Effects of quail (Coturnix japonica) egg diet on both the blood sugar and the lipid profile of alloxan induced diabetic albino rats

Cold and immobilization stressors can generate oxidative stress as well as skeletal muscle fatigue. Free radicals cause oxidative degradation of lipids, proteins, nucleic acids, and carbohydrates molecules, thereby compromising cell integrity and function. Quail egg had been described as being very functional biochemically, due to the essential biomolecules it contains in very regulated quantity. This study was aimed for evaluating the dietary effect of the egg on lipid profile parameters on selected tissues. The antilipidemic properties of the egg yolk and albumen and poultry (layers) feed were determined in selected tissues in male albino rats assaulted with cold immobilization stress induced on them at 4°C for 2 hours, while diazepam was used as standard antistress drug. Antilipidemic activities were evaluated by lipid profile modulation (HDL, LDL, TRIG., and T-CHOL.). Quantitative and qualitative analyses of fatty acids profile of the yolk hexane-extract were determined by Gas Chromatography and Mass Spectrophotometry (GC-MS). The ameliorative impacts of diazepam (2.5 and 5.0 mg/mL/kg BW), yolk (5 and 10 mL/kg BW), albumen (5 and 10 mL/kg BW), and the feed (5–10 mg/kg BW) were competitively (p<0.05) specific for each of the tissues. The result of the study suggested yolk and albumen of quail egg and poultry feed as antistress agents as well as lipid modulators.

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Effect of Oral Intake of African Locust Bean on Fasting Blood Sugar and Lipid Profile of Albino Rats

Asian Journal of Research in Biochemistry ◽

10.9734/ajrb/2019/v4i430073 ◽

2019 ◽

pp. 1-9

Author(s):

Augustine I. Airaodion ◽

Edith O. Airaodion ◽

Emmanuel O. Ogbuagu ◽

Uloaku Ogbuagu ◽

Etinosa U. Osemwowa

Keyword(s):

Body Weight ◽

Lipid Profile ◽

Blood Sugar ◽

Saline Solution ◽

Fasting Blood Sugar ◽

Control Group ◽

Albino Rats ◽

Locust Bean ◽

African Locust Bean ◽

Ibadan Nigeria

Background: African locust bean is a condiment believed to be for the people of low class. Its health importance has not been fully known especially to the so-called high class. Aim: This study is aimed at investigating the effect of African locust bean on fasting blood sugar and lipid profile of albino rats. Methods: African locust bean (ALB) was purchased from a local market at Orita-Challenge area of Ibadan, Nigeria. They were sun dried and milled into powder using an electronic blender. The powder was extracted with n-hexane (40–60°C) in a soxlet extractor for 18 hours. The defatted, dried marc was repacked and then extracted with methanol. The dried marc was extracted with methanol in the soxlet apparatus for 10 hours. The methanol solution was subsequently concentrated in a rotatory evaporator at 40°C. Ten adult male albino rats with body weight between 100 and 120 g were purchased from the Animal Holding Unit of the Department of Physiology, University of Ibadan, Nigeria. They were allowed 7 days acclimatization period and were divided randomly into 2 groups of five rats each. Animals in group 1 were administered normal saline solution while those in group 2 were administered extract of African locust bean. The animals were exposed to the African Locust Bean and saline solution at a dose of 3 ml per 100 g body weight 12 hourly via oral route of administration. After fourteen days of administration, the animals were fasted overnight and anaesthetized using diethyl ether. Blood samples were collected by cardiac puncture. Results: ALB was observed to significantly lower fasting blood sugar, total cholesterol and triglyceride but increased HDL-cholesterol significantly when compared to those of the control group at p<0.05. LDL-cholesterol was not significantly different when animals treated with ALB were compared with those of the control group. Conclusion: Increased blood sugar and hyperlipidemia has been implicated in diabetes. Cholesterolgenesis is a major onset of atherosclerosis and subsequent cardiovascular diseases. Therefore, ALB can serve as prophylaxis and remedies for several diseases caused by hyperglycemia and hyperlipidemia such as diabetes and coronary heart disease.

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The effect of Ramadan fasting on body weight, fasting blood sugar and lipid profile of normal male healthy non obese male medical college students in Tikrit city.

10.36295/asro.2020.2325 ◽

2020 ◽

Vol 23 (02) ◽

pp. 29-35

Author(s):

Abdulrahman Jihad Mansoor

Keyword(s):

College Students ◽

Body Weight ◽

Lipid Profile ◽

Blood Sugar ◽

Fasting Blood Sugar ◽

Normal Male ◽

Ramadan Fasting ◽

Medical College ◽

Obese Male

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Influence of irisin on diet-induced metabolic syndrome in experimental rat model

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2020-0030 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Dalia Medhat ◽

Mona A. El-Bana ◽

Sherien M. El-Daly ◽

Magdi N. Ashour ◽

Tahany R. Elias ◽

...

Keyword(s):

Skeletal Muscle ◽

Lipid Profile ◽

Histopathological Examination ◽

Retinol Binding Protein ◽

Albino Rats ◽

Standard Diet ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Alcoholic Fatty Liver ◽

Kidney Functions

Abstract Objective To evaluate the influence of irisin on the experimental paradigm of non-alcoholic fatty liver (NAFL) as a part of MetS cluster. Methods Forty male albino rats were divided into four groups; normal control, standard diet + irisin, high carbohydrate and fat diet (HCHF), and HCHF + irisin. After the experimental period, levels of fasting blood sugar (FBS), insulin, lipid profile, kidney functions, salusin-alpha (Sal-α), adropin, and retinol-binding protein-4 (RBP-4) were evaluated. Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1α) expression in skeletal muscle was evaluated by quantitative real-time PCR. Aorta, liver, pancreas, and skeletal muscle tissue samples were prepared for histopathological examination. Results Rats administrated HCHF showed elevated levels of FBS, lipid profile, kidney functions, RBP-4, and downregulation of PGC-1α expression along with a decline in levels of insulin, Sal-α, and adropin while administration of irisin significantly attenuated these levels. Conclusions Irisin as based therapy could emerge as a new line of treatment against MetS and its related diseases.

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