scholarly journals Management of Vataja abhishyanda (Allergic conjunctivitis) with Gutika anjana and Punarnavadi eye drops: A comparative clinical study

2021 ◽  
Vol 12 (4) ◽  
pp. 842-849
Author(s):  
Shashi Prakash Gupta ◽  
Vaghela D B
Keyword(s):  
Marked Improvement ◽  
Allergic Conjunctivitis ◽  
Signs And Symptoms ◽  
Complete Relief ◽  
Eye Drops ◽  
Duration Of Treatment ◽  
Body Sensation ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Background: Vataja Abhishyanda is characterized by Toda (Pricking pain), Sangharsha (foreign body sensation), Achchasruta (watery discharge), Alpa Shopha (mild chemosis), Vishushka Bhava (feeling of dryness), Parushya (roughness) etc which are very similar to the most of signs and symptoms of the Allergic Conjunctivitis. It is one of the most common type of eye allergy and is widely experienced by global population. Aims and Objective: . To evaluate and compare the efficacy of Punarnavadi eye drops and Gutika Anjana in the management of Vataja Abhishyanda(Allergic conjunctivitis). Materials and methods: Total 104 patients diagnosed with symptoms and signs of Vataja Abhishyanda were selected from the outpatient department of Shalakya tantra. The selected patients were assigned randomly into two groups, group A (Punarnavadi eye drop) having 51 and group B (Gutika Anjana) having 50 patients. Duration of treatment was 8weeks with follow up for one month after the trial. Result: In Group A, 96.08% got complete relief after the completion of treatment, 03.92% got marked improvement. In Group B, 98% got complete relief after the completion of treatment, 2% got marked improvement. Conclusion: Gutika Anjana shows better relief in all sign and symptoms on the basis of percentage. The reason may be Anjana has maximum absorption due to more contact of time with the tissue which is responsible for better bioavailability.

scholarly journals Comparative clinical study of Nasya Karma and Shirodhara with Prapaundarikadi Taila in Ardhavabhedaka w.s.r. to Migraine

2020 ◽  
Vol 5 (05) ◽  
pp. 46-58
Author(s):  
Navyashree M S ◽  
Rashmi R
Keyword(s):  
Marked Improvement ◽  
Clinical Manifestations ◽  
Signs And Symptoms ◽  
Treatment Modalities ◽  
Age Group ◽  
Unilateral Headache ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B ◽  
Cardinal Feature

Background: Ardhavabhedaka is a type of Shiroroga with the cardinal feature of unilateral headache, which if left untreated leads to complications like blindness and hearing loss. This disease can be correlated to Migraine head-ache based on the clinical manifestations. Nasya Karma and Shirodhara are the prime treatment modalities for Shirorogas. Objectives: To evaluate the effects of Nasyakarma and Shirodhara in the management of Ardhavabhedhaka. Material and Methods: Patients presenting with the classical features of Ardhavabhedaka and between the age group of 18 to 60 years irrespective of sex were selected and allotted in Group A and B with 20 patients in each group. Group A was administered with Nasya with Prapaundarikadi Taila and Group B with Shirodhara with Prapaundarikadi Taila for 7 days. Result: Data was tabulated and analyzed using Student t-test, paired proportion test, which showed marked improvement in patients with Ardhavabhedaka in both the groups. Nasya and Shirodhara with Prapaundarikadi Taila is proved effective in all patients. According to percentage wise relief in the symptoms of Ardhavabhedaka in Group A and B, Group A showed comparatively better relief. Conclusion: On the basis of the results of this study, it can be clearly concluded that Nasya performed with Prapaundarikadi Taila provided significant relief in the signs and symptoms of Ardhavabhedaka than Shirodhara performed with Prapaundarikadi Taila.

scholarly journals A Randomized Comparative Clinical Study to evaluate the effect of Bodhi Vruksha Twak Kashaya with Madhu and Guduchi Kashaya in the Management of Vatarakta with special reference to Gouty Arthritis

2020 ◽  
Vol 5 (02) ◽  
pp. 22-29
Author(s):  
K. M. Bhavana ◽  
Umesh C. ◽  
Neelakanta Sajjanar ◽  
Gopala Krishna G.
Keyword(s):  
Special Reference ◽  
Gouty Arthritis ◽  
Signs And Symptoms ◽  
Renal Diseases ◽  
Comparative Clinical Study ◽  
Evolution Of Technology ◽  
Group A ◽  
Group B ◽  
Contemporary Medicine ◽  
Potential Signal

