A Case Showing Some Implications of Short Treatment

2021 ◽  
pp. 391-422
Author(s):  
Charles Berg
Keyword(s):  
Short Treatment

Language and Vision in the Epinician Poets

2017 ◽  
Author(s):  
David Fearn
Keyword(s):  
Material Culture ◽  
The Other ◽  
Visual Narrative ◽  
Short Treatment ◽  
Narrative Style ◽  
Cultural Terms ◽  
Language And Vision

This chapter explores the ways in which the other two contemporary epinician poets, Simonides and Bacchylides, use aesthetics and material culture as a way of drawing attention to their own individual and distinctive poetic voices and poetic agendas. Their affinities with and differences from Pindar are explored on the strength of the available evidence. Simonides’ Danae fragment receives detailed coverage, interpreted in visual-cultural terms in relation to Simonides’ ongoing fame as the original commentator on the relation between art and text. Discussion then turns to Bacchylides, and the predominance of a visual narrative style in his work. The argument covers not only epinician material but also an interesting but understudied fragmentary dithyramb. The focus then returns to Pindar with a short treatment of the themes of vision and visual and material culture in Nemean 10.

Behavioural hearing tactics: a controlled trial of a short treatment programme

1997 ◽  
Vol 35 (6) ◽  
pp. 523-530 ◽  
Author(s):  
Gerhard Andersson ◽  
Malin Green ◽  
Lennart Melin
Keyword(s):  
Controlled Trial ◽  
Treatment Programme ◽  
Short Treatment

Kinetin-Mediated Stimulation of Accumulation of Buckwheat Flavonoids in the Dark

1983 ◽  
Vol 38 (9-10) ◽  
pp. 711-718 ◽  
Author(s):  
U. Margna ◽  
T. Vainjärv
Keyword(s):  
Anthocyanin Biosynthesis ◽  
Flavonoid Biosynthesis ◽  
Accumulation Rates ◽  
Sharp Rise ◽  
Short Treatment ◽  
Exogenous Substrate ◽  
Percent Increase ◽  
High Level ◽  
Fold Stimulation ◽  
Stimulation Of

A short treatment of excised buckwheat cotyledons with a solution of kinetin lead to an up to 9-fold stimulation of anthocyanin biosynthesis, to an about 50 percent increase in the accumula­tion of rutin, and to an about 30 percent increase, on the average, in the accumulation of C-glycosylflavones in the treated material during its posttreatment incubation in the dark. When the treated cotyledons were incubated in a solution of ʟ--phenylalanine anthocyanin accumulation in the dark practically attained the same high level as it was observed in the illuminated cotyledons fed with exogenous ʟ--phenylalanine. In experiments with l4C-labelled L-phenylalanine kinetin induced a sharp rise in the labelling (resp. in the utilization of exogenous substrate for biosynthesis) of anthocyanins and rutin in the dark and a slight increase in the radioactivity of C-glycosylflavones. Similar labelling changes occurred in the illuminated cotyledons. However, both kinetin and light still more effectively promoted biosynthetic use of the endogenous sub­strate. As a result the relative portion of flavonoids formed from exogenous L-phenylalanine under these conditions showed a decrease as compared with the ratio of precursor use in the un­treated cotyledons. The results show that low accumulation rates of anthocyanins and other flavo­noids in the dark are conditioned by the limited access of substrate (ʟ--phenylalanine) molecules to the flavonoid enzymes lending further support to the idea that flavonoid biosynthesis is normally controlled at the substrate rather than at the enzymic level.

scholarly journals Green Solvents as an Alternative to DMF in ZIF-90 Synthesis

Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1573
Author(s):  
Aljaž Škrjanc ◽  
Ciara Byrne ◽  
Nataša Zabukovec Logar
Keyword(s):  
Room Temperature ◽  
Product Yield ◽  
Solvent Exchange ◽  
Green Solvents ◽  
Zeolitic Imidazolate Framework ◽  
Short Treatment ◽  
Molar Ratios ◽  
Primary Particles ◽  
High Product Yield

The use of green solvents as an alternative to dimethylformamide (DMF) in the synthesis of zeolitic imidazolate framework-90 (ZIF-90) was investigated. Two biobased aprotic dipolar solvents CyreneTM and γ-valerolactone (GVL) proved to successfully replace DMF in the synthesis at room temperature with a high product yield. While the CyreneTM—based product shows reduced porosity after activation, the use of GVL resulted in materials with preserved crystallinity and porosity after activation, without prior solvent exchange and a short treatment at 200 °C. The primary particles of 30 nm to 60 nm in all products further form agglomerates of different size and interparticle mesoporosity, depending on the type and molar ratios of solvents used.

