scholarly journals MEDICINAL LEECH FOR THE TREATMENT OF ACNE VULGARIS W.S.R. TO MUKHADUSHIKA: A RANDOMISED CLINICAL STUDY

AYUSHDHARA ◽  
2021 ◽  
pp. 3064-3070
Author(s):  
Gupta Sudesh ◽  
Sharma Sakshi ◽  
Prasher Aarushi ◽  
Sharma Kumar Arun ◽  
Manhas Raman
Keyword(s):  
Acne Vulgaris ◽  
Signs And Symptoms ◽  
Medicinal Leech ◽  
Inflammatory Disorder ◽  
Age Group ◽  
Time Saving ◽  
Chronic Inflammatory Disorder ◽  
Effective Time ◽  
The Face

Acne vulgaris is a chronic inflammatory disorder of the pilo-sebaceous follicles characterised by comedones, papules, pustules, nodules and often scars mainly seen on cheeks, chin, nose, forehead and upper trunk during adolescence. The symptoms of Acne vulgaris resemble Mukhadushika as per Ayurvedic classics. Acharya Sushruta has mentioned Mukhadushika as one of the Kshudra Rogas. In Mukhadushika, there are Shalmali kantak like eruptions on the face which are impregnated with Meda caused due to vitiation of Kaphadosha, Vatadosha and Raktadhatu which destroy the beauty of the face and makes the appearance ugly. The disease almost take place in adolescent and young age group prominently therefore is also known as Yuvanapidika. Acharya Sushruta stated Jalaukavacharana is the preferred method of bloodletting in Sukumara. Aim: To evaluate the efficacy of Jalaukavacharana in the management of Acne vulgaris w.s.r. to Mukhadushika. Methodology: Fourteen patients of age group 15-30 years having signs and symptoms of Mukhadushika were selected and four sittings of Jalaukavacharana on a seven day interval were given. Apart from treatment duration of 28 days, a follow-up was also done after 30 days. Results: Intervention was found to be highly significant (p<0.001) in Vedana, Kandu, Daha, number of Pidika, size of Pidika, Pidika ghanata, Shotha, Vaivarnyata. However, significant effect (p<0.05) was found in Vranavastu and non-significant result (p>0.05) was found in Srava. Conclusion: The results are satisfactory. Jalaukavacharana is proved to be an effective, time saving, affordable and acceptable treatment in Mukhadushika without causing any adverse effect.

scholarly journals A COMPARATIVE STUDY OF THE EFFICACY AND SAFETY OF 12 % GLYCOLIC ACID CREAM AND 10% AZELAIC ACID CREAM IN THE TREATMENT OF POST ACNE HYPERPIGMENTATION.

2021 ◽  
pp. 34-35
Author(s):  
Archana Rede ◽  
Sanjay N. Agrawal ◽  
Yoganand Kulkarni
Keyword(s):  
Comparative Study ◽  
Azelaic Acid ◽  
Glycolic Acid ◽  
Acne Vulgaris ◽  
Inflammatory Disorder ◽  
Efficacy And Safety ◽  
Common Complication ◽  
Pilosebaceous Unit ◽  
Inflammatory Lesions ◽  
Chronic Inflammatory Disorder

Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit that is associated with significant psychosocial repercussions. Post inflammatory hyperpigmentation is a most common complication seen after post acne. Therapeutic goal of treatment include promoting degradation of melanosomes and inhibiting their formation. Patient treated with Azelaic acid / Glycolic acid experienced of significant greater reduction in number of inflammatory lesions. This study focuses on the comparison of efficacy of 12% Glycolic acid and 10% Azelaic acid in treating post acne hyperpigmentation.

scholarly journals Interventions to Increase Adherence to a Gluten Free Diet in Patients with Coeliac Disease: A Scoping Review

2020 ◽  
Vol 2 (3) ◽  
pp. 318-326
Author(s):  
Humayun Muhammad ◽  
Sue Reeves ◽  
Sauid Ishaq ◽  
Yvonne Jeanes
Keyword(s):  
Coeliac Disease ◽  
Intervention Studies ◽  
Gluten Free Diet ◽  
Online Course ◽  
Dietary Adherence ◽  
Inflammatory Disorder ◽  
Gluten Free ◽  
Robust Methods ◽  
Chronic Inflammatory Disorder

