scholarly journals Issues of patient safety in the context of preventing medical errors (analytical review)

2020 ◽  
Vol 64 (4) ◽  
pp. 209-213
Author(s):  
Davlatmurod A. Olimov ◽  
Gafur M. Khodzhamurodov ◽  
Rustam A. Tursunov
Keyword(s):  
Patient Safety ◽  
Medical Care ◽  
Medical Errors ◽  
Target Area ◽  
Quality And Safety ◽  
Clinical Safety ◽  
Analytical Review ◽  
Clinically Significant ◽  
Preventable Harm ◽  
The Individual

Introduction. Patient safety is the absence of preventable harm to the patient in the course of medical care and the reduction of the risk of unnecessary harm associated with medical care to an acceptable minimum. Over the past two decades, the problem of patient safety has become the object and target area of public health for specific efforts to improve it. The study aims to analyze modern scientific literature to consider problems related to clinical safety, the global burden of harming patients. Material and methods. In the context of studying the problem, the results of modern research were used to identify the causes of medical errors and to find ways to prevent them. Results. The desire to improve the level of safety and the quality of medical care is growing in the world. Consequently, significant measures to evaluate the safety of medical care and its quality will be of paramount importance. To date, there is no gold standard or established array of quality indices (QI) for measuring the quality and safety of medical care. However, many indices have been developed, and some have even been tested to measure specific aspects of patient quality and safety. Such studies are in demand to achieve a clinically significant reduction in the incidence of medical errors. Conclusion. Despite the growing recognition of the role of human medical error in medicine, to prevent or mitigate their consequences requires the search for adequate ways both at the individual and systemic levels.

scholarly journals How ISO-15189 laboratory accreditation assures patient safety? / Kako ISO-15189 akreditacija laboratorija osigurava bezbednost pacijenta?

2012 ◽  
Vol 31 (4) ◽  
pp. 271-280 ◽  
Author(s):  
Mustafa Serteser ◽  
Abdurrahman Coskun ◽  
Tamer C. Inal ◽  
Ibrahim Unsal
Keyword(s):  
Patient Safety ◽  
Medical Errors ◽  
Interdisciplinary Approach ◽  
Professional Associations ◽  
Shared Responsibility ◽  
Medical Laboratory ◽  
Iso 15189 ◽  
Outcomes Of Care ◽  
Laboratory Services ◽  
The Individual

Summary Healthcare is a complex profession involving the state-of-art technology and sometimes leading to unintentional harm. Many factors contribute to the occurrence of medical errors. Patient safety is one of the most serious global health issues and defined as the absence of preventable harm to a patient during any process of medical care. The frequency of medical errors is higher than expected. It has been concluded that the majority of medical errors are not because of the individual attitudes but mainly caused by faulty systems or processes leading the staff to make mistakes or fail to prevent them. Patient safety is a shared responsibility comprised of many stakeholders such as society, patients, nurses, educators, administrators, researchers, physicians, government and legislative bodies, professional associations and accrediting agencies. Medical laboratory services are essential to patient care and need to be available to meet the needs of both patients and caregivers. ISO- 15189:2007 Medical Laboratories-Particular requirements for quality and competence, an internationally recognized standard containing requirements necessary for diagnostic laboratories to demonstrate their competence to deliver reliable laboratory services. It applies quality system requirements to the clinical laboratories with a strong focus on responsiveness to the needs of patients and clinicians. Applying the performance improvement strategies focusing on different phases in total testing process will significantly reduce the errors and therefore will improve the patient safety. In this way, laboratory professionals contribute to improvement of safety and outcomes of care by working in interdisciplinary approach manner.

scholarly journals Socio-economic aspects of medical errors and their consequences in medical organizations

2019 ◽  
Vol 10 (1) ◽  
pp. 99-113 ◽  
Author(s):  
O. L. Zadvornaya ◽  
Yu. E. Voskanyan ◽  
I. B. Shikina ◽  
K. N. Borisov
Keyword(s):  
Public Health ◽  
Patient Safety ◽  
Adverse Events ◽  
Medical Care ◽  
Medical Errors ◽  
Quality Management System ◽  
The State ◽  
Risk Indicators ◽  
Economic Costs ◽  
Published Evidence

Medical errors and adverse events are a global problem of strategic importance, accompanied by economic costs that impose a burden on the health care system, the country's economy and society as a whole. The article presents the results of a review of world experience in developing approaches to assessing the safety of medical care in medical organizations, systematization and analysis of factors affecting the patient safety.Purpose: the purpose of the article is to study and assess the risks associated with medical errors and adverse events in the activities of medical organizations that affect the patient safety in order to reduce the loss of public health, improve the system of identification and monitoring of risk indicators that affect the safety of medical care.Methods: the method of rapid assessment and content analysis of published evidence, including who experience in safety of medical care, was used to highlight the issue. The methodology of functional benchmarking, which included the collection and analysis of the necessary information, the choice of individual functions, processes, methods of work of medical organizations working in similar conditions, was used in the study.Results: the approaches allowing to predict occurrence and development of risks in ensuring safety of medical care, reduction of losses of public health and social and economic costs of the state are considered and offered.Conclusions and Relevance: the materials presented in the article show that safety is a fundamental principle of providing medical services to patients and a critical component of the quality management system of medical care. To reduce the loss of public health, direct and indirect socio-economic costs of the state, comprehensive efforts are needed to reduce the risks that threaten the patient safety and improve the activities of medical organizations. 

