Scoring Analysis of Design, Verification and Optimization of High Intensity Positron Source (HIPOS)

2012 ◽  
Vol 733 ◽  
pp. 297-305
Author(s):  
Andrej Zeman ◽  
K. Tuček ◽  
G. Daquino ◽  
L. Debarberis ◽  
A. Hogenbirk
Keyword(s):  
Neutron Beam ◽  
High Intensity ◽  
Reactor Core ◽  
Beam Line ◽  
Research Centre ◽  
Design Parameters ◽  
Exploratory Research ◽  
Positron Source ◽  
Main Concept ◽  
Joint Research

As part of an exploratory research project at the Institute for Energy (Joint Research Centre of the European Commission), a feasibility assessment was performed for the design and construction of a high-intensity positron facility (HIPOS) in a neutron beam tube, HB9, at the High Flux Reactor (HFR) in Petten. The full model of reactor core, reflector and reactor instrumentation at the neutron beam line HB9 were modeled and full neutronic and photonic calculations were carried out by MCNP4C3. The source file was generated in two formats: SDEF and WESSA. Consequently, two different codes were used for scoring analysis for the optimization of the concept and geometry of positron generator. The main concept including key design parameters have been evaluated independently by two computer codes, in particular MCNP-X and GEANT4. The parametric design analysis including the optimization of positron generator at the pre-selected neutron beam line is reported in this paper. The detailed assessment of the critical design parameters, specifically from technological point of view is summarised. The results of independent analysis confirmed that the best approach is to combine two concepts of positron generation, which are based on the exploiting of neutron and gamma radiation. The results verified that the proposed concept can reach the defined threshold of the positron yield and the positron beam can reach an intensity of 1013e+/sec (un-moderated). The details of completed work are reported in this paper.

scholarly journals Sustainability Assessment of Second Use Applications of Automotive Batteries: Ageing of Li-Ion Battery Cells in Automotive and Grid-Scale Applications

2018 ◽  
Vol 9 (2) ◽  
pp. 24 ◽  
Author(s):  
Andreas Podias ◽  
Andreas Pfrang ◽  
Franco Di Persio ◽  
Akos Kriston ◽  
Silvia Bobba ◽  
...  
Keyword(s):  
Second Life ◽  
Sustainability Assessment ◽  
Lithium Ion ◽  
Research Centre ◽  
Impedance Change ◽  
Exploratory Research ◽  
Joint Research ◽  
Duty Cycles ◽  
Automotive Batteries ◽  
Second Use

The Sustainability Assessment of Second Life Applications of Automotive Batteries (SASLAB) exploratory research project of the European Commission’s Joint Research Centre (JRC) aims at developing and applying a methodology to analyse the sustainability of deploying electrified vehicles (xEV) batteries in second use applications. A mapping of industrial demonstration and publicly-funded research projects in the area is presented, followed by an experimental assessment of the capacity and impedance change of lithium-ion cells during calendar and cycle ageing. Fresh cells and cells aged in the laboratory, as well as under real-world driving conditions, have been characterised to understand their application-specific remaining lifetime, beyond the 70% to 80% end-of-first-use criterion. For this purpose, pre-aged cells were examined under duty-cycles that resemble those of second use grid-scale applications.

scholarly journals Profiling of Sub-Lethal in Vitro Effects of Multi-Walled Carbon Nanotubes Reveals Changes in Chemokines and Chemokine Receptors

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 883 ◽  
Author(s):  
Sandeep Keshavan ◽  
Fernando Torres Andón ◽  
Audrey Gallud ◽  
Wei Chen ◽  
Knut Reinert ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Chemokine Receptors ◽  
Research Centre ◽  
Target Cells ◽  
Joint Research ◽  
Chemokine Signaling ◽  
Multi Walled Carbon Nanotubes ◽  
Downstream Analysis ◽  
Walled Carbon Nanotubes