Background: Vatarakta is a disease which is said to affect the population indulging in sedentary lifestyle. In today’s era the evolution of technology has reached a point where pretty much anything is available at the touch of a button. The lifestyle of today’s population is breeding ground for diseases like Vatarakta. Based on the causes, signs and symptoms, Vatarakta may be correlated to gouty arthritis in contemporary medicine. Gout affects about 2.1 million worldwide. Its prevalence is increasing; moreover it is a potential signal for unrecognized co-morbidities like obesity, diabetes mellitus, hypertension and renal diseases. In India the prevalence of gout is 2-6 per 1000. The purpose of this study is to explore and find out an effective, less expensive, easily available and well accepted drug with minimal or no complications for this dreadful condition. Materials and Methods: 40 patients diagnosed with Vatarakta w.s.r Gouty Arthritis were assigned randomly into 2 groups. Group A, were administered Bodhi Vruksha Twak Kashaya 50ml B.I.D with Madhu and Group B were administered Guduchi Kashaya 50ml B.I.D for a duration of 30 days. Assessment was done on day 0, day 15, day 30, and day 45. Observations and Results: In the present study Group A showed statistical significant results in all the parameters except for Sandhishotha and group B showed statistical significant result in Sandhishoola, Sandhidaha, Sparshasahaishnuta and uric acid levels. Conclusion: Overall result shows patients treated with Guduchi Kashaya showed better results than patients treated with Bodhi Vruksha Twak Kashaya with Madhu in Vatarakta with special reference to Gouty Arthritis.

scholarly journals Comparison of efficacy of topical alcaftadine (0.25%) versus olopatadine (0.1%) in allergic conjunctivitis

2022 ◽  
Vol 7 (4) ◽  
pp. 630-633
Author(s):  
Kiran Kumar L ◽  
M S Smitha Gowda
Keyword(s):  
Allergic Conjunctivitis ◽  
Treatment Options ◽  
Signs And Symptoms ◽  
Outcome Variable ◽  
Eye Drops ◽  
Open Label ◽  
Parallel Group ◽  
Significant Efficacy ◽  
Group B ◽  
Olopatadine Hydrochloride

The most common atopic ocular condition in clinical practice is allergic conjunctivitis. One of the preferred treatment options for allergic Conjunctivitis is anti histamines eye drops. The study purpose is to compare the clinical efficacy between topical alcaftadine 0.25% and olopatadine hydrochloride 0.1% in allergic conjunctivitis patients.A prospective, randomized, open label, parallel group, comparative study was conducted on 60 Patients with bilateral allergic conjunctivitis (30 in each group) after taking an informed written consentand was evaluated from May 2018 to November 2018. Patients were randomized into 2 groups of 30 each, group A received topical Alcaftadine 0.25% twice daily and patients in Group B received topical olopatadine hydrochloride 0.1% twice daily for 2 weeks. The patients were evaluated on first visit (baseline) followed by 7 and 14 day after starting the treatment. At each visit signs and symptoms were evaluated and rated using a scale from 0-3(0-Absent, 1- mild, 2 moderate and 3- severe). The change from baseline in the mean scores of itching, hyperemia, photophobia and tearing on day 14 is the primary outcome variable.: The signs and symptoms of allergic conjunctivitis were reduced by 2 weeks from baseline after using both the drugs. Relative significant efficacy was achieved in alcaftadine group for Itching, hyperemia and photophobia, but not for tearing (p=0.3). When compared to 0.1% olopatadine hydrochloride, 0.25% alcaftadine is more effective in reducing the symptoms of all types of allergic conjunctivitis except those mentioned in exclusion criteria.

A Comparative Clinical Study on Phalatrikadi Kwata and Darvyadi Kwatha in the management of Kamala w.s.r. to Jaundice

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Kallanagouda H. ◽  
S. C. Sarvi
Keyword(s):  
Clinical Study ◽  
Dietary Habits ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Mucous Membranes ◽  
Comparative Clinical Study ◽  
Group A ◽  
Clinical Signs And Symptoms ◽  
Ayurvedic Treatment ◽  
Group B

