scholarly journals Prevalece of Hepatitis A Virus in Libian Children

2021 ◽  
pp. 1-4
Author(s):  
Aisha Areaby Sehari ◽  
◽  
Ashraf M Ayad ◽  
Keyword(s):  
Parental Education ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Severe Infection ◽  
Cross Sectional Study ◽  
Teaching Hospitals ◽  
Serum Samples ◽  
Cross Sectional ◽  
Limited Host Range ◽  
Associated Risk Factors

Hepatitis A virus (HAV) is the most hepatotropic. This virus is responsible for the most forms of acute and benign hepatitis although fulminant hepatic failure can occur in 1% more often in adults. It is a member of Picornaviridae famil, it is a heat stable and has limited host range. The incidence of infection by Hepatitis A virus shows regional variation being highest in developing countries. Determination of age specific Hepatitis A virus (HAV) seroprevalence and the associated risk factors would help better plan for national preventive strategies including vaccination. We carried out a cross-sectional study on 315 children from Tripoli and Gharian cities in Libya during the years 2018-2020. The age range of the patients was 1-18 years and were from different socioeconomic status (SES) families.....attending teaching hospitals casualty seeking medical help and checkup. The indicators of SES included employment status, residence, number of family members, source of drinking water and social status. Serum samples were collected and investigated for HAV antibodies. The data were statistically analyzed. HAV antibodies were positive in 113 patients (36%) Males were 161(53%) while Females were 154 (49%). HAV antibodies was significantly higher among children of low SES,60 % by the age of 18 years compared to children of high SES, 35% by the same age. Crowded household and parental education were significantly associated with high seropositivity and seronegativity respectively. There is significant rate of seronegativity amongst the studied population especially those from richer backgrounds making them more susceptible to severe infection in future with concomitant complications. We propose that revision of national vaccination program should be considered to include Hepatitis A vaccination

Hepatitis A infection in patients with chronic viral liver disease: a cross-sectional study in Jahrom, Iran

2014 ◽  
Vol 143 (3) ◽  
pp. 534-539 ◽  
Author(s):  
A. AHMADI VASMEHJANI ◽  
D. JAVESHGHANI ◽  
R. BAHARLOU ◽  
M. SHAYESTEHPOUR ◽  
S. D. MOUSAVINASAB ◽  
...  
Keyword(s):  
Liver Disease ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Severe Disease ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sectional Study ◽  
Serum Samples ◽  
Cross Sectional ◽  
Chronic Hcv

SUMMARYInfection with hepatitis A virus (HAV) in patient with chronic liver disease (CLD; due to hepatitis B or hepatitis C) may cause severe disease and fulminant liver failure. This study aimed to determine the seroprevalence of HAV antibodies in patients infected with HCV or HBV in Iran (Jahrom city). A total of 159 patients with underlying CLD were recruited between September 2012 and February 2013. Serum samples were collected from each patient and tested for anti-HAV using enzyme-linked immunosorbent assay (ELISA). The overall seroprevalence of total anti-HAV was 79·2%. Patients aged 20–30 years had the lowest (28·3%) anti-HAV seropositivity and those aged >50 years had the highest (95%) seropositivity. The overall prevalence of anti-HAV in patients with chronic HCV and HBV infection was 93·7% and 77·1%, respectively. The anti-HAV seropositivity in liver cirrhosis patients was 100% compared to CLD patients. Because of low HAV immunity in younger CLD patients, vaccination against HAV should be considered.

Seroprevalence of contagious bovine pleuropneumonia in cattle of Punjab, Pakistan and assessment of risk factors

2019 ◽  
Author(s):  
Ahsan Anjum ◽  
Asim Aslam ◽  
Raheela Akhtar ◽  
Tahir Yaqub ◽  
Junaid Naseer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Export Market ◽  
Economic Losses ◽  
Enzyme Linked Immunosorbent Assay ◽  
Contagious Bovine Pleuropneumonia ◽  
Serum Samples ◽  
Cross Sectional ◽  
Associated Risk Factors

Contagious bovine pleuropneumonia (CBPP) is an important infectious disease of respiratory system of cattle, caused by Mycoplasma mycoides subspecies mycoides. A cross sectional study was conducted in Lahore, Kasur and Jhang districts of Punjab to determine the prevalence of CBPP. A total of 560 serum samples were examined for the specific antibodies against M. mycoides subspecies mycoides, using a sandwich enzyme-linked immunosorbent assay. Associated risk factors that were evaluated include age, gender and breed. In this study, the overall seroprevalence was 8.75%. The seroprevalence of CBPP in Lahore, Kasur and Jhang were 8.26, 8.20 and 10.06%, respectively, but no significance difference (P less than 0.05) was observed. Among the assessed potential predisposing factors, gender and breed were not significantly associated with the serological status of the animal (P greater than 0.05), in which the age affected significantly the positivity to CBPP (P less than 0.05). The highest seropositivity was observed in animals of more than 7 years of age (32.08%) followed by in 4-7 years of age (8.16%) and lowest in animals of less than 4 years old (0.79%). This study confirms the presence of CBPP in the state which could be a threat to livestock export market and warrants the implementation of control measures to mitigate the economic losses associated with the disease. 

