scholarly journals Risk factors for structural and functional changes of the heart in coal industry workers

2021 ◽  
Vol 100 (7) ◽  
pp. 688-692
Author(s):  
Olga Yu. Korotenko ◽  
Egor S. Filimonov ◽  
Nikolay I. Panev
Keyword(s):  
Risk Factors ◽  
Coal Mining ◽  
Left Ventricular ◽  
Coal Industry ◽  
External Respiration ◽  
Underground Coal Mining ◽  
Functional Changes ◽  
Common Risk Factors ◽  
The Right ◽  
Open Coal

Introduction. Working conditions at workplaces of coal industry enterprises are characterized by harmful factors exceeding the maximum permissible levels. These include coal-rock dust, noise, vibration, sudden temperature changes, etc. Conversely, unfavourable working conditions increase the risk of developing not only occupational but also work-related diseases. The objective of the study was to study the influence of industrial and common risk factors for cardiovascular diseases on structural and functional changes in the heart in coal industry workers. Material and methods. The study included 130 workers in coal mines in the South of Kuzbass and 78 workers in open coal pits, ranging from 40 to 55 years. The exclusion criteria from the study were the presence of any somatic pathology that could lead to structural and functional changes in the heart. In addition, all subjects underwent echocardiography to determine the structural and functional indices of the heart. Results. Lower values of ejection fraction and longitudinal deformation of the left ventricle were found among the workers in underground coal mining. At the same time, a decrease in the latter was revealed in 19.3% of the miners versus 7.6% of the workers in open coal pits (p=0.025). There was no association between reducing left ventricular longitudinal deformation and common risk factors in coal mine workers, in contrast, to open coal pit workers. The initial manifestations of diastolic dysfunction of the right ventricle in the group of workers of underground coal mining were revealed, which in the correlation analysis had a relationship with the indices of external respiration function. Conclusion. The decrease in the global longitudinal left ventricular myocardial deformation among miners is not associated with the studied common cardiovascular risk factors. Still, it is related to the influence of a complex of unfavourable production factors. Reduced indices of external respiration function affect the initial manifestations of diastolic dysfunction of the right ventricle in the workers of underground coal mining.

Cardiorespiratory disorders in abdominal obesity in workers of coal mining enterprises in the south of Kuzbass

2021 ◽  
Vol 61 (3) ◽  
pp. 168-172
Author(s):  
Egor S. Filimonov ◽  
Olga Yu. Korotenko ◽  
Evgeniya V. Ulanova
Keyword(s):  
Coal Mining ◽  
Abdominal Obesity ◽  
Respiratory System ◽  
Myocardial Dysfunction ◽  
Visceral Obesity ◽  
Left Ventricular ◽  
Coal Industry ◽  
Open Pit ◽  
External Respiration ◽  
The South

Introduction. The wide prevalence of cardiovascular diseases and their close connection with obesity, especially abdominal, makes the question of the relationship of these disorders with the respiratory system highly relevant to the coal industry. Their working conditions are closely related to the harmful effects on production factors. The study aimed to study the main cardiorespiratory parameters in coal industry workers with abdominal obesity. Materials and methods. We explored 369 men, including 225 employees of coal mines and 114 workers of open-pit coal mining enterprises in the South of Kuzbass, aged from 40 to 55 years (the average age of miners - 46.2±0.36 years, workers of open-pit mines - 46.7±0.36 years, p=0.344). Scientists conducted a study of external respiration function on an analyzer of the pneumotachometric type "Spiro-Spectrum." We used the ultrasound system "Vivid E9", manufactured by General Electric, to define echocardiographic parameters. Results. The percentage of abdominal obesity among the coal mining industry employees in the south of Kuzbass was relatively high (more than 50%). At the same time, we detected arterial hypertension much more often. Scientists have found that the average values of the lungs' vital capacity and the volume of forced exhalation for the first second have decreased in both groups in the presence of abdominal obesity. Moreover, we found a pronounced deviation among the miners. Researchers associate the values of the leading echocardiographic indicators with the presence of visceral obesity. We identified high values of systolic pressure in the pulmonary artery and characteristic signs of diastolic myocardial dysfunction in the examined patients. The researchers also identified the most pronounced indices of right and left atrial volumes in miners. In underground workers, the data of correlation analysis indirectly indicate that an increase in waist circumference is not the main factor affecting the reduction in their left ventricular longitudinal deformation. But we can't say this for onshore coal mining workers, who have a moderate connection. Conclusions. Abdominal obesity harms the respiratory system of coal industry workers, more pronounced in miners. Visceral obesity is significantly associated with dysfunction of the right and left parts of the heart, both in miners and in coal mine workers.