Coeliac disease is a chronic inflammatory disorder of the small bowel, characterised by permanent intolerance to gluten. The only current and effective treatment for coeliac disease is a gluten free diet [GFD], however this is challenging for patients to adhere to. The review aims to identify published interventions designed to improve patients’ adherence to a GFD. Ten intervention studies were identified and included within the review; whilst heterogeneous in delivery, all included an educational, behavioural, and practical element. Five interventions significantly improved dietary adherence, these included follow-up appointments, a telephone clinic, an online course, cooking sessions and psychological support. All studies were small and used varied methods to assess adherence. There is a paucity of well-designed interventions to promote dietary adherence, in future more robust methods for ascertaining adherence is needed, we recommend greater inclusion of dietetic assessment and combining more than one method for assessing adherence.

scholarly journals Two-Stage Pediatric Penile Reconstruction after Postcircumcision Gangrene

2020 ◽  
Vol 05 (02) ◽  
pp. e95-e100
Author(s):  
Tarek Zayid ◽  
Mohamed O. Ouf ◽  
Amr Elbatawy ◽  
Serag M. Zidan ◽  
Abdelnaser Hamdy ◽  
...  
Keyword(s):  
Retrospective Cohort ◽  
Urethral Reconstruction ◽  
Corrective Surgery ◽  
Minor Complication ◽  
Time Saving ◽  
Flap Survival ◽  
Effective Time ◽  
Partial Necrosis ◽  
Groin Flap

Abstract Background Postcircumcision penile gangrene is a devastating complication that may lead to total or subtotal penile loss requiring penile reconstruction. Pediatric penile reconstruction poses diverse challenges for most plastic surgeon. Patients and Methods Retrospective cohort study of 12 children ranged from 6 to 36 months old suffered from total or partial penile loss secondary to electrocautery burn during circumcisions. Reconstruction was done by island groin flap for phallus in first stage and urethral reconstruction by tubularized scrotal flap 6 months later. The outcome was evaluated by assessment of flap survival, the esthetic appearance, urethral competence and rate of complication. Results Follow-up was ranged from 6 to 24 months. A new phallus of satisfactory dimensions was achieved in all cases. Complications included partial necrosis of the flap in two cases, fistulas in two cases, and stenosis of the urethral anastomosis in one case. These complications were successfully resolved by corrective surgery. Good satisfactory result regarded as shape and urination stream. Conclusion Penile reconstruction can be performed in children with good results and low complication rate. The use of island groin flap for phallus reconstruction followed by urethral reconstruction by tubularized scrotal flap 6 months later was found effective, time saving, and with minor complication.

scholarly journals Imaging in polymyalgia rheumatica

Reumatismo ◽  
2018 ◽  
Vol 70 (1) ◽  
pp. 51 ◽  
Author(s):  
N. Possemato ◽  
C. Salvarani ◽  
N. Pipitone
Keyword(s):  
Polymyalgia Rheumatica ◽  
Morning Stiffness ◽  
Imaging Techniques ◽  
Review Article ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Pet Ct ◽  
Ct And Mri

Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause clinically characterized by pain and prolonged morning stiffness affecting the shoulders and often the pelvic girdle and neck. Imaging has substantially contributed to defining PMR as a disease mainly involving extra-articular structures. This review article analyses the role of the different imaging techniques in the diagnosis and follow-up of patients with PMR with particular emphasis on the role of ultrasound, PET/CT and MRI.

scholarly journals DEPRESSION IN ACNE VULGARIS

2018 ◽  
Vol 25 (06) ◽  
pp. 892-895
Author(s):  
Naima Luqman ◽  
Niaz Maqsood ◽  
Wajih-Ur- Rehman
Keyword(s):  
Rating Scale ◽  
Acne Vulgaris ◽  
Severe Depression ◽  
Clinical Severity ◽  
Inflammatory Disorder ◽  
Mild Depression ◽  
Dermatology Department ◽  
Chronic Inflammatory Disorder ◽  
Severity Of Depression ◽  
Hospital Study