Background: Jaundice (Kamala) is a yellowish pigmentation of the skin, the conjunctival membranes over the sclera (whitish of the eyes), and other mucous membranes caused by hyperbilirubinemia (increased levels of bilirubin in the blood). Today’s lifestyle with unhygienic and poor dietary habits and alcoholic habits etc. are responsible factors to promote hepatic damage which clinically reflects as Kamala Roga. The incidence of such causes resulting in Jaundice. In India it is 2.37-3.15 per 1000 population. The effect of Ayurvedic treatment was assessed in relation to improvement in overall clinical signs and symptoms. Objectives: To evaluate the effect of Phalatrikaadi Kwatha and Darvyadi Kwatha in Kamala Roga. Methodology: A comparative clinical study was conducted on Kamala for period of 15 days. The patients were divided into 2 groups. In Group A 20 patients were administered with Phalatrikadi Kwatha internally and in Group B 20 patients were administered with Darvyadi Kwatha internally. Results: Group A and Group B have shown statistically significant result. Group B treated with Darvyadi Kwatha showed better result compared with Group B treated with Phalatrikadi Kwatha.

A study on the effect of Janaranjanakam Anjana in the management of Senile Immature Cataract

2019 ◽  
Vol 4 (04) ◽  
Author(s):  
Shilpa Kamath ◽  
Rathi S.
Keyword(s):  
Visual Acuity ◽  
Marked Improvement ◽  
Signs And Symptoms ◽  
Senile Cataract ◽  
Slit Lamp ◽  
Near Vision ◽  
Mild Improvement ◽  
Age Dependent ◽  
Group A ◽  
Group B

Senile cataract is an important cause of age dependent visual impairment and blindness. Till date, an effective medical treatment for senile cataract has not been found out. The only treatment of choice is surgery. Considering the increased rate of incidence of senile cataract, on availability of effective medical measures, possible complications and contraindications surgery, the need arises to research for drugs that could effectively help in arresting the progression and disintegrate the opacification of lens proteins. The Symptoms such as blurriness of vision, Glare, Diplopia etc. are mentioned in senile immature cataract which can be correlated with Kaphaja Timira. Objective of the study was to evaluate the efficacy of Janaranjanakam Anjana and Vimalanjana in the management of SIMC and to compare the efficacy of Janaranjanakam Anjana and Vimalanjana in the management of SIMC. In present study 40 patients were randomly selected and divided into 2 groups, with 20 patients each. Group A patients were treated with Janaranjanakam Anjana for 60 days. Group B were treated with Vimalanjana for 60 days. After the treatment it was observed that there was statistically significant result in the main signs and symptoms i.e. blurring of vision, floaters, glare, visual acuity for distant and near vision and slit lamp bio-microscopy. Amongst 40 patients, 1 patient were getting no improvement, 12 patients were getting Mild improvement, 23 patients were getting Moderate improvement and 4 patients were getting Marked improvement.

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECTIVENESS OF RASONA TAILA AND GANDHARVAHASTADI ERANDA TAILA IN GRIDHRASI (SCIATICA)

2020 ◽  
pp. 15-22
Author(s):  
Athira.C ◽  
Ajay Bhat U
Keyword(s):  
Clinical Study ◽  
Sciatic Nerve ◽  
Statistical Tests ◽  
Medical Science ◽  
Signs And Symptoms ◽  
Lateral Aspect ◽  
Painful Condition ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Gridhrasi is a Vyadhi characterized by Stambha (stiffness), Ruk (pain), Toda (pricking pain), Spandana (twitching) etc. Though it is of two types – Vataja and Vatakaphaja, Vata being the prime cause for this condition has to be tackled to gain relief. Gridhrasi, according to its signs and symptoms can be compared to sciatica in modern medical science which is a painful condition in which pain commences from the buttock and radiates into the lower extremity along its posterior or lateral aspect, more or less comprising of the area of distribution of the sciatic nerve. Thus, this study was taken up to evaluate the efficacy of Rasona taila and Gandharvahastadi eranda taila in the management of Gridhrasi (Sciatica). Methods: In the present study, 60 subjects diagnosed with Gridhrasi were randomly selected and assigned into two equal groups Group A and Group B comprising 30 subjects each. Subjects of Group A received Rasona taila 10ml orally in morning before food and subjects of Group B received Gandharvahastadi eranda taila 10 ml orally in morning before food, both for duration of 21 days. The data obtained in both the groups were recorded, tabulated and statistically analyzed using appropriate statistical methods. Results: After obtaining all the necessary data, the results were formulated by applying suitable statistical tests. Group A showed better results statistically when compared to Group B. Conclusion: Rasona taila has better effects than Gandharvahastadi eranda taila both clinically and statistically in reducing the signs and symptoms of Gridhrasi.