scholarly journals In Pursuit of an Effective Treatment: the Past, Present and Future of Clinical Trials in Inclusion Body Myositis

2021 ◽  
Author(s):  
A. M. Snedden ◽  
J. B. Lilleker ◽  
H. Chinoy
Keyword(s):  
Clinical Practice ◽  
Effective Treatment ◽  
Inclusion Body ◽  
Therapeutic Effect ◽  
Outcome Measures ◽  
Inclusion Body Myositis ◽  
Cytotoxic T Cells ◽  
Treatment Options ◽  
Trial Methodology ◽  
Short Treatment

Abstract Purpose of review No clinical trial in sporadic inclusion body myositis (IBM) thus far has shown a clear and sustained therapeutic effect. We review previous trial methodology, explore why results have not translated into clinical practice, and suggest improvements for future IBM trials. Recent findings Early trials primarily assessed immunosuppressive medications, with no significant clinical responses observed. Many of these studies had methodological issues, including small participant numbers, nonspecific diagnostic criteria, short treatment and/or assessment periods and insensitive outcome measures. Most recent IBM trials have instead focused on nonimmunosuppressive therapies, but there is mounting evidence supporting a primary autoimmune aetiology, including the discovery of immunosuppression-resistant clones of cytotoxic T cells and anti-CN-1A autoantibodies which could potentially be used to stratify patients into different cohorts. The latest trials have had mixed results. For example, bimagrumab, a myostatin blocker, did not affect the 6-min timed walk distance, whereas sirolimus, a promotor of autophagy, did. Larger studies are planned to evaluate the efficacy of sirolimus and arimoclomol. Summary Thus far, no treatment for IBM has demonstrated a definite therapeutic effect, and effective treatment options in clinical practice are lacking. Trial design and ineffective therapies are likely to have contributed to these failures. Identification of potential therapeutic targets should be followed by future studies using a stratified approach and sensitive and relevant outcome measures.

The Sovereign’s Beatitude

2021 ◽  
pp. 009059172110420
Author(s):  
Zoltan Balazs
Keyword(s):  
Image Of God ◽  
The Political ◽  
Short Treatment ◽  
Divine Sovereignty ◽  
Conceptual Coherence ◽  
Political Sovereignty ◽  
Human Happiness ◽  
Theological Perspective ◽  
And Behavior ◽  
The Image Of God

Though it may sound awkward to ask whether the political sovereign is happy or unhappy, the question is relevant to political theory, especially within a political theological perspective. Because man was created in the image of God, human happiness needs to be a reflection of divine beatitude, and as divine sovereignty is, at least analogically, related to political sovereignty, the conceptual coherence is secured. The main argument is, however, that the analogy does not hold. I shall show how St Thomas Aquinas’s short treatment of God’s beatitude may mislead us about power, fame, riches, and dignity being essential to happiness, based on an analysis of Franz Kafka’s major novel, The Castle, and a few other writings by him. I shall argue that our tradition of political thinking and behavior remains ambivalent on this issue. The political sovereign is born out of our unhappy condition, yet its power, fame, riches, and glory suggests to us that it has appropriated our happiness. But for this very reason it cannot be happy, and it therefore suggests a false analogy between the divine and the political sovereign. It is fundamentally at variance with our happiness, which incites us to abandon, reject, and eventually, kill it.

scholarly journals Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells.

1994 ◽  
Vol 126 (1) ◽  
pp. 247-258 ◽  
Author(s):  
O Ayalon ◽  
H Sabanai ◽  
M G Lampugnani ◽  
E Dejana ◽  
B Geiger
Keyword(s):  
Endothelial Cells ◽  
Plasma Membrane ◽  
Vascular System ◽  
Adherens Junctions ◽  
Microscopic Analysis ◽  
Membrane Receptors ◽  
Temporal Organization ◽  
Cell Junctions ◽  
Short Treatment ◽  
Cell Cell

