scholarly journals Serum lipid profile as a prognostic marker in oral submucous fibrosis

2015 ◽  
Vol 27 (4) ◽  
pp. 544
Author(s):  
Kamala Rawson ◽  
BasavarajN Kallalli ◽  
Pavan Gujjar ◽  
ShruthiT Patil ◽  
Sridevi Bhoi ◽  
...  
Author(s):  
K. Mallikarjuna Swamy ◽  
Arati Ganiger

<p class="abstract"><strong>Background:</strong> Oral cancer is one of the most common form of malignancies in India. In many cases it develops at the site of premalignant lesion. Of all oral premalignant conditions, oral submucous fibrosis (OSMF) is of greater concern because of its disabling nature and relative greater chances of malignant transformation. This study is aimed to evaluate the serum lipid profile in OSMF patients as the change in lipid levels may have a diagnostic and prognostic role in the potentially malignant lesions. The present study aimed to evaluate the alteration in serum lipid profile in OSMF and to compare them with healthy controls and to correlate the relationship between pathogenesis of OSMF and lipid profile.</p><p class="abstract"><strong>Methods:</strong> It is a case control study. The study included 50 diagnosed cases of OSMF and 50 matched healthy controls. Fasting venous blood of 3 ml was collected in both cases and controls and serum was separate. Fasting serum lipid profile including total cholesterol (TC), very low density lipoproteins (VLDL), low density lipoproteins (LDL), high density lipoproteins (HDL) and triglycerides (TG) were measured using automatic analyser. Statistical analysis was done using student 't' test .Pearson's correlation  was performed to establish the relationship between study variables.  </p><p class="abstract"><strong>Results:</strong> It was observed that there was statistically significant decrease in serum total cholesterol, TG, LDL, VLDL and HDL observed in patients with OSMF  as compared to the control group (p&lt;0.005).</p><p><strong>Conclusions:</strong> The low lipid levels associated with OSMF indicates that there is inverse relationship between oral cancer and serum lipid profile. Decrease in the lipid levels may be considered as a valuable biochemical marker in the early diagnosis and prognosis of oral malignancy. </p>


2017 ◽  
Vol 4 (58) ◽  
pp. 3531-3534
Author(s):  
Sudhir Kumar Verma ◽  
Vivek Kumar ◽  
Purshottam Singh Yadav ◽  
Nikhil Kumar P Joge ◽  
Ravi Misra

2021 ◽  
Vol 15 (10) ◽  
pp. 2793-2795
Author(s):  
Sobia Siddique ◽  
Asra Afzal ◽  
Muhammad Abul Hasan Ali ◽  
Arooj Khurshid ◽  
Shahida Maqbool ◽  
...  

Objective: To evaluate and compare the levels of plasma total cholesterol, low density lipoprotein, very low density lipoprotein, high density lipoprotein and triglycerides among the oral sub mucous fibrosis patients and control group. Design of the Study: It’s a comparative study done with simple random sampling. Study Settings: The study was done at Oral pathology department of Fatima Jinnah Dental College and Hospital from 01-04-2017 to 30-09-2017. Material and Methods: This research was conducted on 30 clinically diagnosed cases of OSMF and 30 healthy controls. The total lipid profile including triglycerides, total cholesterol, low density lipoprotein cholesterol, high density lipoprotein cholesterol and very low density lipoprotein cholesterol was evaluated. Results of the Study: CTSS The serum lipid values were decreased considerably in the cases than in the controls. Conclusion: There is a converse affiliation between lipid profile and occurrence of oral submucous fibrosis. Consequently the reduced lipid values may be used as a valuable tool in the premature detection of oral submucous fibrosis. Keywords: Oral squamous cell carcinoma, lipids, premalignant condition


2001 ◽  
Vol 120 (5) ◽  
pp. A576-A576
Author(s):  
E FOGEL ◽  
T IMPERIALE ◽  
B DEVERAUX ◽  
S SHERMAN ◽  
J WATKINS ◽  
...  

2007 ◽  
Vol 16 (1) ◽  
Author(s):  
D Sarkar ◽  
SA Latif ◽  
MM Uddin ◽  
J Aich ◽  
SR Sutradhar ◽  
...  

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