scholarly journals Metabolic syndrome and cognitive decline: the role of physical activity

2013 ◽  
Vol 86 (1) ◽  
Author(s):  
M. Rinaldi ◽  
G. Graffi ◽  
E. Rabino Massa
Keyword(s):  
Physical Activity ◽  
Metabolic Syndrome ◽  
Cognitive Decline ◽  
Central Obesity ◽  
Mini Mental State Examination ◽  
Metabolic Diseases ◽  
Sedentary Lifestyle ◽  
Activity Level ◽  
State Examination

Metabolic Syndrome (MetS) is a cluster of conditions, each of which represents a risk factor for cardiovascular disease: central obesity, hyperglycemia, dyslipidemia and hypertension. Any of these conditions and MetS itself have been associated to Alzheimer's Disease and Vascular Dementia. In recent years there is a growing evidence for the role of physical activity in preventing metabolic diseases and cognitive decline. In our research we assessed the prevalence of MetS in a sample of 154 elderly people. Furthermore, we evaluated cognition (with Mini Mental State Examination, MMSE)  and the physical activity level in every patient. We found a significant association between MetS, borderline cognitive impairment and sedentary lifestyle.

scholarly journals HUBUNGAN STATUS PERKAWINAN, APOE ε4, DAN JENIS AKTIVITAS FISIK TERHADAP PENURUNAN KOGNITIF PADA LANSIA PEREMPUAN

2020 ◽  
Vol 36 (2) ◽  
Author(s):  
Nicholas Andrian Singgih ◽  
Yuda Turana ◽  
Yvonne Suzy Handajani ◽  
Nelly Tina Widjaja ◽  
Linda Suryakusuma
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Marital Status ◽  
Mini Mental State Examination ◽  
Elderly Women ◽  
Active Aging ◽  
Vascular Risk ◽  
Apoe Ε4 ◽  
State Examination

      RELATIONSHIP OF MARITAL STATUS, APOE ε4, AND TYPES OF PHYSICAL ACTIVITIES ON COGNITIVE DECLINE IN ELDERLY WOMENABSTRACTIntroduction: The number of elderly population in Indonesia continues to increase every year, especially women. Elderly women are at higher risk of experiencing decreased cognitive function.Aims: To determine the relationship between the characteristics  of the subject, vascular risk factors, APOE ε4 genotype, and the type of physical activity with the decline of cognitive function in elderly women.Methods: A cognitive cohort study of 114 elderly women who had been observed for a mean of ±2.5 years, as part of the Active Aging study at Atma Jaya Catholic University. The independent variables of this study included were age, education, marital status, vascular risk factors (hypertension, diabetes, dyslipidemia, and BMI), APOE ε4, and types of physical activity. Cognitive function is measured using Mini Mental State Examination (MMSE).Results: There were 114 subjects with mean age was 71.22±7.297 and 33.3% experienced a decline in cognitive function. There were 114 subjects with mean age was 71.22±7.297 and 33.3% experienced a decline in cognitive function. Age, marital status (single), and type of physical activity (cooking) have a significant relationship with Relative Risk (RR) of 4,45; 0,12; and 0,334.Discussions: Factors related to cognitive decline in elderly women were age. Marital status (single) and  cooking activities  were  protective factors.Keywords: APOE, cognitive decline, elderly, marital status, physical activityABSTRAKPendahuluan: Angka populasi lansia di Indonesia setiap tahunnya terus meningkat, terutama perempuan. Lansia perempuan berisiko lebih tinggi mengalami penurunan fungsi kognitif.Tujuan: Mengetahui hubungan antara karakteristik subjek, faktor risiko vaskuler, genotip APOE ε4, dan jenis aktivitas fisik terhadap penurunan fungsi kognitif pada lansia perempuan.Metode: Penelitian kohort terhadap 114 lansia perempuan >60 tahun yang diikuti fungsi kognitifnya selama rerata ±2,5 tahun, sebagai bagian dari penelitian Active Aging di Universitas Katolik Atma Jaya. Variabel bebas penelitian ini meliputi usia, pendidikan, status perkawinan, faktor risiko vaskuler (hipertensi, diabetes, dislipidemia, dan IMT), APOE ε4, dan jenis aktivitas fisik. Fungsi kognitif diukur menggunakan Mini Mental State Examination (MMSE).Hasil: Didapatkan 114 subjek dengan rerata usia 71,2±7,3 dan 33,3% mengalami penurunan fungsi kognitif. Analisis multivariat menunjukkan usia, status perkawinan (single) , dan jenis aktivitas fisik (memasak) memiliki hubungan bermakna dengan risiko relatif (RR) masing-masing 4,46; 0,12; dan 0,334.Diskusi: Faktor risiko gangguan fungsi kognitif pada lansia perempuan adalah usia. Status perkawinan (single) dan aktivitas memasak merupakan faktor protektif.Kata kunci: Status perkawinan, APOE, aktivitas fisik, penurunan kognitif, lanjut usia  

