Assessing the viability of 3D printed brain models derived from MRI scan data in the communication of complex patterns of hypoxic ischaemic injury to lay-people

Abstract Background: With the outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the effectiveness of providing mask protection is important for people. This article introduces a customized mask retainer to improve the fit performance of face masks.Methods: The participant’s 3D face scans with and without a surgical mask were taken by using a 3D face scanner. The fitter was designed on the 3D face scan data according to the facial anthropometric landmarks, and examined and adjusted on the face scan data with a mask. The fitter was 3D printed using a metal printer for Titanium. The effectiveness of the fitter on augmentation of fit of surgical mask was test according to the Chinese Standard. Tests were repeated three times per participant, and compare differences between groups by Wilcoxon Matched-Pairs Signed-Ranks Test using software (a=.05).Results: The effectiveness test of the retainer on augmentation of fit performance showed a result more than 25-fold increase of overall Fit Factor, which have met the fit requirement for KN95 respirators in China.Conclusions: Fit Factor results indicated that by using the retainer, the Fit Factors of overall and each exercise have significantly increased as compared to that of face mask alone group. It may provide a solution to the shortage of N95 respirators the world is now encountering as fighting against the COVID-19 epidemic.

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1008 Kinematics Model For The Index Finger Mechanism In Flexion/Extension Based On MRI Scan Data

The Proceedings of Conference of Kansai Branch ◽

10.1299/jsmekansai.2006.81._10-8_ ◽

2006 ◽

Vol 2006.81 (0) ◽

pp. _10-8_

Author(s):

Nobuo ABIKO ◽

Ryuichi YOKOGAWA ◽

Hiroshi SHIBATA

Keyword(s):

Index Finger ◽

Mri Scan ◽

Kinematics Model ◽

Flexion Extension ◽

Scan Data

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A novel three-dimensional printed vacuum bell for pectus excavatum treatment: a preliminary study

Journal of Cardiothoracic Surgery ◽

10.1186/s13019-020-01276-y ◽

2020 ◽

Vol 15 (1) ◽

Author(s):

Xicheng Deng ◽

Peng Huang ◽

Jinwen Luo ◽

Jinghua Wang ◽

Liwen Yi ◽

...

Keyword(s):

Pectus Excavatum ◽

Three Dimensional ◽

Optimal Timing ◽

Initial Experience ◽

Improved Outcomes ◽

3D Printed ◽

Logistic Regressions ◽

The Mean ◽

Scan Data

Abstract Objective Conservative treatment with a vacuum bell (VB) for pectus excavatum (PE) has now been gradually popularized as an alternative to surgery. We describe our initial experience with a novel three dimensional (3D) printed VB device. Methods Prospectively collected data of all patients who started using a 3D printed VB in 2018 at our institution were analyzed. Linear and logistic regressions were used to identify factors associated with effectiveness of device usage. Results In total, forty-two patients with a median age of 3.6 years were treated with the device. The median follow-up duration was 11.1 months and the mean initial Depth Ratio (DR) was 0.129. There were no permanent sequelae from side effects. Thirty patients with at least one follow-up body scan data showed varying improvement (z = − 4.569, p = 0.0000). Linear regression suggested that longer usage improved outcomes (R2 = 0.235, p = 0.014). By logistic regression there was a trend of younger ages and less initial DR for better improvement though neither was statistically significant (p = 0.086, 0.078, respectively). Conclusion Our initial experience has shown the 3D printed VB may be as effective as other conventional VBs and could be used as an alternative to surgical treatment for selected patients with PE. More experience and studies with this type of VB are needed to demonstrate its superiority with regard to the 3D printing design and optimal timing and indication for use.

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Evaluation of Mechanical and Physical Properties of Light and Heat Polymerized UDMA for DLP 3D Printer

Sensors ◽

10.3390/s21103331 ◽

2021 ◽

Vol 21 (10) ◽

pp. 3331

Author(s):

Qutaiba Alsandi ◽

Masaomi Ikeda ◽

Yoshinori Arisaka ◽

Toru Nikaido ◽

Yumi Tsuchida ◽

...

Keyword(s):

Mechanical Properties ◽

3D Printer ◽

Additional Heat ◽

Heat Curing ◽

Significant Difference ◽

Light Curing ◽

3D Printed ◽

Internal Adaptation ◽

Scan Data ◽

Urethane Dimethacrylate

The aims of this study were to investigate the feasibility of using a DLP 3D printer to fabricate a crown using scan data before tooth preparation, and to investigate the effect of additional heat curing on the mechanical properties of the urethane dimethacrylate (UDMA)-based 3D printed crown. A silicone fitting test was used to evaluate the internal adaptation of the crown. For ultimate tensile strength (UTS), the specimens were tested after 24 h storage in water at 37 °C or after 10,000 thermal cycles (TC) between 5–55 °C. For shear bond strength (SBS), a PMMA self-curing resin was filled into a Teflon ring mounted onto the polished UDMA specimens. The internal adaptation of the crowns fabricated with cement space was better than those with no cement space. There was no significant difference in UTS between light-curing and additional heat-curing groups after TC. As for the SBS, there was a significant difference after TC between the two groups. Crowns can be fabricated by a DLP 3D printer using pre-preparation scans with a cement space defined in the software. Additional heat curing of the UDMA-based crown reduced residual monomer and improved its mechanical properties.

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Guided endodontic treatment of multiple teeth with dentin dysplasia: a case report

Head & Face Medicine ◽

10.1186/s13005-020-00240-4 ◽

2020 ◽

Vol 16 (1) ◽

Author(s):

Ralf Krug ◽

Julian Volland ◽

Sebastian Reich ◽

Sebastian Soliman ◽

Thomas Connert ◽

...

