scholarly journals The impact of digital imaging in the field of cytopathology

CytoJournal ◽  
2009 ◽  
Vol 6 ◽  
pp. 6 ◽  
Author(s):  
Liron Pantanowitz ◽  
Maryanne Hornish ◽  
Robert A. Goulart

With the introduction of digital imaging, pathology is undergoing a digital transformation. In the field of cytology, digital images are being used for telecytology, automated screening of Pap test slides, training and education (e.g. online digital atlases), and proficiency testing. To date, there has been no systematic review on the impact of digital imaging on the practice of cytopathology. This article critically addresses the emerging role of computer-assisted screening and the application of digital imaging to the field of cytology, including telecytology, virtual microscopy, and the impact of online cytology resources. The role of novel diagnostic techniques like image cytometry is also reviewed.

Author(s):  
Liron Pantanowitz

Automation and emerging information technologies are being adopted by cytology laboratories around the world to augment Pap test screening and improve diagnostic accuracy. Informatics, the application of computers and information systems to information management, is therefore essential for the successful operation of the cytopathology laboratory. This chapter describes how laboratory information management systems can be used to achieve an automated and seamless workflow process. The utilization of software, electronic databases and spreadsheets to perform necessary quality control measures will be discussed. The emerging role of computer assisted screening and application of digital imaging to the field of cervical cytology will be described, including telecytology and virtual microscopy. Finally, this chapter will reflect on the impact of online cytology resources and the emerging role of digital image cytometry.


2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Maria Laura Annunziata ◽  
Mariamaddalena Scala ◽  
Natascia Giuliano ◽  
Salvatore Tagliaferri ◽  
Olga Carmela Maria Imperato ◽  
...  

The aim of this study was to evaluate the impact of vibroacoustic stimulation (VAS) on computerized cardiotocography short-term variability (STV) and approximate entropy (ApEn) in both low- and high-risk pregnancies. VAS was performed on 121 high- and 95 low-risk pregnancies after 10 minutes of continuous quiet, while their FHR parameters were monitored and recorded by cCTG analysis. Fetal heart rate was recorded using a computer-assisted equipment. Baseline FHR, accelerations, decelerations, STV, long-term irregularity (LTI), ApEn, and fetal movements (FMs) were calculated for defined observational periods before VAS and after 10 minutes. Data were also investigated in relationship with the perinatal outcome. In each group of patients, FHR after VAS remained almost unmodified. Fetal movements significantly increased after VAS in both groups. Results show that only in the high-risk pregnancies, the increase of STV and the decrease of ApEn after VAS were significantly associated with favorable perinatal outcomes.


2011 ◽  
Vol 25 (1) ◽  
pp. 1 ◽  
Author(s):  
Abdelbaset Buhmeida ◽  
Yrjo Collan ◽  
Kari Syrjanen ◽  
Seppo Pyrhonen

The role of DNA content as a prognostic factor in colorectal cancer (CRC) is highly controversial. Some of these controversies are due to purely technical reasons, e.g. variable practices in interpreting the DNA histograms, which is problematic particularly in advanced cases. In this report, we give a detailed account on various options how these histograms could be optimally interpreted, with the idea of establishing the potential value of DNA image cytometry in prognosis and in selection of proper treatment. Material consists of nuclei isolated from 50 ƒĘm paraffin sections from 160 patients with stage II, III or IV CRC diagnosed, treated and followed-up in our clinic. The nuclei were stained with the Feulgen stain. Nuclear DNA was measured using computer-assisted image cytometry. We applied 4 different approaches to analyse the DNA histograms: 1) appearance of the histogram (ABCDE approach), 2) range of DNA values, 3) peak evaluation, and 4) events present at high DNA values. Intra-observer reproducibility of these four histogram interpretation was 89%, 95%, 96%, and 100%, respectively. We depicted selected histograms to illustrate the four analytical approaches in cases with different stages of CRC, with variable disease outcome. In our analysis, the range of DNA values was the best prognosticator, i.e., the tumours with the widest histograms had the most ominous prognosis. These data implicate that DNA cytometry based on isolated nuclei is valuable in predicting the prognosis of CRC. Different interpretation techniques differed in their reproducibility, but the method showing the best prognostic value also had high reproducibility in our analysis.


2019 ◽  
Vol 16 (11) ◽  
pp. 4630-4637
Author(s):  
Sudawan Somjai ◽  
Luedech Girdwichai ◽  
Thaniya Pongsiri

The purpose of this paper was to analyze the impact of entrepreneurial education on venture creation along with the mediating roles of entrepreneurial awareness, entrepreneurial mindset, and entrepreneurial skill development. Entrepreneurial Education plays a key role in offering the prospects for graduates to take in the attitude, approach, entrepreneurial mindset and skill development required for the creation of a new venture. For the current paper, the researcher selected the method of quantitative. The researcher of this paper collected data from the Thai students of a few universities. The researcher collected data from those students who were convenient to take part in the study. The findings of this research paper demonstrate that entrepreneurial education is very crucial for students to start a new venture. In this paper, the writer of the paper conducted a quantitative study and collected data from the students of the universities of Thailand. The results of the study depict that all the four hypotheses of this paper were accepted, the universities should provide educational training and education to their students so as to make them aware and develop their mindsets which will assist them in the creation of the venture.