scholarly journals Role of cholesterol in cognitive function in the elderly

2021 ◽  
Vol 8 (2) ◽  
pp. 56-59
Author(s):  
V K Deshpande ◽  
Vishwin Doda
Keyword(s):  
Cognitive Function ◽  
Cognitive Decline ◽  
Mental State ◽  
Mini Mental State Examination ◽  
Blood Cholesterol ◽  
Elderly Subjects ◽  
Blood Concentrations ◽  
Cholesterol Levels ◽  
State Examination

The role of cholesterol in Cognitive Decline is less known as compared to other pathologies linked with dyslipidaemia. However, Cholesterol is well-known to have multiple functions in normal functioning of the brain and the aging process. This study therefore aimed at finding a co-relation, if any, between Cholesterol and age-related cognitive decline.To assess Cognitive Function of subjects and compare it with respective blood cholesterol levels. The study included 50 elderly subjects from Maharashtra (females: 12%) assessed using Marathi version of Mini Mental State Examination (MMSE) and their cholesterol blood concentrations obtained using a Lipid Profile investigation. Cholesterol levels and cognitive function was then co-related using statistical analysis.The subjects with a higher Total Cholesterol & LDL Cholesterol had slightly less scores on the Mini Mental State Examination (MMSE) Test. However, the difference was found to be significant.Based on the results obtained, no relevant co-relation could be found between Blood Cholesterol Levels and Cognitive Function

The Role of Physical Activity and Diet on Overall and Central Obesity Incidence

2011 ◽  
Vol 8 (6) ◽  
pp. 811-819 ◽  
Author(s):  
Miguel Camões ◽  
Andreia Oliveira ◽  
Carla Lopes
Keyword(s):  
Physical Activity ◽  
Central Obesity ◽  
Leisure Time ◽  
Resting Metabolic Rate ◽  
Incidence Rates ◽  
Activity Level ◽  
Relative Risks ◽  
Different Types ◽  
Dietary Score

Objective:Evaluate the role of different types of physical activity (PA) and diet on overall and central obesity incidence.Methods:A cohort study with 1621 adults was conducted in an urban Portuguese population. Anthropometrics were objectively obtained during 1999−2003 and 2005−2008. Overall, obesity was defined by a body mass index (BMI) ≥ 30.0 kg/m2 and central obesity by a waist circumference (WC) > 88.0 cm in women and >102.0 cm in men. Usual PA and dietary intake were assessed using validated questionnaires. Analyses of obesity incidence were conducted through different types of PA and a “healthy” dietary score.Results:Significant inverse associations were found between leisure-time PA and obesity incidence, namely among subjects classified into the last tertile of energy expenditure, who had approximately a 40% lower risk of developing the disease. Despite higher energy intakes, individuals with a high Physical Activity Level (PAL > 1.60) were significantly protected against obesity incidence, relative risks (RR) = 0.25 (0.09−0.72) and RR = 0.47(0.27−0.94), for overall and central obesity, respectively. No significant associations were found between dietary score and obesity incidence rates.Conclusions:In our population, leisure-time PA played a significant role in preventing obesity. In both overall and central obesity, PAL above 60% of the resting metabolic rate and moderate energy intake seem to strike the right balance to prevent obesity.

