Antiplasmodial activity of silver nanoparticles: A novel green synthesis approach

In this work, silver nanoparticles have been successfully synthesized using simple and environmentally friendly ‘green synthesis’ method using Indonesian wild honey as mediator. Particle count and size can be optimized by varying the silver nitrate precursor and honey concentration, with the help of sodium hydroxide as pH regulator. Based on X-ray diffraction (XRD) result, crystalline structure of Ag has been confirmed in sample with impurities from AgCl. Based on dynamic light scattering (DLS) and transmission electron microscopy (TEM) results, it was found that the smallest average particles size of AgNPs (117.5 nm from DLS and 11.1 nm from TEM) was obtained at sample with 5% w/v of honey and 0.5 mM of AgNO3.

Download Full-text

Stability Enhancement of Silver Nanoparticles Through Surface Encapsulation via a Facile Green Synthesis Approach and Toxicity Reduction

Journal of Inorganic and Organometallic Polymers and Materials ◽

10.1007/s10904-019-01373-z ◽

2019 ◽

Vol 30 (6) ◽

pp. 1956-1965 ◽

Cited By ~ 1

Author(s):

Mahmuda Akter ◽

A. K. M. Atique Ullah ◽

Md. Shiblur Rahaman ◽

Md. Mostafizur Rahman ◽

Md. Tajuddin Sikder ◽

...

Keyword(s):

Silver Nanoparticles ◽

Green Synthesis ◽

Toxicity Reduction ◽

Stability Enhancement ◽

Synthesis Approach

Download Full-text

A novel green synthesis approach for polymer nanocomposites decorated with silver nanoparticles and their antibacterial activity

The Analyst ◽

10.1039/c4an01301h ◽

2014 ◽

Vol 139 (22) ◽

pp. 5793-5799 ◽

Cited By ~ 26

Author(s):

Guofang Chen ◽

Jingran Lu ◽

Clarissa Lam ◽

Yong Yu

Keyword(s):

Silver Nanoparticles ◽

Antibacterial Activity ◽

Green Synthesis ◽

Polymer Nanocomposites ◽

Polymer Composite ◽

High Purity ◽

Synthesis Strategy ◽

Polymer Colloid ◽

Synthesis Approach

A novel green synthesis strategy was developed for polymer composite spheres decorated with silver nanoparticles, mediated by a polymer colloid support itself, which are very stable and of high purity with excellent antibacterial activity.

Download Full-text

Green Synthesis of Silver Nanoparticles Using Extract of Cilembu Sweet Potatoes (Ipomoea batatas L var. Rancing) as Potential Filler for 3D Printed Electroactive and Anti-Infection Scaffolds

Molecules ◽

10.3390/molecules26072042 ◽

2021 ◽

Vol 26 (7) ◽

pp. 2042

Author(s):

Arie Wibowo ◽

Gusti U. N. Tajalla ◽

Maradhana A. Marsudi ◽

Glen Cooper ◽

Lia A. T. W. Asri ◽

...

Keyword(s):

Silver Nanoparticles ◽

Green Synthesis ◽

Ipomoea Batatas ◽

Conductive Filler ◽

Biological Assessment ◽

Sweet Potatoes ◽

Transmission Electron ◽

3D Printed ◽

Toxic Organic Solvents ◽

Synthesis Approach

Electroactive biomaterials are fascinating for tissue engineering applications because of their ability to deliver electrical stimulation directly to cells, tissue, and organs. One particularly attractive conductive filler for electroactive biomaterials is silver nanoparticles (AgNPs) because of their high conductivity, antibacterial activity, and ability to promote bone healing. However, production of AgNPs involves a toxic reducing agent which would inhibit biological scaffold performance. This work explores facile and green synthesis of AgNPs using extract of Cilembu sweet potato and studies the effect of baking and precursor concentrations (1, 10 and 100 mM) on AgNPs’ properties. Transmission electron microscope (TEM) results revealed that the smallest particle size of AgNPs (9.95 ± 3.69 nm) with nodular morphology was obtained by utilization of baked extract and ten mM AgNO3. Polycaprolactone (PCL)/AgNPs scaffolds exhibited several enhancements compared to PCL scaffolds. Compressive strength was six times greater (3.88 ± 0.42 MPa), more hydrophilic (contact angle of 76.8 ± 1.7°), conductive (2.3 ± 0.5 × 10−3 S/cm) and exhibited anti-bacterial properties against Staphylococcus aureus ATCC3658 (99.5% reduction of surviving bacteria). Despite the promising results, further investigation on biological assessment is required to obtain comprehensive study of this scaffold. This green synthesis approach together with the use of 3D printing opens a new route to manufacture AgNPs-based electroactive with improved anti-bacterial properties without utilization of any toxic organic solvents.

