Ethnopharmacological Studies of Medicinal plants Used by Ethnic Groups in Bardsir Region, Kerman Province

Ethnobotanical studies try to gather indigenous cultures plant knowledge from different regions and tribes all over the world. This study aimed at obtaining, documenting and analyzing medicinal plants used by some ethnic groups in Bardsir region, Kerman province, Iran. Data collection was done through face-to-face interviews, and finally, 120 questionnaires were filled out. Based on the local knowledge, the data collection was analyzed using quantitative values including family importance value (FIV), relative frequency of citation (RFC), fidelity level (FL), use-value index (UV), and factor of informant consensus (FIC). In this study, 47 medicinal plants were recorded belonging to 22 families. The results expressed the highest FIV belonged to Lamiaceae (57%) family. The hemicryptophytes (49%) were also regarded as the most common life forms of the used species. In the current study, the highest RFCs and UV indices belonged to Urtica urens L. 0.21, and 0.39, respectively. Achillea santolinoides subsp. wilhelmsii (K.Koch) Greuter, and Teucrium polium L. had the maximum percentage of FL for treating digestive system disorders. In the present study, the highest indices belonged to U. urens, A. santolinoides subsp. wilhelmsii and T. polium; thus, it is recommended conducting further in vitro and in vivo pharmacological studies on the mentioned species.

Elimination of Congo Red Dye from Industrial Wastewater Using Teucrium polium L. as a Low-Cost Local Adsorbent

A novel adsorbent prepared from the leaf powder of Teucrium polium L. (TPLLP) was characterized and its ability for adsorption of Cong red (CR) was inspected. Influences of CR concentration, adsorbent dosage, time of agitation, pH of solution, and temperature on the performance of this adsorption were also examined. Three models of kinetic along with three different isotherm models were applied for analyzing the empirical data of this adsorption. Additionally, the thermodynamic constants of were decided. The surface area, pore volume, pore size, and pHZPC of Zn/Cu-TPLLP were found to be 2.6436 m2.g-1, 0.013317 cm3.g-1, 527.393 Å, and 8.8, respectively. The achieved outcomes indicate the positive influence of temperature, concentration of CR in the range of 20 to 900 mg/L, adsorbent mass in the range of 0.005 to 0.02 g, time of adsorption from 0 to 120 min, and pH from 5.5 to 8.5. Models of the 2nd order with R 2 ≥ 0.995 and Langmuir with R 2 ≥ 0.990 were the best among the other kinetic and isotherm models applied in this research. Moreover, superior capacities of 526.32, 666.67, and 909.09 (mg.g-1) were stemmed at 27, 42, and 57°C, respectively. The outcomes of the thermodynamic evidenced that this adsorption is spontaneous and a heat absorber.

Phytochemical Screening, Antibacterial, Antifungal, Antiviral, Cytotoxic, and Anti-Quorum-Sensing Properties of Teucrium polium L. Aerial Parts Methanolic Extract

The chemical profile of Teucrium polium L. (T. polium) methanolic extract was tested using liquid chromatography coupled with high resolution mass spectrometry (HR-LCMS). Disc diffusion and microdilution assays were used for the antimicrobial activities. Coxsackievirus B-3 (CVB3) and Herpes simplex virus type 2 (HSV-2) were used for the antiviral activities. Chromobacterium violaceum (ATCC 12472 and CV026) and Pseudomonas aeruginosa PAO1 were used as starter strains for the anti-quorum sensing tests. Isoprenoids are the main class of compounds identified, and 13R-hydroxy-9E,11Z-octadecadienoic acid, valtratum, rhoifolin, sericetin diacetate, and dihydrosamidin were the dominant phytoconstituents. The highest mean diameter of growth inhibition zone was recorded for Acinetobacter baumannii (19.33 ± 1.15 mm). The minimal inhibitory concentrations were ranging from 6.25 to 25 mg/mL for bacterial strains, and from 6.25 to 25 mg/mL for Candida species. The 50% cytotoxic concentration on VERO (African Green Monkey Kidney) cell lines was estimated at 209 µg/mL. No antiviral activity was recorded. Additionally, T. polium extract was able to inhibit P. aeruginosa PAO1 motility in a concentration-dependent manner. However, the tested extract was able to inhibit 23.66% of the swarming and 35.25% of swimming capacities of PAO1 at 100 µg/mL. These results highlighted the role of germander as a potent antimicrobial agent that can interfere with the virulence factors controlled by the quorum-sensing systems.