scholarly journals Metabolic syndrome and cognitive performance in the elderly

2014 ◽  
Vol 87 (1) ◽  
Author(s):  
Marianna Rinaldi ◽  
Giuseppe Graffi ◽  
Salvatore Gallone ◽  
Emma Rabino Massa
Keyword(s):  
Metabolic Syndrome ◽  
Cognitive Performance ◽  
Central Obesity ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Cognitive Status ◽  
Increased Risk ◽  
Males And Females ◽  
The Relationship ◽  
State Examination

Metabolic syndrome (MetS) is a cluster of conditions, each of which represents a risk factor for cardiovascular disease: central obesity, hyperglycemia, dyslipidemia and hypertension. In different recent studies, MetS has been associated with an accelerate cognitive decline in the elderly. The aim of our research was to investigate the relationship between MetS and cognitive performance in 174 Italian elderly people living in Val Cenischia (Piedmont, Italy). Mini mental state examination (MMSE) has been administered to assess the cognitive status of all participants. The prevalence of MetS is 50.3% (51.3 and 49.5% for males and females, respectively). Our results confirm the association between MetS and worse cognitive performance in the elderly: an increased number of MetS components is associated with an increased risk of developing cognitive impairment (odds ratio=1.54; confidence interval 95%:1.04-2.28; P<0.05).

scholarly journals EFEK PEKERJAAN RUMAH TANGGA DALAM PENCEGAHAN PENURUNAN FUNGSI KOGNITIF PADA LANSIA PEREMPUAN BERPENDIDIKAN RENDAH

2017 ◽  
Vol 35 (1) ◽  
Author(s):  
Christina Permata Shalim ◽  
Julia Rahadian ◽  
Yuda Turana
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
Cognitive Decline ◽  
Mental State ◽  
Significant Relationship ◽  
Mini Mental State Examination ◽  
Elderly Women ◽  
Education Level ◽  
Grocery Shopping ◽  
State Examination

   EFFECTS OF HOUSEWORK IN PREVENTION OF COGNITIVE DECLINE IN ELDERLY WOMEN WITH LOW EDUCATIONABSTRACTIntroduction: Physical activities have a role in preventing or slowing down cognitive decline. In Indonesia, physical activity in the elderly women is dominated with house work chores.Aims: This study was aimed to determine the relationship between house chores with cognitive function in elderly women.Methods: A cross sectional analytic descriptive of 65 women aged 60 years and over with highest education level of junior high school that live in Kalianyar, West Jakarta, between October to November 2014. Physical activity was measured by questionnaire about nine housework activities that Indonesian women usually do and cognitive function was assessed by Mini-Mental State Examination (MMSE).Results: In this study of 65 subjects with a mean age of 64.31 years and low education level, there was a significant relationship between the higher amount of physical activity and better cognitive level. The types of physical activity that had a significant relationship with better cognitive function was cooking, grocery shopping, and washing dishes, with the frequency of cooking and grocery shopping had a significant relationship.Discussion: Cooking and grocery shopping activity have a relationship with better cognitive function.Keywords: Cognitive function, daily physical activity, elderly, house choresABSTRAKPendahuluan: Aktivitas fisik dianggap memiliki peran dalam pencegahan atau perlambatan penurunan fungsi kognitif. Di Indonesia, aktivitas fisik pada lansia perempuan didominasi dengan pekerjaan rumah tangga.Tujuan:  Mengetahui  hubungan  aktivitas  fisik pekerjaan  rumah  tangga  terhadap  fungsi  kognitif  pada  lansia perempuan.Metode: Penelitian deskriptif analitik potong lintang terhadap lansia (>60 tahun) perempuan yang mengenyam pendidikanakhir paling tinggi tamat SMP dan tinggal di Kelurahan Kalianyar, Jakarta Barat, pada bulan Oktober-November 2014. Aktivitas fisik diukur menggunakan kuesioner sembilan aktivitas pekerjaan rumah tangga yang dilakukan lansia perempuan Indonesia dan penilaian fungsi kognitif menggunakan Mini-Mental State Examination (MMSE).Hasil: Pada penelitian terhadap 65 subjek dengan rerata usia 64,31 tahun berpendidikan rendah, terdapat hubungan bermakna antara jumlah aktivitas fisik yang dilakukan dengan fungsi kognitif yang lebih baik. Adapun jenis aktivitas fisik yang memiliki hubungan bermakna dengan fungsi kognitif yang lebih baik adalah memasak, berbelanja, dan mencuci piring, terutama frekuensi memasak dan berbelanja yang lebih sering memiliki hubungan secara bermakna.Diskusi: Aktivitas memasak dan berbelanja berhubungan dengan fungsi kognitif yang lebih baik.Kata kunci: Aktivitas fisik sehari-hari, fungsi kognitif, lansia, pekerjaan rumah tangga