INTRODUCTION: Acne vulgaris is a chronic inflammatory disorder of pilo-sebaceous glands,which most commonly affect face and trunk. It is most prevalent in adolescent age group. Ithas been seen that acne can have profound social and psychological effects which are notnecessarily related to its clinical severity. Objectives: To determine the frequency and severity ofdepression among acne patients attending the outpatient dermatology department, of a tertiarycare hospital. Study Design: Descriptive study. Place & Duration of Study: Department ofDermatology, Bahawal Victoria Hospital, Bahawalpur from September, 2013 to November, 2013.Subjects & Methods: Informed written consent was taken from patients for the study, seventypatients of acne, diagnosed by consultant dermatologist were inducted. The severity of acnewas determined by Global Acne Grading System. Both genders were included, the age rangewas from 16 to 40 years. Those patients with concomitant dermatological, psychiatric diseasesand those receiving systemic isotretinoin were excluded. The patients fulfilling inclusioncriteria were assessed for depressive symptoms and Hamilton Depression rating scale wasadministered for severity of depression. Results: 70 patients were included in the study, amongthem 14 (20%) were male and 56 (80%) were females. Most of the acne patients were of the age16-20 years [24 (34.3%)]. Mild depression was seen in 26% patients (18%-were females and8%-males). Severe depression was present in 14% of patients, among which 11% were females& 3% were males. Very severe depression was noted in 18% patients among which 16% werefemale and 2% were males. Conclusions: it can be concluded that Dermatologists should paydue attention to the psychological/ mental state of the patient while clinically evaluating andtreating patients suffering from acne vulgaris

scholarly journals Evaluation of skin sensitivity in individuals presented with temporomandibular disorder

Revista CEFAC ◽  
2020 ◽  
Vol 22 (4) ◽  
Author(s):  
Giovanna Siqueira Faustino da Silva ◽  
Clarissa Evelyn Bandeira Paulino ◽  
Maurício Kosminsky ◽  
Luciana Moraes Studart-Pereira
Keyword(s):  
Temporomandibular Disorder ◽  
Signs And Symptoms ◽  
Age Group ◽  
Skin Sensitivity ◽  
Significance Level ◽  
Regional Block ◽  
The Face ◽  
Sensitivity Change ◽  
And Gender ◽  
Neuromuscular Electrostimulation

ABSTRACT Purpose: to identify the occurrence of a difference in skin sensitivity between analogous points on the face in individuals with temporomandibular disorder. Methods: a total of 60 individuals of both genders, aged 18 to 73 years, participated in the study. People classified with TMD signs and symptoms with the Fonseca Anamnestic Questionnaire were included. The skin sensitivity was evaluated with a Semmes-Weinstein esthesiometer. Sensitivity change was defined in this study as the occurrence of a difference between analogous points on both hemifaces. The localization of the points followed the regional block anatomical description and was confirmed with a neuromuscular electrostimulation device. The collected data were analyzed statistically with a 5% significance level. Results: the occurrence of a difference in sensitivity between the analogous points had a significant association with age group and severity of TMD. However, no association was perceived between sensitivity change and gender. Conclusion: in the population studied, the more severe the temporomandibular disorder, the greater the skin sensitivity change on the face. Also, the older the person, the higher the number of analogous points with a difference in sensitivity.

Recurrent Kimura’s disease of head and neck treated with intensity-modulated radiotherapy

2021 ◽  
Vol 14 (3) ◽  
pp. e239064
Author(s):  
Jeyaanth Venkatasai ◽  
Arvind Sathyamurthy ◽  
Jeba Karunya Ramireddy ◽  
Thomas Samuel Ram
Keyword(s):  
Intensity Modulated Radiotherapy ◽  
Kimura’S Disease ◽  
Inflammatory Disorder ◽  
Unknown Aetiology ◽  
Chronic Inflammatory Disorder ◽  
Intensity Modulated ◽  
Integrated Boost ◽  
Good Local Control ◽  
Primary Modality

Kimura’s disease (KD) is a rare, chronic inflammatory disorder of unknown aetiology, which commonly affects men of the Asian race. Here, we present a case capsule of a 39- year-old man with KD of the left cheek, managed initially by surgery alone. He developed local recurrence after 6 months and was treated with steroids and isotretinoin. Eventually, steroids were discontinued due to toxicity and the lesion progressively increased in size. The patient was successfully treated using intensity-modulated radiotherapy with simultaneous integrated boost as a primary modality with minimal adverse effects. The patient has good local control and cosmetic outcome with no radiation-related toxicity at a follow-up period of 28 months.

scholarly journals Lichen sclerosus: a clinical study

2017 ◽  
Vol 3 (4) ◽  
pp. 481
Author(s):  
Sandhyarani Kshetrimayum ◽  
Nandakishore Singh Thokchom ◽  
Vanlalhriatpuii . ◽  
N. A. Bishurul Hafi
Keyword(s):  
Systemic Disease ◽  
Lichen Sclerosus ◽  
Signs And Symptoms ◽  
Inflammatory Disorder ◽  
Systemic Diseases ◽  
Adequate Treatment ◽  
Balanitis Xerotica Obliterans ◽  
Chronic Inflammatory Disorder ◽  
Labia Minora ◽  
Uncommon Disease

