scholarly journals AN EXPERIMENTAL EVALUATION OF RASA PANCHAKA (ATTRIBUTES) OF FOLK MEDICINAL PLANT Andrographis Macrobotrys Nees

2020 ◽  
Vol 8 (8) ◽  
pp. 4116-4124
Author(s):  
Ranjitha S ◽  
Chandrakanth Bhat ◽  
Sudhakar Bhat ◽  
Reju krishnan
Keyword(s):  
Experimental Study ◽  
Medicinal Plants ◽  
Direct Perception ◽  
Albino Rats ◽  
Test Drug ◽  
Endothermic Reaction ◽  
Liver Disorders ◽  
Whole Plant ◽  
Animal Experimental Study ◽  
Wistar Albino Rats

Background and Objective: Folk medicinal plants are densely found in India which needs to be thorough-ly studied and documented. Andrographis Macrobotrys (Nees) is an erect, stout herb of Acanthaceae fami-ly is used in the treatment of snake bite, diarrhea, muscle pain, fever, jaundice, liver disorders and skin dis-ease by the tribes of Kerala. According to the principles of Ayurveda, basis for use of drug is by analysing its Rasapanchaka (attributes) namely rasa (taste), guna (qualities), vipaka (taste after digestion), virya (po-tency), and prabhava (special action). Hence assessment of Rasapanchaka is necessary for thorough knowledge of the drug. Aim of the present study is to evaluate the Rasa, Guna, Virya, Vipaka and prabha-va of Andrographis Macrobotrys Nees. Methods: Rasa of whole plant was assessed by direct perception by administering test drug to 25 volun-teers. Virya was assessed by exothermic and endothermic reaction of the drug with water in different con-centrations. Vipaka, guna and prabhava were determined through animal experimental study by adminis-tering drug to 12 Wistar Albino rats. Result and Conclusion: The assessment of study on rasapanchaka reveals that test drug possess Tiktha (bitter) rasa, Kashaya (astringent) anurasa, laghu (light), ruksha (dry), ushna (hot) guna, katu (pungent) vipaka, sheetha (cold) virya, pachana (digestive), lekhana (scraping) karma (action).

scholarly journals An Experimental Study to Evaluate the Anti-Diarrheal Activity of Bhuvaneshwara Rasa in Wistar Albino Rats

2021 ◽  
pp. 27-35
Author(s):  
Simi Jose ◽  
Chaitra L.V
Keyword(s):  
Experimental Study ◽  
Castor Oil ◽  
Raw Materials ◽  
Life Time ◽  
Drug Group ◽  
Albino Rats ◽  
Test Drug ◽  
Wistar Albino Rats ◽  
Important Disease

Atisara (Diarrhea) is most commonly encountered disease of the present era, due to unhealthy and irregular habits. Atisara (Diarrhea) finds a place as important disease in individual’s life as everyone suffers from it at least once in life time. Bhuvaneshwara rasa is a unique herbo-mineral formulation explained in Bhaishajya ratnavali indicated for all kinds of diarrhea cases. Bhuvaneshwara rasa is a potent formulation having Saindhava, Triphala, Yamani, Bilva peshika and Gruhadhooma. Materials and methods: Raw materials were screened and collected and the formulation selected for the present study Bhuvaneshwara rasa was prepared accordingly. Anti-diarrheal activity of Bhuvaneshwara rasa was evaluated experimentally in albino rats. Experimental study was conducted in 3 groups of animals for anti-diarrheal study each. Anti-diarrheal study was done by castor oil induced diarrhoea and castor oil induced enter-pooling method. Bhuvaneshwara rasa (test drug) and Loperamide are effective in controlling diarrheal episodes. Bhuvaneshwara rasa has shown significant Anti-diarrheal activity in both Castor oil -induced diarrhea and castor oil induced enteropooling, test drug effective than control. Result: Bhuvaneshwara rasa was prepared according to SOP. Test drug group have shown effect experimentally. Conclusion: Bhuvaneshwara rasa is a good anti-diarrheal drug. It can be administered in all types of Atisara.

scholarly journals Histopathologcal Effects of Methotrexate on Rat Kidney –An Experimental Study on Wistar Albino Rats.