5201Intra-cardiac thrombus in patients undergoing ventricular tachycardia ablation. a computed tomographic scan study

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
F Sacher ◽  
P Roumegou ◽  
J Duchateau ◽  
N Derval ◽  
A Denis ◽  
...  
Keyword(s):  
Risk Factors ◽  
Right Ventricle ◽  
Left Atrium ◽  
Left Ventricular ◽  
Embolic Event ◽  
Computed Tomographic ◽  
Cardiac Thrombus ◽  
Vt Ablation ◽  
The Right ◽  
Lv Aneurysm

Abstract Background Embolic event is one of the complications of VT ablation. This may be due to the presence of intra-cardiac thrombus before ablation. However, there is no clear consensus on how to rule out thrombus before the procedure. Objective We sought to examine the prevalence and risk factors of intra-cardiac thrombus with cardiac computed tomographic (CT) scan in patients undergoing scar-related VT ablation. Methods In absence of contra-indication, all patients undergoing scar-related VT ablation at our institution underwent contrast-enhanced cardiac CT within one week before ablation. 324 consecutive patients (292 male, 59±16 yo) have been included in this study. The etiology was ischemic cardiomyopathy (CMP) (n=191), arrhythmogenic right ventricular CMP (ARVC) (n=37), congenital CMP (n=11) or other CMP (n=85). LVEF was <40% in 154 patients (48%). Results Intra-cardiac thrombus was diagnosed in 29 (9%) patients: in the left atrium (n=8), in the right atrium (n=1), in the left ventricle (n=15), in the right ventricle (n=3), in right and left atrium (n=1), and in left atrium and right ventricle (n=1). Moreover in 2, a bilateral pulmonary embolism was identified. The population with thrombus was older (65±12 vs 58±16 years, p=0,005), with more permanent atrial fibrillation (AF) (28% vs 8%; p=0.005). Patients with left ventricular (LV) aneurysm were at higher risk of thrombus 50% vs 3% (p<0.001). The average CHADSVASC score was similar for both groups (2,5 vs 2,1; p=0.179). After matching for age and sex, only ischemic CMP and LV aneurysm were risk factors for thrombus. Because of arrhythmic storm, ablation was performed by epicardial approach only, in 5 patients with intra-ventricular thrombus and by retroaortic approach only, in 2 patients with LAA thrombus. No embolic event occurred during these procedures. Conclusion CT scans help eliminating intra-cardiac thrombus before VT ablation procedure. A high proportion of thrombus (9%) was identified. Whereas LV thrombus should systematically be ruled out before scar related VT ablation, in patients with AF, a LAA thrombus should also be eliminated as well as RV thrombus in patients with ARVC. Acknowledgement/Funding ANR-10-IAHU-04

P5272Right versus Left Ventricular Remodelling after Surgical myectomy for HOCM

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
M Abdelkhalek ◽  
A El Sawy ◽  
R Doss ◽  
A Samaan ◽  
M Donia ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Nyha Class ◽  
Left Ventricular ◽  
P Value ◽  
Peak Strain ◽  
Functional Changes ◽  
Septal Myectomy ◽  
Surgical Myectomy ◽  
The Right