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Lichen sclerosus (LS) is a chronic inflammatory disorder that preferentially affects the anogenital region and rarely extra genital sites. It is more common in women and has a bimodal peak of incidence. The objective of the study was to document the clinical, demographic pattern and associated systemic diseases of lichen sclerosus (LS) among patients attending skin OPD, RIMS, Imphal.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">All patients presenting with signs and symptoms suggestive of lichen sclerosus (LS) were studied for a period of 24 months from March 2014 to February 2016. Clinical examination and relevant investigations including histopathology were performed</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">A total of 54 patients were studied (17 males and 37 females). M:F ratio was 1:2.2. Majority belonged to 25-44 years age group (29.6%). Ano-genital LS comprised 81.4% of the cases. All patients presented with hypopigmented atrophic plaque (100%). The commonest site was prepuce (53.3%) in males and labia majora, labia minora and clitoris (62%) in females. There were 2 cases of balanitis xerotica obliterans (BXO). Ten patients (18.6%) had extragenital LSA and the sites involved were trunk, waist and extremities. Associated systemic diseases were detected in 6 patients. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Lichen sclerosus is not an uncommon disease. Varied presentations ranging from asymptomatic white patch to severe inflammation and scarring were noted. Complications especially with genital involvement can be prevented by early diagnosis and adequate treatment. Screening for associated systemic disease may prove useful.</span></p>

scholarly journals The Elliptical Aggregates – Idiopathic Granulomatous Mastitis

2020 ◽  
Vol 1 (1) ◽  
pp. 25-31
Author(s):  
Anubha Bajaj
Keyword(s):  
Granulomatous Inflammation ◽  
Reproductive Age ◽  
Inflammatory Disorder ◽  
Age Group ◽  
Granulomatous Mastitis ◽  
Idiopathic Granulomatous Mastitis ◽  
Chronic Inflammatory Disorder ◽  
True Incidence ◽  
Breast Fed ◽  
Reproductive Age Group

Idiopathic granulomatous mastitis was initially scripted in 1972 by Kessler and Wolloch and is cogitated as an infrequent, benign, chronic inflammatory disorder. It commonly implicates females of reproductive age group, especially women who have breast fed in the preceding five to six years. Idiopathic granulomatous mastitis is commonly discerned in Asia and Mediterranean region although true incidence is undetermined. Diverse ethnicities delineate a diverse disease prevalence. Elimination of adjunctive causes of granulomatous inflammation makes idiopathic granulomatous mastitis a diagnosis of exclusion. As per the natural history, idiopathic granulomatous mastitis is designated as a self limiting disorder 1.

scholarly journals A Prospective, Randomised, Controlled, Split-Face Clinical Trial to Assess the Safety and the Efficacy of Cold Atmospheric Plasma in the Treatment of Acne Vulgaris

2021 ◽  
Vol 11 (23) ◽  
pp. 11181
Author(s):  
Sigrid Karrer ◽  
Mark Berneburg ◽  
Florian Zeman ◽  
Michael Koller ◽  
Karolina Müller
Keyword(s):  
Acne Vulgaris ◽  
Atmospheric Plasma ◽  
Serious Adverse Events ◽  
Inflammatory Lesions ◽  
Cold Atmospheric Plasma ◽  
Moderate Reduction ◽  
The Face ◽  
Randomised Controlled ◽  
Split Face

The increase in antibiotic resistance requires effective non-antibiotic therapies for acne. Cold atmospheric plasma (CAP) inactivates bacteria and improves wound healing, but its effect on acne has not been investigated. The objective of this controlled split-face study was to assess safety and efficacy of CAP in moderate acne. One side of the face received 8–10 treatments with cold helium plasma within 4–6 weeks; follow-up was two and four weeks thereafter. Acne lesions were counted, followed by global acne severity ratings. Of the 34 patients included, 29 completed the study. No serious adverse events occurred. The two facial sides did not significantly differ in the number of inflammatory and non-inflammatory lesions. An interaction effect of number and type of treatment was found for inflammatory lesions. Lesion reduction after 10 treatments was significantly higher on the treated than on the untreated side. Percentage of patients reporting improved aesthetics was higher for the treated than for the untreated side after treatment completion (79% vs. 45%) and at the two- (72% vs. 45%) and four-week follow-up (79% vs. 52%). In conclusion, CAP was safe with excellent tolerability, showed moderate reduction in acne lesions and led to higher patient-based ratings of aesthetics than non-treatment.

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