Engineered nanomaterials are potentially very useful for a variety of applications, but studies are needed to ascertain whether these materials pose a risk to human health. Here, we studied three benchmark nanomaterials (Ag nanoparticles, TiO2 nanoparticles, and multi-walled carbon nanotubes, MWCNTs) procured from the nanomaterial repository at the Joint Research Centre of the European Commission. Having established a sub-lethal concentration of these materials using two human cell lines representative of the immune system and the lungs, respectively, we performed RNA sequencing of the macrophage-like cell line after exposure for 6, 12, and 24 h. Downstream analysis of the transcriptomics data revealed significant effects on chemokine signaling pathways. CCR2 was identified as the most significantly upregulated gene in MWCNT-exposed cells. Using multiplex assays to evaluate cytokine and chemokine secretion, we could show significant effects of MWCNTs on several chemokines, including CCL2, a ligand of CCR2. The results demonstrate the importance of evaluating sub-lethal concentrations of nanomaterials in relevant target cells.

Silver nanoparticles induce cytotoxicity, but not cell transformation or genotoxicity on Balb3T3 mouse fibroblasts

2013 ◽  
Vol 14 (1-2) ◽  
pp. 49-60 ◽  
Author(s):  
Francesca Broggi ◽  
Jessica Ponti ◽  
Guido Giudetti ◽  
Fabio Franchini ◽  
Vicki Stone ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Cell Transformation ◽  
Micronucleus Test ◽  
Chemical Properties ◽  
Neoplastic Transformation ◽  
Research Centre ◽  
Ag Nps ◽  
Joint Research ◽  
Ic50 Values ◽  
Average Size

AbstractSilver nanoparticles (Ag NPs) are one of the most common nanomaterials present in nanotechnology-based products. Here, the physical chemical properties of Ag NPs suspensions of 44 nm, 84 nm and 100 nm sizes synthesized in our laboratory were characterized. The NM-300 material (average size of 17 nm), supplied by the Joint Research Centre Nanomaterials Repository was also included in the present study. The Ag NPs potential cytotoxicity was tested on the Balb3T3 cell line by the Colony Forming Efficiency assay, while their potential morphological neoplastic transformation and genotoxicity were tested by the Cell Transformation Assay and the micronucleus test, respectively. After 24 h of exposure, NM-300 showed cytotoxicity with an IC50 of 8 µM (corresponding to 0.88 µg/mL) while for the other nanomaterials tested, values of IC50 were higher than 10 µM (1.10 µg/mL). After 72 h of exposure, Ag NPs showed size-dependent cytotoxic effect with IC50 values of 1.5 µM (1.16 µg/mL) for NM-300, 1.7 µM (1.19 µg/mL) for Ag 44 nm, 1.9 µM (0.21 µg/mL) for Ag 84 nm and 3.2 µM (0.35 µg/mL) for Ag 100 nm. None of the Ag NPs tested was able to induce either morphological neoplastic transformation or micronuclei formation.

scholarly journals Reactor Core Conceptual Design for a Scalable Heating Experimental Reactor, LUTHER

2021 ◽  
Vol 2 (2) ◽  
pp. 207-214
Author(s):  
Thinh Truong ◽  
Heikki Suikkanen ◽  
Juhani Hyvärinen
Keyword(s):  
Low Temperature ◽  
Conceptual Design ◽  
Nuclear Power ◽  
Water Pressure ◽  
Reactor Core ◽  
Electricity Production ◽  
Design Parameters ◽  
Experimental Reactor ◽  
Fuel Assemblies ◽  
Enriched Uranium

