scholarly journals AVALIAÇÃO DA PREVALÊNCIA DE ENTEROPARASITOSES EM CRIANÇAS E ADOLESCENTES ATENDIDOS POR UMA AÇÃO SOCIAL NA CIDADE DE SOROCABA – SP

2021 ◽  
Vol 58 (1) ◽  
pp. eUJ4004
Author(s):  
Izadora Renosto ◽  
◽  
Isabella Kurokawa Sanches ◽  
Larissa Guerino Ferla ◽  
Gustavo Henrique Oliveira da Rocha ◽  
...  
Keyword(s):  
Social Services ◽  
Giardia Lamblia ◽  
Scientific Literature ◽  
Eating Habits ◽  
Parasitic Diseases ◽  
Major Health ◽  
Stool Samples ◽  
Close Relatives ◽  
The City ◽  
Major Health Issue

Enteric parasitic diseases pose a major health issue in Brazil. Children living in poorer areas are particularly more likely to become infected with parasites, as inadequate living conditions favor dissemination of such parasites. This work aimed to determine prevalence of parasites in stool samples obtained from children and teenagers supported by social services in the city of Sorocaba – São Paulo. Three stool samples were collected from each child enrolled in the study; samples were subjected to spontaneous sedimentation and then analyzed under a microscope. Children (or any close relatives for them responsible) answered a form regarding education level, eating habits, having had previous enteric parasitic diseases and presence of symptoms associated with such diseases. Prevalence of enteric parasitic diseases was 30%, these being caused by Entamoeba coli (20%), Giardia lamblia (2.5%), Iodamoeba butschlii (2.5%) and Urbanorum spp. (5%); no helminths were identified. While there is a likely contamination of children and teenagers via drinking water and food, prevalence of enteric parasitic diseases was lower when compared to other studies found in scientific literature, most likely due to local families being supported by social services.

scholarly journals Intestinal parasites in school food handlers in the city of Uberlândia, Minas Gerais, Brazil

1995 ◽  
Vol 37 (3) ◽  
pp. 191-196 ◽  
Author(s):  
Julia Maria Costa-Cruz ◽  
Margareth Leitão Gennari Cardoso ◽  
Daldy Endo Marques
Keyword(s):  
Giardia Lamblia ◽  
Intestinal Parasites ◽  
Specific Treatment ◽  
Strongyloides Stercoralis ◽  
Minas Gerais ◽  
Food Handlers ◽  
School Food ◽  
Public Elementary Schools ◽  
Stool Samples ◽  
The City

In order to verify the presence of intestinal parasites in food handlers, stool samples were collected from 104 cooks and their helpers that were working in food preparation in 20 public elementary schools, in various areas of the city of Uberlândia, Minas Gerais, Brazil. The samples were collected during the months of November and December, 1988, in plastic flasks containing a 10% formaldehyde solution and processed by the Hoffmann, Pons & Janer method. The sediment was examined using triplicate slides. All individuals were females aged between 24 to 69 years. Intestinal parasites were found in 85.0% of the studied schools and 47.1% of the studied food handlers (cooks and helpers) were found to be positive. Among the 49 infected food handlers, 32 (65.3%) carried a single parasite and 17 (34.7%) carried two parasites. The following intestinal parasites were found: Giardia lamblia (21.1%), Entamoeba coli (21.1%), hookworms (9.6%), Ascaris lumbricoides (5.8%), Entamoeba histolytica (2.9%), Hymenolepis nana (1.9%), Strongyloides stercoralis (1.0%). These data emphasize the need for a rigid semi-annual control in all school food handlers, including diagnosis, specific treatment and orientation about the mechanisms of transmission of the intestinal parasites.

