scholarly journals Discovering hidden information in biosignals from patients using artificial intelligence

2020 ◽  
Vol 73 (4) ◽  
pp. 275-284
Author(s):  
Dukyong Yoon ◽  
Jong-Hwan Jang ◽  
Byung Jin Choi ◽  
Tae Young Kim ◽  
Chang Ho Han
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Medical Condition ◽  
Real Life ◽  
Black Box ◽  
Basic Knowledge ◽  
Hidden Information ◽  
Near Future ◽  
Invasive Evaluation

Biosignals such as electrocardiogram or photoplethysmogram are widely used for determining and monitoring the medical condition of patients. It was recently discovered that more information could be gathered from biosignals by applying artificial intelligence (AI). At present, one of the most impactful advancements in AI is deep learning. Deep learning-based models can extract important features from raw data without feature engineering by humans, provided the amount of data is sufficient. This AI-enabled feature presents opportunities to obtain latent information that may be used as a digital biomarker for detecting or predicting a clinical outcome or event without further invasive evaluation. However, the black box model of deep learning is difficult to understand for clinicians familiar with a conventional method of analysis of biosignals. A basic knowledge of AI and machine learning is required for the clinicians to properly interpret the extracted information and to adopt it in clinical practice. This review covers the basics of AI and machine learning, and the feasibility of their application to real-life situations by clinicians in the near future.

scholarly journals A Survey on Bias and Fairness in Machine Learning

2021 ◽  
Vol 54 (6) ◽  
pp. 1-35
Author(s):  
Ninareh Mehrabi ◽  
Fred Morstatter ◽  
Nripsuta Saxena ◽  
Kristina Lerman ◽  
Aram Galstyan
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Real World ◽  
State Of The Art ◽  
Future Directions ◽  
Discriminatory Behavior ◽  
Real World Applications ◽  
Near Future ◽  
Different Sources

With the widespread use of artificial intelligence (AI) systems and applications in our everyday lives, accounting for fairness has gained significant importance in designing and engineering of such systems. AI systems can be used in many sensitive environments to make important and life-changing decisions; thus, it is crucial to ensure that these decisions do not reflect discriminatory behavior toward certain groups or populations. More recently some work has been developed in traditional machine learning and deep learning that address such challenges in different subdomains. With the commercialization of these systems, researchers are becoming more aware of the biases that these applications can contain and are attempting to address them. In this survey, we investigated different real-world applications that have shown biases in various ways, and we listed different sources of biases that can affect AI applications. We then created a taxonomy for fairness definitions that machine learning researchers have defined to avoid the existing bias in AI systems. In addition to that, we examined different domains and subdomains in AI showing what researchers have observed with regard to unfair outcomes in the state-of-the-art methods and ways they have tried to address them. There are still many future directions and solutions that can be taken to mitigate the problem of bias in AI systems. We are hoping that this survey will motivate researchers to tackle these issues in the near future by observing existing work in their respective fields.

Deep Learning Network

2020 ◽  
pp. 1-30
Author(s):  
Bhanu Chander
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Great Power ◽  
Human Being ◽  
Technology Improvement ◽  
Deep Learning Network ◽  
High Level ◽  
Human Brains ◽  
Near Future

Artificial intelligence (AI) is defined as a machine that can do everything a human being can do and produce better results. Means AI enlightening that data can produce a solution for its own results. Inside the AI ellipsoidal, Machine learning (ML) has a wide variety of algorithms produce more accurate results. As a result of technology, improvement increasing amounts of data are available. But with ML and AI, it is very difficult to extract such high-level, abstract features from raw data, moreover hard to know what feature should be extracted. Finally, we now have deep learning; these algorithms are modeled based on how human brains process the data. Deep learning is a particular kind of machine learning that provides flexibility and great power, with its attempts to learn in multiple levels of representation with the operations of multiple layers. Deep learning brief overview, platforms, Models, Autoencoders, CNN, RNN, and Appliances are described appropriately. Deep learning will have many more successes in the near future because it requires very little engineering by hand.

scholarly journals Biological Faithfulness is Unnecessary for Machine Learning

2019 ◽  
Vol 87 (2) ◽  
pp. 27-29
Author(s):  
Meagan Wiederman
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Feature Detection ◽  
Black Box ◽  
Compression Algorithms ◽  
Recent Success ◽  
Human Connectome Project ◽  
Definition Of ◽  
The Brain

Artificial intelligence (AI) is the ability of any device to take an input, like that of its environment, and work to achieve a desired output. Some advancements in AI have focused n replicating the human brain in machinery. This is being made possible by the human connectome project: an initiative to map all the connections between neurons within the brain. A full replication of the thinking brain would inherently create something that could be argued to be a thinking machine. However, it is more interesting to question whether a non-biologically faithful AI could be considered as a thinking machine. Under Turing’s definition of ‘thinking’, a machine which can be mistaken as human when responding in writing from a “black box,” where they can not be viewed, can be said to pass for thinking. Backpropagation is an error minimizing algorithm to program AI for feature detection with no biological counterpart which is prevalent in AI. The recent success of backpropagation demonstrates that biological faithfulness is not required for deep learning or ‘thought’ in a machine. Backpropagation has been used in medical imaging compression algorithms and in pharmacological modelling.

