scholarly journals Web Tool for Estimating the Cancer Hazard Rates in Aging

2014 ◽  
Vol 13 ◽  
pp. CIN.S19777 ◽  
Author(s):  
Tengiz Mdzinarishvili ◽  
Alexander Sherman ◽  
Oleg Shats ◽  
Simon Sherman

A computational approach for estimating the overall, population, and individual cancer hazard rates was developed. The population rates characterize a risk of getting cancer of a specific site/type, occurring within an age-specific group of individuals from a specified population during a distinct time period. The individual rates characterize an analogous risk but only for the individuals susceptible to cancer. The approach uses a novel regularization and anchoring technique to solve an identifiability problem that occurs while determining the age, period, and cohort (APC) effects. These effects are used to estimate the overall rate, and to estimate the population and individual cancer hazard rates. To estimate the APC effects, as well as the population and individual rates, a new web-based computing tool, called the CancerHazard@Age , was developed. The tool uses data on the past and current history of cancer incidences collected during a long time period from the surveillance databases. The utility of the tool was demonstrated using data on the female lung cancers diagnosed during 1975–2009 in nine geographic areas within the USA. The developed tool can be applied equally well to process data on other cancer sites. The data obtained by this tool can be used to develop novel carcinogenic models and strategies for cancer prevention and treatment, as well as to project future cancer burden.

2009 ◽  
Vol 47 (2-3) ◽  
Author(s):  
R. Tatevossian

To evaluate the completeness of modern knowledge on historical seismicity it is necessary to know the general geopolitical and socio-cultural background in the country. It determines the possibility to record the evidence of an earthquake and conserve the record in original form for a long time-period. The potential duration of historical earthquake study in Russia is assessed based on these considerations. Certain stages of earthquake study in Russia have been detected. Specific problems of seismicity studies of low active areas are discussed as an example of Russian platform. The value of each (even moderate magnitude) event becomes crucial for seismic hazard assessment in such territories. A correct identification of event nature (tectonic earthquake or exogenous phenomena - landslides, karsts, etc.) is practically impossible without using primary sources with detailed descriptions. Occurrence of modern earthquakes can be used to assess the accuracy of historical seismicity knowledge.


Perceptions ◽  
2018 ◽  
Vol 4 (2) ◽  
pp. 7
Author(s):  
Effi Booth

This paper was presented in History 3697, fall semester, 2017, a mid-level required writing course designed to link the methods of oral history with the study of issues in the contemporary history of the non-western world. The issue for all of us in this course was social change in recent times. I chose to examine the degree of acceptance of gays in Jamaica, in an era of great change in sexual mores throughout the world. I read the literature; I interviewed Julian, a recent immigrant from Jamaica, and I drew conclusions based on integrating the scholarly material with the interview revelations. The findings were important both for understanding (the lack of) change in sexual attitudes in Jamaica, and the importance of analysis of the individual and the collective together, of the interview and the scholarly data examined together. The individual, at least my interviewee, and the society, are currently resistant to change. The main conclusion: changes in sexual mores in other areas of the world are taking place at rates very different from, and, specifically in Jamaica, at rates much slower than, those in the USA.


2020 ◽  
Vol 10 (3) ◽  
pp. 20190074 ◽  
Author(s):  
Matthew Beaumont

This article explores the emergence, in late nineteenth-century Britain and the USA, of the ‘insomniac’ as a distinct pathological and social archetype. Sleeplessness has of course been a human problem for millennia, but only since the late-Victorian period has there been a specific diagnostic name for the individual who suffers chronically from insufficient sleep. The introductory section of the article, which notes the current panic about sleep problems, offers a brief sketch of the history of sleeplessness, acknowledging the transhistorical nature of this condition but also pointing to the appearance, during the period of the Enlightenment, of the term ‘insomnia’ itself. The second section makes more specific historical claims about the rise of insomnia in the accelerating conditions of everyday life in urban society at the end of the nineteenth century. It traces the rise of the insomniac as such, especially in the context of medical debates about ‘neurasthenia’, as someone whose identity is constitutively defined by their inability to sleep. The third section, tightening the focus of the article, goes on to reconstruct the biography of one exemplary late nineteenth-century insomniac, the American dentist Albert Kimball, in order to illustrate the claim that insomnia was one of the pre-eminent symptoms of a certain crisis in industrial and metropolitan modernity as this social condition was lived by individuals at the fin de siècle .