An Epidemiological, Diagnostic and Therapeutic Study of Giardia lamblia in Anbar Province – Iraq

2019 ◽  
Vol 9 (01) ◽  
pp. 39-45
Author(s):  
Suad Shallal Shahatha
Keyword(s):  
Teaching Hospital ◽  
Rural Areas ◽  
Giardia Lamblia ◽  
Urban Areas ◽  
Culture Media ◽  
Age Groups ◽  
Stool Samples ◽  
Women And Children ◽  
Teucrium Polium L ◽  
Therapeutic Study

This study was carried out to investigate the epidemiology of Giardia lamblia parasites in patients who visited some of the hospitals in Anbar province, which included (Fallujah Teaching Hospital, Ramadi Teaching Hospital, Ramadi Teaching Hospital for Women and Children and Hit Hospital) during by examining 864 stool samples in a direct examination method, The results revealed the infection rate was 41.7 % and the percentage of infection among males 47.8% is higher than that of females 35.4% with significant differences (p≤0.05). The age groups (1-9) years recorded the highest rates 55.4% and the lowest rate 13.6% in the age group (40-49) years. The highest rate of infection was 62.5% during the month of June, while the month of October was the lowest rate 5% and significant differences. The incidence rate in rural areas was 50.6% higher than in the urban areas 32.5%. The study also included the effect of Teucrium polium L. on the parasite in the culture media HSP-1, the concentrations of 0.5-3 mg / mL significantly affected Giardia, it was noted whenever the greater the concentration, the greater the effect during different treatment periods (1-4) days, as the highest concentration 3 mg/ml killed all Giardia parasites on the fourth day of treatment.

Recent Advances in the Development of Broad-Spectrum Antiprotozoal Agents

2020 ◽  
Vol 27 ◽  
Author(s):  
Antonio Moreno-Herrera ◽  
Sandra Cortez-Maya ◽  
Virgilio Bocanegra-Garcia ◽  
Bimal Krishna Banik ◽  
Gildardo Rivera
Keyword(s):  
Giardia Lamblia ◽  
Heterocyclic Compounds ◽  
Trichomonas Vaginalis ◽  
Mechanisms Of Action ◽  
Parasitic Infections ◽  
Parasitic Diseases ◽  
Pharmacological Treatments ◽  
Preclinical Development ◽  
Leishmania Spp ◽  
Effective Drugs

: Infections caused by Trypanosoma brucei, Trypanosoma cruzi, Leishmania spp., Entamoeba histolytica, Giardia lamblia, Plasmodium spp., and Trichomonas vaginalis, are part of a large list of human parasitic diseases. Together, they cause more than 500 million infections per year. These protozoa parasites affect both low- and high-income countries and their pharmacological treatment is limited. Therefore, new and more effective drugs in preclinical development could improve overall therapy for parasitic infections even when their mechanisms of action are unknown. In this review, a number of heterocyclic compounds (diamidine, guanidine, quinoline, benzimidazole, thiazole, diazanaphthalene, and their derivatives) reported as antiprotozoal agents are discussed as options for developing new pharmacological treatments for parasitic diseases.

Exciting Potential of Nanoparticlized Lipidic System for Effective Treatment of Breast Cancer and Clinical Updates: A Translational Prospective

2020 ◽  
Vol 26 (11) ◽  
pp. 1191-1205 ◽  
Author(s):  
Ranjit K. Harwansh ◽  
Shiv Bahadur ◽  
Rohitas Deshmukh ◽  
Md. A. Rahman
Keyword(s):  
Breast Cancer ◽  
Clinical Trials ◽  
Major Health ◽  
Traditional Drug ◽  
Present Context ◽  
Exciting Potential ◽  
Transcriptional Changes ◽  
Deadly Disease ◽  
Targeted Approach ◽  
Major Health Issue

: Breast cancer (BC) is a multifactorial disease and becoming a major health issue in women throughout the globe. BC is a malignant type of cancer which results from transcriptional changes in proteins and genes. Besides the availability of modern medicines and detection tools, BC has become a topmost deadly disease and its cure still remains challenging. Nanotechnology based approaches are being employed for the diagnosis and treatment of BC at clinical stages. Nanosystems have a significant role in the study of the interaction of malignant cells with their microenvironment through receptor-based targeted approach. Nowadays, lipid-based nanocarriers are being popularized in the domain of pharmaceutical and medical biology for cancer therapy. Lipidic nanoparticlized systems (LNPs) have proven to have high loading efficiency, less toxicity, improved therapeutic efficacy, enhanced bioavailability and stability of the bioactive compounds compared to traditional drug delivery systems. In the present context, several LNPs based formulations have been undertaken in various phases of clinical trials in different countries. This review highlights the importance of chemotherapeutics based lipidic nanocarriers and their anticipated use for the treatment of BC. Furthermore, the clinical trials and future prospective of LNPs have been widely elaborated.