Artificial Intelligence in Causality Healthcare Sector

2020 ◽  
pp. 30-37
Author(s):  
Anandakumar Haldorai ◽  
Shrinand Anandakumar
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Actual World ◽  
Black Box ◽  
Healthcare Sector ◽  
System Property ◽  
Personal Property

The ideology of explainability in Artificial Intelligence (AI) is a prevailing issue which requires attention in the healthcare sector. The issue of explain ability is as ancient as AI and the sophisticated AI signified an understandable retraceable technique. Nonetheless, their demerits were in handling the uncertainties of the actual world. As a result of the advent of probabilistic education, applications have now been considered successful and considerably invisible. Comprehensive AI handles the implementation of traceability and transparency of statistical black box techniques of Machine Learning (ML), certainly Deep Learning (DL). Based on the approach of this paper, it can be argued that there is need for researchers to go beyond the comprehensive AI. To accomplish the dimension of explainability in the healthcare sector, causability aspects have to be incorporated. In the same manner that usability incorporates measurements for the quality of usage, causability incorporates the evaluation of explainable quality. In this research, we provide a number of fundamental definitions to effectively discriminate between causability and explainability, including the application case of DL and human comprehensibility in the field of histopathology. The fundamental contribution of this paper is the ideology of causability that has been differentiated from the notion of explainability whereby causability is based on personal property whereas explainability is the system property.

Virtual Screening Meets Deep Learning

2018 ◽  
Vol 15 (1) ◽  
pp. 6-28 ◽  
Author(s):  
Javier Pérez-Sianes ◽  
Horacio Pérez-Sánchez ◽  
Fernando Díaz
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Virtual Screening ◽  
Great Increase ◽  
New Drugs ◽  
Learning Approach ◽  
Screening Strategies ◽  
Computer Aided ◽  
Recent Developments

Background: Automated compound testing is currently the de facto standard method for drug screening, but it has not brought the great increase in the number of new drugs that was expected. Computer- aided compounds search, known as Virtual Screening, has shown the benefits to this field as a complement or even alternative to the robotic drug discovery. There are different methods and approaches to address this problem and most of them are often included in one of the main screening strategies. Machine learning, however, has established itself as a virtual screening methodology in its own right and it may grow in popularity with the new trends on artificial intelligence. Objective: This paper will attempt to provide a comprehensive and structured review that collects the most important proposals made so far in this area of research. Particular attention is given to some recent developments carried out in the machine learning field: the deep learning approach, which is pointed out as a future key player in the virtual screening landscape.

Artificial Intelligence and Human Rights: Four Realms of Discussion: Summary of Remarks

2020 ◽  
Vol 114 ◽  
pp. 242-245
Author(s):  
Jootaek Lee
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Decision Making ◽  
Deep Learning ◽  
Language Processing ◽  
Human Reasoning ◽  
The Past ◽  
Making Choices ◽  
Data Capturing ◽  
Intensive Procedures

The term, Artificial Intelligence (AI), has changed since it was first coined by John MacCarthy in 1956. AI, believed to have been created with Kurt Gödel's unprovable computational statements in 1931, is now called deep learning or machine learning. AI is defined as a computer machine with the ability to make predictions about the future and solve complex tasks, using algorithms. The AI algorithms are enhanced and become effective with big data capturing the present and the past while still necessarily reflecting human biases into models and equations. AI is also capable of making choices like humans, mirroring human reasoning. AI can help robots to efficiently repeat the same labor intensive procedures in factories and can analyze historic and present data efficiently through deep learning, natural language processing, and anomaly detection. Thus, AI covers a spectrum of augmented intelligence relating to prediction, autonomous intelligence relating to decision making, automated intelligence for labor robots, and assisted intelligence for data analysis.

scholarly journals Explainable AI: A Review of Machine Learning Interpretability Methods

Entropy ◽  
2020 ◽  
Vol 23 (1) ◽  
pp. 18
Author(s):  
Pantelis Linardatos ◽  
Vasilis Papastefanopoulos ◽  
Sotiris Kotsiantis
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Black Box ◽  
Learning Systems ◽  
Model Complexity ◽  
Learning Models ◽  
New Methods ◽  
Industrial Adoption ◽  
Machine Learning Models ◽  
The Way

