tsytsiura ◽  
Yurii Kovalchuk

In the article the results of studying of features of role of trace elements in the formation of the quality indicators of seeds of oilseed radish in two varieties are reflected. Systematized the views of various researchers on the processes of formation of oil content in cruciferous crops in general and radish oilseed in particular, given the current strategy of fertilizer oilseed crops of the family Cruciferae. Studied feature of the stages of the implementation and effectiveness of mono-component micronutrients in the form of easily soluble and readily available substances. The studied set of microelements included the recommended list of physiologically important components of modern microfertilizer formats and their chemical composition in order to optimally analyze the effectiveness of application for their single application in two key phases of oilseed radish – the phenological phase of stalking and the phenological phase of flowering. The use of each of micronutrients was effective and substantial compared to the oil content of seeds of both cultivars of oilseed radish given the level of oil content in seeds in control variant. The magnitude of the variation in the oil index was estimated taking into account the differences in the nature of the hydrothermal regimes of the research period. This allowed to determine the degree of genotypic nature of the formation of the oil content of seeds in oilseed radish and the possibility and effectiveness of selection of appropriate genotypes with the prospect of obtaining oil in the technical direction of use. Also assessed the role of individual micronutrients in the magnitude of the volatility of oil content in seeds of oilseed radish. Determined that the increase of oil content in seeds of oilseed radish the addition of various trace elements in the range of 0.3-1.4% from the close dynamic the resulting effective action on the formation of this indicator in the form of Co>Zn>Cu>B>Mn>Mo. It is proved that the efficacy of these minerals increases with introducing them into the flowering stage, which is a critical period regarding the implementation of the reproductive potential of the plants of oilseed radish and the formation of appropriate indicators of the quality of its seeds. The recommendations for further research in the field of optimization of fertilizer radish seeds and micronutrients were formulated. Key words: oilseed radish, fertilizer, microelements, seed quality, oil content, variety.


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