Composition and Functional Groups Evaluation of Indonesian Grey Portland Cement as Material for Dental Application

2018 ◽  
Vol 782 ◽  
pp. 256-261 ◽  
Author(s):  
Indra Primathena ◽  
Denny Nurdin ◽  
Rahmi Alma Farah Adang ◽  
Arief Cahyanto

Tricalcium silicates cement known as Mineral Trioxide Aggregate (MTA) was one of the influential materials in endodontics. At recent, MTA in dental application play an essential role in endodontics treatment due to its potential to regenerate tertiary dentine, apexification, and seal perforated root. However, MTA for dental application is still expensive. Portland cement has similarities with the MTA, especially portland cement fabricated in Indonesia. The purpose of this study is to investigate the composition and functional groups of tricalcium silicate from portland cement that fabricated in Indonesia. The Indonesian grey portland cement powder/portland cement type I (SNI-15-7064-2014) was used as a sample and commercialized MTA from Tehnodent (Rootdent) was used as a control for comparison. Powder and control samples were evaluated using X-ray fluorescence spectrometry (XRF) for composition test and Fourier-transform infrared spectroscopy (FTIR) for functional group analyses. The XRF evaluation showed that the composition and concentration of Indonesian grey portland cement powder almost has similarity with commercial MTA. Moreover, the Indonesian grey portland cement powder has higher Calcium and Silicon ions compared to MTA. The FTIR analyses revealed that the calcium silicate groups were detected. In conclusion, the Indonesian grey portland cement powder has high similarity to MTA, therefore, it has a possibility to be used as tricalcium silicate cement for MTA substitution. Further study is awaited based on this initial finding found in this study.

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 417
Author(s):  
Indra Primathena ◽  
Denny Nurdin ◽  
Hendra Hermawan ◽  
Arief Cahyanto

Mineral trioxide aggregate (MTA) is an ideal yet costly endodontic sealer material. Tricalcium silicate-white Portland cement (TS-WPC) seems to have similar characteristics to those of MTA. This work aims to characterize a modified TS-WPC and evaluate its antibacterial properties as a potential endodontic sealer material. The modified TS-WPC was synthesized from a 4:1 mixture of sterilized Indocement TS-WPC and bismuth trioxide using a simple solution method with 99.9% isopropanol. The mixture was stirred until it was homogenous, centrifuged, and dried. The material was then characterized using infrared spectroscopy, X-ray diffraction, and electron microscopy and subjected to antibacterial evaluation against Enterococcus faecalis using a Mueller–Hinton agar inhibition test. The results showed that the material was characterized by main functional groups of hydroxyls, silicate, bismuth trioxide, and tricalcium silicate, like those of a commercial MTA-based sealer, both tested after hydration. Modified TS-WPC before hydration showed similar powder morphology and size to the commercial one, indicating the ease of manipulation. Both materials exhibited antibacterial activity due to calcium dihydroxide’s ability to absorb carbon dioxide, which is essential for the anaerobic E. faecalis, with minimum inhibitory effect and bactericidal concentrations of 12,500 ppm and 25,000 ppm, respectively. The modified TS-WPC has the potential to become a cost-effective alternative endodontic sealer material.


2019 ◽  
Vol 829 ◽  
pp. 34-39
Author(s):  
Denny Nurdin ◽  
Indra Primathena ◽  
Rahmi Alma Farah ◽  
Arief Cahyanto

Pulp capping has been suggested as one treatment of choice after pulp exposure. Calcium hydroxide [Ca (OH)2] recognized as gold standard of direct pulp capping matter for some decades. Throughout the time, a new cement known as mineral trioxide aggregate (MTA) has developed into a prominent alternative. A recent study found that matter as the most effective pulp capping material. Despite the fact, MTA is an expensive material. Several studies in different country show that portland cement has highly similarity chemical composition with MTA. The purpose of this study is to evaluate the chemical composition of white portland cement that fabricated in Indonesia compared to MTA. White portland cement fabricated in Indonesia was used as a sample in this study and commercial MTA as a control. Samples and control were assessed using X-ray fluorescence spectrometry (XRF) to figure out chemical composition and concentration. Investigating the wavelength of the functional group using Fourier Transform Infrared Spectroscopy (FTIR). The results show that composition, concentration, and functional group either Indonesian white portland cement and MTA has highly similar. Hence, it has a chance to use Indonesian white portland cement for dental pulp capping material as MTA substitution.