In this paper, the conceptual design and a preliminary study of the LUT Heating Experimental Reactor (LUTHER) for 2 MWth power are presented. Additionally, commercially sized designs for 24 MWth and 120 MWth powers are briefly discussed. LUTHER is a scalable light-water pressure-channel reactor designed to operate at low temperature, low pressure, and low core power density. The LUTHER core utilizes low enriched uranium (LEU) to produce low-temperature output, targeting the district heating demand in Finland. Nuclear power needs to contribute to the decarbonizing of the heating and cooling sector, which is a much more significant greenhouse gas emitter than electricity production in the Nordic countries. The main principle in the development of LUTHER is to simplify the core design and safety systems, which, along with using commercially available reactor components, would lead to lower fabrication costs and enhanced safety. LUTHER also features a unique design with movable individual fuel assembly for reactivity control and burnup compensation. Two-dimensional (2D) and three-dimensional (3D) fuel assemblies and reactor cores are modeled with the Serpent Monte Carlo reactor physics code. Different reactor design parameters and safety configurations are explored and assessed. The preliminary results show an optimal basic core design, a good neutronic performance, and the feasibility of controlling reactivity by moving fuel assemblies.

PLACE AND ROLE OF COMPETENT INFORMATION IN THE MANAGEMENT OF SCIENTIFIC AND TECHNOLOGICAL DEVELOPMENT

Naukovedenie ◽  
2021 ◽  
pp. 123-138
Author(s):  
Sergei Pyastolov ◽  
Keyword(s):  
European Union ◽  
Technological Development ◽  
Research Centre ◽  
Joint Research ◽  
Joint Research Centre ◽  
Science Activity ◽  
Scientific Organizations ◽  
Special Space ◽  
Scientific And Technological Development

VUCA world (Volatility, Uncertainty, Complexity, Ambiguity), according to experts of JRC (European Commission's Joint Research Centre), is now a special space that corrupts the integrity of science activity, limits thinking and vision of the situation by politicians. In fact, under such conditions, the only reliable resource for scientific organizations is a commercialization, and the payback is a condition of activity. These factors already pose a threat to global security. The mission orientation proposed by European Union experts is still seen as a rather weak alternative.

scholarly journals Analysing inter-relationships among water, governance, human development variables in developing countries

2012 ◽  
Vol 16 (10) ◽  
pp. 3791-3816 ◽  
Author(s):  
C. Dondeynaz ◽  
C. Carmona Moreno ◽  
J. J. Céspedes Lorente
Keyword(s):  
Developing Countries ◽  
Water Resources ◽  
Water Supply ◽  
Human Development ◽  
Environmental Concern ◽  
Water Governance ◽  
Development Aid ◽  
Research Centre ◽  
Joint Research ◽  
Discussion Section

Abstract. The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC) of the European Commission (EC) has developed a new database (WatSan4Dev database) containing 42 indicators (called variables in this paper) from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality, and finally, the analysis to verify the database coherence is presented. Based on 25 relevant variables, the relationships between variables are described and organised into five factors (HDP – Human Development against Poverty, AP – Human Activity Pressure on water resources, WR – Water Resources, ODA – Official Development Aid, CEC – Country Environmental Concern). Linear regression methods are used to identify key variables having influence on water supply and sanitation. First analysis indicates that the informal urbanisation development is an important factor negatively influencing the percentage of the population having access to WSS. Health, and in particular children's health, benefits from the improvement of WSS. Irrigation is also enhancing Water Supply service thanks to multi-purpose infrastructure. Five country profiles are also created to deeper understand and synthetize the amount of information gathered. This new classification of countries is useful in identifying countries with a less advanced position and weaknesses to be tackled. The relevance of indicators gathered to represent environmental and water resources state is questioned in the discussion section. The paper concludes with the necessity to increase the reliability of current indicators and calls for further research on specific indicators, in particular on water quality at national scale, in order to better include environmental state in analysis to WSS.