Abstract Background Surgical myectomy for (HOCM) results in complex structural and functional changes. “Remodelling” in different cardiac chambers. To date, changes in the Right versus the left Ventricle have not been studied. Methods Fourty five patients (mean age = 32±16, 68% males) who underwent extended septal myectomy for LVOTO and Fourty “normal” controls (mean age = 32±12 years, 52% males) were studied by cardiac magnetic resonance imaging (CMR). The patients were studied pre-operatively and 6–18 months post-operatively (median = 9 months). The images were analysed by both commercial and in-house software. Results After myectomy. Follow up CMR showed changes in RV mass (21±5 to 23±7) g/m2, volume (60±15 to 66±12) ml/m2 and shape using 3 different methods. RV deformation parameters showed significant changes with circumferential strain (−8±2 to −14±4), filling (38±16 to 62±19) ml/s/m2 and ejection rate (−44±17 to −75±22). Changes in RV were substantially higher than those observed in the LV (Figure. 1, Table. 1). All patients reported significant symptomatic improvement with 31 (78%) patients in NYHA class I and 9 (22%) in class II at follow up. Significant reduction in peak gradient across the LVOT by 75%. Table 1. Summary of reported parameters related to RV Shape for pre and post operation HOCM patients and Normal Healthy Volunteers LV RV Pre Post Normal P-value Pre Post Normal P-value EDV ml/m2 75±18 81±14 73±10 0.005 60±15 66±12 71±12 0.002 ESV ml/m2 20±9 24±8 26±6 0.008 16±7 19±9 26±7 0.02 SV ml/m2 56±13 57±10 51±13 0.38 44±11 48±10 49±14 0.009 EF 74±7 70±7 65±5 0.001 74±8 72±7 64±6 0.228 Mass g/m2 74±33 62±29 27±8 0.0456 21±5 23±7 18±5 0.2100 PFR ml/m2 173±48 141±48 141±40 <0.0001 38±16 62±19 55±24 <0.0001 PER ml/m2 −179±35 −172±42 −144±42 0.29 −44±17 −75±22 −57±22 <0.0001 Peak Strain −20±3 −20±3 −20±3 0.49 −8±2 −14±4 −12±3 <0.0001 Conclusion LV septal myectomy is followed by structural and functional remodelling which is more extensive in the right than the left ventricle. The clinical significance of these findings needs further study.

scholarly journals The effect of left ventricular remodeling on the longitudinal myocardial kinetics of both heart ventricles in patients with arterial hypertension and cardiovascular risk factors

2019 ◽  
Vol 26 (3) ◽  
pp. 27-34
Author(s):  
O. S. Barabash ◽  
Yu. A. Ivaniv ◽  
I. M. Tumak ◽  
Y. R. Barabash
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Systolic Function ◽  
Left Ventricular ◽  
Concentric Hypertrophy ◽  
Diastolic Velocity ◽  
Eccentric Hypertrophy ◽  
The Right ◽  
Kinetics Of

The aim – to study the longitudinal kinetics of the left, right ventricles and interventricular septum (IVS), depending on the type of left ventricular (LV) remodeling in patients with arterial hypertension (AH) in combination with additional cardiovascular risk factors with preserved LV contractility, as well as to determine the correlation of changes in the right ventricular systolic and diastolic parameters estimated with the tissue pulsed-wave Doppler imaging (TDI) with the same indices of the LV and IVS. Materials and methods. The study included 71 patients (average age – 54) with essential AH (68 % men) with a normal LV ejection fraction. The patients had the obese stage 1, combined hyperlipidemia, 29.6 % of patients had type II diabetes, 33.8 % were smokers. The patients were distributed into 4 groups depending on the types of remodeling: 1 – normal geometry (12.7 %); 2 – concentric remodeling (47.9 %); 3 – concentric hypertrophy (35.2 %); 4 – eccentric hypertrophy (4.2 %). TDI of the left and right ventricles and IVS was performed, systolic and diastolic TDI indices were determined, and the index of isovolumic myocardial acceleration (IVA) was calculated for the right ventricle (RV). Results and discussion. The type of LV concentric hypertrophy negatively affects the longitudinal myocardial kinetics of LV and IVS in the study group. The early diastolic velocity Em and the systolic velocity Sm were significantly decreased for the LV and IVS, the late diastolic velocity Am was decreased for the IVS and the E/Em for LV ratio was notably increased. Among the diastolic RV TDI indices only the deceleration time DTEm was significantly longer in LV concentric remodeling and concentric hypertrophy, than in its normal geometry. The IVA index was decreased in changing the type of LV geometry from normal to eccentric hypertrophy, indicating worsening of the RV longitudinal myocardial systolic function. There was a close correlation between diastolic and systolic TDI indices of the RV and IVS, which potentially indicated the importance of IVS in the mechanism of interventricular interaction and its effect on the RV function. The reliable dependence of systolic and diastolic RV TDI indices on the LV contractility was established. Conclusions. The type of LV remodeling, especially concentric hypertrophy, negatively affects the longitudinal myocardial kinetics of both ventricles in patients with AH in combination with additional cardiovascular risk factors. IVA can be a sensitive diagnostic criterion in the detection of early myocardial disorders of the RV systolic function with the changes of the LV geometry in this category of patients. Indices of RV longitudinal myocardial kinetics are closely dependent on changes in the function of IVS, which has a leading role in the formation of interventricular interaction.

