GROWTH-DEPENDENT CHANGES IN BLOOD UREA NITROGEN LEVELS IN LINCOLN AND SOUTHDOWN LAMBS

1969 ◽  
Vol 49 (2) ◽  
pp. 197-204 ◽  
Author(s):  
H. Mukhoty ◽  
W. Combs ◽  
T. D. D. Groves

The concentration of blood plasma urea nitrogen (BUN) was measured at bi-weekly intervals in four groups of growing Lincoln and Southdown lambs which received the same ration throughout their growth period. BUN increased with age and weight in each group. Although all groups showed similar changes in BUN with age, BUN concentration increased at 0.73 × 10−2, 0.88 × 10−2, 0.91 × 10−2, and 1.23 × 10−2 mg per kg of body weight gained in the case of Lincoln males, Lincoln females, Southdown males, and Southdown females, respectively. The average rates of gain for these groups were 0.33, 0.28, 0.26 and 0.20 kg per day, respectively. It appeared from these studies that at any given weight, the more mature animals at that weight tended to have higher BUN concentrations and a higher rate of increase of BUN with weight.

2007 ◽  
Vol 85 (4) ◽  
pp. 1006-1013 ◽  
Author(s):  
N. E. Sunny ◽  
S. L. Owens ◽  
R. L. Baldwin ◽  
S. W. El-Kadi ◽  
R. A. Kohn ◽  
...  

1961 ◽  
Vol 65 (6) ◽  
pp. 805-807 ◽  
Author(s):  
M. A. GALIN ◽  
H. D. NANO ◽  
R. A. DAVIDSON

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Nai Nurazizah ◽  
Nai Nurazizah

The research was conducted to know the effect of noni fruit extract supplemented by Cu and Zn on blood cholesterol and  egg yolk cholesterol, creatinin, and blood urea nitrogen of sentul chicken. The research was done from August until October 2019. Samples test was held in Physiology and Biochemistry Laboratory, Animal Husbandry Faculty, Padjadjaran University, Sumedang. The methods used experimental with a Completely Randomized Design (CRD) and the effect of treatment using Analysis of  Varience (ANOVA) followed by Orthogonal Polynomial. The treatment consisted of five kind with five repetitions, those are to =  without adding noni fruit extract and  Cu, Zn , t1= Ration + 60 mg/kg extract noni fruit suplemented Cu 0,06 mg and Zn 1,5 mg, t2= Ration+ 180 mg/kg extract fruit noni suplemented Cu 0,18 mg and Zn 3,0 m, t3= Ration + 240 mg/kg extract fruit noni suplemented Cu 0,24 mg and Zn 4,5 mg, t4= Ration + 360 mg/kg extract fruit noni suplemented Cu 0,36 and Zn 6,0 mg. The result showed that the effect of giving 360 mg/kg noni extract suplemented Cu 0,36 and Zn 6,0 mg was significant effect  decreasing blood cholesterol levet but non significant  decreasing egg yolk cholesterol, creatinin, and blood urea nitrogen levels of Sentul Chicken. Keywords:  noni fruit extract, cholesterol, urea, creatinin, blood, egg yolk              cholesterol, sentul chicken, mineral Cu and ZnThe research was conducted to know the effect of noni fruit extract supplemented by Cu and Zn on blood cholesterol and  egg yolk cholesterol, creatinin, and blood urea nitrogen of sentul chicken. The research was done from August until October 2019. Samples test was held in Physiology and Biochemistry Laboratory, Animal Husbandry Faculty, Padjadjaran University, Sumedang. The methods used experimental with a Completely Randomized Design (CRD) and the effect of treatment using Analysis of  Varience (ANOVA) followed by Orthogonal Polynomial. The treatment consisted of five kind with five repetitions, those are to =  without adding noni fruit extract and  Cu, Zn , t1= Ration + 60 mg/kg extract noni fruit suplemented Cu 0,06 mg and Zn 1,5 mg, t2= Ration+ 180 mg/kg extract fruit noni suplemented Cu 0,18 mg and Zn 3,0 m, t3= Ration + 240 mg/kg extract fruit noni suplemented Cu 0,24 mg and Zn 4,5 mg, t4= Ration + 360 mg/kg extract fruit noni suplemented Cu 0,36 and Zn 6,0 mg. The result showed that the effect of giving 360 mg/kg noni extract suplemented Cu 0,36 and Zn 6,0 mg was significant effect  decreasing blood cholesterol levet but non significant  decreasing egg yolk cholesterol, creatinin, and blood urea nitrogen levels of Sentul Chicken. Keywords:  noni fruit extract, cholesterol, urea, creatinin, blood, egg yolk              cholesterol, sentul chicken, mineral Cu and Zn


2015 ◽  
Vol 5 (10) ◽  
pp. 339 ◽  
Author(s):  
Adewale Adetutu ◽  
Olubukola Sinbad Olorunnisola ◽  
Kazeem Iyanda