scholarly journals COMPARATIVE CLINICAL STUDY OF APAMARGAKSHARATAILA INJECTION AND INFRARED COAGULATION IN THE MANAGEMENT OF ARSHA (1ST AND 2ND DEGREE HEMORRHOIDS)

2020 ◽  
Vol 04 (04) ◽  
pp. 2319-2323
Author(s):  
Rahul Madhukar Kondekar ◽  
Rajashri Patil
Keyword(s):  
Indian Population ◽  
Internal Hemorrhoid ◽  
Signs And Symptoms ◽  
Anorectal Disorders ◽  
Surgical Methods ◽  
Internal Hemorrhoids ◽  
Comparative Clinical Study ◽  
Group A ◽  
Infrared Coagulation ◽  
Group B

Introduction: In anorectal disorders, incidences of hemorrhoids and fissures are increasing in Indian population due to western lifestyle. Many surgical methods are available to cure anorectal disorders, but now a days, demand for Ayurveda and herbal preparation is increasing in society. Materials and Methods: In this study, ApamargaKsharaTaila Injection submucosal Route (Group A) and infrared coagulation (Group B) procedure were administered for the management of internal hemorrhoid (Arsha). This study was an open labelled, prospective, interventional study, in which patients of hemorrhoids [n=30(15eachgroup)] were selected from OPD of Institutional hospital. ApamargaKsharaTaila Injection application submucosally on internal hemorrhoids and IRC was applied at the base of hemorrhoids. In all the two groups, the patients were assessed every week for 4 weeks and were followed up for another 4 weeks for relief in signs and symptoms. Results: Obtained results were analyzed and encouraging results were observed after completion of the treatment. Conclusion: The study concluded that ApamargaKshara-Taila Injection is the most effective treatment for the management of internal hemorrhoid of 1st and 2nd de-gree in comparison to IRC procedure. Keywords: ApamargaKshartaila, Arsha, Ayurveda, hemorrhoids

scholarly journals A COMPARATIVE CLINICAL STUDY ON THE EFFECTIVENESS OF UDVARTANA WITH SIRAVYADHA IN THE MANAGEMENT OF SIRAJAGRANTHI (VARICOSE VEIN)

2020 ◽  
Vol 08 (11) ◽  
pp. 5021-5030
Author(s):  
Neethu Dev ◽  
Santosh Kumar J ◽  
SubhashRai N
Keyword(s):  
Varicose Vein ◽  
Varicose Veins ◽  
Signs And Symptoms ◽  
Lifestyle Changes ◽  
Lower Limbs ◽  
Prolonged Standing ◽  
Comparative Clinical Study ◽  
Upward Direction ◽  
Group A ◽  
Group B

Varicose vein of the lower limbs is one of such clinical condition that hampers the beauty of the legs. It is a very common condition, affecting up to three in 10 adults. Varicose veins affect up to 25% of women and 15% of men. By the age of 50, nearly 40% of women and 20% of men have significant vascular problems. The lifestyle changes, obesity, occupational pattern of prolonged standing and pregnancy are considered to be significantly contributing to this situation. Siravyadha, which is one among the types of Sasastra Rak-tamokashana is mentioned in the treatment of Sirajagranthi in our classics. It is considered as Ardha Chikitsa of Shalyatantra and is said to provide immediate results. Udvartana which is having Vatakapha-hara Twakprasadana and Siramukhavivechana property is said to be effective in Sirajagranthi. Also, the procedure is done in Pratiloma (upward) direction which results in Dridikarana of angas by toning them and relieves the symptoms of varicose vein. Hence an effort was made to evaluate the effect of Sira-vyadha by Vrihimukha Sastra and Udvartana with Kolakulathadi Churna in the management of Sira-jagranthi (varicose vein), this study was planned with the following aims. Objective: A detailed study on Sirajagranthi and its Management. To study the effect of Udvartana with Siravyadha in Sirajagranthi (varicose veins). To study the effect of Siravyadha in Sirajagranthi (varicose veins)., To compare the effi-cacy of both in Sirajagranthi (varicose veins). Method: The outcome of the study is evaluated clinically on a minimum of 60 patients with Sirajagranthi, divides 2 groups A and B. Group A received Udvartana for 7days and then Siravyadha on 8th day. Group B received Siravyadha for 1 day and followed by Pathya for 7days.The duration of study was 28days in both the groups and observations were made on be-fore and after the treatment (0th, 8th and 28th day). Data obtained was statistically analysed and interpreted. Results: The results were assessed based on the relief obtained to the subjective and objective parameters and was taken for consideration for the study and were found statistically significant on all the parameters (p<0.05). Conclusion: From the study it is evident that effectiveness of Udvartana along with Siravyadha is more significant in reducing the signs and symptoms of Sirajagranthi.

