What It Is Like to Be an Intentional System 1

2017 ◽  
pp. 109-116
Keyword(s):  
System 1 ◽  
Author(s):  
Randy Moore

Previous work has indicated that the graft incompatihility between Sedrmi telephoides and Solanum pennellil involves cell necrosis that results In a thick layer of collapsed cells at the graft Interface. This necrotic layer insulates the stock from the scion, which results in abscission of the Sedum scion after 4-6 weeks due to desiccation and starvation. Thus, cell autolysis (which is restricted to Sedum) characterizes the Incompatibility response in this system (1). In order to elucidate the events that lead to cell autolysis, and thus better understand the cellular site and mode of action of cellular incompatibility, the appearance and fate of the hydrolytlc enzyme acid phosphatase (AP) was followed in both the compatible Sedum autograft and the incompatible Sedum/Solanum heterograft. Acid phosphatase was localized by a modified Gomori-type reaction; positive (i.e., including NaF inhibitor) and negative (lacking substrate) controls showed no enzymatic precipitate. Following an initial association with the endoplasmic reticulum (ER) and dictyosomes at 6-10 hours after grafting, AP activity in the compatible Sedum autograft is associated primarily with the plasmalemma (Fig. 1). By 18-24 hours after grafting, the AP activity is restricted to the tono-plast and vacuole (Fig. 2). This strict compartmentation and absence of enzyme from the cytosol is maintained throughout the development of the compatible graft. While AP activity in the incompatible Sedum/Solanum heterograft is Initially similar to the compatible Sedum autograft (i.e., initially found on the ER and dictyosomes), there is a marked difference in enzyme localization in the two graft partners as the incompatibility response develops. As in the compatible autograft, Solanum cells at the graft interface show an Increase in AP activity that Is restricted to the vacuole and tonoplast, with little or no enzyme activity in the cytosol (Fig. 3). In comparable Sedum cells, however, there is a dramatic Increase In AP activity in the cytosol (Fig. h); this cytosollc AP activity is associated with thin fibril-like structures (Fig. 5) measuring approximately 60 A in diameter. This high cytoplasmic AP activity In Sedum cells results in cell autolysis, death, and eventual cell collapse to form the characteristic necrotic layer separating the two graft partners.


2017 ◽  
pp. 29-38 ◽  
Author(s):  
E. P. Fisenko ◽  
J. P. Sich ◽  
N. N. Vetsheva

Objective:a comparative “blind” assessment of the thyroid nodules identified by ultrasound, according to the TI-RADS scale in various modifications.Materials and methods.Retrospective analysis of 149 echograms  of thyroid nodules by three independent experts was performed (the  experience of ultrasound of thyroid ultrasound for more than 7 years).Results. In solid nodules, high-specific large (more than 94%) and  small (more than 90%) ultrasound signs of thyroid cancer have been identified. The nodes are stratified according to the TI-RADS system: 1 – in the modification J.Y. Kwak et al. (2011), 2 – according to the  proposed system, taking into account small ultrasound signs of  thyroid cancer. High reproducibility of both systems are obtained. In the first system 13.7% of cancer nodes fell into the category of TI- RADS 3 (benign formations), in the second system only 5% of  cancers fell into the category of TI-RADS 3, which is important for  biopsy selection. The sensitivity of the first system was TI-RADS  82.05%, of the second system – 94.87%.Conclusions.Classification of TI-RADS can be used to interpret the  ultrasound results of thyroid nodules, taking into account both the  main large and small ultrasound signs of cancer. For its validation in  our country, it is necessary to further broad discussion of the proposed TI-RADS system.


1985 ◽  
Vol 50 (8) ◽  
pp. 1642-1647 ◽  
Author(s):  
Štefan Baláž ◽  
Anton Kuchár ◽  
Ernest Šturdík ◽  
Michal Rosenberg ◽  
Ladislav Štibrányi ◽  
...  

The distribution kinetics of 35 2-furylethylene derivatives in two-phase system 1-octanol-water was investigated. The transport rate parameters in direction water-1-octanol (l1) and backwards (l2) are partition coefficient P = l1/l2 dependent according to equations l1 = logP - log(βP + 1) + const., l2 = -log(βP + 1) + const., const. = -5.600, β = 0.261. Importance of this finding for assesment of distribution of compounds under investigation in biosystems and also the suitability of the presented method for determination of partition coefficients are discussed.


1979 ◽  
Vol 34 (11) ◽  
pp. 1573-1575 ◽  
Author(s):  
Klaus Beelitz ◽  
Klaus Praefcke ◽  
Salo Gronowitz

Abstract UV irradiation of S-(3′-thienyl)2-chloro-thionicotinate (1) in benzene solution leads via dehydrohalogenation and cy clization in competition to α-cleavage to formation of thio-lactone 2 besides aldehyde 3 and disulphide 4. 2 contains a new heterocyclic ring system which has been confirmed by spectroscopic methods.


