Experimental Studies of Elastic Properties of Dental Enamel and Photopolymer Used for early Caries Treatment

2013 ◽  
Vol 592-593 ◽  
pp. 358-361
Author(s):  
Anton Y Beliaev ◽  
Olga S. Gileva ◽  
Andrew L. Zuev ◽  
Maria A. Muraveva

The paper is concerned with the study of the elastic properties of dental enamel and its destruction by a microindentation technique. A series of experiments were performed to find differences in the mechanical properties of healthy and diseased dental enamel. It has been found that the times of dental enamel destruction in healthy and carious areas under a constant force are different. The effect of an infiltrated photopolymer on the hardness and elastic modulus of dental enamel was investigated by microindentation testing. A comparative analysis of the features of healthy, damaged by caries and treated by photopolymer enamel was carried out.

2019 ◽  
Vol 10 (3) ◽  
pp. 5-15
Author(s):  
M. L Nuzhdin

Often in construction practice there is a need to strengthen the pile foundation of buildings and structures. The traditional methods include the implementation of additional, as a rule, bored piles with the subsequent erection of a grillage incorporating them into operation. Often, this work has to be done in the conditions of dense urban development, in cramped rooms of the basement, etc., which leads to significant technological difficulties. One of the alternative ways to strengthen pile foundations is the method of high-pressure group injection, which consists in injecting a movable cement-sand mortar into the soil under pressure that exceeds its structural strength. As a result, after its hardening, solid injection bodies are formed at the base, reinforcing the soil base. The article describes the results of experiments to assess the impact of the layout of hard inclusions on the deformability of the soil foundation of the pile foundation model. The experiments were carried out in a small soil tray, which was filled with medium-grained loose sand. The piles were modeled with metal rods, the pile grillage with a metal square stamp. The pile foundation model included 9 piles arranged in a square grid. As injection bodies, gravel grains of various sizes and shapes were used. The studies included 10 series of experiments (each experiment was repeated at least 3 times): the volume of the inclusions used, their sizes, the positioning step in the plan and in depth varied. As a result of the analysis of the performed experiments, conclusions were formulated regarding the purpose of the optimal layout of hard inclusions when strengthening the soil foundation of pile foundations by high-pressure injection of mobile cement-sand mixtures.


2020 ◽  
pp. 87-91
Author(s):  
M. Tymchenko ◽  
Yu. Ivanova ◽  
V. Padalko ◽  
H. Sheremet ◽  
O. Kozlova ◽  
...  

Summary. The aimof the study is to develop a method of sealing the sutured of the small intestine anastomosis in conditions of high risk anastomosis leakege by stopping the inflammation’ cascade in experiment. Materials and methods.The work was experimental in nature, was performed in the SI «ZIGUS NAMSU» in collaboration with the Scientific Research Institute of Biology V. N. Karazin KhNU in the period from 2018 to 2019. To increase the tightness of the intestinal anastomoses applied under conditions of laparatomy, experimental studies were conducted on laboratory animals. The studies were carried out after the permission of the ethics committee SI «ZIGUS NAMSU» in compliance with all ethical requirements for the humane treatment of animals.Surgical operations in two series of experiments were performed under operating conditions under general anesthesia on 10 white sexually mature linear rats – Wistar males, 12-18 months old, weighing about 250 grams. All morphological material (the first and second series of experiments) was marked and fixed in a 10% solution of neutral formalin. Subsequently, paraffin sections were prepared according to the generally accepted histotechnical method and stained with hematoxylin - eosin; according to Van Gieson and Mallory, an immunohistochemical study was used to study microenvironment factors. Results and Discussion. Immunohistochemical examination of the intestine was carried out in several stages, at the first stage we took intestinal tissue during the surgery to form the intestinal anastomosis, before the introduction of allogeneic cell transplants. Also carried out immunohistochemical studies of the emerging mucous membrane at various times after the formation of insolvency of intestinal anastomoses in both studied groups. When using a cell allograft, the mechanisms of repair of the intestinal mucosa include the appearance of cells that carry the expression of markers of mesenchymal and epithelial differentiation (Vim, CD34, CKW, Ecad), and are usually localized in the walls of blood vessels of granulation tissue, as well as in areas of the repairing epithelium. In addition, in the main group, only 7 days after the reaction to cytokeratins (CKW) and Ecad, areas of the repairing epithelium were detected, while the visualization of the epithelium in the control group did not begin even after 10 days. The analysis of immunophenotypes of repairing cells allows us to suggest the participation of mesenchymal-epithelial transformation mechanisms in this process. Conclusions.Thus, studies have shown that the use of cell transplantation of culture of allogeneic cells of the intestine leads to the reconstruction of the intestinal mucosa in a fairly short time. Conducted histological and immunohistochemical studies showed that in the vast majority of animals (77.2%) 10-14 days after the operation, an almost unchanged mucous membrane forms with the preservation of its elasticity.


