How Theory Influences Treatment and Prevention Practice with the Family

2020 ◽  
pp. 3-3 ◽  
Author(s):  
Tamara Ilic ◽  
Milan Rogosic ◽  
Bojan Gajic ◽  
Jelena Aleksic

Background. Urinary capillariosis in dogs is caused by Capillaria plica (syn. Pearsonema plica), a ubiquitous parasitic nematode resembling a string which belongs to the family Capillariidae. It parasitizes the feline, canine and musteline urinary bladder, and has been found in ureters and renal pelvises as well. C. plica has an indirect life cycle, with earthworms (Lumbricina) as intermediate hosts and domestic and wild animals (dog, cat, fox and wolf) as primary hosts. Infection of primary hosts occurs via ingestion of earthworms that contain infective first stadium (L1) larvae. An alternative path of infection for primary hosts is assumed to be ingestion of soil contaminated by infectious larvae derived from decomposed earthworms. Infection is mostly asymptomatic, but the clinical picture presents with pollakiuria, dysuria, haematuria, polydipsia, incontinence and/or fever. Scope and Approach. The aim of this review is to highlight the importance of urinary capillariosis in dogs. Since the health care of wild and domestic carnivores is extremely important, this review provides information about the morphology, biology and epizootiology of the C. plica nematode. Due to the importance of this disease for clinicians and increased disease prevalence during the last decade in many countries, this review presents the latest information on the pathogenesis, clinical signs, diagnosis, treatment and prevention of this infection. Key Findings and Conclusions. Capillariosis is usually accidentally diagnosed due to the nonspecific clinical signs and there is no treatment of choice. Practitioners should consider latent urinary capillariosis infection as a possible cause while examining for urinary tract diseases.


2012 ◽  
Vol 80 (11) ◽  
pp. 3786-3794 ◽  
Author(s):  
Angela E. Reeves ◽  
Mark J. Koenigsknecht ◽  
Ingrid L. Bergin ◽  
Vincent B. Young

ABSTRACTThe indigenous microbial community of the gastrointestinal (GI) tract determines susceptibility toClostridium difficilecolonization and disease. Previous studies have demonstrated that antibiotic-treated mice challenged withC. difficileeither developed rapidly lethalC. difficileinfection or were stably colonized with mild disease. The GI microbial community of animals with mild disease was dominated by members of the bacterial familyLachnospiraceae, while the gut community in moribund animals had a predominance ofEscherichia coli. We investigated the roles of murineLachnospiraceaeandE. colistrains in colonization resistance againstC. difficilein germfree mice. MurineLachnospiraceaeandE. coliisolates were cultured from wild-type mice. The ability of each of these isolates to interfere withC. difficilecolonization was tested by precolonizing germfree mice with these bacteria 4 days prior to experimentalC. difficilechallenge. Mice precolonized with a murineLachnospiraceaeisolate, but not those colonized withE. coli, had significantly decreasedC. difficilecolonization, lower intestinal cytotoxin levels and exhibited less severe clinical signs and colonic histopathology. Infection of germfree mice or mice precolonized withE. coliwithC. difficilestrain VPI 10463 was uniformly fatal by 48 h, but only 20% mortality was seen at 2 days in mice precolonized with theLachnospiraceaeisolate prior to challenge with VPI 10463. These findings confirm that a single component of the GI microbiota, a murineLachnospiraceaeisolate, could partially restore colonization resistance againstC. difficile. Further study of the members within theLachnospiraceaefamily could lead to a better understanding of mechanisms of colonization resistance againstC. difficileand novel therapeutic approaches for the treatment and prevention ofC. difficileinfection.


Author(s):  
A. J. Giri ◽  
A. N. Salve ◽  
J. K. Dhumal ◽  
P. R. Doifode ◽  
Aijaz A. Sheikh ◽  
...  

In present study, COVID-19 is a type of coronavirus disease belonging to the family Corona viridae. The disease is thought to originate from bats and was spread to people through an unknown medium in Wuhan, China. Ideally, the condition is spread by mouthful of air or close interaction with infected droplets that have an incubation period between two and fourteen days. Today, there are thousands of infections and deaths that have been caused by the disease. Moreover, the symptoms of the disease include fever, cough, sneezing, sore throat, difficulty breathing, and tiredness. Additionally, the diagnosis of the disease starts by gathering samples of the upper and lower respiratory tracts of the infected person. This paper provides in-depth information on COVID-19 as it discusses the disease epidemiology, transmission, clinical features, diagnosis, treatment and prevention.