Seroprevalence and associated risk factors ofToxoplasma gondiiinfection in the Korean, Manchu, Mongol and Han ethnic groups in eastern and northeastern China

2016 ◽  
Vol 144 (9) ◽  
pp. 2018-2024 ◽  
Author(s):  
X.-X. ZHANG ◽  
Q. ZHAO ◽  
C.-W. SHI ◽  
W.-T. YANG ◽  
Y.-L. JIANG ◽  
...  
Keyword(s):  
Risk Factors ◽  
Ethnic Groups ◽  
Cross Sectional Study ◽  
Northeastern China ◽  
Serum Samples ◽  
Cross Sectional ◽  
Study Region ◽  
Han Ethnicity ◽  
Associated Risk Factors ◽  
Undercooked Meat

SUMMARYA cross-sectional study was conducted from June 2013 to August 2015 to determine the seroprevalence and possible risk factors for humanToxoplasma gondiiinfection in Korean, Manchu, Mongol and Han ethnic groups in eastern and northeastern China. A total of 1842 serum samples, including Han (n= 802), Korean (n= 520), Manchu (n= 303) and Mongol (n= 217) groups, were analysed using enzyme-linked immunoassays to detect IgG and IgMT. gondiiantibodies. The overallT. gondiiIgG and IgM seroprevalences were 13·79% and 1·25%, respectively. Of these groups, Mongol ethnicity had the highestT. gondiiseroprevalence (20·74%, 45/217), followed by Korean ethnicity (16·54%, 86/520), Manchu ethnicity (13·86%, 42/303) and Han ethnicity (11·35%, 98/802). Multiple analysis showed that the consumption of raw vegetables and fruits, the consumption of raw/undercooked meat and the source of drinking water were significantly associated withT. gondiiinfection in the Han group. Likewise, having a cat at home was identified as being associated withT. gondiiinfection in the Korean, Manchu and Mongol groups. Moreover, the consumption of raw/undercooked meat was identified as another predictor ofT. gondiiseropositivity in the Mongol group. The results of this survey indicate thatT. gondiiinfection is prevalent in Korean, Manchu, Mongol and Han ethnic groups in the study region. Therefore, it is essential to implement integrated strategies with efficient management measures to prevent and controlT. gondiiinfection in this region of China. Moreover, this is the first report ofT. gondiiinfection in Korean, Manchu, and Mongol ethnic groups in eastern and northeastern China.

scholarly journals A Cross Sectional Study to Evaluate Awareness About Hepatitis A & E Among Students in Lahore

2021 ◽  
Vol 10 (3) ◽  
pp. 160-166
Author(s):  
Azka Rizvi ◽  
Naveed Ahmed ◽  
Ayesha Naeem ◽  
Waqas Saleem ◽  
Muhammad Ilyas ◽  
...  
Keyword(s):  
Biological Sciences ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Control Measures ◽  
Cross Sectional ◽  
Awareness Campaigns ◽  
Mode Of Transmission ◽  
Prevention And Control Measures

Background: The aim and objectives of the study were to determine the knowledge, attitude and practices among biological and non-biological students regarding Hepatitis A virus (HAV) and Hepatitis E virus (HEV). Methods: The present study was conducted by the Department of Microbiology, Pakistan kidney & liver institute and research center (PKLI & RC) at University of Veterinary and Animal Sciences (UVAS), Lahore, Pakistan. The study was conducted in November, 2019 to January, 2020. A total of 326 respondents (students) participated in the present study. Respondents filled a pre-tested structured questionnaire. The variables accessed were knowledge of the diseases including etiology, mode of transmission, and prevention and control measures. Results: Most 81.56% of respondents from biological sciences (B-S) group and 51.70% from non-biological sciences (N-B-S) had awareness about HAV/HEV. Furthermore, 72.06% of respondents from BS group and 13.60% of respondents from NBS group had knowledge about the mode of transmission and spread of HAV and HEV infection. Only 16.20% of students from B-S group were aware about importance of vaccination against HAV/HEV. While a very low prevalence was found about vaccination in N-B-S group that is only 4.76%. Conclusion: The study shows significance difference in the awareness level among students from biological sciences and non-biological sciences background. Respondents were found to misunderstand the hepatitis A & E infections with hepatitis B & C, which suggests that there is need to spread awareness about the differences in their spread and severity of these infections. Awareness campaigns should be conducted to make people aware of the ways HAV/HEV spreads, its mode of transmission, severity of infection and preventive measures to minimize its spread as well as chances to acquire HAV/HEV infections.