1983 ◽  
Vol 64 (1) ◽  
pp. 13-22 ◽  
Author(s):  
Allan H. Murphy ◽  
Barbara G. Brown

Worded forecasts, which generally consist of both verbal and numerical expressions, play an important role in the communication of weather information to the general public. However, relatively few studies of the composition and interpretation of such forecasts have been conducted. Moreover, the studies that have been undertaken to date indicate that many expressions currently used in public forecasts are subject to wide ranges of interpretation (and to misinterpretation) and that the ability of individuals to recall the content of worded forecasts is quite limited. This paper focuses on forecast terminology and the understanding of such terminology in the context of short-range public weather forecasts. The results of previous studies of forecast terminology (and related issues) are summarized with respect to six basic aspects or facets of worded forecasts. These facets include: 1) events (the values of the meteorological variables): 2) terminology (the words used to describe the events); 3) words versus numbers (the use of verbal and/or numerical expressions); 4) uncertainty (the mode of expression of uncertainty); 5) amount of information (the number of items of information); and 6) content and format (the selection of items of information and their placement). In addition, some related topics are treated briefly, including the impact of verification systems, the role of computer-worded forecasts, the implications of new modes of communication, and the use of weather forecasts. Some conclusions and inferences that can be drawn from this review of previous work are discussed briefly, and a set of recommendations are presented regarding steps that should be taken to raise the level of understanding and enhance the usefulness of worded forecasts. These recommendations are organized under four headings: 1) studies of public understanding, interpretation, and use; 2) management practices; 3) forecaster training and education; and 4) public education.


2019 ◽  
Vol 16 (11) ◽  
pp. 4676-4683
Author(s):  
Boonsri Suteerachai ◽  
Pornkul Suksod ◽  
Sudawan Somjai

Aim of the study: The aim of this paper was to analyze the impact of cognitive entrepreneurial training and education and their impact on business opportunity recognition in Thailand with the moderating role of entrepreneurial passion. This study has four main objectives such as to study the impact of cognitive entrepreneurial training on business opportunity recognition accuracy, to study the impact of entrepreneurial education on business opportunity recognition accuracy, to analyze the role of entrepreneurial passion between cognitive entrepreneurial training and business opportunity recognition accuracy and to analyze the role of entrepreneurial passion between entrepreneurial education and business opportunity recognition accuracy. In the era of rapid development and growth, entrepreneurial education is extremely vital for students. Entrepreneurial passion as well as play an important role in recognizing business opportunities. The process of experiential education facilitates potential business-persons to learn how to identify business opportunities, through developing and building their framework of (Cognitive Opportunity Identification), and through improving their entrepreneurship skills through entrepreneurial learning and education. Methods: Quantitative method and cross sectional time horizon have been used by the researcher in this paper. The researcher gathered data from Thai students. Findings: The study findings suggest that hypothesis 1, 2, 3 and 4, all are accepted. Implications: The programs of entrepreneurial education should provide theoretical understandings to students, facilitating them to make better sense of their pertinent experiences and to transmute them into understanding and knowledge.


Author(s):  
Maria João Marçalo ◽  
Maria do Céu Fonseca ◽  
Ana Alexandra Silva

Este artículo pretende explorar el Aprendizaje de Lenguas Asistido por Ordenador (CALL, Computer-Assisted Language Learning) en Portugal. Para ello, se centrará en el nivel de educación superior. La escasa explotación del CALL en Portugal ha sido ampliamente estudiado en varios informes, por ejemplo, el informe encargado por la UE titulado The Impact of Information and Communications Technologies on the Teaching of Foreign Languages and on the Role of Teachers of Foreign Languages (2002: 5): "The use and employment of ICT in FLT and FLL is far from satisfactory, as ICT resources are traditionally reserved for '(computer) science‘ subjects, and rarely assigned to arts subjects. A general lack of appropriate training of language teachers in meaningful uses of ICT tends to strengthen this trend". Este artículo abordará dichas necesidades centrándose en los resultados de proyectos europeos como POOLS. Analizaremos cuestiones relativas a los materiales en línea que pueden utilizarse para desarrollar contenidos de clases de lengua, hacienda uso de las ventajas del e-Learning.


2011 ◽  
Vol 2011 ◽  
pp. 1-10 ◽  
Author(s):  
Walid E. Khalbuss ◽  
Liron Pantanowitz ◽  
Anil V. Parwani

Rapid advances are occurring in the field of cytopathology, particularly in the field of digital imaging. Today, digital images are used in a variety of settings including education (E-education), as a substitute to multiheaded sessions, multisite conferences, publications, cytopathology web pages, cytology proficiency testing, telecytology, consultation through telecytology, and automated screening of Pap test slides. The accessibility provided by digital imaging in cytopathology can improve the quality and efficiency of cytopathology services, primarily by getting the expert cytopathologist to remotely look at the slide. This improved accessibility saves time and alleviates the need to ship slides, wait for glass slides, or transport pathologists. Whole slide imaging (WSI) is a digital imaging modality that uses computerized technology to scan and convert pathology and cytology glass slides into digital images (digital slides) that can be viewed remotely on a workstation using viewing software. In spite of the many advances, challenges remain such as the expensive initial set-up costs, workflow interruption, length of time to scan whole slides, large storage size for WSI, bandwidth restrictions, undefined legal implications, professional reluctance, and lack of standardization in the imaging process.


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