e-Polymers ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 61-68
Author(s):  
Dong Zhang ◽  
Jian Guang Wei ◽  
Run Nan Zhou

AbstractActive-polymer attracted increasing interest as an enhancing oil recovery technology in oilfield development owing to the characteristics of polymer and surfactant. Different types of active functional groups, which grafted on the polymer branched chain, have different effects on the oil displacement performance of the active-polymers. In this article, the determination of molecular size and viscosity of active-polymers were characterized by Scatterer and Rheometer to detect the expanded swept volume ability. And the Leica microscope was used to evaluate the emulsifying property of the active-polymers, which confirmed the oil sweep efficiency. Results show that the Type I active-polymer have a greater molecular size and stronger viscosity, which is a profile control system for expanding the swept volume. The emulsification performance of Type III active-polymer is more stable, which is suitable for improving the oil cleaning efficiency. The results obtained in this paper reveal the application prospect of the active-polymer to enhance oil recovery in the development of oilfields.


npj Vaccines ◽  
2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Awadalkareem Adam ◽  
Camila R. Fontes-Garfias ◽  
Vanessa V. Sarathy ◽  
Yang Liu ◽  
Huanle Luo ◽  
...  

AbstractAlthough live attenuated vaccines (LAVs) have been effective in the control of flavivirus infections, to date they have been excluded from Zika virus (ZIKV) vaccine trials due to safety concerns. We have previously reported two ZIKV mutants, each of which has a single substitution in either envelope (E) glycosylation or nonstructural (NS) 4B P36 and displays a modest reduction in mouse neurovirulence and neuroinvasiveness, respectively. Here, we generated a ZIKV mutant, ZE4B-36, which combines mutations in both E glycosylation and NS4B P36. The ZE4B-36 mutant is stable and attenuated in viral replication. Next-generation sequence analysis showed that the attenuating mutations in the E and NS4B proteins are retained during serial cell culture passages. The mutant exhibits a significant reduction in neuroinvasiveness and neurovirulence and low infectivity in mosquitoes. It induces robust ZIKV-specific memory B cell, antibody, and T cell-mediated immune responses in type I interferon receptor (IFNR) deficient mice. ZIKV-specific T cell immunity remains strong months post-vaccination in wild-type C57BL/6 (B6) mice. Vaccination with ZE4B-36 protects mice from ZIKV-induced diseases and vertical transmission. Our results suggest that combination mutations in E glycosylation and NS4B P36 contribute to a candidate LAV with significantly increased safety but retain strong immunogenicity for prevention and control of ZIKV infection.


Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Masayuki Shimano ◽  
Rei Shibata ◽  
Yukiomi Tsuji ◽  
Noriyuki Ouchi ◽  
Yasuya Inden ◽  
...  

The occurrence and development of atrial fibrillation (AF) are associated with changes in electrical properties and cardiac structure, known as electrical and structural atrial remodeling. AF characterized by atrial remodeling also occurs with obesity-related conditions. Adiponectin, an adipose tissue-derived hormone, exerts beneficial effects on the heart in various pathological conditions. These observations led us to speculate that adiponectin levels affect the development and prevalence of AF. Here, we investigated a potential association between circulating adiponectin levels and atrial remodeling in patients with AF. We measured plasma adiponectin levels, serum carboxy-terminal telopeptide of collagen type I (CITP) levels, as a collagen type I degradation marker, and serum type III procollagen-N-peptide (PIIINP) levels, as a collagen type III synthesis marker in consecutive 414 patients; 225 paroxysmal AF, 81 persistent AF and 108 paroxysmal supra-ventricular tachycardia without AF history (control) patients, who admitted for scheduled radiofrequency catheter ablation. Plasma adiponectin levels were significantly higher in patients with persistent AF compared to paroxysmal AF and control patients (p<0.05). Serum CITP levels, but not serum PIIINP levels, were also higher in patients with persistent AF compared to paroxysmal AF and control patients (p<0.05). In addition, a positive correlation was observed between adiponectin levels and CITP levels (r=0.39, p<0.005) or the P wave duration (r=−0.31, p<0.05) in patients with persistent AF. High plasma adiponectin levels are associated with the presence of persistent AF, which is accompanied by increased CITP levels. Hyperadiponectinemia might also attenuate atrial conduction disturbance. Thus, measurement of plasma adiponectin could be useful for assessment of AF.