scholarly journals Sero-prevalence of anti-Leptospira antibodies and associated risk factors in rural Rwanda: A cross-sectional study

2021 ◽  
Vol 15 (12) ◽  
pp. e0009708
Author(s):  
Etienne Ntabanganyimana ◽  
Robert Giraneza ◽  
Vincent Dusabejambo ◽  
Appolinaire Bizimana ◽  
Camila Hamond ◽  
...  
Keyword(s):  
Acute Infection ◽  
Prevalence Ratio ◽  
Cross Sectional Study ◽  
Serum Samples ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Domestic Livestock ◽  
Associated Risk Factors ◽  
Asymptomatic Subjects ◽  
Crop Farmer

Background Leptospirosis is a zoonotic disease transmitted through the urine of wild and domestic animals, and is responsible for over 50,000 deaths each year. In East Africa, prevalence varies greatly, from as low as 7% in Kenya to 37% in Somalia. Transmission epidemiology also varies around the world, with research in Nicaragua showing that rodents are the most clinically important, while studies in Egypt and Chile suggest that dogs may play a more important role. There are no published studies of leptospirosis in Rwanda. Methods & findings We performed a cross-sectional survey of asymptomatic adults recruited from five occupational categories. Serum samples were tested using ELISA and Microscopic Agglutination Test (MAT). We found that 40.1% (151/377) of asymptomatic adults had been exposed to Leptospira spp. Almost 36.3% of positive subjects reported contact with rats (137/377) which represent 90.7% among positive leptospira serology compared with 48.2% of negative subjects (182/377) which represent 80.5% among negative leptospira serology (OR 2.37, CI 1.25–4.49) and 1.7 fold on prevalence ratio and 2.37 of odd ratio. Furthermore, being a crop farmer was significantly associated with leptospirosis (OR 2.06, CI 1.29–3.28). We identified 6 asymptomatic subjects (1.6%) who met criteria for acute infection. Conclusions This study demonstrates a high prevalence of leptospiral antibodies infection among asymptomatic adults in rural Rwanda, particularly relative to neighboring countries. Although positive subjects were more likely to report rat contact, we found no independent association between rats and leptospirosis infection. Nonetheless, exposure was high among crop farmers, which is supportive of the hypothesis that rats together with domestic livestock might contribute to the transmission. Further studies are needed to understand infecting Leptospira servers and elucidate the transmission epidemiology in Rwanda and identify means of host transmitters.

scholarly journals Seroprevalence and Associated Risk Factors of Brucellosis in Livestock and Residents of New Valley Governorate, Egypt

2020 ◽  
pp. 531-539
Author(s):  
Mohamed Said Diab ◽  
Sherif Abd Allah Zidan ◽  
Nermin Abdalla A. Hassan ◽  
Haitham Elaadli ◽  
Ahmed Mohamed Bayoumi
Keyword(s):  
Risk Factors ◽  
Raw Milk ◽  
Cross Sectional Study ◽  
Enzyme Linked Immunosorbent Assay ◽  
Human Brucellosis ◽  
Human Occupation ◽  
Serum Samples ◽  
Cross Sectional ◽  
Significant Difference ◽  
Associated Risk Factors

Brucellosis is a worldwide zoonotic disease which is now considered endemic in most parts of Egypt. A cross-sectional study was carried out from December 2018 to February 2020 to investigate the seroprevalence of brucellosis in humans and livestock residing in two regions located in New Valley Governorate, Egypt. A total of 1254 animals (673 cattle, 348 sheep, and 233 goats) and 523 human serum samples were examined for brucellosis using Rose Bengal test (RBT) and then randomly selected sera (15 from cattle, 7 from sheep, 3 from goats, and 45 from humans) were further analyzed by complement fixation test, enzyme-linked immunosorbent assay to compare and detect the sensitivity and specificity of RBT. The prevalence of brucellosis was 0% in cattle, sheep, and goats while it was 23.9% in humans using RBT. Concerning humans, there was a higher percentage of infection in EL Kharga (33.6%). The prevalence of this infection was also at a higher level among individuals aged above 40 years (28.57%). Furthermore, men (26.11%) were more inclined to be inflicted, compared to women (22.5%) with no significant difference. Considering the human occupation, abattoir workers were the most predominant group of people at risk (33.3%), followed by farmers (31.25%) and animal keepers (20.6%) while the lowest prevalence was demonstrated in the housewives where the prevalence was 18.8 %. As a result, risk factors of the age range, locality, time of infection, contact with animals, and occupational groups could significantly affect the prevalence of human brucellosis in the New Valley Governorate. In conclusion, brucellosis is an alarming problem among residents of the New Valley Governorate. Thus, reducing the prevalence in humans and animals in the region of study may include restriction of the marketing the raw milk and enhancing public health awareness.