2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Jyotika Singh ◽  
Pradeep Kumar Gupta

Drug addiction has become a worldwide problem and the leading cause of death. The global problem of addiction and drug abuse is responsible for millions of deaths and millions of new cases of HIV every year. In recent years, India is seeing a rising trend in drug addiction. The most common use of drug in India is alcohol, followed by cannabis and opiates. Drug use, whether licit or illicit, causes serious health problems in individuals. The National level survey conducted on drug use in India indicated that prevalence of drug abuse among males in the general population is significant. Drug abuse among women exists. Despite the fact that more men use drugs than women, the impact of drug use tends to be greater on women, because women lack access to care for drug dependence. Economic burden, disturbed family environment, violence, and psychological problems are other consequences of drug abuse in the family. Adolescent drug abuse is another major area of concern because more than half of the person’s with substance use disorder are introduced to drugs before the age of 15 years. At present, there exists a significant gap in service delivery. The current paper highlights the causes of drug abuse, and describes the treatment and prevention of drug abuse and addiction for proper management of the problem.


2021 ◽  
pp. 44-48
Author(s):  
Sergey Ivanovich Dvoinikov ◽  
Larisa Arkadyevna Karaseva

The crisis of a unified infrastructure of the health care system requires a transformation of the provision of medical care by bringing it directly to the patient, to the family, combining the elements of treatment and prevention, medical and social assistance at its level. All over the world, the important role of primary medical and social care (PHC) in protecting the health of the population is recognized, while the main place in the organization of out-of-hospital primary medical care is general medical practice. By actively modifying certain aspects of family life, GPs have the opportunity to make wider use of the possibilities of preventive medicine, in many ways to prevent the onset and development of diseases.


2016 ◽  
pp. 143-145
Author(s):  
Nataliia Medvedovskaya ◽  
Zoreslava Povch

The objective: justification of need of the organization of introduction of measures for timely identification of an ophthalmic hypertension in practice of the family doctor for timely diagnosis of glaucoma, the prevention of development of her terminal stage became a research objective. Patients and methods. Outpatient and polyclinic units of five healthcare institutions of the city of Kiev in which primary help by the principles of the general medical practice – family medicine is given became scientific base of a research. Forms of account No. 12 «The report on the diseases registered at patients who live in the district of service of treatment and prevention facility» and questionnaires of a sociological research of risk factors of glaucoma (820 questionnaires) were primary material. Achievement of goals of a research demanded use of a complex of methods of a research, a basis for which was a systemic approach, namely: bibliosemantic, sociological, medico-statistical methods. Results. Of a research it has turned out that prevalence of glaucoma continues to increase enough in high gear (for 14,9% from 2010 to 2014) that proves relevance of a problem of the prevention of a blindness and a low vision because of glaucoma in Ukraine and in the near future. Owning knowledge of modern risk factors which has the proved influence on formation of an oftalmogipertenziya, and over time and glaucomas, physicians of primary contact can actively form risk groups on glaucoma that will allow to unify and to individualize at the same time preventively – improving, medical and diagnostic medical care in each case and to objectify assessment of her results in dynamics. Conclusion. Interaction in form of cooperation of the family doctor and ophthalmologist within the competences allows to perform effective long accounting of patients, preventing loss of visual functions by them for the account, first of all timely diagnosis of a disease (at an early stage), possible correction of the available risk factors of origin and progressing of glaucoma.


1983 ◽  
Vol 28 (12) ◽  
pp. 968-968
Author(s):  
Oakley Ray ◽  
Bill Anderson

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Xiu-Feng Huang ◽  
Li Sun ◽  
Chunwu Zhang ◽  
Zhenni Zhou ◽  
Hui Chen ◽  
...  

Gout is a common inflammatory arthritis triggered by monosodium urate deposition after longstanding hyperuricemia. In the general community, the disease is largely polygenic in genetic architecture, with many polymorphisms having been identified in gout or urate-associated traits. In a small proportion of cases, rare high penetrant mutations associated with monogenic segregation of the disease in families have been demonstrated to be disease causative. In this study, we recruited a two-generation pedigree with early-onset gout. To elucidate the genetic predisposition, whole-exome sequencing (WES) was performed. After comprehensive variant analyses and cosegregation testing, we identified a missense variant (c.277C>A, p.L93M) in SLC16A9, an extremely rare variant in genetic databases. Moreover, in silico assessments showed strong pathogenicity. This variant cosegregated with the disease phenotype perfectly in the family and is located in a highly conserved functional domain. A few studies supported our results of the association between SLC16A9 and gout and serum urate levels. In conclusion, we provide the first evidence for the association of rare missense in SLC16A9 with early-onset gout. These findings not only expand our current understanding of gout but also may have further implications for the treatment and prevention of gout.


Author(s):  
Anastasia S. Argutina ◽  
S. Yu. Kosyuga

For the development a program for the prevention of dentoalveolar anomalies for children’s dental clinic, there were investigated features of the orthodontic status in children of primary school age and factors affecting its formation. The authors have been proposed preventive measures for two levels of the implementation: conjointly with teaching staff of the schools and involvement of the family (the so-called «school level»), as well as the treatment and prevention activity of children’s specialists from the dental polyclinic (polyclinic level). The mentioned measures have been structured and formulated by authors as «the preventive program». The implementation of the program for the prevention of dentoalveolar anomalies in basic medical practice showed it pronounced clinical and social effect


Sign in / Sign up

Export Citation Format

Share Document