scholarly journals Antifungal Activity of Compounds obtained from Sawdust and Stem Bark of Sasswood Tree (Erythrophleum suaveolens) on Wood Rot Fungi

2019 ◽  
Vol 23 (9) ◽  
pp. 1685
Author(s):  
D.O. Ekhuemelo ◽  
F.S. Agbidye ◽  
J.V. Anyam ◽  
C. Ekhuemelo ◽  
J.O. Igoli
Keyword(s):  
Antifungal Activity ◽  
Stem Bark ◽  
Wood Rot Fungi

scholarly journals Seasonal effects and antifungal activity from bark chemical constituents of Sterculia apetala (Malvaceae) at Pantanal of Miranda, Mato Grosso do Sul, Brazil

2015 ◽  
Vol 45 (3) ◽  
pp. 283-292 ◽  
Author(s):  
Fernanda Mussi FONTOURA ◽  
Rosemary MATIAS ◽  
Juliane LUDWIG ◽  
Ademir Kleber Morbeck de OLIVEIRA ◽  
José Antonio Maior BONO ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Chemical Constituents ◽  
Chemical Study ◽  
Stem Bark ◽  
Seasonal Effects ◽  
Chemical Components ◽  
Phytochemical Analysis ◽  
Wet Season ◽  
Mycelium Growth ◽  
Mato Grosso

In the Southern Pantanal, the hyacinth macaw (Anodorhynchus hyacinthinus), an endangered species, often chooses the manduvi tree (Sterculia apetala) as a nesting site, because of its physical properties. In addition, the chemical composition of the wood may also contribute to a nesting selection by the hyacinth macaws. The objective of this study was to determine the main chemical components of S. apetala bark for two seasons, and evaluate its fungicidal potential. Bark samples from S. apetala trees with and without nests of A. hyacinthinus were collected in January (wet season) and August (dry season) of 2012. The inhibition of mycelium growth (MGI) from tree samples with and without nests were assessed using a phytochemical analysis to evaluate their antifungal activity against Trichoderma sp. Phytochemical analysis confirmed the presence of phenolic compounds and flavonoids. In both seasons, samples obtained from nested trees had higher content of total phenols than those collected from non-nested trees. The average content of total flavonoids was higher in January for samples with nest and in August for samples without nest. All selected samples showed antifungal activity, and those with nest collected in August (peak of hyacinth macaw breeding) resulted in an MGI of 51.3%. Therefore, this percentage, related to the content of flavonoids and the presence of coumarins, may influence the reproductive success of hyacinth macaws and other species of birds, in this region. This is the first chemical study report with the stem bark of S. apetala.

Pentacyclic Triterpenes and Other Constituents from Ficus cordata (Moraceae)

2008 ◽  
Vol 63 (11) ◽  
pp. 1335-1338 ◽  
Author(s):  
Herve M. P. Poumale ◽  
Rodrigue T. Kengap ◽  
Jean Claude Tchouankeu ◽  
Felix Keumedjio ◽  
Hartmut Laatsch ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Secondary Metabolites ◽  
Betulinic Acid ◽  
Nmr Spectra ◽  
2D Nmr ◽  
Stem Bark ◽  
Published Data ◽  
Pentacyclic Triterpenes ◽  
2D Nmr Spectra ◽  
Lupeol Acetate

Abstract Two new pentacyclic triterpenes 8,26-cyclo-urs-21-en-3β, 20β-diol (1) and 3β-acetoxy-8.26- cyclo-ursan-20β-ol (2) together with 3-friedelanone, oleanolic acid, betulinic acid, lupeol acetate, α- and β-amyrine, S.SJ^'-tetrahydroxyflavane, and 3,5,7,3',4'-pentahydroxyflavane were isolated from the stem bark of Ficus cordata (Moraceae). The structures of these secondary metabolites were established using ID and 2D NMR spectra and by comparison with published data or with authentic samples. Compounds 1 and 2 exhibited weak antibacterial and no antifungal activity.