The integrity of the endothelial layer, which lines the entire cavity of the vascular system, depends on tight adhesion of the cells to the underlying basement membrane as well as to each other. It has been previously shown that such interactions occur via membrane receptors that determine the specificity, topology, and mechanical properties of the surface adhesion. Cell-cell junctions between endothelial cells, in culture and in situ, involve both Ca(2+)-dependent and -independent mechanisms that are mediated by distinct adhesion molecules. Ca(2+)-dependent cell-cell adhesion occurs mostly via members of the cadherin family, which locally anchor the microfilament system to the plasma membrane, in adherens junctions. Ca(2+)-independent adhesions were reported to mainly involve members of the Ig superfamily. In this study, we performed three-dimensional microscopic analysis of the relative subcellular distributions of these two endothelial intercellular adhesion systems. We show that cadherins are located at adjacent (usually more apical), yet clearly distinct domains of the lateral plasma membrane, compared to PECAM-1. Moreover, cadherins were first organized in adherens junctions within 2 h after seeding of endothelial cells, forming multiple lateral patches which developed into an extensive belt-like structure over a period of 24 h. PECAM-1 became associated with surface adhesions significantly later and became progressively associated with the cadherin-containing adhesions. Cadherins and PECAM-1 also differed in their detergent extractability, reflecting differences in their mode of association with the cytoskeleton. Moreover, the two adhesion systems could be differentially modulated since short treatment with the Ca2+ chelator EGTA, disrupted the cadherin junctions leaving PECAM-1 apparently intact. These results confirm that endothelial cells possess distinct intercellular contact mechanisms that differ in their spatial and temporal organization as well as in their functional properties.

Physical Studies on a Short-Treatment-Distance Cesium-137 Teletherapy Unit

Radiology ◽  
1960 ◽  
Vol 74 (5) ◽  
pp. 731-742 ◽  
Author(s):  
A. Cole ◽  
W. K. Sinclair ◽  
G. H. Fletcher ◽  
G. C. Johnson
Keyword(s):  
Short Treatment ◽  
Cesium 137

scholarly journals Reducing the Burden of Care: Multidisciplinary Management of Late-Manifested Crouzon Syndrome—A Case Report

Children ◽  
2021 ◽  
Vol 8 (12) ◽  
pp. 1122
Author(s):  
Sarah Achterrath ◽  
Teresa Kruse ◽  
Julia Neuschulz ◽  
Isabelle Graf ◽  
Joachim Zöller ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Psychosocial Development ◽  
Young Patients ◽  
Crouzon Syndrome ◽  
Burden Of Care ◽  
Short Treatment ◽  
Related Quality ◽  
Health Related

The therapy of patients with Crouzon syndrome involves a multidisciplinary team. In most cases, this therapy is extensive, time-consuming, and exhausting for the patient. This case report illustrates a temporally coordinated therapy plan that succeeds in reducing the burden of care. Showing typical extraoral characteristics of Crouzon syndrome, the patient had a frontal and left-sided crossbite, and impaction of the maxillary canines. Multidisciplinary therapy included the extraction of multiple teeth, midface distraction at Le Fort III level, and alignment of the impacted teeth. Before starting, during, and after completion of the treatment, the patient’s oral health-related quality of life was assessed using COHIP-19. The combination of different treatment steps significantly reduced the duration of therapy. The therapy improved not only the patient’s oro- and craniofacial function, but also the patient’s facial appearance in a short treatment period. The patient’s quality of life improved considerably during this time. In the treatment of severe craniofacial anomalies, the highest priority should be given to keeping the burden of care low. All measures should encourage young patients’ appropriate psychosocial development despite extensive therapies, ensuring at the same time medically satisfactory treatment results.

scholarly journals Disputes and their Resolution in the Electronic Communications Market

2016 ◽  
Vol 1 (1) ◽  
pp. 69
Author(s):  
Jonida Gjika
Keyword(s):  
Management Strategies ◽  
Legal Framework ◽  
Fundamental Aspect ◽  
Special Importance ◽  
Electronic Communications ◽  
Short Treatment ◽  
Effective Competition ◽  
Regulatory Policies ◽  
Legal Remedies ◽  
Eu Directives

This short treatment introduces the concept of potential disputes in the electronic communications market, their typology and the background in which exist premises to arise desputes in this market. Broadly represents the forecast of domestic regulatory and legal framework for the treatment of desputes existing in this market, approximation of legislation with EU directives, ways to resolve disputes arising in the potential levels of the market in which those disputes arise. As a summary is treated the concept of internal market/markets structure as domestic part of the electronic communications market, identifying the importance of "treatment" of state and regulatory policies, and their impact on the design, planning and management strategies of the market players. The case of Albania is breafly treated regarding to the aspects referred in topic, closely linked with desputes and their treatment, paying a special importance administrative settlement in procedural terms. Identification of regulatory effect, as potential to be measured and compared with analog markets, and services offered in these markets with other countries, regional, of EU, or wider and mainly in the aspect from they derive, which highly propable are connected to services offered - their tariff - quality products / services. Briefly on the importance of effective competition and its impact on the number of disputes arising in such a market, considering liberalization as factor of market as fundamental aspect in the development of the market, increasing the number of providers of products / services and legal remedies forecast with specific criteria that maximize protection of users of products / services offered.

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