EXPERIENCE OF FOREIGN COUNTRIES IN APPLYING INNOVATIONS IN THE COAL INDUSTRY

2020 ◽  
Vol 13 (1) ◽  
pp. 170-175
Author(s):  
M.V. Chernyaev ◽  
◽  
E.N. Ageev ◽  
Keyword(s):  
Coal Mining ◽  
Coal Industry ◽  
Underground Coal Mining ◽  
Innovative Technologies ◽  
Foreign Countries

The article examines the trends in the development of innovative technologies in open and underground coal mining, digitalization of processes in the exploration and geodetic works of the coal industry, and features of their application

INFLUENCE OF RISK FACTORS FOR CARDIOVASCULAR DISEASES, HISTORY OF CARDIOVASCULAR DISEASES, AND STRUCTURAL AND FUNCTIONAL STATE OF THE HEART ON 3-YEAR SURVIVAL IN PERSONS 95 YEARS AND OLDER

2021 ◽  
pp. 727-733
Author(s):  
К.А. Ерусланова ◽  
А.В. Лузина ◽  
Ю.С. Онучина ◽  
В.С. Остапенко ◽  
Н.В. Шарашкина ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Diseases ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Risk Of Death ◽  
History Of ◽  
The Right

В последние годы появляется все больше работ, посвященных снижению воздействия классических факторов риска, негативно сказывающихся на выживаемости с возрастом. Целью исследования была оценка влияния сердечно-сосудистых заболеваний, их факторов риска и структурно-функциональных характеристик сердца на трехлетнюю выживаемость лиц 95 лет и старше. В исследовании участвовали 69 пациентов 95 лет и старше (98±1,9 года), из них 61 (88,4 %) женщина и 8 (11,6 %) мужчин. Через 3 года были получены данные о статусе жизни участников: 25 (36,2 %) были живы и 44 (63,8 %) умерли. По результатам проведенного однофакторного регрессионного анализа было определено, что факторы риска и анамнез сердечно-сосудистых заболеваний не ассоциированы с трехлетней выживаемостью. Однако в трехлетнем периоде риск смерти увеличивался в 3 раза при снижении ДАД <75 мм рт. ст., в 7,8 раза - при снижении ФВ ЛЖ <62 % и в 4,9 раза - при увеличении конечного диастолического размера правого желудочка >2,9 см. In recent years, more and more works have appeared that with age, classic risk factors that negatively affect the prognosis (cardiovascular diseases) lose their influence on life expectancy. The study aimed to assess the influence of cardiovascular diseases and their risk factors and structural and functional characteristics of the heart on three-year survival in people 95 years and older. The study involved 69 patients 95 years and older (98±1,9 years), 61 (88,4 %) were women. After 36 months, data were obtained on the participants’ status of life: 25 (36,2 %) were alive, and 44 (63,8 %) died. Based on the regression analysis results, it was determined that risk factors and history of cardiovascular diseases were not associated with 3-year survival. With a 3-year follow-up, the risk of death increases three times with a decrease in diastolic blood pressure less than 75 mm/Hg, 7,8 times with a decrease in left ventricular ejection fraction below 62 %, and 4,9 times with an increase in the end-diastolic size of the right ventricle by more than 2,9 cm.

Assessment of Environmental and Occupational Safety in Mining Industry during Underground Coal Mining

2020 ◽  
Vol 11 (3) ◽  
Author(s):  
Marat L. RUDAKOV ◽  
Konstantin A. KOLVAKH ◽  
Iana V. DERKACH
Keyword(s):  
Coal Mining ◽  
Computer Modelling ◽  
Geophysical Methods ◽  
Coal Industry ◽  
Effective Control ◽  
Complex Method ◽  
General Tendency ◽  
Underground Coal Mining ◽  
Rock Falls ◽  
Continuous Increase