Antifungal Activity and Phytochemical Analysis of Column Chromatographic Fractions of Stem Bark Extracts of Ficus sycomorus L. (Moraceae)

2007 ◽  
Vol 2 (2) ◽  
pp. 209-215 ◽  
Author(s):  
S.W. Hassan ◽  
M. Lawal ◽  
B.Y. Muhammad ◽  
R.A. Umar ◽  
L.S. Bilbis ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Stem Bark ◽  
Phytochemical Analysis ◽  
Ficus Sycomorus ◽  
Column Chromatographic

scholarly journals A New Benzophenanthridine Alkaloid from Caloncoba Glauca

2017 ◽  
Vol 12 (3) ◽  
pp. 1934578X1701200
Author(s):  
Jabar B.P.A.A. Agbo ◽  
James D.S. Mpetga ◽  
Raphael Bikanga ◽  
Roland T. Tchuenguem ◽  
Rolande B.N. Tsafack ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Antifungal Activity ◽  
Stem Bark ◽  
Mass Spectrometric ◽  
First Report ◽  
Mass Spectrometric Evidence ◽  
Benzophenanthridine Alkaloid

Three alkaloids including a new one, N-formyldihydrochelerythrine (1), together with four other known compounds were isolated from the stem bark of Caloncoba glauca. The structure of the new compound was elucidated from spectroscopic and mass spectrometric evidence. This is the first report of alkaloids from the genus Caloncoba. Sesamin (4) [MIC = 256 μg/mL ( Candida albicans) and dihydrochelerythrine (2) [MIC = 32 ( C. albicans and C. parapsilosis), and 128 μg/mL ( C. krusei)] had moderate to weak antifungal activity.

scholarly journals Antifungal activity in vitro of Sapranthus microcarpus (Annonaceae) against phytopathogens

2018 ◽  
Author(s):  
Iván De-la-Cruz-Chacón ◽  
Nora Yazmin López-Fernández ◽  
Christian Anabí Riley-Saldaña ◽  
Marisol Castro Moreno ◽  
Alma Rosa González-Esquinca
Keyword(s):  
Antifungal Activity ◽  
Fungal Pathogens ◽  
Plant Pathogens ◽  
Stem Bark ◽  
Antimicrobial Activities ◽  
Curvularia Lunata ◽  
Root Bark ◽  
Inhibitory Activities ◽  
Alkaloid Extracts

Background and Aims: The phytochemistry study of Annonaceae has intensified in the last decades due to the discovery of secondary metabolites with antimicrobial activities. The inhibitory activities of extracts and compounds from these species for phytopathogens are less known. The antifungal activity of Sapranthus microcarpus was determined in vitro against six fungal pathogens of important crops.Methods: Hexane, methanol, and alkaloid extracts of the leaves and root and stem bark of S. microcarpus were evaluated to determine whether they could inhibit the mycelial growth of the phytopathogens. The combined activity of the most active extracts for each phytopathogen was also determined. The alkaloid liriodenine was isolated and identified as an antifungal principle.Key results: All extracts inhibited the growth of the six phytopathogens to some extent. The root bark alkaloid extract showed the highest activity. Fusarium oxysporum f. sp. lycopersici and Curvularia lunata were the most sensitive phytopathogens. Liriodenine was active against all the plant pathogens (minimum inhibitory concentrations of 125-500 nmol ml-1).Conclusions: Sapranthus microcarpus is a native natural resource with great phytochemical potential.

scholarly journals Antibacterial and antifungal activity of Moringa oleifera stem bark

2013 ◽  
pp. 109-117 ◽  
Author(s):  
Md Shafiqur Rahman ◽  
Laila Zerin ◽  
MN Anwar
Keyword(s):  
Antifungal Activity ◽  
Ethyl Acetate ◽  
Pathogenic Bacteria ◽  
Moringa Oleifera ◽  
Ethyl Acetate Extract ◽  
Pathogenic Fungi ◽  
Stem Bark ◽  
Shigella Dysenteriae ◽  
Antibacterial And Antifungal Activity ◽  
Antibacterial And Antifungal