2020 ◽  
Vol 164 ◽  
pp. 01001
Author(s):  
Alexander Chusov ◽  
Mikhail Shilin ◽  
George Gogoberidze ◽  
Julia Lednova ◽  
Nikolai Bobylev

The goal of the fulfilled research is the study of the influence of the sedimentary suspension from the dredging material on the benthic hydrobionts. In laboratory aquariums six series of experiments were carried out with triple replication on the ability of different benthic organisms to dig out the soil strata due to their periodic burying by marine sand. These experiments were oriented on biota of Eastern Gulf of Finland and the Neva Bay, where a number of deposit sites for dredging material are located presently. Representatives of three main groups of hydrobionts of these areas were selected for experiments – Chironomidae, Gastropoda and Oligochaeta. The ability of different hydrobiont species to overcome the stress effect of the burying under the dredged material was estimated quantitatively. The results show, that the resistance of the studied species to mechanical burying is decreasing in accordance to the scheme: Chironomus plumosus > Melanoides tuberculata > Tubifex tubifex, and depends from the thickness of the layer of dredged material.


The writer first refers to a series of experiments made under the direction of Professor Bache, for the determination of the difference of longitude between New York, Philadelphia and Washington, by means of the magnetic telegraph. By this series of experiments he considers it established that, by means of Morse’s telegraph, two clocks distant from each other 200 miles, can be compared together with the same precision as if they were placed side by side; and that the difference of longitude of two places can be determined with the same precision as the relative error of the clocks. These results were so satisfactory that Professor Bache determined to pro­secute them more extensively, and during the past summer comparisons have been made between New York and Cambridge observatory near Boston. The plan of operation this season was more matured than during the former. The comparisons were all made between a solar chronometer at Cambridge and a sidereal clock at New York. At ten o’clock in the evening, the two observatories having been put in telegraphic communication, when the seconds hand of the solar chronometer came round to 60 s , a signal was given at Cambridge, by pressing the key of the telegraph-register; at the same instant a click was heard at New York, and the time was recorded according to the sidereal clock. At the end of 10 s a second signal was given, which was also recorded at New York; at the end of another 10 s a third signal was given, and so on for sixty seconds. The Cambridge astronomer then commenced beating seconds by striking the key of the telegraph-register in coincidence with the beats of his chronometer. The New York astronomer compared the signals received with the beats of his clock, and waited for a coincidence. When the beats were sensibly synchronous the time was recorded, and the astronomer waited six minutes for another coincidence of beats. The Cambridge astronomer continued beating seconds for fifteen minutes , during which time the New York observer was sure of two coincidences, and might obtain three. When these were concluded, the New York astronomer in the same manner gave signals for one minute at intervals of 10 s , and then beat seconds for fifteen minutes, during which time the Cambridge astronomer obtained four or five coincidences upon his chronometer. This mode of comparison was practised every night, and it is considered that the uncertainty in the comparison of the time-pieces cannot exceed two or three hundredths of a second on any night; and in a series of comparisons the error may be regarded as entirely eliminated. Another mode of comparison which was practised is that of telegraphing star transits. A list of stars which culminate near our zenith at intervals of five or six minutes was prepared, and the observers, both at New York and Cambridge, were furnished with a copy. They then proceeded as follows: Cambridge selected two stars from the list, which we wall call A and B, and struck the key of his register at the instant when the star A passed each of the seven wires of his transit. These signals were heard at New York, and the times recorded. Cambridge then observed the transit of star B in the ordinary manner without telegraphing. New York then observed the transit of star A on his meridian in the usual manner; and struck his key at the instant the star B passed each of the seven wires of his transit, which signals were heard and recorded at Cambridge. The difference of longitude between New York and Cambridge is nearly twelve minutes, affording ample time for all these observations. Thus New York obtained upon his own clock the times of transit of star A over the meridians of Cambridge and New York; and Cambridge obtained upon his chronometer the times of transit of star B over the same meridians. The difference of these times gives the difference of longitude independent of the right ascension of the stars. Both observers then reversed the axis of their transit instruments; Cambridge selected a second pair of stars from the list, and the same series of observations was repeated as with the first pair. The error of collimation was thus eliminated, and by confining the observations to stars within about five degrees of the zenith, the influence of azimuthal error was avoided. The level being read at every reversal, the correction for it was applied by computation. In this manner it is hoped to eliminate every possible source of error, except that which arises from the personal habits of the observers. In order to eliminate this error, a travelling observer worked for a time at Cambridge and compared with the Cambridge astronomer; then came to New York and compared with the New York astronomer; then returned to Cambridge again, and so on as often as was thought necessary. Finally, at the conclusion of the campaign all the observers were to meet at Cambridge and make a general comparison of their modes of observation.