Patient Scheduling — (Bibliography)

1977 ◽  
Vol 16 (02) ◽  
pp. 112-115 ◽  
Author(s):  
C. O. Köhler ◽  
G. Wagner ◽  
U. Wolber
Keyword(s):  
Information Processing ◽  
Medical Care ◽  
Medical Informatics ◽  
Relevant Literature ◽  
Patient Scheduling ◽  
Individual Scientist ◽  
Set Up ◽  
The Individual ◽  
New Literature ◽  
Current Systems

The entire field of information processing in medicine is today already spread out and branched to such an extent that it is no longer possible to set up a survey on relevant literature as a whole. But even in narrow parts of medical informatics it is hardly possible for the individual scientist to keep up to date with new literature. Strictly defined special bibliographies on certain topics are most helpful.In our days, problems of optimal patient scheduling and exploitation of resources are gaining more and more importance. Scientists are working on the solution of these problems in many places.The bibliography on »Patient Scheduling« presented here contains but a few basic theoretical papers on the problem of waiting queues which are of importance in the area of medical care. Most of the papers cited are concerned with practical approaches to a solution and describe current systems in medicine.In listing the literature, we were assisted by Mrs. Wieland, Mr. Dusberger and Mr. Henn, in data acquisition and computer handling by Mrs. Gieß and Mr. Schlaefer. We wish to thank all those mentioned for their assistance.

The quality and safety of rendering emergency and urgent medical care in hospitals

2019 ◽  
Vol 27 (3) ◽  
Author(s):  
Ivanov I. V. ◽  
◽  
Shvabskii O. R. ◽  
Minulin I. B. ◽  
Shcheblykina A. A. ◽  
...  
Keyword(s):  
Medical Care ◽  
Quality And Safety

System of quality and safety management in medical organization. Modern state

2019 ◽  
Vol 2019 (6) ◽  
pp. 15-23 ◽  
Author(s):  
Игорь Иванов ◽  
Igor' Ivanov
Keyword(s):  
Medical Care ◽  
Internal Control ◽  
Safety Management ◽  
Internal Quality ◽  
Modern State ◽  
Quality And Safety ◽  
Main Attention ◽  
Medical Organization ◽  
Safety Control

The article presents main approaches to provision of quality and safety of medical organization’s activities. The main attention is focused on the issues of implementation of the Suggestions (recommended practice) of Roszdravnadzor on organization of the internal quality and safety control of medical activities, as well as particular points of the Order of June 7, 2019 No. 381n “On Approval of Requirements for organization and conduction internal control of the quality and safety of medical care in hospitals”.

scholarly journals Enterococcus faecalis exploits the human fibrinolytic system to drive excess collagenolysis: implications in gut healing and identification of druggable targets

2020 ◽  
Vol 318 (1) ◽  
pp. G1-G9 ◽  
Author(s):  
Richard A. Jacobson ◽  
Kiedo Wienholts ◽  
Ashley J. Williamson ◽  
Sara Gaines ◽  
Sanjiv Hyoju ◽  
...  
Keyword(s):  
Enterococcus Faecalis ◽  
Healing Process ◽  
Abdominal Sepsis ◽  
Infectious Complications ◽  
Fibrinolytic System ◽  
Clinical Safety ◽  
High Concentrations ◽  
Clinically Significant

Perforations, anastomotic leak, and subsequent intra-abdominal sepsis are among the most common and feared complications of invasive interventions in the colon and remaining intestinal tract. During physiological healing, tissue protease activity is finely orchestrated to maintain the strength and integrity of the submucosa collagen layer in the wound. We (Shogan, BD et al. Sci Trans Med 7: 286ra68, 2015.) have previously demonstrated in both mice and humans that the commensal microbe Enterococcus faecalis selectively colonizes wounded colonic tissues and disrupts the healing process by amplifying collagenolytic matrix-metalloprotease activity toward excessive degradation. Here, we demonstrate for the first time, to our knowledge, a novel collagenolytic virulence mechanism by which E. faecalis is able to bind and locally activate the human fibrinolytic protease plasminogen (PLG), a protein present in high concentrations in healing colonic tissue. E. faecalis-mediated PLG activation leads to supraphysiological collagen degradation; in this study, we demonstrate this concept both in vitro and in vivo. This pathoadaptive response can be mitigated with the PLG inhibitor tranexamic acid (TXA) in a fashion that prevents clinically significant complications in validated murine models of both E. faecalis- and Pseudomonas aeruginosa-mediated colonic perforation. TXA has a proven clinical safety record and is Food and Drug Administration approved for topical application in invasive procedures, albeit for the prevention of bleeding rather than infection. As such, the novel pharmacological effect described in this study may be translatable to clinical trials for the prevention of infectious complications in colonic healing. NEW & NOTEWORTHY This paper presents a novel mechanism for virulence in a commensal gut microbe that exploits the human fibrinolytic system and its principle protease, plasminogen. This mechanism is targetable by safe and effective nonantibiotic small molecules for the prevention of infectious complications in the healing gut.