Conquering the Public Space

2018 ◽  
Author(s):  
Samuel Llano
Keyword(s):  
Public Space ◽  
Social Services ◽  
Social Groups ◽  
Public Image ◽  
Working Classes ◽  
The Public ◽  
San Bernardino ◽  
The City

This chapter presents an account of the San Bernardino band as the public facade of that workhouse. The image of children who had been picked up from the streets, disciplined, and taught to play an instrument as they marched across the city in uniform helped broadcast the message that the municipal institutions of social aid were contributing to the regeneration of society. This image contrasted with the regime of discipline and punishment inside the workhouse and thus helped to legitimize the workhouse’s public image. The privatization of social aid from the 1850s meant that the San Bernardino band engaged with a growing range of institutions and social groups and carried out an equally broad range of social services. It was thus able to serve as the extension through which Madrid’s authorities could gain greater intimacy with certain population sectors, particularly with the working classes.

scholarly journals The Role of Lifestyle, Eating Habits and Social Environment in the Prevention and Treatment of Type 2 Diabetes and Hypertension

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1460
Author(s):  
Kalliopi Karatzi ◽  
Yannis Manios
Keyword(s):  
Type 2 Diabetes ◽  
Social Environment ◽  
Eating Habits ◽  
Health Problems ◽  
Major Health ◽  
The Past ◽  
Prevention And Treatment

Type 2 diabetes (T2DM) and hypertension are major health problems, with an undisputed growth burden in the past decades [...]

Gait Disorder among Elderly People, Psychomotor Disadaptation Syndrome: Post-Fall Syndrome, Risk Factors and Follow-Up – A Cohort Study of 70 Patients

Gerontology ◽  
2020 ◽  
pp. 1-8
Author(s):  
Maxence Meyer ◽  
Florentin Constancias ◽  
Thomas Vogel ◽  
Georges Kaltenbach ◽  
Elise Schmitt
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Fear Of Falling ◽  
Functional Mobility ◽  
General Physician ◽  
Major Health ◽  
Mobility Assessment ◽  
Control Study ◽  
Major Health Issue

<b><i>Introduction:</i></b> Falls among older people are a major health issue and the first cause of accidental death after 75 years of age. Post-fall syndrome (PFS) is commonly known and yet poorly studied. <b><i>Objective:</i></b> Identify risk factors for PFS and do a follow-up 1 year later. <b><i>Methods:</i></b> We included all patients over 70 years of age hospitalized after suffering a fall in a case-control study, and then followed them in a cohort study. PFS was retained in case of functional mobility decline (transferring, walking) occurring following a fall in the absence of an acute neurological, orthopedic or rheumatic pathology directly responsible for the decline. The data initially collected were: clinical (anamnestic, emergency and departmental/ward evolution, medical history, lifestyle, treatments, clinical examination items); and imaging if the patient had been subjected to brain imaging in the last 3 years prior to inclusion. Regarding the follow-up at 1 year, we collected from the general physician the occurrence and the characteristics of new falls, functional mobility assessment, hospitalization and death. <b><i>Results:</i></b> Inclusion took place from March 29, 2016 to June 7, 2016 and follow-up until June 30, 2017. We included 70 patients. A total of 29 patients exhibited a PFS (41.4 %). Risk factors for PFS included age, walking disorder prior to the fall, the use of a walking aid prior to the fall, no unaccompanied outdoor walk in the week before the fall, visual impairment making close reading impossible, stiffness in ankle dorsiflexion, grip strength and the fear of falling. Among patients with PFS, 52.9% could still perform a transfer at 1 year and 64.7% could still walk against 80.7% and 85.2%, respectively, for patients without PFS. <b><i>Conclusion:</i></b> The study showed the existence of body functions/structure impairments and activity limitations prior to the fall among patients exhibiting a PFS. This suggests the existence of a pre-fall syndrome, i.e., a psychomotor disadaptation syndrome existing prior to the fall. Among the 8 risk factors, fear of falling, vision impairment and muscle strength could be targeted for improvement. The diagnosis of PFS could be a marker of loss of functional mobility at 1 year.