Petroleum ether, chloroform, ethyl acetate and carbon tetrachloride extracts of Moringa oleifera stem bark were studied for their antimicrobial activities against eleven human pathogenic bacteria (Shigella dysenteriae, S. sonnei, Salmonella typhi, S. paratyphi, Bacillus subtilis, B. megaterium, B. cereus, Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Vibrio cholerae) and four human pathogenic fungi (Aspergillus niger, A. ochraceus, A. ustus and Candida albicans) using disc diffusion and poisoned food method, respectively. Chloroform and ethyl acetate extracts exhibited moderate to good antibacterial and antifungal activity against all the pathogens tested. The ethyl acetate extract exhibited the largest zone of inhibition (21 mm in diameter with 2000 mg/disc extract) against S. sonnei. The highest inhibition of fungal radial mycelial growth (52. 00% with 100 mg extract/ml medium) was recorded against C. albicans with ethyl acetate extract. The ethyl acetate extract exhibited the lowest MIC (750 mg/ml) against B. megaterium, S. dysenteriae, V. cholerae and E. coli. For fungi, the lowest MIC was 500 mg/ml against C. albicans with crude extract of ethyl acetate. DOI: http://dx.doi.org/10.3329/cujbs.v3i1.13411 The Chittagong Univ. J. B. Sci.,Vol. 3(1&2):109-117, 2008

Inhibition of Chitin Synthase 2 and Antifungal Activity of Lignans from the Stem Bark of Lindera erythrocarpa

Planta Medica ◽  
2007 ◽  
Vol 73 (7) ◽  
pp. 679-682 ◽  
Author(s):  
Eui Hwang ◽  
Yun Lee ◽  
Sang Lee ◽  
Woon Yeo ◽  
Jae Moon ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Stem Bark ◽  
Chitin Synthase

scholarly journals Potentiating Antifungal Activity of Fluconazole or Nystatin with Methanol Bark Extract of Harungana madagascariensis Stem Bark

2017 ◽  
Vol 9 (5) ◽  
Author(s):  
Ebelle R. E. ◽  
Mouokeu R. S. ◽  
Assam J PA ◽  
Hopogap M. L. ◽  
Masoohe A M. ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Bacterial Infections ◽  
Stem Bark ◽  
Oral Route ◽  
Experimental Models ◽  
Bark Extract ◽  
Infection Model ◽  
Phytochemical Analysis ◽  
Broth Microdilution Method

The therapeutic failures and the increasingly high costs of treating resistant bacterial infections calls for alternative means of care. The present study was initiated to evaluate the antifungal properties of the Harungana madagascariensis methanol barks extract and potent interactions with some usual drugs. The extract was prepared by maceration of the dry stem bark powder in methanol. Phytochemical analysis was carried out by colorimetric assays. Antifungal activity as well as interactions between extract, Nystatin or Fluconazole was evaluated by broth microdilution method. The therapeutic efficacies of H. madagascariensis extract and Fluconazole – extract mixture as compared to Fluconazole extract was studied in experimental models of oral and vulvovaginal candidiasis in rats by oral route. Results showed that methanol extract of H. madagascariensis stem barks had antifungal activity ranging from 128 to 1024 µg/ml. This extract also had a fungicidal activity on all of the tested yeasts. Moreover, the extract presented in vitro synergetic and additive interactions with Nystatin and Fluconazole. In both oral and vaginal infection model, all the treatment significantly reduced (P less than 0.05) the number of colony formant unit (UFC) of C. albicans compared with untreated control. Moreover, significant decrease in the percentage of animals showing positive cultures was observed in rats treated with Fluconazole-extract mixture. In both therapeutic efficacy studies, the histological findings confirmed the microbiological results. The results of this study constitute a base for the usage of H. madagascariensis stem barks in association with Fluconazole to overcome yeast infection.

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