Background: Weakening of renal function from reactive oxygen species generated during malaria infection is one of the prominent causes of death in prevalent regions. The potential toxicity of free radical generated by malaria parasites are counteracted by a large number of cytoprotective phytochemicals. Therefore, this study examined the influence of extracts of five selected antimalarial plants (Azadirachta indica, Parquetina nigrescens, Citrus paradisi, and Khaya senigalensis) on reduction of inflammation in renal tissue, blood urea nitrogen and creatinine levels during malaria infection using Plasmodium berghei infected Swiss albino mice. For in vivo assay, mice were inoculated with 1 × 107 parasitized erythrocytes and plant extracts were subsequently administered orally at 100 mg/kg body weight once a day for 17 consecutive days. The chemo-suppressive and prophylaxis effects of the plant extracts against P. berghei were investigated and compared with those of standard antimalarial drug, chloroquine. Tail bleeding was performed to check the percentage parasitaemia by making a thin film smear on a slide, stained in Giemsa. The numbers of parasited cells against the unparasitised cells were counted using a microscope. The effect of malaria infection on renal tissue was assessed by histological analysis and measurement of blood urea nitrogen and creatinine levels in plasma. At 100 mg/kg per body weight, aqueous extract of K. senegalensis, A. indica, C. paradisi and P. nigrescens exhibited significant (p<0.05) percentage inhibition and chemo-suppressive effects in comparison with the chloroquine treated mice. The result of the untreated group showed that there was a significant (p<0.05) increase in the level of plasma urea while the level of the groups treated with plants extract stabilized the level of urea and creatinine in the blood. Also there was a pathological lesion on the kidney tissue of untreated group whereas the group treated with aqueous extract of A. indica, Khaya senegalensis and C. paradisi showed no lesion. It can be established that the extracts can protect and preserve renal function during malaria infection. These findings justified the use of the extracts in traditional medicine practice, for the treatment of malaria infection.  Keywords: Plasmodium berghei, antimalarial plants, renal function, antiplasmodium


2020 ◽  
Vol 17 (2) ◽  
pp. 181
Author(s):  
NOVIANE ANGRELLA ◽  
ROOSTANTIA INDRAWATI ◽  
LESTARI DEWI

<p><strong>ABSTRACT</strong></p><p><strong>Background:</strong><em> </em><em>Virgin Coconut Oil </em>(VCO) is a functional product that is highly favored and have been widely applied in the everyday lives of society. The increase of the frequencies and duration of VCO consumption is suspected that VCO could negatively impact the target organ. The kidney is a vital organ in the human body, it is responsible for clearing out the residual waste products of metabolism in the body. The evalution of the kidney’s function can be done through the measurement of creatinine and blood urea nitrogen. The purpose of this study is to determine the effect of VCO administration on kidney function.</p><p><strong>Method</strong>: 24 male wistar rats that are divided into 4 groups, which are listed as follows, K(-) or a negative-controlled group, P(1) or the first group of rats that are given VCO with a dose of 2mL/200gr of the rats’ total BW/day, P(2) or the second group of rats that are given VCO with a dose of 3mL/200gr of the rats’ total BW/day,  and P(3) or the third group of rats that are given VCO with a dose of 4mL/200gr of the rats’ total BW/day for 28 day</p><p><strong>Results</strong>: Administrating<strong> </strong>VCO with a dose of 2mL/200gr and 3mL/200gr of the rats’ total BW/day does not affect the blood’s creatinine level while with a dose of 4mL/200gr of the rats’ total BW/day decreases the blood’s creatinine level. Administrating VCO with a dose of 2 mL/200gr, 3 mL/200gr, and 4 mL/200gr of the rats’ total BW/day does not affect the level of blood urea nitrogen.</p><p><strong>Conclusion: </strong>Administration of VCO dose of 4 mL / 200 g BW rat / day significantly decreased blood creatinine levels in experimental animals, while other doses did not affect the creatinine levels or blood urea nitrogen levels<strong></strong></p><p><strong>Keywords</strong><strong>:</strong> <em>Virgin Coconout Oil </em>(VCO), cretinine, blood urea nitrogen.</p>


2005 ◽  
Vol 5 ◽  
pp. 652-660 ◽  
Author(s):  
Natarajan Ranganathan ◽  
Beena Patel ◽  
Pari Ranganathan ◽  
Joseph Marczely ◽  
Rahul Dheer ◽  
...  

The present study was to test the hypothesis that selected bacteria instilled into the gastrointestinal tract could help in converting nitrogenous wastes accumulated due to renal insufficiency into nontoxic compounds; thereby, ameliorating the biochemical imbalance. Herein we describe a prospective, blinded, placebo-controlled pilot study, using 5/6thnephrectomized Sprague Dawley rat as a chronic renal failure model. The study group consisted of 36 nephrectomized and 7 non-nephrectomized (control) rats. After two-week nephrectomy stabilization, cohorts of six nephrectomized rats were fed casein-based diet plus one of the following regimens: (A) Control, (B) Placebo (casein-based diet without probiotics), (C)Bacillus pasteurii, (D) Sporolac®, (E) Kibow cocktail, (F) CHR Hansen Cocktail, and (G) ECONORMTM. Subsequently, blood (retro-orbital) and urine (collected for measurements of blood urea-nitrogen and creatinine respectively), body weight and bacterial counts (feces) were obtained at regular intervals. The study end-points were to determine if any of the probiotic dietary supplements facilitated, (1) decreased blood concentrations of uremic toxins, (2) altered renal function, and (3) prolonged survival. After 16 weeks of treatment, regimens C and D significantly prolonged the life span of uremic rats, in addition to showing a reduction in blood urea-nitrogen levels, concluding that supplementation of probiotic formulation to uremic rats slows the progression of azotemia, which may correlate with prolonged life span of uremic rats. Derivative trials of probiotic treatment of larger animals and humans will further assess the potential role of probiotic formulations in delaying the onset and clinical severity of clinical illness at different stages of renal failure.


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