scholarly journals Mutual Influence of Psoriasis and Sport

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 161
Author(s):  
Paolo Custurone ◽  
Laura Macca ◽  
Lucrezia Bertino ◽  
Debora Di Mauro ◽  
Fabio Trimarchi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Metabolic Syndrome ◽  
Mutual Influence ◽  
Sport Activity ◽  
Joint Involvement ◽  
Indirect Benefits ◽  
The Impact

The link between psoriasis and sport is a controversial issue. The topic has been poorly investigated, and nowadays there are many unsolved questions, dealing with the role of psoriasis in influencing the sporting habits of patients and, vice versa, the impact of sport activity on course, severity and extent of the disease, with particular regard to the indirect benefits on cardiovascular risk and metabolic syndrome. Moreover, the role of physical activity on patients’ quality of life and the potential limitations on physical activity due to joint involvement have not been well elucidated until now. In this narrative review we will try to provide answers to these queries.

scholarly journals The role of education in mini-mental state examination: a study in Northeast Brazil

2004 ◽  
Vol 62 (2a) ◽  
pp. 206-211 ◽  
Author(s):  
Paulo Roberto de Brito-Marques ◽  
José Eulálio Cabral-Filho
Keyword(s):  
Mental State ◽  
Formal Education ◽  
Mini Mental State Examination ◽  
False Negative ◽  
Low Education ◽  
Main Effects ◽  
State Examination ◽  
Better Than ◽  
Total Test

BACKGROUND: There is evidence that schooling can influence performance in cognitive assessement tests. In developing countries, formal education is limited for most people. The use of tests such as Mini-Mental State Examination (MMSE), could have an adverse effect on the evaluation of illiterate and low education individuals. OBJECTIVE: To propose a new version of MMSE as a screening test to assess Illiterate and low education people. METHOD: A study was carried out enrolling 232 individuals, aged 60 or more of low and middle socio-economic classes. Three groups were studied: Illiterate;1-4 schooling years; 5-8 schooling years. The new version (MMSEmo) consisted of modifications in copy and calculation items of the adapted MMSE (MMSEad) to Portuguese language. The maximum possible score was the same in the two versions: total, 30; copy, 1 and calculation, 5. RESULTS: In the total test score ANOVA detected main effects for education and test, as well as an interaction between these factors: higher schooling individuals performed better than lower schooling ones in both test versions; scores in MMSE-mo were higher than in MMSE-ad in every schooling group. CONCLUSION: Higher schooling levels improve the perfomance in both test versions, the copy and calculation items contributing to this improvement. This might depend on cultural factors. The use of MMSE-mo in illiterate and low school individuals could prevent false positive and false negative cognitive evaluations.

scholarly journals The Use of Neuroscience and Psychological Measurement in England's Court of Protection

2020 ◽  
Vol 11 ◽  
Author(s):  
Andrew McWilliams ◽  
Stephen M. Fleming ◽  
Anthony S. David ◽  
Gareth Owen
Keyword(s):  
Brain Function ◽  
Mini Mental State Examination ◽  
Case Law ◽  
Mental Capacity ◽  
Best Interests ◽  
Quantitative Review ◽  
Mental Capacity Act ◽  
State Examination ◽  
Neuroscience Community