scholarly journals Seroprevalence of Chlamydia trachomatis IgA, IgM and IgG Antibodies and Associated Risk Factors among Sexually Active Individuals at Saint Vincent de Paul Hospital in Dschang, West Cameroon

2021 ◽  
pp. 13-21
Author(s):  
Thomas Djifack Tadongfack ◽  
Irina Lydia Sudeu Nitcheu ◽  
Rodrigue Ngoune ◽  
Vanessa Rosine Nkouayep ◽  
Aline Camerl Nzeffouo Selabi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chlamydia Trachomatis ◽  
Protective Factor ◽  
Cross Sectional Study ◽  
Sexually Active ◽  
Serum Samples ◽  
Cross Sectional ◽  
Treatment Protocols ◽  
Clinical Complications ◽  
Associated Risk Factors

Background: Chlamydia trachomatis is the most common cause of sexually transmitted infections worldwide. Infections caused by this pathogen are usually symptomatic in men and asymptomatic in about 2/3 of women resulting in a variety of clinical complications. Aim: To determine the seroprevalence of immunological markers and the risk factors associated with the seropositivity to C. trachomatis infection in sexually active individuals visiting the Saint Vincent de Paul Hospital in Dschang, West region Cameroon Study Design: This was an analytical cross-sectional study conducted between July and September 2020 at Saint Vincent de Paul Hospital in Dschang, Cameroon. Methods: A total of 154 participants were recruited during the data collection period. An indirect ELISA method was used to analyse participant’s serum samples. Risk factors were assessed through univariate and multivariate logistic regression using SPSS 25. Results: The seroprevalence of C. trachomatis infection was 38.3% (95%CI: 30.6 - 46.0). Only 39.6% (95%CI: 31.6 - 47.3) of the study population had never been in contact with the bacterium. The reinfection rate among participants was 8.4% (95%CI: 4.0 - 12.8). Results revealed that being Male is a protective factor against the infection [aOR: 0.12; 95% CI: 0.03 - 0.56; P ꞊ .007]. The non-use of condom [aOR: 21.58; 95% CI: 3.53 – 132.06; P ꞊ .001] and having encountered three or more sexual partners [aOR: 9.90; 95%CI: 1.07 – 91.60; P ꞊ .043] were the significant predictors of Chlamydia seropositivity. Conclusion: The implementation of proactive strategies to curb down the spread of the infection is necessary in this locality. This can be done by providing NAATs to as many health facilities as possible, educating the population and standardizing treatment protocols.

scholarly journals A serosurvey of water-borne pathogens amongst canoeists in South Africa

1995 ◽  
Vol 115 (2) ◽  
pp. 299-307 ◽  
Author(s):  
M. B. Taylor ◽  
P. J. Becker ◽  
E. Janse Van Rensburg ◽  
B. N. Harris ◽  
I. W. Bailey ◽  
...  
Keyword(s):  
Antibody Response ◽  
South African ◽  
Health Risks ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
Cross Sectional Study ◽  
Polluted Water ◽  
Norwalk Virus ◽  
Sectional Study ◽  
Cross Sectional

SummaryCertain health risks have been associated with recreational exposure to faecally polluted water. Canoeing in certain South African waters is considered to be a high risk activity with regard to schistosomiasis. gastroenteritis and possibly hepatitis. In a cross-sectional study, a serosurvey was conducted amongst canoeists to ascertain whether or not they had a higher seroprevalence to hepatitis A virus. Norwalk virus andSchistosomaspp. than non-canoeists. In comparisons between the two groups, a significant association could not be demonstrated between canoeing and antibody response to hepatitis A and Norwalk viruses (P-values for age-adjustedχ2were 0·083 and 0·219 respectively), but a significant association could be demonstrated between canoeing and the antibody response to Schistosoma spp. (P> 0·001: age-adjusted).

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