Author(s):  
Надежда Степановна Коровина

В данной статье предпринята попытка на основе конкретного сказочного сюжета о Безручке (СУС 706) исследовать особенности взаимодействия фольклорных произведений народов, не родственных этнически, но тесно общаюшихся на протяжении длительного времени и имеющих близкие культурные традиции. При рассмотрении данного вопроса использовалась методика сравнительного анализа, позволяющая установить, каким образом международный сказочный сюжет становится культурным достоянием народа коми, т. е. прояснить историю национального сказочного репертуара. В процессе анализа коми сказок о Безручке выявлено сходство с русскими вариантами в области содержания, в типах героев и способах их создания, развитии действия и последовательности эпизодов. В результате автор приходит к выводу о том, что сюжет о Безручке (СУС 706) заимствован у русских. Одновременно в статье отмечен тот факт, что рассмотренные варианты коми сказок имеют свою специфику и не создают впечатления однообразия. Это происходит за счет того, что постоянные элементы, представляющие композиционный стержень сюжета, во-первых, обрастают своеобразными деталями, которые придают повествованию национальный колорит. Именно в них отражается быт, привычки, обычаи народа коми. Во-вторых, своеобразие каждого варианта во многом зависят от индивидуального стиля, степени исполнительского мастерства, творческой манеры, отношения к данному сюжету того или другого исполнителя. В-третьих, именно в отдельных его вариантах сказываются социальные, временные различия, в совокупности своей отражающие исторические изменения сказки In this article an attempt is made on the basis of a specific fairy-tale story about «The Maiden without Hand» (CIP 706) to explore the features of the interaction of folk works of peoples who are not related ethnically, but who closely communicated for a long time and have close cultural traditions. When regarding this issue, we consider it appropriate to use the methodology of comparative analysis, since it is the comparative study of Russian and Komi variants of the fairy-tale plot that allows us to establish how the international fairy-tale plot becomes the cultural heritage of the Komi people, to clarify the history of the national fairy-tale repertoire. In all analyzed Komi tales about the Maiden without hand there is a similarity with the Russian variants in the development of the action, the sequence of episodes, the type of characters, their characteristics, the common ideological content. The structural and typological analysis allows us to conclude that the plot about «The Maiden without hand» (CIP 706) was borrowed from the Russians. However, the considered variants of Komi fairy tales do not create the impression of monotony because the constant elements that represent the compositional core, firstly, acquire peculiar details that give the narrative a national flavor. They reflect the life, habits and customs of the Komi people. Secondly, the originality of each option depends largely on the individual style, the degree of performing skills, creative manner, attitude to the story of a particular artist. Thirdly, it is in its individual options where the impact of class, time differences manifest themselves reflecting the historical changes of the tale.


2021 ◽  
Author(s):  
Emily McKibbon

This thesis addresses the use of a set of photographs of returned prisoners of war (POWs) published both as tipped-in albumen prints and as wood engravings in six different publications from 1864 and 1865, including three versions of Narrative of Privations and Sufferings of United States Officers and Soldiers while Prisoners of War in the Hands of the rebel Authorities, one pamphlet, and two magazine articles, The discussion focuses on the dissemination of these images by the United States Sanitary Commission, the ways in which the photographs were presented in the individual publications that contained them, the decisions that the engravers made in translating the photographs into wood engravings and the visual codes that informed the photographs and the related engravings. The illustrated essay situates these photographs and wood engravings within the political context of the American Civil War and the history of photography in the 1860s. The dissemination of photographic imagery via wood engravings before the widespread use of halftone reproductions, beginning in the 1880s, is presently under researched. The paper encourages consideration of wood engravings when examining the history of photographic reproduction during this transitional time period.


2019 ◽  
Vol 29 (1) ◽  
pp. 89-95 ◽  
Author(s):  
Christine D Czoli ◽  
Christine M White ◽  
Jessica L Reid ◽  
Richard J OConnor ◽  
David Hammond