Download Full-text

Structural and electrical behaviours of PEDOT:PSS thin films in presence of negatively charged gold and silver nanoparticles: A green synthesis approach

Synthetic Metals ◽

10.1016/j.synthmet.2021.116848 ◽

2021 ◽

Vol 279 ◽

pp. 116848

Author(s):

Suman Sarkar ◽

Ashim Chandra Bhowal ◽

Raghuram Kandimalla ◽

Sarathi Kundu

Keyword(s):

Thin Films ◽

Silver Nanoparticles ◽

Green Synthesis ◽

Gold And Silver Nanoparticles ◽

Synthesis Approach

Download Full-text

DEXTRAN SULFATE STABILIZED SILVER NANOPARTICLE: NEXT GENERATION EFFICIENT THERAPY FOR CANCER

International Journal of Applied Pharmaceutics ◽

10.22159/ijap.2020v12i1.35327 ◽

2019 ◽

pp. 59-63

Author(s):

SHARMILA CHANDRAN ◽

THILAGAVATHY PONNUSAMY ◽

DINESH BHEEMAN ◽

RANJITH KUMAR RAJAMANI ◽

CHANDAR SHEKAR BELLAN

Keyword(s):

Silver Nanoparticles ◽

Green Synthesis ◽

Anticancer Activity ◽

Cell Line ◽

Functional Groups ◽

Dextran Sulfate ◽

Xrd Analysis ◽

Psidium Guajava ◽

Synthesis Approach ◽

Mcf 7

Objective: Synthesize silver nanoparticles using a green synthesis approach and encapsulate silver nanoparticles with a naturally occurring polymer, particularly of an-hydroglucose type, like dextran sulfate sodium salt and to study its anticancer activity. Methods: Green synthesis approach is been employed in the synthesis of silver nanoparticles using Psidium guajava leaf extract. The nanoparticles were then encapsulated with dextran sulfate biopolymer and the nanoparticles were subjected to different characterization techniques. The structure of the synthesized nanoparticles was analyzed using X-ray diffraction analysis, the presence of different functional groups was analyzed by FTIR studies. Size and morphology of the prepared nanoparticles were investigated using FESEM analysis. Anticancer activity of the synthesized nanoparticles was tested against the MCF-cell line. Results: The XRD analysis shows the crystalline nature of the synthesized nanoparticles. The stretching and vibrating modes of different functional groups were confirmed by FTIR result. The SEM image confirmed the presence of spherical shaped nanoparticles and the TEM image confirmed the average size of the particles to be around 24 nm. The Ag-DS NPs showed 91% cell inhibition for the concentration of 100 μg/ml, indicating the cytotoxicity of the nanoparticles against MCF-7 cell line. Conclusion: Dextran sulfate stabilized silver nanoparticles show potent anticancer activity against MCF-7 cell line.

Download Full-text

Synergistic Antibacterial Efficacy of Biogenic Synthesized Silver Nanoparticles using Ajuga bractosa with Standard Antibiotics: A Study Against Bacterial Pathogens

Current Pharmaceutical Biotechnology ◽

10.2174/1389201020666191001123219 ◽

2020 ◽

Vol 21 (3) ◽

pp. 206-218 ◽

Cited By ~ 2

Author(s):

Sadia Nazer ◽

Saiqa Andleeb ◽

Shaukat Ali ◽

Nazia Gulzar ◽

Tariq Iqbal ◽

...

Keyword(s):

Silver Nanoparticles ◽

Green Synthesis ◽

Bacterial Pathogens ◽

Potential Effect ◽

Innovative Technology ◽

Multi Drug Resistance ◽

Phytochemical Screening ◽

Cell Proliferation Inhibition ◽

Agar Well Diffusion Assay ◽

Scanning Electron

Background: Multi-drug resistance in bacterial pathogens is a major concern of today. Green synthesis technology is being used to cure infectious diseases. Objectives: The aim of the current research was to analyze the antibacterial, antioxidant, and phytochemical screening of green synthesized silver nanoparticles using Ajuga bracteosa. Methods: Extract of A. bracteosa was prepared by maceration technique. Silver nanoparticles were synthesized using A. bracteosa extract and were confirmed by UV-Vis spectrophotometer, Scanning Electron Microscope (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). The antibacterial, anti-biofilm, cell proliferation inhibition, TLC-Bioautography, TLC-Spot screening, antioxidant, and phytochemical screening were also investigated. Results: UV-Vis spectrum and Scanning electron microscopy confirmed the synthesis of green nanoparticles at 400 nm with tube-like structures. FTIR spectrum showed that functional groups of nanoparticles have a role in capping and stability of AgNP. Agar well diffusion assay represented the maximum antibacterial effect of ABAgNPs against Escherichia coli, Klebsiella pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, and Pseudomonas aeruginosa at 0.10 g/mL concentration compared to ABaqu. Two types of interactions among nanoparticles, aqueous extract, and antibiotics (Synergistic and additive) were recorded against tested pathogens. Crystal violet, MTT, TLC-bio-autography, and spot screening supported the findings of the antibacterial assay. Highest antioxidant potential effect in ABaqu was 14.62% (DPPH) and 13.64% (ABTS) while 4.85% (DPPH) and 4.86% (ABTS) was recorded in ABAgNPs. Presence of phytochemical constituents showed pharmacological importance. Conclusion: It was concluded that green synthesis is an innovative technology in which natural products are conjugated with metallic particles and are used against infectious pathogens. The current research showed the significant use of green nanoparticles against etiological agents.

Download Full-text