PREPARATION AND PROPERTIES OF COLLAGEN SOLUTION

2020 ◽  
pp. 217-221
Author(s):  
A.F. Reyimov ◽  
A.S. Rafikov ◽  
D.O. Abdusamatova
Keyword(s):  
Collagen Solution

scholarly journals Modification of Collagen Properties with Ferulic Acid

Materials ◽  
2020 ◽  
Vol 13 (15) ◽  
pp. 3419 ◽  
Author(s):  
Beata Kaczmarek ◽  
Katarzyna Lewandowska ◽  
Alina Sionkowska
Keyword(s):  
Thin Films ◽  
Mechanical Properties ◽  
Ferulic Acid ◽  
Surface Properties ◽  
Apparent Viscosity ◽  
Young Modulus ◽  
Shear Tests ◽  
Elongation At Break ◽  
Collagen Solution ◽  
Significant Difference

Collagen materials are widely used in biomedicine and in cosmetics. However, their properties require improvement for several reasons. In this work, collagen solution as well as collagen films were modified by the addition of ferulic acid (FA). Thin collagen films containing FA were obtained by solvent evaporation. The properties of collagen solution have been studied by steady shear tests. The structure and surface properties of collagen thin films were studied. It was found that for collagen solution with 5% addition of FA, the apparent viscosity was the highest, whereas the collagen solutions with other additions of FA (1%, 2%, and 10%), no significant difference in the apparent viscosity was observed. Thin films prepared from collagen with 1 and 2% FA addition were homogeneous, whereas films with 5% and 10% FA showed irregularity in the surface properties. Mechanical properties, such as maximum tensile strength and elongation at break, were significantly higher for films with 10% FA than for films with smaller amount of FA. Young modulus was similar for films with 1% and 10% FA addition, but bigger than for 2% and 5% of FA in collagen films. The cross-linking of collagen with ferulic acid meant that prepared thin films were elastic with better mechanical properties than collagen films.

A new collagen solution with high concentration and collagen native structure perfectly preserved

RSC Advances ◽  
2015 ◽  
Vol 5 (106) ◽  
pp. 87180-87186 ◽  
Author(s):  
Pengwei Qi ◽  
Yuanyuan Zhou ◽  
Dalu Wang ◽  
Zhanhang He ◽  
Zhongjun Li
Keyword(s):  
Native Structure ◽  
High Concentration ◽  
Collagen Solution ◽  
Optical Photograph

Optical photograph of collagen solutions in different solvents.

Squeezing flow of collagen solution – Mathematical model of shear and elastic behavior

2015 ◽  
Author(s):  
Aleš Landfeld ◽  
Rudolf Žitný ◽  
Jan Skočilas ◽  
Jaromír Štancl ◽  
Martin Dostál ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Elastic Behavior ◽  
Squeezing Flow ◽  
Collagen Solution

Fabrication and Characterization of Mechanically Reinforced Collagen Sponge

2005 ◽  
Vol 288-289 ◽  
pp. 385-388
Author(s):  
Yosuke Hiraoka ◽  
Ueda Hiroki ◽  
Yu Kimura ◽  
Yasuhiko Tabata
Keyword(s):  
Cell Attachment ◽  
Average Pore Size ◽  
Collagen Sponge ◽  
Average Pore ◽  
Culture Studies ◽  
Collagen Solution ◽  
Freeze Dried ◽  
Interconnected Pore

This study describes an investigation of collagen sponge mechanically reinforced through the incorporation of poly(glycolic acid)(PGA) fiber. A collagen solution with PGA fiber homogeneously dispersed was freeze-dried, followed by dehydrothermal cross-linking to obtain collagen sponges incorporating PGA fiber. A collagen sponge without PGA fiber was prepared similarly by using the collagen solution. By scanning electron observation, the collagen sponges exhibited isotropic and interconnected pore structures with an average pore size of 180 µm, irrespective of PGA fiber incorporation. As expected, PGA fiber incorporation enabled the collagen sponge to significantly enhance the compression strength. In vitro cell culture studies revealed that the number of L929 fibroblasts initially attached was significantly greater for the collagen sponge incorporating PGA fiber than for the collagen sponge. In vitro cell proliferation studies revealed that the proliferation of cell was higher for the collagen sponge incorporating PGA fiber, by day 21, than the collagen sponge without PGA fiber. It is possible that shrinkage suppression results in the superior cell attachment and proliferation of sponge incorporating PGA fiber. After subcutaneous implantation into the backs of mice, the residual volume of collagen sponge incorporating PGA fiber was significantly large compared with that of collagen sponge. We concluded that the incorporation of PGA fiber is a simple way to reinforce collagen sponge without impairing the biocompatibility.

Effects of NaCl on the rheological behavior of collagen solution

2013 ◽  
Vol 25 (3) ◽  
pp. 137-144 ◽  
Author(s):  
Lian Duan ◽  
Jiheng Li ◽  
Conghu Li ◽  
Guoying Li
Keyword(s):  
Rheological Behavior ◽  
Collagen Solution

scholarly journals Morphology and thermal stability of bacterial cellulose/collagen composites

2014 ◽  
Vol 12 (9) ◽  
pp. 968-975 ◽  
Author(s):  
Mădălina Albu ◽  
Zina Vuluga ◽  
Denis Panaitescu ◽  
Dumitru Vuluga ◽  
Angela Căşărică ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Bacterial Cellulose ◽  
Freeze Drying ◽  
Collagen Gel ◽  
Positive Influence ◽  
Mechanical Tests ◽  
Mechanical And Thermal Properties ◽  
Force Microscopy ◽  
Collagen Solution ◽  
Thermal Stability Of

AbstractThe aim of this paper was to prepare composites of bacterial cellulose (BC) and collagen to evaluate both the effect of collagen on the morphological, mechanical and thermal properties of BC and the effect of BC on the thermal stability of collagen for designing composites with increased potential biomedical applications. Two series of composites were prepared, the first series by immersing BC pellicle in solutions of collagen obtained in three forms, collagen gel (CG), collagen solution (CS) and hydrolysed collagen (HC), followed by freeze drying; and the second series of composites by mixing BC powder in solutions of collagen (CG, CS and HC), also followed by freeze drying. The properties of obtained composites were evaluated by Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), mechanical tests, scanning electron microscopy (SEM) and atomic force microscopy (AFM). The results revealed that BC acts as a thermal stabilizer for CS matrix, while with CG matrix it interacts synergistically leading to composites with improved properties. On the other hand, the BC sheet impregnated with collagen has a significantly improved thermal stability. Collagen (as HC, CS or CG) has also a positive influence on the mechanical properties of lyophilized BC sheet. A four times increase of modulus was observed in BC/HC and BC/CG composites. and an increase of 60 times for BC/CS. The spectacular increase of elastic modulus and tensile strength in the case of BC/CS composite was explained by the easier penetration of collagen solution in the BC network and impregnation of BC fibrils as revealed by SEM and AFM analyzes.

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