IntroductionHeated tobacco products (HTPs), such as IQOS, have been introduced in a growing number of international markets. However, little is known about perceptions of HTP products among youth.MethodsData are from wave 1 of the International Tobacco Control Youth Tobacco and E-cigarette Survey (2017), a web-based cohort survey of people aged 16–19 years from Canada, England and the USA. Respondents (n=12 064) were shown an image of IQOS and asked about their awareness, interest in trying and susceptibility to trying the product. Youth awareness, interest in trying and susceptibility to trying IQOS were analysed using descriptive statistics, and logistic regression models were used to examine correlates of these outcomes.ResultsOverall, 7.0% of youth reported awareness of IQOS (England=5.6%, Canada=6.4% and USA=9.1%) and 38.6% expressed interest in trying the product (England=41.8%, Canada=33.0% and USA=40.9%). Within each country, all key outcomes varied by smoking status: greater proportions of youth who were currently smoking or had a history of smoking reported being aware of, interested in trying and susceptible to trying IQOS. Interest and susceptibility to trying IQOS were associated with male sex, current tobacco use and current e-cigarette use. Across all countries, susceptibility to trying IQOS (25.1%) was higher than for tobacco cigarettes (19.3%), but lower than for e-cigarettes (29.1%).ConclusionsAwareness of HTPs, such as IQOS, is emerging among youth in Canada, England and the USA. Interest in trying these products is very high among smokers, but also present among non-smokers.


Author(s):  
Ilkka Niiniluoto

Jaakko Hintikka was a Finnish philosopher who developed important new methods and systems in mathematical and philosophical logic. Over a distinguished career in universities in Finland and the USA, he was one of the most cited analytic philosophers and published prolifically in mathematical and philosophical logic, philosophy of language, formal epistemology, philosophy of science and history of philosophy. Hintikka was a pioneer of possible-worlds semantics, epistemic logic, inductive logic, game-theoretical semantics, the interrogative approach to inquiry and independence-friendly logic. He was an expert on Aristotle, Leibniz, Kant, Peirce and Wittgenstein. He also influenced philosophy as a successful teacher and the long-time editor of the journal Synthese.


2014 ◽  
pp. 1475-1495 ◽  
Author(s):  
Tami Echavarria Robinson

Continuing education for librarians and library staff is a need all libraries must consider for the effective professional development of their human resources and the functioning of their libraries. Similar concerns regarding the needs and barriers to obtaining ongoing continuing education are found across different types of libraries and in different regions of the country. Although studied separately and in different regions of the country, among concerns of library school media specialists documented in studies, results are similar to those revealed in a survey of Inland Northwest Library Council (INCOL) librarians in public, academic, and special libraries. Consortia offering continuing education are not well documented in the literature, but examples that exist reveal a feasible, collaborative, effective resource as a means to provide for these needs in member libraries. The history of these consortia is not only important as a means of documentation of their existence, but more so of their value and usefulness proven over a long time period. INCOL, in the Inland Northwest region of the Pacific Northwest of the United States, is a model of such a consortium that continues to be relevant after more than 30 years of offering ongoing continuing education to its constituency.


Author(s):  
Adriana Veríssimo Serrão ◽  

A complex controversy, the debate between Max Stimer and Ludwig Feuerbach is certainly one of the most interesting in the history of Contemporary ideas and surpasses, by the fruitfulness contained therein, the short time period in which it unfolded. The article considers the controversy in a particular aspect: the understanding of the category of the individual, showing the incompatibility between Unique-individual (Stimer) and the individual as being in relation (Feuerbach).


2018 ◽  
Vol 43 ◽  
Author(s):  
Frank Osterhage

For some time now, there has been a lively debate about reurbanisation in Germany with regard to trends in spatial development. At the same time, the consequences of spatially imbalanced development can be observed in many regions. In large metropolitan areas in particular, the renewed appeal of cities has made living space scarce and expensive. There is extensive investment in residential construction and infrastructure, yet the first signs of a further shift in the trend are starting to emerge. It is against this background that this paper investigates migratory movements in the state of North Rhine-Westphalia, covering a period of more than four decades. The resulting change in the distance between place of residence and the nearest major centre is calculated for each case of migration in the time period under investigation. By aggregating the individual values, an indicator is generated that can be used to identify different phases of spatial concentration and deconcentration. The results remind us that for a long time the predominant forces in migratory movements were centrifugal. This makes the transition to the spatial concentration phase that took place in the past decade, and that can be precisely traced from the values obtained, all the more striking. In the final years of the period under investigation, the results are significantly influenced by the handling of the publicly-directed migration of refugees and asylum-seekers within the state. If municipalities with admission facilities for these groups that exhibit anomalous migration data are excluded from the analysis, deconcentration processes appear in fact to be gaining the upper hand again in North Rhine-Westphalia. Renewed momentum in residential suburbanisation in the areas surrounding the major centres is behind this current development. Deceleration of the migratory losses from more peripheral municipalities can also be observed, however.


Sign in / Sign up

Export Citation Format

Share Document