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Kamaldeep Singh Balowria ◽  
◽  
Masooma Syed ◽  
Sheikh Tousia ◽  
Nafis Ahmad Faruqi ◽  
...  
Keyword(s):  
Experimental Study ◽  
Rat Kidney ◽  
Albino Rats ◽  
Wistar Albino Rats

Antipyretic activities of ethanolic extract of the whole plant of <i>Fagonia schweinfurthii</i> hadidi on albino rats- An experimental study

Spatula DD ◽  
2012 ◽  
Vol 2 (3) ◽  
pp. 159
Author(s):  
Manoj Rathore ◽  
Mahesh Sharma ◽  
Manoj Goyal ◽  
Gajendr Singh ◽  
Somdatt Gupta
Keyword(s):  
Experimental Study ◽  
Ethanolic Extract ◽  
Albino Rats ◽  
Whole Plant

scholarly journals Screening of anticonvulsant effect of carvedilol on electrically induced convulsions in Wistar albino rats

2020 ◽  
Vol 9 (12) ◽  
pp. 1803
Author(s):  
Biacin Babu ◽  
Madhavrao Chavan
Keyword(s):  
Albino Rats ◽  
High Dose ◽  
Anticonvulsant Effect ◽  
Low Doses ◽  
Test Drug ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Group Ii ◽  
Wistar Albino Rats

Background: Epilepsy is one of the major central nervous system disorders. The parent study aimed to screen the anticonvulsant effect of carvedilol on electrically induced convulsions in Wistar albino rats.Methods: This study was done in Wistar albino rats. A total of 30 rats were divided into 6 groups each of six rats. group-I (0.9% normal saline), group-II diphenylhydantoin (10 mg/kg/BW/ip), group-III carvedilol (1mg/kg/BW/PO), group-IV carvedilol (2 mg/kg/BW/PO) and group-V carvedilol (4 mg/kg/BW/PO). All the groups were administered drugs and subjected to electric shock. Scores of seizures and percentage of protection were recorded to compare between the groups. One was ANOVA (post hoc) followed by Dunnet t test applied to find the statistically significant between the groups.Results: Group-I showed significant difference compared to other groups. Group-II showed significant difference with group-III and IV not with V. High dose of test drug and standard drug showed similar results in percentage of seizures prevention. Control and low doses of test drugs showed significant difference compared to standard and high dose of test drug in seizures prevention.Conclusions: High of carvedilol showed significant seizures prevention compared to low doses and control group.

scholarly journals AQUEOUS EXTRACT OF WHOLE PLANT OF HYPTIS SUAVEOLENS (L.) POIT: AN ANTI-ULCER AGENT

2021 ◽  
Vol 10 (4) ◽  
pp. 3187-3190
Author(s):  
Yada Deepthi
Keyword(s):  
Control Group ◽  
Albino Rats ◽  
Mucus Production ◽  
Digestive Juice ◽  
Whole Plant ◽  
Pylorus Ligation ◽  
Hyptis Suaveolens ◽  
Entire Plant ◽  
Wistar Albino Rats ◽  
Different Doses

The aim of current experimental study was to determine anti-ulcer potential of Watery extricate of Hyptis suaveolens entire plant (AEHS) on the Wister strain albino rats. The Watery extricate of Hyptis suaveolens entire plant (in two different doses, 250mg/kg and 500 mg/kg) was allowed for anti-ulcer activity against Pylorus ligation induced model in Wistar albino rats. Omeprazole (20mg/kg) was used as standard for the evaluation of activity. Parameters like Proportion of Ulcer protection was reckoned based on Ulcer index and Digestive juice volume, pH and acidity of gastric juice, Mucus production and Pepsin estimation, tensile strength. The AEHS with 500 mg/kg dose was shown significant anti-ulcer activity when compared with the control group.

Impact of sperm retrieival on testis and epididymis: an experimental study using Wistar albino rats

2013 ◽  
Vol 59 (5) ◽  
pp. 261-269 ◽  
Author(s):  
Elumalai Prithiviraj ◽  
Sekar Suresh ◽  
Monica Manivannan ◽  
Seppan Prakash
Keyword(s):  
Experimental Study ◽  
Albino Rats ◽  
Wistar Albino Rats

Abstract P3-12-20: The impact of everolimus on radiation-induced pulmonary fibrosis in wistar albino rats: Results of an experimental study

2016 ◽  
Author(s):  
MF Eren ◽  
A Ay Eren ◽  
B Yücel ◽  
S Elagöz ◽  
Y Özgüven ◽  
...  
Keyword(s):  
Experimental Study ◽  
Pulmonary Fibrosis ◽  
Albino Rats ◽  
Radiation Induced ◽  
Wistar Albino Rats ◽  
The Impact

The effects of tamoxifen on radiation-induced pulmonary fibrosis in Wistar albino rats: Results of an experimental study

The Breast ◽  
2006 ◽  
Vol 15 (3) ◽  
pp. 455-459 ◽  
Author(s):  
Nuran Senel Bese ◽  
Cenk Umay ◽  
Sukru Yildirim ◽  
Sennur Ilvan ◽  
Ahmet Dirican ◽  
...  
Keyword(s):  
Experimental Study ◽  
Pulmonary Fibrosis ◽  
Albino Rats ◽  
Radiation Induced ◽  
Wistar Albino Rats
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