Appetite ◽  
2021 ◽  
Vol 160 ◽  
pp. 105116 ◽  
Author(s):  
Stephanie S.A.H. Blom ◽  
Marleen Gillebaart ◽  
Femke De Boer ◽  
Nynke van der Laan ◽  
Denise T.D. De Ridder

Animals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 264
Author(s):  
Kathryn E. Ritz ◽  
Bradley J. Heins ◽  
Roger D. Moon ◽  
Craig C. Sheaffer ◽  
Sharon L. Weyers

Organic dairy cows were used to evaluate the effect of two organic pasture production systems (temperate grass species and warm-season annual grasses and cool-season annuals compared with temperate grasses only) across two grazing seasons (May to October of 2014 and 2015) on milk production, milk components (fat, protein, milk urea nitrogen (MUN), somatic cell score (SCS)), body weight, body condition score (BCS), and activity and rumination (min/day). Cows were assigned to two pasture systems across the grazing season at an organic research dairy in Morris, Minnesota. Pasture System 1 was cool-season perennials (CSP) and Pasture System 2 was a combination of System 1 and warm-season grasses and cool-season annuals. System 1 and System 2 cows had similar milk production (14.7 and 14.8 kg d−1), fat percentage (3.92% vs. 3.80%), protein percentage (3.21% vs. 3.17%), MUN (12.5 and 11.5 mg dL−1), and SCS (4.05 and 4.07), respectively. Cows in System 1 had greater daily rumination (530 min/day) compared to cows in System 2 (470 min/day). In summary, warm-season annual grasses may be incorporated into grazing systems for pastured dairy cattle.


2021 ◽  
Author(s):  
Lidia Rosado Piquer ◽  
Jan Dreiser ◽  
E. Carolina Sañudo

The heterometallic 3d-4f SMM [Co4Dy(OH)2(SALOH)5(chp)4(MeCN)(H2O)2] (1) has been deposited onto iron oxide nanoparticles (NP) with an oleate self-assembled monolayer (SAM) as surfactant. The hybrid molecular-inorganic system 1-NP has been thoroughly...


2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 25-26
Author(s):  
Nicholas W Dias ◽  
Claire L Timlin ◽  
Stefania Pancini ◽  
Nicholas W Dias ◽  
Zackary Seekford ◽  
...  

Abstract The objective of this study was to evaluate changes in vaginal pH of beef cows enrolled in a 7-d CO-Synch+controlled internal drug release (CIDR) protocol and its effects on pregnancy. A total of 46 multiparous beef cows with no signs of vaginitis were enrolled. Individual vaginal flushes were collected from cows on D0, D7 and D10. Individual flushes were immediately analyzed for pH with a portable pH meter. As evidence of vaginitis, a CIDR score was determined at CIDR removal (D7), following a 1 to 4 scoring system: 1 = clean, no secretion; 2 = clean, clear secretion; 3 = purulent secretion; 4 = purulent secretion and blood. Pregnancy status was determined by rectal ultrasonography approximately 40 days after TAI. No cows had CIDR scores of 1 or 4, 19.6% of cows had a score of 2 and 80.4% a score of 3. Vaginal pH increased from D0 (6.88±0.007) to D7 (7.32±0.047), regardless of CIDR score (P < 0.001). Cows with a CIDR score 2 had greater pH on D7 (7.35±0.084) than on D0 (6.90± 0.14; P = 0.001), and pH on D10 was intermediate (7.14±0.14; P = 0.14). Cows with CIDR score 3 had reduced pH on D10 (7.09±0.07) when compared to D7 (7.29±0.04; P = 0.003), but greater pH on D10 than on D0 (6.87±0.07; P = 0.007). There was a pregnancy by day interaction for pH values (P = 0.046). Pregnant cows had greater vaginal pH in comparison with non-pregnant cows on D0 (6.99±0.081 and 6.68±0.09, respectively; P = 0.01) and D10 (7.26±0.08 and 6.89±0.09, respectively; P = 0.006), but not on D7 (7.34±0.05 and 7.27±0.06, respectively; P = 0.38). Non-pregnant cows had reduced vaginal pH on D10 in comparison to D7 (6.89±0.09 and 7.27±0.06, respectively; P < 0.001), whereas pregnant cows had similar vaginal pH on D10 and D7 (7.26±0.08 and 7.34±0.05, respectively; P = 0.35). We conclude that CIDR increases vaginal pH overtime and greater pH at TAI is beneficial to fertility.


Sign in / Sign up

Export Citation Format

Share Document