Keyword(s):

Root Canal ◽

Mineral Trioxide Aggregate ◽

Endodontic Treatment ◽

Apical Region ◽

Type I ◽

Cavity Preparation ◽

Root Canals ◽

3D Printed ◽

Scan Data ◽

Surface Scan

Abstract Background To report the outcome of guided endodontic treatment (GET) of a case of dentin dysplasia with pulp canal calcification (PCC) and apical periodontitis based on the use of a 3D-printed template designed by merging cone-beam computed tomography (CBCT) and surface scan data. Case presentation A 12-year old female with radicular dentin dysplasia type I (DD-1) presented for endodontic treatment. Radiography revealed PCC in all teeth and apical radiolucency in seven teeth (12, 15, 26, 31, 32, 36 and 46). Tooth 36 had the most acute symptoms and was thus treated first by conventional access cavity preparation and root canal detection. Despite meticulous technique, the distal and mesiolingual canals were perforated. The perforations were immediately repaired with mineral trioxide aggregate, and the decision was made to switch to guided endodontic treatment for the remaining 6 teeth. CBCT and intraoral surface scans were acquired and matched using coDiagnostix planning software (Dental Wings Inc.), the respective drill positions for root canal location were determined, and templates were virtually designed and 3D-printed. The template was positioned on the respective tooth, and a customized drill was used to penetrate the calcified part of the root canal and perform minimally invasive access cavity preparation up to the apical region. All root canals were rapidly and successfully located with the templates. At 1-year follow-up, clear signs of apical healing were present in all treated teeth. Conclusions In patients with dentin dysplasia, conventional endodontic therapy is challenging. GET considerably facilitates the root canal treatment of teeth affected by dentin dysplasia.

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Offline RF thermal ablation planning using CT/MRI scan data

The Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1016/j.ejrnm.2014.11.002 ◽

2015 ◽

Vol 46 (1) ◽

pp. 141-150 ◽

Cited By ~ 1

Author(s):

Md. Faruk Ali ◽

Sudhabindu Ray

Keyword(s):

Thermal Ablation ◽

Mri Scan ◽

Scan Data

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Experimental Study of Bio-Polymer Knee Implant

Volume 3: Biomedical and Biotechnology Engineering ◽

10.1115/imece2018-88479 ◽

2018 ◽

Author(s):

Maria Ramos Gonzalez ◽

Brendan O’Toole ◽

Zhiyong Wang

Keyword(s):

Graphic Design ◽

Computer Graphic ◽

Testing Machine ◽

Successful Implementation ◽

Fabrication Method ◽

Normal Walking ◽

Mri Scan ◽

Walking Pattern ◽

3D Printed ◽

Implant Testing

This study tests a custom-designed knee implant made of an FDA approved biomaterial, Chronoflex AR. The implant is designed to cushion the damaged cartilage at the distal end of the femur to reduce knee pain without the removal of cartilage and bone. A patient’s MRI scan was used to render a 3D computer graphic design of the knee. The manufacturing of the implant is conducted by 3D printing the shape of the distal end of the femur and coating it with the biomaterial. This is a preliminary fabrication method. Ultimately, the implant material will be 3D printed or cast in 3D printed molds. A successful implementation of this sort of custom-designed implant would reduce the invasiveness of knee correcting procedures, enable the patient to retain the shape of his or her femoral and tibial anatomy, and reduce the possibility of revision surgeries. A custom knee implant testing machine was designed and fabricated to measure the force, elastic deformation, plastic deformation, wear and fatigue of the component after performing lab tests simulating a normal walking pattern while adhering to ISO standards.

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3D printed rodent skin-skull-brain model: A novel animal-free approach for neurosurgical training

PLoS ONE ◽

10.1371/journal.pone.0253477 ◽

2021 ◽

Vol 16 (6) ◽

pp. e0253477

Author(s):

Marie Bainier ◽

Arel Su ◽

Roger L. Redondo

Keyword(s):

Haptic Feedback ◽

Low Cost ◽

Mouse Skin ◽

3D Models ◽

Stereotactic Techniques ◽

Complete Replacement ◽

Surgery Training ◽

Stereotaxic Surgery ◽

3D Printed ◽

Brain Models

In neuroscience, stereotactic brain surgery is a standard yet challenging technique for which laboratory and veterinary personnel must be sufficiently and properly trained. There is currently no animal-free training option for neurosurgeries; stereotactic techniques are learned and practiced on dead animals. Here we have used three-dimensional (3D) printing technologies to create rat and mouse skin-skull-brain models, specifically conceived for rodent stereotaxic surgery training. We used 3D models obtained from microCT pictures and printed them using materials that would provide the most accurate haptic feedback for each model—PC-ABS material for the rat and Durable resin for the mouse. We filled the skulls with Polyurethane expanding foam to mimic the brain. In order to simulate rodent skin, we added a rectangular 1mm thick clear silicone sheet on the skull. Ten qualified rodent neurosurgeons then performed a variety of stereotaxic surgeries on these rat and mouse 3D printed models. Participants evaluated models fidelity compared to cadaveric skulls and their appropriateness for educational use. The 3D printed rat and mouse skin-skull-brain models received an overwhelmingly positive response. They were perceived as very realistic, and considered an excellent alternative to cadaveric skulls for training purposes. They can be made rapidly and at low cost. Our real-size 3D printed replicas could enable cost- and time-efficient, animal-free neurosurgery training. They can be absolute replacements for stereotaxic surgery techniques practice including but not limited to craniotomies, screw placement, brain injections, implantations and cement applications. This project is a significant step forward in implementing the replacement, reduction, and refinement (3Rs) principles to animal experimentation. These 3D printed models could lead the way to the complete replacement of live animals for stereotaxic surgery training in laboratories and veterinary studies.

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