Stability of neutron beam monitor for High Intensity Total Diffractometer at J-PARC

2012 ◽  
Vol 672 ◽  
pp. 75-81 ◽  
Author(s):  
Hidetoshi Ohshita ◽  
Toshiya Otomo ◽  
Shoji Uno ◽  
Kazutaka Ikeda ◽  
Tomohisa Uchida ◽  
...  
Keyword(s):  
Neutron Beam ◽  
High Intensity ◽  
Beam Monitor

scholarly journals Preface

2006 ◽  
Vol 78 (1) ◽  
pp. viii
Author(s):  
Michael Bickel
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Trace Element Analysis ◽  
The Body ◽  
Research Centre ◽  
Food Contaminants ◽  
Joint Research ◽  
Element Analysis ◽  
Fortified Food ◽  
Animal Metabolism

Trace elements may have different functions in human and animal metabolism: some are toxic (e.g., Hg), others are essential to maintain good health (e.g., Ca), or they can be essential but also toxic, depending on the concentration in the body or in parts thereof (e.g., Se).The importance of various aspects of trace elements in relation to food is steadily increasing in the perception of the consumer and the respective authorities: food contaminants, essential and toxic elements, bioavailability and speciation, nutritional value and fortified food, reliable measurement of contents, etc. In addition, through the many minor and major food-related incidents during recent years the consumer is becoming more concerned about the quality and safety of food. As a result, research and development efforts in this area have also been increased and/or been redirected.TEF-2 was organized in Brussels 7-8 October 2004 by the Institute of Reference Materials and Measurements of the Joint Research Centre of the European Commission, with the support of the Department of Food Analysis, Institute of Agricultural and Food Biotechnology of the University of Warzaw, Poland and the Centre National de la Recherche Scientifique, France. It was carried through under the auspices of IUPAC.The objectives laid down for the symposium were- presenting state-of-the-art analytical methods for the enforcement of legal limits of trace elements in food;- disseminating new ideas and findings within the scientific community;- providing a forum for the exchange of new knowledge and experience between R&D, authorities, and industry; and- bringing together experts in the field with newcomers.TEF-2 was attended by 93 participants from 60 different institutions in 23 countries. It consisted of 26 lectures and 56 posters, structured according to the following four main topics:- trace elements in the food chain (from the environment to shelf product) including the effects of processing and of legislation- trace element bioavailability-toxicological and nutritional aspects- fortified food and supplementation legislation, manufacturing and labeling, standards- advances in trace element analysis in food matricesIt was emphasized that the field of trace elements in food is a lively research area, which generates interest and involvement from researchers, authorities, and industry, of course triggered and nurtured by the equally high interest of the consumer. A selection of the invited contributions to TEF-2 is presented in the subsequent seven papers in this issue.The importance of scientific exchange in this field was, again, recognized during TEF-2. Therefore, the continuation of this series of conferences was discussed, and the venue for the subsequent TEF-3 was decided. It will be organized by R. Lobinski of CNRS in Pau, France, at the beginning of October 2008.Michael BickelConference Editor

scholarly journals JRC activities in nuclear safety

2009 ◽  
Vol 24 (1) ◽  
pp. 18-28 ◽  
Author(s):  
Giustino Manna ◽  
Luigi Debarberis ◽  
Andrea Bucalossi ◽  
Roberto May ◽  
Michel Bieth ◽  
...  
Keyword(s):  
Nuclear Energy ◽  
Scientific Work ◽  
Nuclear Safety ◽  
Research Centre ◽  
Joint Research ◽  
Joint Research Centre ◽  
The Public ◽  
Base Load ◽  
Management Issues ◽  
The Eu

Nuclear energy is today the largest single source of carbon free and base-load electricity in Europe. While highlighting its important role in the overall energy mix, it is necessary to address sustainability, safety, and security concerns, in particular nuclear safety and nuclear waste management issues, which influence the public acceptance of nuclear energy. The present paper describes the Joint Research Centre activities in support to the EU nuclear safety policy. It describes the Joint Research Centre role in the EU institutional context, identifies the various customers to which the Joint Research Centre delivers its services, and provides some results of the Joint Research Centre scientific work inherent to nuclear safety.

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