scholarly journals Zinc and Sepsis

Nutrients ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 976 ◽  
Author(s):  
Wiebke Alker ◽  
Hajo Haase
Keyword(s):  
Defense Mechanism ◽  
Acute Phase Proteins ◽  
Innate Immune ◽  
Zinc Homeostasis ◽  
Major Health ◽  
Nutritional Immunity ◽  
Life Threatening ◽  
Zinc Concentrations ◽  
Severity Of The Disease ◽  
Major Health Issue

Sepsis, defined as a “life-threatening organ dysfunction caused by a dysregulated host-response to infection” is a major health issue worldwide and still lacks a fully elucidated pathobiology and uniform diagnostic tests. The trace element zinc is known to be crucial to ensure an appropriate immune response. During sepsis a redistribution of zinc from serum into the liver has been observed and several studies imply a correlation between zinc and sepsis outcome. Therefore the alterations of zinc concentrations in different tissues might serve as one part of the host’s defense mechanism against pathogens during sepsis by diverse mechanisms. It has been suggested that zinc is involved in nutritional immunity, acts as a hepatoprotective agent, or a differentiation signal for innate immune cells, or supports the synthesis of acute phase proteins. Further knowledge about these events could help in the evaluation of how zinc could be optimally applied to improve treatment of septic patients. Moreover, the changes in zinc homeostasis are substantial and correlate with the severity of the disease, suggesting that zinc might also be useful as a diagnostic marker for evaluating the severity and predicting the outcome of sepsis.

Prevalence of Entamoeba histolytica and Giardia lamblia in Children in Kadhmiyah Hospital

2012 ◽  
Vol 36 (1) ◽  
pp. 1-5
Author(s):  
Amjed Qays Ibrahim
Keyword(s):  
Entamoeba Histolytica ◽  
Giardia Lamblia ◽  
Age Group ◽  
Significant Relation ◽  
Female Ratio ◽  
Male Ratio ◽  
Infectivity Rate ◽  
Stool Samples

In this study we collect 1520 stool samples during the period from September to December 2010 from children whom their ages between 1 month - 12 years. The results showed that the total infection of Entamoeba histolytica was 9.80% , and Giardia lamblia was 1.77%. And the male ratio that infected with Entamoeba histolytica was 9.83% , while the female ratio was 9.74%; and the male infected with Giardia lamblia was 1.51% , while the female ratio was 2.18%. The result showed that the high average of infection with Entamoeba histolytica and Giardia lamblia in age group from 1 month to 2 years. And there is no significance difference between gender and infectivity rate of Entamoeba histolytica and Giardia lamblia under P≤0.05. Also it showed that there were significant relation between Age group and infectivity rate of Entamoeba histolytica and Giardia lamblia.

scholarly journals Mercury and methylmercury concentration assessment in children's hair from Manaus, Amazonas state, Brazil

2012 ◽  
Vol 42 (2) ◽  
pp. 279-286 ◽  
Author(s):  
Luciana A. Farias ◽  
Déborah I. T. Fávaro ◽  
Artemiza Pessoa ◽  
Jaime P. L. Aguiar ◽  
Lúcia K. O. Yuyama
Keyword(s):  
Eating Habits ◽  
Adult Population ◽  
Published Data ◽  
Future Studies ◽  
Cultural Aspects ◽  
Hair Samples ◽  
Total Hg ◽  
Amazonas State ◽  
The City ◽  
Concentration Assessment

The present study evaluated Hg and MeHg content in hair samples of 201 children 2 to 7 years old, living in six neighborhoods of the city of Manaus, Amazonas State, Brazil. In general, the total Hg and MeHg median ranges in hair were similar (0.91 to 1.71 mg kg-1) except for the São Jose neighborhood, which was lower (0.16 mg kg-1). De spite the fact that the Manaus population consumes fish as part of the normal dietary intake, the Hg hair levels were below the level for an adult population not exposed to mercury (2.0 mg kg-1). These data were compared to demographic, socioeconomic information and eating habits of the families that took part in the study. The results were also compared to other published data from the Amazon region, other regions of Brazil and other countries. Future studies to set Hg and MeHg levels in hair of children in Brazil should take into account and assess the diversity of the country, mainly in terms of eating habits, socio-economic and cultural aspects.

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