To evaluate the efficacy of Siravyadha and Basti in the management of Siraja Granthi (Varicose Vein) - A Comparative Clinical Study

2017 ◽  
Vol 2 (05) ◽  
Author(s):  
Mohan Baban Dagu ◽  
N. B. Mashetti ◽  
Umapati C. Baragi
Keyword(s):  
Clinical Study ◽  
Complete Remission ◽  
Varicose Vein ◽  
Varicose Veins ◽  
Signs And Symptoms ◽  
Human Beings ◽  
Excellent Response ◽  
Comparative Clinical Study ◽  
Group A ◽  
Group B

Background: In this changed lifestyle of human beings, he has become a victim of several diseases, amongst them one is Varicose Veins, which are caused due to long standing or sitting in chairs which causes extra load on veins to pump the blood against gravity towards the Heart, especially the veins of the legs. Finally the veins get fatigued that leads to dilation and cause Varicosity in veins. Objectives: To compare the effect of Siravyadhana and Basti in the management of Siraja Granthi (Varicose Vein). Methods: Cases presenting with classical signs and symptoms of Siraja Granthi were randomly divided into 2 groups. Group A was treated with Siravyadhana and Group B were subjected for Sahacharadi Basti. The data was collected before treatment and after 8th day and 30th days. The obtained data was statistically analyzed. Results: 20 patients in Group A, 93.33% reduction was seen in Shoola, while 93.02% reduction was found in Group B. In Gaurava 86.36% reduction was found in Group A and 85.71% reduction was seen in Group B. Shotha was decreased by 67.74% in Group A, while 62.65% in Group B. In Sira Utseda, 54.05% reduction was seen in Group A and 47.36% reduction in Group B. Conclusion: Group A, cases showed better improvement. Out of 20 patients, 2 patients got complete remission in Group A, 2 patients showed excellent response, while in Group B, 6 patients showed excellent response, In Group A and B, 11 and 8 patients showed good response respectively. In Group A and B, 5 and 6 patients showed moderate response.

scholarly journals A comparative clinical study on Madhusiktadi Lepa with and without Siravyadha in the management of Padadari

2020 ◽  
Vol 5 (04) ◽  
pp. 50-56
Author(s):  
Varsha M. Bhiradi ◽  
Prasadshakti G. Gannur ◽  
N.B. Mashetti
Keyword(s):  
Statistical Analysis ◽  
Clinical Study ◽  
Treatment Group ◽  
Marked Improvement ◽  
Comparative Clinical Study ◽  
Group A ◽  
Patient Responses ◽  
Group B ◽  
The Individual ◽  
Apparently Healthy

Movement is one of the important gifts of God to mankind. If the individual has proper movements then it is indicative of undisturbed health. In some disorders foot movement are impaired; Crack foot syndrome is one such disorder where the person is apparently healthy but unable to walk because of pain, bleeding coupled with itching. In Ayurveda, it is referred as Padadari. The disease involves the Vatadosha leading to dryness, cracks, and fissures. The symptoms may include Vedana, Kandu, Daha, Raktasrava. So, in case of Padadari Acharyas’ explained Snehan, Swedan, Siravyadha followed by Lepa are advised as line of treatment. So, in this study two modalities viz. Siravyadha and Lepa are selected. The study was carried out on 60 patients. These patients were divided into two groups A and B each of 30 patients. Group A patients received Madhusiktadi Lepa and group B received Siravyadha with Madhusiktadi Lepa. Considering thorough statistical analysis of various study parameters and patient responses to the treatment, it is observed that Group B treatment has shown relatively better performance than group A treatment. Group B treatment has shown 53.26% patients completely cured (76-100% cure) and 46.66% patients shown marked improvement which is between 51-75% cure. Whereas group A treatment has shown 39.9 % patients were completely cured (76-100% cure) and 60.0% marked improvement (51-75% cure).

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