Ensuring the ever-increasing demands of society for energy resources is a key problem for the development of the economy of all countries of the world. At this stage, to improve the living and working conditions of a person, the development of industry and transport, the growth of production based on scientific and technological progress, a continuous increase in energy use is required. Analysis of the environmental consequences of coal mining shows that the human impact on the environment in the process of economic activity becomes global. Therefore, the main goal of the work is to assess the environmental safety in production because of a decrease in rock mass during underground coal mining. The work analyses the levels of negative environmental impact of coal industry enterprises. The relationship between the key statistical indicator that affects the accident rate and the value of professional risk is demonstrated. It is shown that despite the general tendency to reduce the number of cases of fatal injuries to coal mine workers, the procedure for assessing the risk caused by rock falls needs to be improved. In this regard, when assessing occupational risk, it becomes relevant to use information from multifunctional systems of safety (MSS). The complex method of effective control of mountain pressure is illustrated by application of the developed methodology of computer modelling of geo-mechanical processes, instrumental and geophysical methods for protection and maintenance of mine workings at development of a coal seam of the Barentsburg field.

scholarly journals Treatment of Clostridium difficile infection in community teaching hospital: a retrospective study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Ali Elbeddini ◽  
Rachel Gerochi
Keyword(s):  
Risk Factors ◽  
Clostridium Difficile ◽  
Treatment Algorithm ◽  
Dual Therapy ◽  
Primary Objective ◽  
Watery Diarrhea ◽  
Drug Of Choice ◽  
Positive Stool ◽  
Common Risk Factors ◽  
The Right

Abstract Objectives Clostridium difficile infection (CDI) is responsible for 15–25% cases of health-care-associated diarrhea. The CDI treatment algorithm used at our hospital is adapted from the Infectious Diseases Society of America 2010 C. difficile guideline. The primary objective of this study was to assess the treatment adherence to our algorithm; this was defined as therapy consisting of the appropriate antibiotic, dose, route, interval, and duration indicated based on the disease severity and episode within 24 h of diagnosis. Furthermore, our study also described the population and their risk factors for CDI at our hospital. Methods This was a single-centre, retrospective cohort chart review of CDI cases that were diagnosed at admission or during hospitalization from June 1st, 2017 to June 30th, 2018. Cases were identified by a positive stool test along with watery diarrhea or by colonoscopy. Results Sixty cases were included, of which adherence to our algorithm was 50%. Overall, severe CDI had the highest treatment non-adherence (83%), and the biggest contributing factor was prescribing the wrong antibiotic (72%). In severe CDI, which warrants vancomycin monotherapy, wrong antibiotic consisted of metronidazole monotherapy (55%) or dual therapy with metronidazole and vancomycin (45%). Patients were mostly older, females being treated for an initial episode of mild-to-moderate CDI. Common risk factors identified were age over 65 years (80%), use of antibiotics (83%) and proton pump inhibitors (PPI) (68%) within the previous 3 months. The use of a PPI in this study, a modifiable risk factor without a clear indication, was 35%. Conclusion An area for antimicrobial stewardship intervention in CDI treatment at our hospital is prescribing the right antibiotic based on the CDI indication. In severe CDI, an emphasis should be on prescribing vancomycin monotherapy as the drug of choice. PPI use should be reassessed for tapering when appropriate.

Branch Retinal Vein Occlusion Associated with the 20210 G-to-A Prothrombin Variant

2000 ◽  
Vol 10 (2) ◽  
pp. 177-179 ◽  
Author(s):  
C. Peris Martínez ◽  
J.A. Aviñó Martínez ◽  
M. Díaz-Llopis ◽  
E. España Gregori ◽  
J.L. Menezo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Fluorescein Angiography ◽  
Medical History ◽  
Retinal Vein Occlusion ◽  
Branch Retinal Vein Occlusion ◽  
Laboratory Tests ◽  
Visual Loss ◽  
Vein Occlusion ◽  
Common Risk Factors ◽  
The Right

Purpose To describe a case of branch retinal vein occlusion (BRVO) in a patient who tested positive for the 20210 A allele of the prothrombin (PT) gene. Methods A 48-year-old man had visual loss in the right eye secondary to BRVO confirmed by ophthalmoscopy and fluorescein angiography. His medical history was not remarkable for common risk factors for retinal occlusive diseases. Results Laboratory tests for hypercoagulability were positive for PT 20210 A variant. The patient's family tested negative for the PT variant. Conclusions Laboratory tests for coagulopathy, including the PT 20210 A variant, should be added to the examination of patients with central or BRVO, especially if most common risk factors for thrombosis have been excluded.

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