2021 ◽  
Vol Special issue (1) ◽  
pp. 51-56
Author(s):  
Nigora Djuraeva ◽  

The article presents the results of using a material based on the mineral trioxide unit “Bio-Dent”for the indirect coating of the pulp. It was found that there were no complaints from the use of domestic Portland cement both in the near term (98.8%) and inthe long term after treatment in comparison with materials based on calcium hydroxide (72.5%). Stabilization of the pulp electroexcitability indicators at the level of 10 mkA was noted with the use of the material based on MTA “Bio-Dent”as a medical liner for indirect pulp covering.Keywords: dental pulp,indirect pulp coating, calcium hydroxide, mineral trioxide aggregate, pulp electroexcitability.


2010 ◽  
Vol 93 (1) ◽  
pp. 279-287 ◽  
Author(s):  
Linghong Zhang ◽  
Lionel J. J. Catalan ◽  
Raymond J. Balec ◽  
Andrew C. Larsen ◽  
Hassan Haji Esmaeili ◽  
...  

1977 ◽  
Vol 2 (3) ◽  
pp. 187-206 ◽  
Author(s):  
Charles G. Martin ◽  
Paul A. Games

This paper presents an exposition and an empirical comparison of two potentially useful tests for homogeneity of variance. Control of Type I error rate, P(EI), and power are investigated for three forms of the Box test and for two forms of the jackknife test with equal and unequal n's under conditions of normality and nonnormality. The Box test is shown to be robust to violations of the assumption of normality. The jackknife test is shown not to be robust. When n's are unequal, the problem of heterogeneous within-cell variances of the transformed values and unequal n's affects the jackknife and Box tests. Previously reported suggestions for selecting subsample sizes for the Box test are shown to be inappropriate, producing an inflated P(EI). Two procedures which alleviate this problem are presented for the Box test. Use of the jack-knife test with a reduced alpha is shown to provide power and control of P(EI) at approximately the same level as the Box test. Recommendations for the use of these techniques and computational examples of each are provided.


2020 ◽  
Author(s):  
Tyler G. Ekins ◽  
Vivek Mahadevan ◽  
Yajun Zhang ◽  
James A. D’Amour ◽  
Timothy Petros ◽  
...  

ABSTRACTType I lissencephaly is a neuronal migration disorder caused by haploinsuffiency of the LIS1 gene and is characterized in humans by agyria, mislamination of brain structures, developmental delays, and epilepsy. Here, we investigate the impact of LIS1 mutation on the cellular migration, morphophysiology, microcircuitry and genomics of mouse hippocampal CA1 parvalbumin-containing inhibitory interneurons (PV+INTs). We find that WT PV+INTs consist of two physiological subtypes (80% fast-spiking (FS), 20% non-fast-spiking (NFS)) and four morphological subtypes (basket, axo-axonic, bistratified, radiatum-targeting). We also discover that cell-autonomous mutations within interneurons disrupts morphological development of PV+INTs and results in the emergence of a non-canonical “intermediate spiking (IS)” subset of PV+INTs. In the GlobalLis mutant, IS/NFS cells become the dominant PV+INT subtypes (56%) and the percentage of FS cells shrinks to 44%. We also find that IS/NFS cells are prone to entering depolarizing block, causing them to temporarily lose the ability to initiate action potentials and control network excitation, potentially promoting seizures. Finally, single-cell nuclear RNAsequencing of PV+INTs revealed several misregulated genes related to morphogenesis, cellular excitability, and synapse formation.


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