2020 ◽  
Vol 11 (4) ◽  
pp. 5-12
Author(s):  
V. S. Loveikin ◽  
◽  
Yu. O. Romasevych ◽  
O. V. Stekhno ◽  
◽  
...  

The article describes the laboratory model of the tower crane boom system, measuring and recording equipment (sensors, data collection system, power supply, etc.), power control equipment (frequency inverter), and software for data collection and for the frequency inverter control. Planning of experiments for investigation of optimal control of lab model movement was carried out. All experiments are divided into two series: for time optimal control and for control optimal by the integral criterion. For the first series of experiments, the weight of the load (has been varied at three levels) and the length of the flexible suspension (has been varied at two levels) acted as independent factors. For the second series of experiments, one more independent factor was taken into account ‒ the duration of the trolley acceleration (deceleration). This factor has been varied at three levels. The analysis of experimental studies was carried out in terms of variation indicators (deviation of theoretical and experimental data) and graphical dependencies. The results of the analysis showed a sufficiently high convergence of the data obtained during the experiments with those that were obtained by calculation. The existing deviations are caused by the inaccuracy of setting the parameters of the system, the failure to take into account all the significant factors affecting the movement of the system, as well as poor-quality implementation of control with rapid changes in the speed of the trolley movement. Recommendations are given that will eliminate the described factors and ensure further improvement of the technique for implementing optimal control in practice


Author(s):  
G. P. Itkin ◽  
O. Yu. Dmitrieva ◽  
A. S. Buchnev ◽  
A. A. Drobyshev ◽  
A. P. Kuleshov ◽  
...  

Aim.To evaluate the functioning of an implantable pediatric axial pump «DON-3» for bypassing the left ventricle of the heart in experiments on sheep.Materials and methods. Five sheeps at the age of 12–18 months performed paracorporeal installation of the children’s axial pump «DON-3» according to the scheme «left ventricle – aorta».Results.A technique was developed and 5 chronic experiments were conducted on sheep to assess the model of the children’s axial pump «DON-3». The duration of the experiments in this series averaged 9 ± 5 days. The main indicators of hemodynamics, acid-base balance were within the norm. Conducted morphological and histological studies of the kidneys, liver and lungs did not reveal the presence of zones of ischemia and thromboembolism.Conclusion.The results of this series of experiments showed satisfactory results, suggesting further research on the development of prototypes of a pediatric pump for clinical practice. 


2019 ◽  
Vol 77 (2) ◽  
pp. 23-81
Author(s):  
Peter J. le B. Williams ◽  
Hugh W. Ducklow

The microbial loop as a leading concept in marine microbiology gained wide recognition in the 1980s, but it has roots extending back to the 1930s when microbiologists first began to take a more dynamic approach to investigating the roles of bacteria in ocean food webs and biogeochemical cycles. Here we present a history of the microbial loop concept with emphasis on the period starting in 1930, when marine bacteriologists in Russia and the West began to study explicitly the roles of marine bacteria in the sea. Selman Waksman at Woods Hole and Claude ZoBell at La Jolla relied on colony counts on agar plates as the basis of their work. We suggest that failure to accept direct microscopic evidence of high numbers of bacteria in seawater retarded conceptual development in the West well into the 1970s. Easterners pioneered direct count and radioisotopic techniques and created a dynamic marine microbiology integrating bacteria as important components of marine food webs by the 1960s. Yurii Sorokin and colleagues carried out extensive experimental studies of bacteria as food for marine grazers and provided data for Mikhail Vinogradov and his group to write the first numerical simulation models of ocean ecosystems incorporating microbial components. It had little impact on the Western modeling community, as other Russian work of the times. In spite of continuing technical shortcomings in the field, Lawrence Pomeroy constructed a new conceptual model, providing a synthesis pointing the way toward a modern view of marine microbial ecology that finally matured technically and conceptually in the West in the early 1980s.


2004 ◽  
Author(s):  
David I. Blekhman ◽  
Joseph C. Mollendorf ◽  
James D. Felske ◽  
John A. Lordi ◽  
Ashish M. Joshi

The Roots compressor has enjoyed a multitude of applications. Retuned to produce a high-temperature stream of gas, the Roots compressor can be a part of such applications as pyrolitic synthesis, chemical decomposition, optical fiber production and experimental studies. Presently, it appears that by using advanced materials, a prototype capable of withstanding temperatures up to 1500–2000 K could be built. A series of experiments was performed and various performance data were recorded at 2280 and 3430 rpm. The maximum steady state temperature achieved and the corresponding pressure ratio were 660 K and 3.9. Numerical modeling revealed a good correlation for pressure ratios up to 3. While the outlet pressure signature was accurately reproduced, the magnitude of the actual pressure fluctuation was somewhat in error. A more detailed physical model of gas dynamic processes could improve the agreement. The calculations were based on measurements of the internal leakage, need for modeling of which is emphasized.


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