The 2005 Mental Capacity Act of England and Wales provides a description in statute law of a test determining if a person lacks “mental capacity” to take a particular decision and describes how the “best interests” of such a person should be determined. The Act established a new Court of Protection (CoP) to hear cases related to the Act and to rule on disputes over mental capacity. The court gathers a range of evidence, including reports from clinicians and experts. Human rights organisations and others have raised concerns about the nature of assessments for incapacity, including the role of brain investigations and psychometric tests.Aim: Describe use and interpretation of structured measures of psychological and brain function in CoP cases, to facilitate standardisation and improvement of practices, both in the courtroom and in non-legal settings.Method: Quantitative review of case law using all CoP judgments published until 2019. The judgments (n = 408) were read to generate a subset referring to structured testing (n = 50). These were then examined in detail to extract the nature of the measurements, circumstances of their use and features of interpretation by the court.Results: The 408 judgments contained 146 references to structured measurement of psychological or brain function, spread over 50 cases. 120/146 (82.2%) referred to “impairment of mind or brain,” with this being part of assessment for incapacity in 58/146 (39.7%). Measurement referred on 25/146 (17.1%) occasions to “functional decision-making abilities.” Structured measures were used most commonly by psychiatrists and psychologists. Psychological measurements comprised 66.4% of measures. Neuroimaging and electrophysiology were presented for diagnostic purposes only. A small number of behavioural measures were used for people with disorders of consciousness. When assessing incapacity, IQ and the Mini-Mental-State Examination were the commonest measures. A standardised measure of mental capacity itself was employed just once. Judges rarely integrated measurements in their capacity determinations.Conclusion: Structured testing of brain and psychological function is used in limited ways in the Court of Protection. Whilst there are challenges in creating measures of capacity, we highlight an opportunity for the neuroscience community to improve objectivity in assessment, inside and outside the courtroom.

scholarly journals Sex Differences in Rest-Activity Circadian Rhythm in Patients With Metabolic Syndrome

2021 ◽  
Vol 12 ◽  
Author(s):  
Antonino Mulè ◽  
Eleonora Bruno ◽  
Patrizia Pasanisi ◽  
Letizia Galasso ◽  
Lucia Castelli ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Circadian Rhythm ◽  
Metabolic Diseases ◽  
Activity Level ◽  
Activity Count ◽  
Cross Sectional ◽  
The Metabolic Syndrome ◽  
Parametric Analyses ◽  
Rest Activity

Rest-Activity circadian Rhythm (RAR) can be used as a marker of the circadian timing system. Recent studies investigated the relationship between irregular circadian rhythms and cardiovascular risk factors such as hypertension, obesity, and dyslipidemia. These factors are related to the Metabolic Syndrome (MS), a clustering of metabolic risk factors that increases the risk of several cardiovascular and metabolic diseases. This cross-sectional analysis aimed to explore the RAR characteristics by actigraphy in subjects with MS, particularly in relation to sex and MS parameters, using parametric and non-parametric analyses. Distinguishing the characteristics of RAR based on sex could prove useful as a tool to improve the daily level of activity and set up customized activity programs based on each person’s circadian activity profile. This study showed that female participants exhibited higher values than male participants in the Midline Estimating Statistic of Rhythm (MESOR) (243.3 ± 20.0 vs 197.6 ± 17.9 activity count), Amplitude (184.5 ± 18.5 vs 144.2 ± 17.2 activity count), which measures half of the extent of the rhythmic variation in a cycle, and the most active 10-h period (M10) (379.08 ± 16.43 vs 295.13 ± 12.88 activity count). All these parameters are indicative of a higher daily activity level in women. Female participants also had lower Intradaily Variability (IV) than male participants (0.75 ± 0.03 vs 0.85 ± 0.03 activity count), which indicates a more stable and less fragmented RAR. These preliminary data provide the first experimental evidence of a difference in RAR parameters between male and female people with MS.

Sign in / Sign up

Export Citation Format

Share Document