scholarly journals Practical considerations for creating a strategic and proactive clinical safety and pharmacovigilance organization for the future

2021 ◽  
pp. 1-16
Author(s):  
Magnus Nord ◽  
Magnus Ysander ◽  
Tim Sullivan ◽  
Mayur Patel
Keyword(s):  
Decision Making ◽  
Patient Safety ◽  
Observation Time ◽  
Operating Model ◽  
Clinical Safety ◽  
Patent Expiry ◽  
Multiple Challenges ◽  
Set Up ◽  
Main Components ◽  
Future Business

OBJECTIVE: In 2012, Patient Safety (PS) in AstraZeneca was facing a situation with multiple challenges, scientifically and structurally. To meet these and support AstraZeneca’s ambition to return to growth after years of patent expiry, we undertook a project to fundamentally revisit ways of working to create an organisation set up to provide strategic safety in support of drug project decision-making. METHOD: In this paper, we describe the challenges we faced, the project to deliver changes to respond to them, and the methodology used. The project had two main components: creating a new operating model and simplifying the procedural framework. RESULTS: It was delivered in a focused effort by internal PS resources with cross-functional input. The framework simplification resulted in a 71% reduction in procedural documents and a survey of PS staff revealed an increase in satisfaction of 10%–20% across all scores. CONCLUSIONS: With >3 years of observation time, this project has provided AstraZeneca with a PS organisation able to provide strategic safety, supporting successful portfolio delivery, while ensuring patient safety and maintaining compliance with global pharmacovigilance regulations. It has driven efficiency and set the foundation for continued organisational evolution to meet future business needs in an everchanging environment.

scholarly journals Application of electronic trigger tools to identify targets for improving diagnostic safety

2018 ◽  
Vol 28 (2) ◽  
pp. 151-159 ◽  
Author(s):  
Daniel R Murphy ◽  
Ashley ND Meyer ◽  
Dean F Sittig ◽  
Derek W Meeks ◽  
Eric J Thomas ◽  
...  
Keyword(s):  
Adverse Event ◽  
Patient Safety ◽  
High Risk ◽  
Health Systems ◽  
Language Processing ◽  
Diagnostic Errors ◽  
Diagnostic Process ◽  
Future Research ◽  
Implementation Challenges ◽  
Preventable Harm

Progress in reducing diagnostic errors remains slow partly due to poorly defined methods to identify errors, high-risk situations, and adverse events. Electronic trigger (e-trigger) tools, which mine vast amounts of patient data to identify signals indicative of a likely error or adverse event, offer a promising method to efficiently identify errors. The increasing amounts of longitudinal electronic data and maturing data warehousing techniques and infrastructure offer an unprecedented opportunity to implement new types of e-trigger tools that use algorithms to identify risks and events related to the diagnostic process. We present a knowledge discovery framework, the Safer Dx Trigger Tools Framework, that enables health systems to develop and implement e-trigger tools to identify and measure diagnostic errors using comprehensive electronic health record (EHR) data. Safer Dx e-trigger tools detect potential diagnostic events, allowing health systems to monitor event rates, study contributory factors and identify targets for improving diagnostic safety. In addition to promoting organisational learning, some e-triggers can monitor data prospectively and help identify patients at high-risk for a future adverse event, enabling clinicians, patients or safety personnel to take preventive actions proactively. Successful application of electronic algorithms requires health systems to invest in clinical informaticists, information technology professionals, patient safety professionals and clinicians, all of who work closely together to overcome development and implementation challenges. We outline key future research, including advances in natural language processing and machine learning, needed to improve effectiveness of e-triggers. Integrating diagnostic safety e-triggers in institutional patient safety strategies can accelerate progress in reducing preventable harm from diagnostic errors.

Patient Safety/Quality Improvement Primer, Part III: The Role of Simulation

2021 ◽  
pp. 019459982110133
Author(s):  
Ellen S. Deutsch ◽  
Sonya Malekzadeh ◽  
Cecelia E. Schmalbach
Keyword(s):  
Patient Safety ◽  
Quality Improvement ◽  
Control Charts ◽  
Neck Surgery ◽  
Resident Training ◽  
Statistical Process ◽  
Ensure Patient Safety ◽  
Statistical Process Control Charts ◽  
The Individual ◽  
The Impact

Simulation training has taken a prominent role in otolaryngology–head and neck surgery (OTO-HNS) as a means to ensure patient safety and quality improvement (PS/QI). While it is often equated to resident training, this tool has value in lifelong learning and extends beyond the individual otolaryngologists to include simulation-based learning for teams and health systems processes. Part III of this PS/QI primer provides an overview of simulation in medicine and specific applications within the field of OTO-HNS. The impact of simulation on PS/QI will be presented in an evidence-based fashion to include the use of run and statistical process control charts to assess the impact of simulation-guided initiatives. Last, steps in developing a simulation program focused on PS/QI will be outlined with future opportunities for OTO-HNS simulation.

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