Recent advances in artificial intelligence (AI) have led to its widespread industrial adoption, with machine learning systems demonstrating superhuman performance in a significant number of tasks. However, this surge in performance, has often been achieved through increased model complexity, turning such systems into “black box” approaches and causing uncertainty regarding the way they operate and, ultimately, the way that they come to decisions. This ambiguity has made it problematic for machine learning systems to be adopted in sensitive yet critical domains, where their value could be immense, such as healthcare. As a result, scientific interest in the field of Explainable Artificial Intelligence (XAI), a field that is concerned with the development of new methods that explain and interpret machine learning models, has been tremendously reignited over recent years. This study focuses on machine learning interpretability methods; more specifically, a literature review and taxonomy of these methods are presented, as well as links to their programming implementations, in the hope that this survey would serve as a reference point for both theorists and practitioners.

scholarly journals Reviewing the relationship between machines and radiology: the application of artificial intelligence

2021 ◽  
Vol 10 (2) ◽  
pp. 205846012199029
Author(s):  
Rani Ahmad
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Health Care Professionals ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Health Science ◽  
Computer Algorithms ◽  
Learning Models ◽  
Specificity And Sensitivity

Background The scope and productivity of artificial intelligence applications in health science and medicine, particularly in medical imaging, are rapidly progressing, with relatively recent developments in big data and deep learning and increasingly powerful computer algorithms. Accordingly, there are a number of opportunities and challenges for the radiological community. Purpose To provide review on the challenges and barriers experienced in diagnostic radiology on the basis of the key clinical applications of machine learning techniques. Material and Methods Studies published in 2010–2019 were selected that report on the efficacy of machine learning models. A single contingency table was selected for each study to report the highest accuracy of radiology professionals and machine learning algorithms, and a meta-analysis of studies was conducted based on contingency tables. Results The specificity for all the deep learning models ranged from 39% to 100%, whereas sensitivity ranged from 85% to 100%. The pooled sensitivity and specificity were 89% and 85% for the deep learning algorithms for detecting abnormalities compared to 75% and 91% for radiology experts, respectively. The pooled specificity and sensitivity for comparison between radiology professionals and deep learning algorithms were 91% and 81% for deep learning models and 85% and 73% for radiology professionals (p < 0.000), respectively. The pooled sensitivity detection was 82% for health-care professionals and 83% for deep learning algorithms (p < 0.005). Conclusion Radiomic information extracted through machine learning programs form images that may not be discernible through visual examination, thus may improve the prognostic and diagnostic value of data sets.

NIMG-46. SYSTEMATIC LITERATURE REVIEW OF ARTIFICIAL INTELLIGENCE ALGORITHMS USING PRE-THERAPY MR IMAGING FOR GLIOMA MOLECULAR SUBTYPE CLASSIFICATION

2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi139-vi139
Author(s):  
Jan Lost ◽  
Tej Verma ◽  
Niklas Tillmanns ◽  
W R Brim ◽  
Harry Subramanian ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Deep Learning ◽  
Literature Review ◽  
Prediction Accuracy ◽  
Molecular Subtypes ◽  
Molecular Subtype ◽  
Tumor Resection ◽  
Support Vector ◽  
Hospital Data

Abstract PURPOSE Identifying molecular subtypes in gliomas has prognostic and therapeutic value, traditionally after invasive neurosurgical tumor resection or biopsy. Recent advances using artificial intelligence (AI) show promise in using pre-therapy imaging for predicting molecular subtype. We performed a systematic review of recent literature on AI methods used to predict molecular subtypes of gliomas. METHODS Literature review conforming to PRSIMA guidelines was performed for publications prior to February 2021 using 4 databases: Ovid Embase, Ovid MEDLINE, Cochrane trials (CENTRAL), and Web of Science core-collection. Keywords included: artificial intelligence, machine learning, deep learning, radiomics, magnetic resonance imaging, glioma, and glioblastoma. Non-machine learning and non-human studies were excluded. Screening was performed using Covidence software. Bias analysis was done using TRIPOD guidelines. RESULTS 11,727 abstracts were retrieved. After applying initial screening exclusion criteria, 1,135 full text reviews were performed, with 82 papers remaining for data extraction. 57% used retrospective single center hospital data, 31.6% used TCIA and BRATS, and 11.4% analyzed multicenter hospital data. An average of 146 patients (range 34-462 patients) were included. Algorithms predicting IDH status comprised 51.8% of studies, MGMT 18.1%, and 1p19q 6.0%. Machine learning methods were used in 71.4%, deep learning in 27.4%, and 1.2% directly compared both methods. The most common algorithm for machine learning were support vector machine (43.3%), and for deep learning convolutional neural network (68.4%). Mean prediction accuracy was 76.6%. CONCLUSION Machine learning is the predominant method for image-based prediction of glioma molecular subtypes. Major limitations include limited datasets (60.2% with under 150 patients) and thus limited generalizability of findings. We recommend using larger annotated datasets for AI network training and testing in order to create more robust AI algorithms, which will provide better prediction accuracy to real world clinical datasets and provide tools that can be translated to clinical practice.

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